IMP

Process View

Homo sapiens

28 genes annotated in human

lipid storage

GO:0019915

The accumulation and maintenance in cells or tissues of lipids, compounds soluble in organic solvents but insoluble or sparingly soluble in aqueous solvents. Lipid reserves can be accumulated during early developmental stages for mobilization and utilization at later stages of development.

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "lipid storage"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "lipid storage" (in gray)

Name	Description	Probability	Func Analog Organism
ITGB1	integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)	0.867
INSR	insulin receptor	0.672	Worm
TMED10	transmembrane emp24-like trafficking protein 10 (yeast)	0.588
PDIA3	protein disulfide isomerase family A, member 3	0.549
FHL2	four and a half LIM domains 2	0.370
RARA	retinoic acid receptor, alpha	0.353
PBX1	pre-B-cell leukemia homeobox 1	0.346	Worm
SIRT1	sirtuin 1	0.344
PPARGC1A	peroxisome proliferator-activated receptor gamma, coactivator 1 alpha	0.296
EIF4A1	eukaryotic translation initiation factor 4A1	0.217	Worm
UBE2D2	ubiquitin-conjugating enzyme E2D 2 (UBC4/5 homolog, yeast)	0.211
UBE2I	ubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast)	0.205
NCOA1	nuclear receptor coactivator 1	0.196
BTRC	beta-transducin repeat containing	0.160
PTPN1	protein tyrosine phosphatase, non-receptor type 1	0.154
IRAK2	interleukin-1 receptor-associated kinase 2	0.147
YWHAB	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide	0.127
RXRA	retinoid X receptor, alpha	0.119	Worm
ARIH2	ariadne homolog 2 (Drosophila)	0.115
ALDOA	aldolase A, fructose-bisphosphate	0.114
HIPK2	homeodomain interacting protein kinase 2	0.114
OGT	O-linked N-acetylglucosamine (GlcNAc) transferase (UDP-N-acetylglucosamine:polypeptide-N-acetylglucosaminyl transferase)	0.106	Worm
NFKB2	nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)	0.104
COPE	coatomer protein complex, subunit epsilon	0.100
NFKBIA	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha	0.099
HDAC4	histone deacetylase 4	0.098
COPB1	coatomer protein complex, subunit beta 1	0.097
PGK1	phosphoglycerate kinase 1	0.095
ESR1	estrogen receptor 1	0.094
TNIP2	TNFAIP3 interacting protein 2	0.093
CANX	calnexin	0.092
PRKAB2	protein kinase, AMP-activated, beta 2 non-catalytic subunit	0.090
IL1R1	interleukin 1 receptor, type I	0.089
GHR	growth hormone receptor	0.082
DDX3X	DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, X-linked	0.078
SCFD1	sec1 family domain containing 1	0.075
RNF5	ring finger protein 5	0.069
CREB1	cAMP responsive element binding protein 1	0.068
IKBKB	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta	0.067
IRS1	insulin receptor substrate 1	0.060
EIF4G1	eukaryotic translation initiation factor 4 gamma, 1	0.059
NBN	nibrin	0.055
LDHA	lactate dehydrogenase A	0.055
NFKB1	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1	0.055
CTBP1	C-terminal binding protein 1	0.054
EIF6	eukaryotic translation initiation factor 6	0.053
COPZ1	coatomer protein complex, subunit zeta 1	0.050
FLNA	filamin A, alpha	0.049
