Homo sapiens

104 known processes

USP22

ubiquitin specific peptidase 22

(Aliases: KIAA1063,USP3L)

USP22 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
histone h3 acetylation GO:0043966 45 1.000
covalent chromatin modification GO:0016569 254 0.998
internal peptidyl lysine acetylation GO:0018393 97 0.997
histone acetylation GO:0016573 93 0.995
chromatin modification GO:0016568 298 0.988
chromatin organization GO:0006325 351 0.986
histone deubiquitination GO:0016578 16 0.983
internal protein amino acid acetylation GO:0006475 101 0.973
histone modification GO:0016570 251 0.973
peptidyl lysine acetylation GO:0018394 101 0.970
protein acetylation GO:0006473 116 0.930
peptidyl lysine modification GO:0018205 144 0.818
protein acylation GO:0043543 138 0.612
protein deubiquitination GO:0016579 79 0.527
glycosylation GO:0070085 71 0.485
protein modification by small protein removal GO:0070646 92 0.424
glial cell migration GO:0008347 4 0.422
Fly
generation of neurons GO:0048699 152 0.418
Fly
protein glycosylation GO:0006486 62 0.415
histone h4 k12 acetylation GO:0043983 6 0.303
lipid catabolic process GO:0016042 84 0.296
smad protein signal transduction GO:0060395 10 0.278
cellular ketone metabolic process GO:0042180 80 0.270
regulation of cellular ketone metabolic process GO:0010565 50 0.267
adult locomotory behavior GO:0008344 1 0.263
lipid localization GO:0010876 106 0.240
cell development GO:0048468 328 0.227
Fly
macromolecule glycosylation GO:0043413 63 0.219
cell morphogenesis GO:0000902 296 0.213
Fly
morphogenesis of embryonic epithelium GO:0016331 4 0.209
neuron differentiation GO:0030182 138 0.208
Fly
locomotory behavior GO:0007626 1 0.202
cellular lipid catabolic process GO:0044242 65 0.199
system process GO:0003008 349 0.196
regulation of cellular amine metabolic process GO:0033238 11 0.194
enzyme linked receptor protein signaling pathway GO:0007167 303 0.188
posttranscriptional regulation of gene expression GO:0010608 213 0.184
ganglioside catabolic process GO:0006689 3 0.184
cellular component morphogenesis GO:0032989 314 0.176
Fly
neuron projection development GO:0031175 106 0.174
Fly
glycoprotein metabolic process GO:0009100 110 0.156
regulation of cellular ketone metabolic process by positive regulation of transcription from rna polymerase ii promoter GO:0072366 1 0.155
glycoprotein biosynthetic process GO:0009101 91 0.152
hindbrain development GO:0030902 3 0.148
maintenance of location GO:0051235 112 0.146
cell morphogenesis involved in neuron differentiation GO:0048667 44 0.145
Fly
neuron development GO:0048666 113 0.144
Fly
tube closure GO:0060606 3 0.141
carbohydrate derivative biosynthetic process GO:1901137 207 0.141
histone h4 acetylation GO:0043967 47 0.139
transmission of nerve impulse GO:0019226 11 0.136
neurogenesis GO:0022008 169 0.134
Fly
lipid metabolic process GO:0006629 381 0.133
cell morphogenesis involved in differentiation GO:0000904 144 0.132
Fly
embryonic epithelial tube formation GO:0001838 4 0.131
positive regulation of cellular component organization GO:0051130 376 0.131
chromatin remodeling GO:0006338 55 0.130
neural tube formation GO:0001841 3 0.127
membrane lipid metabolic process GO:0006643 53 0.127
oogenesis GO:0048477 2 0.126
regulation of cellular carbohydrate metabolic process GO:0010675 47 0.125
female gamete generation GO:0007292 2 0.120
nervous system development GO:0007399 293 0.119
Fly
positive regulation of organelle organization GO:0010638 195 0.117
single organism carbohydrate metabolic process GO:0044723 193 0.113
n terminal protein amino acid modification GO:0031365 13 0.111
regulation of cellular amino acid metabolic process GO:0006521 6 0.106
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 125 0.098
amine metabolic process GO:0009308 44 0.098
cellular lipid metabolic process GO:0044255 303 0.098
