IMP

Process View

Homo sapiens

16 genes annotated in human

Multi-species View

histone deubiquitination

GO:0016578

The modification of histones by removal of ubiquitin groups.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "histone deubiquitination"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "histone deubiquitination" (in gray)

Name	Description	Probability	Func Analog Organism
TRRAP	transformation/transcription domain-associated protein	1.000
KAT2A	K(lysine) acetyltransferase 2A	1.000
TAF4	TAF4 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 135kDa	0.992
USP22	ubiquitin specific peptidase 22	0.983
FAM175A	family with sequence similarity 175, member A	0.983
TADA3	transcriptional adaptor 3	0.849
BAP1	BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)	0.836
ATXN7	ataxin 7	0.734
TAF6	TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80kDa	0.707
HERC2	hect domain and RLD 2	0.548
MDM4	Mdm4 p53 binding protein homolog (mouse)	0.443
BRE	brain and reproductive organ-expressed (TNFRSF1A modulator)	0.245
PICK1	protein interacting with PRKCA 1	0.163
EP300	E1A binding protein p300	0.158
TAF10	TAF10 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 30kDa	0.157
SETD7	SET domain containing (lysine methyltransferase) 7	0.141
TADA2A	transcriptional adaptor 2A	0.135
ASXL1	additional sex combs like 1 (Drosophila)	0.129
FUBP1	far upstream element (FUSE) binding protein 1	0.107
MED12	mediator complex subunit 12	0.099
SUPT3H	suppressor of Ty 3 homolog (S. cerevisiae)	0.087
TAF6L	TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa	0.075
SECISBP2	SECIS binding protein 2	0.071
HEXA	hexosaminidase A (alpha polypeptide)	0.064
KPNA3	karyopherin alpha 3 (importin alpha 4)	0.058
ATXN7L3	ataxin 7-like 3	0.056
RNF220	ring finger protein 220	0.047
YLPM1	YLP motif containing 1	0.044
INO80	INO80 homolog (S. cerevisiae)	0.042
EP400	E1A binding protein p400	0.039
FAM175B	family with sequence similarity 175, member B	0.039
MED24	mediator complex subunit 24	0.038
USP6	ubiquitin specific peptidase 6 (Tre-2 oncogene)	0.038
USP44	ubiquitin specific peptidase 44	0.037	Human
HIST2H2AC	histone cluster 2, H2ac	0.036
FAM193A	family with sequence similarity 193, member A	0.034
TADA1	transcriptional adaptor 1	0.033
YY1	YY1 transcription factor	0.032
HUWE1	HECT, UBA and WWE domain containing 1	0.032
MRPL10	mitochondrial ribosomal protein L10	0.031
USP49	ubiquitin specific peptidase 49	0.029
PSMA4	proteasome (prosome, macropain) subunit, alpha type, 4	0.028
SNAPC5	small nuclear RNA activating complex, polypeptide 5, 19kDa	0.027
CCDC101	coiled-coil domain containing 101	0.026
AKT1	v-akt murine thymoma viral oncogene homolog 1	0.026
TBP	TATA box binding protein	0.025
BRD1	bromodomain containing 1	0.023
ANKRD52	ankyrin repeat domain 52	0.022
GTF2I	general transcription factor IIi	0.022
FOXK2	forkhead box K2	0.022
PAPD7	PAP associated domain containing 7	0.021
ACACA	acetyl-CoA carboxylase alpha	0.021
TAF5L	TAF5-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa	0.020
HCFC1	host cell factor C1 (VP16-accessory protein)	0.020
PPP6R3	protein phosphatase 6, regulatory subunit 3	0.019
BRAP	BRCA1 associated protein	0.017
PSMD6	proteasome (prosome, macropain) 26S subunit, non-ATPase, 6	0.017
PSMC2	proteasome (prosome, macropain) 26S subunit, ATPase, 2	0.017
RBBP8	retinoblastoma binding protein 8	0.016
RAD23B	RAD23 homolog B (S. cerevisiae)	0.016
UBE2O	ubiquitin-conjugating enzyme E2O	0.016
PSMC6	proteasome (prosome, macropain) 26S subunit, ATPase, 6	0.015
SCAF4	SR-related CTD-associated factor 4	0.015
MCM3AP	minichromosome maintenance complex component 3 associated protein	0.014
RINT1	RAD50 interactor 1	0.014
KDM1B	lysine (K)-specific demethylase 1B	0.013
UIMC1	ubiquitin interaction motif containing 1	0.013
UTP18	UTP18, small subunit (SSU) processome component, homolog (yeast)	0.013
NCOA6	nuclear receptor coactivator 6	0.013
TADA2B	transcriptional adaptor 2B	0.012
VPS72	vacuolar protein sorting 72 homolog (S. cerevisiae)	0.012
USP11	ubiquitin specific peptidase 11	0.011
TAF12	TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 20kDa	0.011
USP14	ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase)	0.011
MTOR	mechanistic target of rapamycin (serine/threonine kinase)	0.011
C20orf20	chromosome 20 open reading frame 20	0.010
ACTR5	ARP5 actin-related protein 5 homolog (yeast)	0.010
NFRKB	nuclear factor related to kappaB binding protein	0.010
ZNF692	zinc finger protein 692	0.010
TXNL1	thioredoxin-like 1	0.010