FN1	fibronectin 1	0.048
KAT5	K(lysine) acetyltransferase 5	0.048
AKT1	v-akt murine thymoma viral oncogene homolog 1	0.047	Fly
ILK	integrin-linked kinase	0.046
UBA5	ubiquitin-like modifier activating enzyme 5	0.046
CTNNBL1	catenin, beta like 1	0.044
SQLE	squalene epoxidase	0.044
GAPDH	glyceraldehyde-3-phosphate dehydrogenase	0.044	Worm
ARIH1	ariadne homolog, ubiquitin-conjugating enzyme E2 binding protein, 1 (Drosophila)	0.044
CRP	C-reactive protein, pentraxin-related	0.043
INSIG1	insulin induced gene 1	0.042
RAB1A	RAB1A, member RAS oncogene family	0.042
UBE2D3	ubiquitin-conjugating enzyme E2D 3 (UBC4/5 homolog, yeast)	0.041
SRSF7	serine/arginine-rich splicing factor 7	0.041
TLN1	talin 1	0.041
ITGB5	integrin, beta 5	0.041
CTBP2	C-terminal binding protein 2	0.040
CAT	catalase	0.040
ENO1	enolase 1, (alpha)	0.039
MEIS1	Meis homeobox 1	0.039	Worm
WDYHV1	WDYHV motif containing 1	0.038
APOE	apolipoprotein E	0.038
UQCRB	ubiquinol-cytochrome c reductase binding protein	0.037
GPI	glucose-6-phosphate isomerase	0.037
HNRNPH2	heterogeneous nuclear ribonucleoprotein H2 (H')	0.036
CSNK2B	casein kinase 2, beta polypeptide	0.035
RAD50	RAD50 homolog (S. cerevisiae)	0.034
SRSF10	serine/arginine-rich splicing factor 10	0.032
UBE2V1	ubiquitin-conjugating enzyme E2 variant 1	0.030
RBBP8	retinoblastoma binding protein 8	0.030
IL1RAP	interleukin 1 receptor accessory protein	0.030
PXN	paxillin	0.030
HP	haptoglobin	0.030
CTSD	cathepsin D	0.030
TNFRSF1A	tumor necrosis factor receptor superfamily, member 1A	0.029
SPG20	spastic paraplegia 20 (Troyer syndrome)	0.029
ARHGDIB	Rho GDP dissociation inhibitor (GDI) beta	0.029
HAP1	huntingtin-associated protein 1	0.029
SEC61A1	Sec61 alpha 1 subunit (S. cerevisiae)	0.028
FGB	fibrinogen beta chain	0.028
MEIS2	Meis homeobox 2	0.028	Worm
SLC25A3	solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3	0.028
ENG	endoglin	0.027
DHCR7	7-dehydrocholesterol reductase	0.027
MED25	mediator complex subunit 25	0.027
CUL1	cullin 1	0.027
KLHL12	kelch-like 12 (Drosophila)	0.027
ATP5O	ATP synthase, H+ transporting, mitochondrial F1 complex, O subunit	0.026
MTOR	mechanistic target of rapamycin (serine/threonine kinase)	0.026
BCAR1	breast cancer anti-estrogen resistance 1	0.026
EEA1	early endosome antigen 1	0.026
ZNF746	zinc finger protein 746	0.026
LMAN1	lectin, mannose-binding, 1	0.025
ATM	ataxia telangiectasia mutated	0.025
COPG	coatomer protein complex, subunit gamma	0.025
ACACA	acetyl-CoA carboxylase alpha	0.025
ATRX	alpha thalassemia/mental retardation syndrome X-linked	0.025
SRSF5	serine/arginine-rich splicing factor 5	0.025
HADHB	hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), beta subunit	0.025
EIF3A	eukaryotic translation initiation factor 3, subunit A	0.024
GRB10	growth factor receptor-bound protein 10	0.024
ATP5L	ATP synthase, H+ transporting, mitochondrial Fo complex, subunit G	0.023
FUS	fused in sarcoma	0.023
LDLR	low density lipoprotein receptor	0.023
IDH1	isocitrate dehydrogenase 1 (NADP+), soluble	0.022
TPI1	triosephosphate isomerase 1	0.022
RPS6	ribosomal protein S6	0.021