regulation of glucose metabolic process GO:0010906 28 0.096
sphingolipid metabolic process GO:0006665 38 0.094
regulation of carbohydrate metabolic process GO:0006109 54 0.094
cellular macromolecular complex assembly GO:0034622 324 0.091
n terminal peptidyl lysine acetylation GO:0018076 4 0.089
somitogenesis GO:0001756 2 0.089
cellular amine metabolic process GO:0044106 41 0.088
neural tube closure GO:0001843 3 0.087
liposaccharide metabolic process GO:1903509 27 0.084
segmentation GO:0035282 4 0.084
regulation of protein stability GO:0031647 87 0.084
growth GO:0040007 202 0.078
regulation of cell cycle GO:0051726 393 0.078
neuronal action potential GO:0019228 9 0.076
regulation of membrane potential GO:0042391 95 0.075
lytic vacuole organization GO:0080171 24 0.074
positive regulation of chromosome organization GO:2001252 41 0.074
negative regulation of protein metabolic process GO:0051248 391 0.073
regulation of cell cycle process GO:0010564 266 0.072
metencephalon development GO:0022037 2 0.071
positive regulation of cellular amine metabolic process GO:0033240 7 0.071
neuron projection morphogenesis GO:0048812 50 0.070
Fly
regulation of transcription by chromatin organization GO:0034401 1 0.068
negative regulation of cell proliferation GO:0008285 228 0.067
hexose metabolic process GO:0019318 55 0.066
spermatid differentiation GO:0048515 4 0.066
neurotransmitter secretion GO:0007269 4 0.065
cellular macromolecule catabolic process GO:0044265 380 0.063
Fly
positive regulation of catabolic process GO:0009896 310 0.063
protein modification by small protein conjugation GO:0032446 342 0.062
post embryonic development GO:0009791 2 0.061
positive regulation of dna templated transcription elongation GO:0032786 18 0.061
small gtpase mediated signal transduction GO:0007264 78 0.060
monosaccharide metabolic process GO:0005996 74 0.059
cell projection organization GO:0030030 252 0.058
Fly
ceramide metabolic process GO:0006672 25 0.058
negative regulation of cell differentiation GO:0045596 171 0.056
positive regulation of gluconeogenesis GO:0045722 1 0.055
cellular response to organonitrogen compound GO:0071417 124 0.054
cellular response to endogenous stimulus GO:0071495 336 0.052
single organism membrane organization GO:0044802 268 0.052
fucosylation GO:0036065 4 0.052
cellular carbohydrate metabolic process GO:0044262 84 0.051
negative regulation of mrna metabolic process GO:1903312 15 0.049
vesicle mediated transport GO:0016192 371 0.048
multicellular organismal signaling GO:0035637 34 0.048
purine ribonucleoside metabolic process GO:0046128 437 0.048
positive regulation of cellular catabolic process GO:0031331 284 0.048
histone h3 k14 acetylation GO:0044154 2 0.047
cellular response to hormone stimulus GO:0032870 125 0.046
multicellular organismal aging GO:0010259 3 0.046
regulation of mitotic cell cycle GO:0007346 189 0.045
cellular response to peptide hormone stimulus GO:0071375 56 0.045
regeneration GO:0031099 4 0.045
cellular response to nitrogen compound GO:1901699 144 0.044
tissue regeneration GO:0042246 3 0.044
determination of adult lifespan GO:0008340 2 0.043
cellular protein catabolic process GO:0044257 261 0.043
Fly
action potential GO:0001508 34 0.043
regulation of cellular ketone metabolic process by regulation of transcription from rna polymerase ii promoter GO:0072364 3 0.042
neuromuscular process controlling posture GO:0050884 2 0.042
secretion GO:0046903 254 0.042
response to nitrogen compound GO:1901698 184 0.042
positive regulation of carbohydrate metabolic process GO:0045913 21 0.041
neurological system process GO:0050877 163 0.040
striated muscle contraction GO:0006941 52 0.040
secretion by cell GO:0032940 226 0.040
wnt signaling pathway GO:0016055 156 0.040
regulation of growth GO:0040008 165 0.039
endocytosis GO:0006897 159 0.039
transcription elongation from rna polymerase ii promoter GO:0006368 18 0.038
negative regulation of cellular protein metabolic process GO:0032269 353 0.038
tube development GO:0035295 125 0.038
epithelium development GO:0060429 227 0.038
neuromuscular process controlling balance GO:0050885 7 0.037
ribonucleoside triphosphate metabolic process GO:0009199 412 0.036
sensory perception GO:0007600 103 0.036
aminoglycan metabolic process GO:0006022 39 0.036
regulation of secretion GO:0051046 194 0.036
cellular response to insulin stimulus GO:0032869 41 0.035
glycosyl compound catabolic process GO:1901658 413 0.035
cell cycle phase transition GO:0044770 173 0.035
response to hormone GO:0009725 175 0.034
axonogenesis GO:0007409 31 0.034
Fly
regulation of dna templated transcription elongation GO:0032784 23 0.033
nucleoside phosphate catabolic process GO:1901292 412 0.033
rho protein signal transduction GO:0007266 26 0.033
midbrain development GO:0030901 45 0.032
canonical wnt signaling pathway GO:0060070 116 0.032
regulation of gene expression epigenetic GO:0040029 73 0.032
carbohydrate metabolic process GO:0005975 207 0.032
regulation of histone acetylation GO:0035065 19 0.032
carbohydrate biosynthetic process GO:0016051 42 0.032
behavior GO:0007610 112 0.031
sensory perception of mechanical stimulus GO:0050954 37 0.031
purine ribonucleoside catabolic process GO:0046130 398 0.031
cytoplasmic transport GO:0016482 379 0.031
glucose metabolic process GO:0006006 45 0.031
rna interference GO:0016246 4 0.031
purine nucleoside triphosphate metabolic process GO:0009144 412 0.031
sensory perception of sound GO:0007605 37 0.030
spermatid development GO:0007286 4 0.029
nucleotide catabolic process GO:0009166 408 0.029
embryonic morphogenesis GO:0048598 85 0.029
myoblast fusion GO:0007520 1 0.029
muscle system process GO:0003012 81 0.028
regulation of glycoprotein metabolic process GO:1903018 19 0.028
negative regulation of smoothened signaling pathway GO:0045879 3 0.028
anatomical structure formation involved in morphogenesis GO:0048646 284 0.028
negative regulation of synaptic transmission GO:0050805 2 0.028
cellular response to oxygen containing compound GO:1901701 276 0.028
purine nucleotide catabolic process GO:0006195 405 0.028
reproductive process GO:0022414 106 0.028
regulation of histone modification GO:0031056 47 0.027
chemical homeostasis GO:0048878 306 0.027
mitotic cell cycle process GO:1903047 286 0.026
single organism reproductive process GO:0044702 98 0.026
regulation of purine nucleotide metabolic process GO:1900542 264 0.026
sphingolipid catabolic process GO:0030149 8 0.026
golgi vesicle transport GO:0048193 80 0.026
purine containing compound catabolic process GO:0072523 411 0.026
ribonucleoside triphosphate catabolic process GO:0009203 391 0.025
muscle contraction GO:0006936 73 0.025
single organism cellular localization GO:1902580 332 0.025
regulation of immune response GO:0050776 201 0.025
telencephalon development GO:0021537 17 0.025
response to salt stress GO:0009651 3 0.024
neuromuscular junction development GO:0007528 3 0.024
response to insulin GO:0032868 45 0.024
gtp metabolic process GO:0046039 239 0.024
regulation of nucleotide metabolic process GO:0006140 269 0.024
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.024
mitochondrion organization GO:0007005 156 0.023
response to oxygen containing compound GO:1901700 369 0.023
regulation of protein catabolic process GO:0042176 155 0.023
modification dependent macromolecule catabolic process GO:0043632 212 0.023
Fly
positive regulation of cell cycle GO:0045787 140 0.023
regulation of purine nucleotide catabolic process GO:0033121 205 0.023
positive regulation of cellular carbohydrate metabolic process GO:0010676 16 0.023
protein localization to organelle GO:0033365 280 0.023