SDHB	succinate dehydrogenase complex, subunit B, iron sulfur (Ip)	0.021
AR	androgen receptor	0.021
FCN2	ficolin (collagen/fibrinogen domain containing lectin) 2 (hucolin)	0.021	Human
SNW1	SNW domain containing 1	0.021
TIA1	TIA1 cytotoxic granule-associated RNA binding protein	0.021
MED15	mediator complex subunit 15	0.020
ACSL3	acyl-CoA synthetase long-chain family member 3	0.020
NEU1	sialidase 1 (lysosomal sialidase)	0.020
NFKBIB	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta	0.020	Human
TGFB1	transforming growth factor, beta 1	0.020
TNFRSF1B	tumor necrosis factor receptor superfamily, member 1B	0.020
RUNX1	runt-related transcription factor 1	0.019
PTPN11	protein tyrosine phosphatase, non-receptor type 11	0.019
USP22	ubiquitin specific peptidase 22	0.019
HMGCS1	3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)	0.019
ELAVL1	ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R)	0.019
PKM2	pyruvate kinase, muscle	0.019
ATP5C1	ATP synthase, H+ transporting, mitochondrial F1 complex, gamma polypeptide 1	0.018
RPN2	ribophorin II	0.018
CD2AP	CD2-associated protein	0.018
CALU	calumenin	0.018
CFH	complement factor H	0.018
MAPKAPK2	mitogen-activated protein kinase-activated protein kinase 2	0.018
LSS	lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase)	0.018
SKP2	S-phase kinase-associated protein 2 (p45)	0.018
LCAT	lecithin-cholesterol acyltransferase	0.018
WBP11	WW domain binding protein 11	0.018
RPL18A	ribosomal protein L18a	0.018
ARFGEF1	ADP-ribosylation factor guanine nucleotide-exchange factor 1(brefeldin A-inhibited)	0.018
VHL	von Hippel-Lindau tumor suppressor	0.018
EIF3D	eukaryotic translation initiation factor 3, subunit D	0.018
SC4MOL	sterol-C4-methyl oxidase-like	0.017
KIAA1377	KIAA1377	0.017
PRR5	proline rich 5 (renal)	0.017
APOC1	apolipoprotein C-I	0.017
EGFR	epidermal growth factor receptor	0.017
EIF3K	eukaryotic translation initiation factor 3, subunit K	0.017
ARPC1B	actin related protein 2/3 complex, subunit 1B, 41kDa	0.017
HSPA5	heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)	0.017	Worm
CDC37	cell division cycle 37 homolog (S. cerevisiae)	0.017
IL1RN	interleukin 1 receptor antagonist	0.016	Human
FANCD2	Fanconi anemia, complementation group D2	0.016
IRF2	interferon regulatory factor 2	0.016
NEDD4	neural precursor cell expressed, developmentally down-regulated 4	0.016
LAMP1	lysosomal-associated membrane protein 1	0.016
NCOA3	nuclear receptor coactivator 3	0.016
SSR1	signal sequence receptor, alpha	0.016
PRKAB1	protein kinase, AMP-activated, beta 1 non-catalytic subunit	0.016
SMPD1	sphingomyelin phosphodiesterase 1, acid lysosomal	0.016
IRS2	insulin receptor substrate 2	0.016
EZR	ezrin	0.016
AP3B1	adaptor-related protein complex 3, beta 1 subunit	0.016	Worm
PML	promyelocytic leukemia	0.015
LYN	v-yes-1 Yamaguchi sarcoma viral related oncogene homolog	0.015
RPL11	ribosomal protein L11	0.015
SREBF1	sterol regulatory element binding transcription factor 1	0.015	Human Worm
CSNK2A1	casein kinase 2, alpha 1 polypeptide	0.015
COPG2	coatomer protein complex, subunit gamma 2	0.015
RPL36AL	ribosomal protein L36a-like	0.015