purine nucleoside catabolic process GO:0006152 398 0.023
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.023
membrane organization GO:0061024 292 0.023
syncytium formation by plasma membrane fusion GO:0000768 2 0.023
positive regulation of cell proliferation GO:0008284 301 0.022
synaptic vesicle exocytosis GO:0016079 3 0.022
epithelial tube morphogenesis GO:0060562 38 0.022
protein catabolic process GO:0030163 325 0.022
Fly
regulation of nucleoside metabolic process GO:0009118 209 0.022
multi organism reproductive process GO:0044703 54 0.022
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.022
organelle fission GO:0048285 149 0.021
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.021
regulation of chromosome organization GO:0033044 103 0.021
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.021
protein o linked glycosylation GO:0006493 21 0.021
mrna processing GO:0006397 133 0.021
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.021
positive regulation of glucose metabolic process GO:0010907 12 0.021
regulation of chromatin modification GO:1903308 51 0.021
reproduction GO:0000003 63 0.021
actin filament based process GO:0030029 224 0.020
glycosphingolipid metabolic process GO:0006687 13 0.020
response to peptide GO:1901652 65 0.020
regulation of ras protein signal transduction GO:0046578 155 0.020
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.020
positive regulation of nucleotide metabolic process GO:0045981 230 0.020
neuromuscular process GO:0050905 15 0.020
ras protein signal transduction GO:0007265 73 0.020
regulation of syncytium formation by plasma membrane fusion GO:0060142 2 0.020
cell part morphogenesis GO:0032990 137 0.020
Fly
intracellular receptor signaling pathway GO:0030522 104 0.020
negative regulation of cell cycle GO:0045786 193 0.020
cell division GO:0051301 168 0.020
ribonucleoprotein complex biogenesis GO:0022613 116 0.020
cellular response to dna damage stimulus GO:0006974 379 0.019
regulation of transcription elongation from rna polymerase ii promoter GO:0034243 13 0.019
positive regulation of chromatin modification GO:1903310 30 0.019
epithelial cell differentiation GO:0030855 141 0.019
tube morphogenesis GO:0035239 95 0.019
cellular protein complex assembly GO:0043623 188 0.019
cellular amino acid metabolic process GO:0006520 116 0.019
regulation of synaptic vesicle transport GO:1902803 3 0.019
lipid storage GO:0019915 28 0.019
mitotic cell cycle GO:0000278 326 0.019
positive regulation of cell differentiation GO:0045597 211 0.019
regulation of cell cycle phase transition GO:1901987 126 0.019
peripheral nervous system development GO:0007422 2 0.019
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 91 0.019
vesicle organization GO:0016050 62 0.019
positive regulation of immune response GO:0050778 159 0.019
histone h3 k9 modification GO:0061647 11 0.019
response to abiotic stimulus GO:0009628 336 0.018
regulation of gluconeogenesis by regulation of transcription from rna polymerase ii promoter GO:0035947 1 0.018
translation GO:0006412 132 0.018
embryo development GO:0009790 123 0.018
protein complex disassembly GO:0043241 52 0.018
rna processing GO:0006396 255 0.018
Yeast
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.018
Fly
cell projection morphogenesis GO:0048858 129 0.018
Fly
nucleoside catabolic process GO:0009164 408 0.018
negative regulation of cell cycle phase transition GO:1901988 89 0.018
positive regulation of transcription elongation from rna polymerase ii promoter GO:0032968 10 0.018
regulation of carbohydrate biosynthetic process GO:0043255 27 0.018
stem cell differentiation GO:0048863 93 0.018
positive regulation of transport GO:0051050 336 0.018
regulation of protein localization GO:0032880 296 0.018
nucleoside monophosphate catabolic process GO:0009125 159 0.017
regulation of translation GO:0006417 89 0.017
cytokine production GO:0001816 247 0.017
apoptotic signaling pathway GO:0097190 268 0.017
ribonucleoprotein complex assembly GO:0022618 78 0.017
mitotic cell cycle phase transition GO:0044772 162 0.017
regulation of chromatin organization GO:1902275 56 0.017
positive regulation of nucleotide catabolic process GO:0030813 185 0.017
negative regulation of mrna processing GO:0050686 12 0.017
negative regulation of protein modification process GO:0031400 200 0.017
guanosine containing compound catabolic process GO:1901069 239 0.017
negative regulation of intracellular signal transduction GO:1902532 183 0.016
anterior posterior axis specification GO:0009948 2 0.016
adult behavior GO:0030534 18 0.016
regulation of small gtpase mediated signal transduction GO:0051056 156 0.016
transcription initiation from rna polymerase ii promoter GO:0006367 27 0.016
response to peptide hormone GO:0043434 61 0.016
positive regulation of gtp catabolic process GO:0033126 166 0.016
establishment of organelle localization GO:0051656 59 0.016
cell cycle checkpoint GO:0000075 117 0.016
regulation of cellular component biogenesis GO:0044087 281 0.016
positive regulation of mitotic cell cycle GO:0045931 60 0.016
gtp catabolic process GO:0006184 237 0.016
purine nucleoside triphosphate catabolic process GO:0009146 392 0.016
positive regulation of histone modification GO:0031058 29 0.016
cellular homeostasis GO:0019725 196 0.016
ion homeostasis GO:0050801 230 0.016
regulation of proteolysis GO:0030162 293 0.016
negative regulation of mitotic cell cycle GO:0045930 102 0.016
response to external biotic stimulus GO:0043207 261 0.016
negative regulation of wnt signaling pathway GO:0030178 69 0.016
guanosine containing compound metabolic process GO:1901068 244 0.016
protein targeting GO:0006605 187 0.016
positive regulation of hydrolase activity GO:0051345 331 0.016
protein dna complex subunit organization GO:0071824 80 0.015
oocyte development GO:0048599 1 0.015
response to biotic stimulus GO:0009607 276 0.015
histone exchange GO:0043486 3 0.015
regulation of intracellular transport GO:0032386 195 0.015
negative regulation of phosphorus metabolic process GO:0010563 267 0.015
regulation of meiosis GO:0040020 3 0.015
regulation of synaptic vesicle exocytosis GO:2000300 2 0.015
negative regulation of phosphate metabolic process GO:0045936 267 0.015
nucleoside triphosphate metabolic process GO:0009141 422 0.015
regulation of cytoskeleton organization GO:0051493 177 0.015
regulation of gtpase activity GO:0043087 180 0.015
positive regulation of immune system process GO:0002684 283 0.015
proteasomal protein catabolic process GO:0010498 176 0.015
posttranscriptional gene silencing by rna GO:0035194 25 0.015
regulation of anatomical structure morphogenesis GO:0022603 286 0.015
wound healing GO:0042060 115 0.015
positive regulation of mitosis GO:0045840 25 0.015
response to nutrient levels GO:0031667 81 0.015
response to organonitrogen compound GO:0010243 156 0.015
regulation of mrna processing GO:0050684 48 0.015
positive regulation of myeloid cell apoptotic process GO:0033034 2 0.015
negative regulation of transport GO:0051051 176 0.015
positive regulation of stem cell differentiation GO:2000738 29 0.014
negative regulation of mrna splicing via spliceosome GO:0048025 11 0.014
taxis GO:0042330 157 0.014
Fly
oxidation reduction process GO:0055114 396 0.014
negative regulation of translation GO:0017148 37 0.014
tissue morphogenesis GO:0048729 96 0.014
atp catabolic process GO:0006200 157 0.014
rna splicing GO:0008380 131 0.014
Yeast
ubiquitin dependent protein catabolic process GO:0006511 206 0.014
Fly
positive regulation of nucleoside metabolic process GO:0045979 186 0.014
response to fungus GO:0009620 4 0.014
regionalization GO:0003002 29 0.014