ANKFY1	ankyrin repeat and FYVE domain containing 1	0.014
TGM2	transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase)	0.014
HOXA9	homeobox A9	0.014
BRD8	bromodomain containing 8	0.014
DECR1	2,4-dienoyl CoA reductase 1, mitochondrial	0.014
STT3A	STT3, subunit of the oligosaccharyltransferase complex, homolog A (S. cerevisiae)	0.014
HMGCR	3-hydroxy-3-methylglutaryl-CoA reductase	0.014	Worm
NR0B2	nuclear receptor subfamily 0, group B, member 2	0.014
PPP3R1	protein phosphatase 3, regulatory subunit B, alpha	0.014
CDKN1A	cyclin-dependent kinase inhibitor 1A (p21, Cip1)	0.014
GLE1	GLE1 RNA export mediator homolog (yeast)	0.014
ATP6V0D1	ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d1	0.014
PRTFDC1	phosphoribosyl transferase domain containing 1	0.014
EIF4E	eukaryotic translation initiation factor 4E	0.014	Worm
MGEA5	meningioma expressed antigen 5 (hyaluronidase)	0.014	Worm
KIAA0174	KIAA0174	0.014
RPS16	ribosomal protein S16	0.014
IDH3B	isocitrate dehydrogenase 3 (NAD+) beta	0.014
TKT	transketolase	0.013
JAK2	Janus kinase 2	0.013
NDUFS2	NADH dehydrogenase (ubiquinone) Fe-S protein 2, 49kDa (NADH-coenzyme Q reductase)	0.013
SPTBN1	spectrin, beta, non-erythrocytic 1	0.013
WDR48	WD repeat domain 48	0.013
NCL	nucleolin	0.013
REL	v-rel reticuloendotheliosis viral oncogene homolog (avian)	0.013
SMURF1	SMAD specific E3 ubiquitin protein ligase 1	0.013
PIAS3	protein inhibitor of activated STAT, 3	0.013
CHD9	chromodomain helicase DNA binding protein 9	0.013
GSTO1	glutathione S-transferase omega 1	0.013
RBCK1	RanBP-type and C3HC4-type zinc finger containing 1	0.013
RPL37	ribosomal protein L37	0.013
EWSR1	Ewing sarcoma breakpoint region 1	0.013
ITGAV	integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51)	0.013
HGS	hepatocyte growth factor-regulated tyrosine kinase substrate	0.012
GLB1	galactosidase, beta 1	0.012
RPL8	ribosomal protein L8	0.012
APOC3	apolipoprotein C-III	0.012
NDUFV2	NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa	0.012
VCAM1	vascular cell adhesion molecule 1	0.012
UBE2M	ubiquitin-conjugating enzyme E2M (UBC12 homolog, yeast)	0.012
RHOA	ras homolog gene family, member A	0.012
COG1	component of oligomeric golgi complex 1	0.012
TAF1D	TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa	0.012
CNOT1	CCR4-NOT transcription complex, subunit 1	0.012
NCF1	neutrophil cytosolic factor 1	0.012
RELB	v-rel reticuloendotheliosis viral oncogene homolog B	0.012
MDH1	malate dehydrogenase 1, NAD (soluble)	0.012
PPP4C	protein phosphatase 4, catalytic subunit	0.012
SRPK2	SRSF protein kinase 2	0.012
PPIB	peptidylprolyl isomerase B (cyclophilin B)	0.012
CUL5	cullin 5	0.012
STAT5A	signal transducer and activator of transcription 5A	0.012	Mouse
ATP6V1F	ATPase, H+ transporting, lysosomal 14kDa, V1 subunit F	0.012
COX4I1	cytochrome c oxidase subunit IV isoform 1	0.012
TOMM22	translocase of outer mitochondrial membrane 22 homolog (yeast)	0.012
IRAK1	interleukin-1 receptor-associated kinase 1	0.012
PDIA6	protein disulfide isomerase family A, member 6	0.012
SENP1	SUMO1/sentrin specific peptidase 1	0.012