negative regulation of canonical wnt signaling pathway GO:0090090 55 0.014
regulation of nucleotide catabolic process GO:0030811 205 0.014
mitotic cell cycle checkpoint GO:0007093 68 0.014
regulation of vesicle mediated transport GO:0060627 130 0.014
organelle fusion GO:0048284 36 0.014
regulation of cell motility GO:2000145 299 0.014
positive regulation of cell cycle process GO:0090068 106 0.014
negative regulation of catalytic activity GO:0043086 335 0.014
positive regulation of leukocyte proliferation GO:0070665 48 0.014
cellular response to starvation GO:0009267 58 0.013
primary neural tube formation GO:0014020 3 0.013
positive regulation of mrna processing GO:0050685 17 0.013
response to extracellular stimulus GO:0009991 85 0.013
n terminal protein amino acid acetylation GO:0006474 10 0.013
regulation of rna splicing GO:0043484 62 0.013
modification dependent protein catabolic process GO:0019941 209 0.013
Fly
anion transport GO:0006820 161 0.013
positive regulation of cellular component biogenesis GO:0044089 158 0.013
response to wounding GO:0009611 168 0.013
ribonucleoside catabolic process GO:0042454 406 0.013
g protein coupled receptor signaling pathway GO:0007186 207 0.013
regulation of protein glycosylation GO:0060049 6 0.013
monosaccharide biosynthetic process GO:0046364 10 0.013
regulation of feeding behavior GO:0060259 3 0.013
regulation of gtp catabolic process GO:0033124 180 0.013
ossification GO:0001503 121 0.013
negative regulation of catabolic process GO:0009895 104 0.013
regulation of neural precursor cell proliferation GO:2000177 4 0.013
purine ribonucleotide catabolic process GO:0009154 404 0.013
positive regulation of gtpase activity GO:0043547 166 0.013
regulation of cellular response to stress GO:0080135 244 0.013
glycosphingolipid catabolic process GO:0046479 6 0.013
cell cell signaling GO:0007267 155 0.013
receptor metabolic process GO:0043112 81 0.013
mrna metabolic process GO:0016071 175 0.013
negative regulation of secretion by cell GO:1903531 52 0.012
morphogenesis of an epithelium GO:0002009 60 0.012
regulation of meiotic cell cycle GO:0051445 4 0.012
ion transmembrane transport GO:0034220 338 0.012
protein stabilization GO:0050821 64 0.012
regulation of homeostatic process GO:0032844 121 0.012
regulation of leukocyte activation GO:0002694 115 0.012
fatty acid metabolic process GO:0006631 115 0.012
regulation of myoblast fusion GO:1901739 1 0.012
regulation of cell morphogenesis GO:0022604 153 0.012
viral process GO:0016032 146 0.012
small molecule biosynthetic process GO:0044283 157 0.012
negative regulation of developmental process GO:0051093 247 0.012
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.012
negative regulation of hydrolase activity GO:0051346 182 0.012
lung epithelial cell differentiation GO:0060487 1 0.012
glycolipid catabolic process GO:0019377 8 0.012
oocyte differentiation GO:0009994 2 0.012
regulation of growth rate GO:0040009 1 0.012
ensheathment of neurons GO:0007272 6 0.012
regulation of wnt signaling pathway GO:0030111 123 0.012
regulation of exocytosis GO:0017157 46 0.012
regulation of mrna metabolic process GO:1903311 53 0.012
positive regulation of leukocyte activation GO:0002696 80 0.012
negative regulation of cellular amine metabolic process GO:0033239 3 0.012
positive regulation of programmed cell death GO:0043068 249 0.012
positive regulation of developmental process GO:0051094 314 0.012
negative regulation of cellular component organization GO:0051129 235 0.012
cellular chemical homeostasis GO:0055082 180 0.012
response to starvation GO:0042594 59 0.012
protein targeting to nucleus GO:0044744 104 0.012
lipid transport GO:0006869 90 0.012
actin filament organization GO:0007015 128 0.012
protein maturation GO:0051604 233 0.012
mrna splicing via spliceosome GO:0000398 89 0.012
ribonucleoside monophosphate metabolic process GO:0009161 187 0.012
cell activation GO:0001775 213 0.012
reactive oxygen species metabolic process GO:0072593 75 0.012
regulation of secretion by cell GO:1903530 177 0.012
establishment or maintenance of apical basal cell polarity GO:0035088 2 0.012
cation homeostasis GO:0055080 189 0.011
negative regulation of rna splicing GO:0033119 15 0.011
histone methylation GO:0016571 60 0.011
Yeast
negative regulation of cell death GO:0060548 345 0.011
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 89 0.011
receptor mediated endocytosis GO:0006898 84 0.011
regulation of neurotransmitter secretion GO:0046928 3 0.011
positive regulation of mononuclear cell proliferation GO:0032946 47 0.011
protein dna complex assembly GO:0065004 64 0.011
negative regulation of organelle organization GO:0010639 126 0.011
rna splicing via transesterification reactions GO:0000375 90 0.011
central nervous system development GO:0007417 123 0.011
nuclear import GO:0051170 106 0.011
protein import into nucleus GO:0006606 104 0.011
organ formation GO:0048645 3 0.011
regulation of ras gtpase activity GO:0032318 128 0.011
cation transport GO:0006812 331 0.011
positive regulation of growth GO:0045927 58 0.011
negative regulation of cell cycle process GO:0010948 121 0.011
morphogenesis of a polarized epithelium GO:0001738 3 0.011
positive regulation of ras gtpase activity GO:0032320 117 0.011
regulation of protein ubiquitination GO:0031396 95 0.011
regulation of mitotic cell cycle phase transition GO:1901990 118 0.011
mitochondrial translation GO:0032543 17 0.011
regulation of actin cytoskeleton organization GO:0032956 116 0.011
mrna catabolic process GO:0006402 56 0.011
compound eye development GO:0048749 1 0.011
positive regulation of lymphocyte proliferation GO:0050671 46 0.011
posttranscriptional gene silencing GO:0016441 25 0.011
organophosphate catabolic process GO:0046434 430 0.011
regulation of cell differentiation GO:0045595 393 0.010
mitotic nuclear division GO:0007067 119 0.010
establishment of nucleus localization GO:0040023 1 0.010
response to decreased oxygen levels GO:0036293 96 0.010
protein k33 linked ubiquitination GO:1990390 1 0.010
regulation of proteasomal protein catabolic process GO:0061136 87 0.010
gene silencing by rna GO:0031047 26 0.010
nucleosome organization GO:0034728 66 0.010
regulation of nervous system development GO:0051960 88 0.010
leukocyte activation GO:0045321 164 0.010
response to axon injury GO:0048678 1 0.010
organophosphate biosynthetic process GO:0090407 163 0.010
distal tubule development GO:0072017 4 0.010
protein polyubiquitination GO:0000209 110 0.010
memory GO:0007613 3 0.010
rhythmic behavior GO:0007622 2 0.010
protein alkylation GO:0008213 74 0.010
Yeast
regulation of cell migration GO:0030334 289 0.010
forebrain development GO:0030900 26 0.010
regulation of cellular component movement GO:0051270 334 0.010
membrane fusion GO:0061025 43 0.010
protein adp ribosylation GO:0006471 9 0.010
negative regulation of multicellular organismal process GO:0051241 317 0.010

USP22 disease predictions

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 295 0.359
lysosomal storage disease DOID:3211 47 0.351
inherited metabolic disorder DOID:655 242 0.351
cerebral degeneration DOID:1443 16 0.230
central nervous system disease DOID:331 186 0.230
brain disease DOID:936 73 0.230
nervous system disease DOID:863 431 0.230
lipid storage disease DOID:9455 28 0.076
sphingolipidosis DOID:1927 14 0.023
disease of cellular proliferation DOID:14566 174 0.017
sensory system disease DOID:0050155 203 0.017
eye and adnexa disease DOID:1492 150 0.015
eye disease DOID:5614 149 0.015
musculoskeletal system disease DOID:17 223 0.012
cancer DOID:162 167 0.011
organ system cancer DOID:0050686 164 0.011