CYC1	cytochrome c-1	0.012
PGM3	phosphoglucomutase 3	0.012
TSC22D4	TSC22 domain family, member 4	0.012
RELA	v-rel reticuloendotheliosis viral oncogene homolog A (avian)	0.011
NDUFB8	NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 8, 19kDa	0.011
ARHGEF7	Rho guanine nucleotide exchange factor (GEF) 7	0.011
CYP51A1	cytochrome P450, family 51, subfamily A, polypeptide 1	0.011
CD63	CD63 molecule	0.011
REV3L	REV3-like, catalytic subunit of DNA polymerase zeta (yeast)	0.011
TCERG1	transcription elongation regulator 1	0.011
RANGAP1	Ran GTPase activating protein 1	0.011
WDR77	WD repeat domain 77	0.011
MEF2C	myocyte enhancer factor 2C	0.011	Fly
MYH9	myosin, heavy chain 9, non-muscle	0.011
PTP4A2	protein tyrosine phosphatase type IVA, member 2	0.011
HNRNPD	heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa)	0.011
NDUFA4	NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4, 9kDa	0.011
IDI1	isopentenyl-diphosphate delta isomerase 1	0.011
IL1B	interleukin 1, beta	0.011
PGAM1	phosphoglycerate mutase 1 (brain)	0.011
HNRNPA2B1	heterogeneous nuclear ribonucleoprotein A2/B1	0.011
STAP2	signal transducing adaptor family member 2	0.011
TNFAIP2	tumor necrosis factor, alpha-induced protein 2	0.011
APOA2	apolipoprotein A-II	0.011
COG7	component of oligomeric golgi complex 7	0.011
CAP1	CAP, adenylate cyclase-associated protein 1 (yeast)	0.011
ZFP36	zinc finger protein 36, C3H type, homolog (mouse)	0.011
RTN4IP1	reticulon 4 interacting protein 1	0.011
DLD	dihydrolipoamide dehydrogenase	0.011
DHX33	DEAH (Asp-Glu-Ala-His) box polypeptide 33	0.011
MYC	v-myc myelocytomatosis viral oncogene homolog (avian)	0.011
ATP5G3	ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C3 (subunit 9)	0.011
RPS3A	ribosomal protein S3A	0.011
DHCR24	24-dehydrocholesterol reductase	0.011
SH3RF1	SH3 domain containing ring finger 1	0.011
COX6C	cytochrome c oxidase subunit VIc	0.011
MAP2K3	mitogen-activated protein kinase kinase 3	0.011
TMED9	transmembrane emp24 protein transport domain containing 9	0.011
PICALM	phosphatidylinositol binding clathrin assembly protein	0.011
ITGA4	integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)	0.010	Human
PDK1	pyruvate dehydrogenase kinase, isozyme 1	0.010
MKI67	antigen identified by monoclonal antibody Ki-67	0.010
VDR	vitamin D (1,25- dihydroxyvitamin D3) receptor	0.010	Human
SRSF6	serine/arginine-rich splicing factor 6	0.010
ZFC3H1	zinc finger, C3H1-type containing	0.010
EIF3I	eukaryotic translation initiation factor 3, subunit I	0.010
DEGS1	degenerative spermatocyte homolog 1, lipid desaturase (Drosophila)	0.010
CAND1	cullin-associated and neddylation-dissociated 1	0.010
POU5F1	POU class 5 homeobox 1	0.010
RPL17	ribosomal protein L17	0.010
FBXO33	F-box protein 33	0.010
UBE2D1	ubiquitin-conjugating enzyme E2D 1 (UBC4/5 homolog, yeast)	0.010
APOC2	apolipoprotein C-II	0.010
HR	hairless homolog (mouse)	0.010
GOLGA5	golgin A5	0.010
STAT5B	signal transducer and activator of transcription 5B	0.010	Mouse
SEPT2	septin 2	0.010
ITGA1	integrin, alpha 1	0.010
EDF1	endothelial differentiation-related factor 1	0.010