IMP

Process View

Homo sapiens

10 genes annotated in human

positive regulation of transcription elongation from rna polymerase ii promoter

Any process that activates or increases the frequency, rate or extent of transcription elongation, the extension of an RNA molecule after transcription initiation and promoter clearance by the addition of ribonucleotides, catalyzed by RNA polymerase II.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "positive regulation of transcription elongation from rna polymerase ii promoter"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "positive regulation of transcription elongation from rna polymerase ii promoter" (in gray)

Name	Description	Probability	Func Analog Organism
LEO1	Leo1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)	1.000
CTR9	Ctr9, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)	0.999
RTF1	Rtf1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)	0.999
EP300	E1A binding protein p300	0.998
POLR2A	polymerase (RNA) II (DNA directed) polypeptide A, 220kDa	0.970
PAF1	Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae)	0.961
AFF4	AF4/FMR2 family, member 4	0.933
CREBBP	CREB binding protein	0.919
HDAC4	histone deacetylase 4	0.914
MLL	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila)	0.772	Fly
YWHAQ	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide	0.680
CNOT2	CCR4-NOT transcription complex, subunit 2	0.589
CDC73	cell division cycle 73, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)	0.581
TCEA1	transcription elongation factor A (SII), 1	0.533	Yeast
YWHAE	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide	0.525
SMURF1	SMAD specific E3 ubiquitin protein ligase 1	0.485
SMAD3	SMAD family member 3	0.468
WDR61	WD repeat domain 61	0.438
SNF8	SNF8, ESCRT-II complex subunit, homolog (S. cerevisiae)	0.436
TRRAP	transformation/transcription domain-associated protein	0.429
PSMD2	proteasome (prosome, macropain) 26S subunit, non-ATPase, 2	0.427
HIF1A	hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	0.409
CNOT8	CCR4-NOT transcription complex, subunit 8	0.394
CNOT3	CCR4-NOT transcription complex, subunit 3	0.376	Yeast
PSMD4	proteasome (prosome, macropain) 26S subunit, non-ATPase, 4	0.376
RELA	v-rel reticuloendotheliosis viral oncogene homolog A (avian)	0.374
CNOT6	CCR4-NOT transcription complex, subunit 6	0.346	Yeast
CCNT1	cyclin T1	0.344
SMAD2	SMAD family member 2	0.341
RAF1	v-raf-1 murine leukemia viral oncogene homolog 1	0.281
NCOA3	nuclear receptor coactivator 3	0.275
CNOT1	CCR4-NOT transcription complex, subunit 1	0.211	Yeast
PSMD10	proteasome (prosome, macropain) 26S subunit, non-ATPase, 10	0.174
YWHAB	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide	0.165
HIPK2	homeodomain interacting protein kinase 2	0.142
MED26	mediator complex subunit 26	0.125
PSMC1	proteasome (prosome, macropain) 26S subunit, ATPase, 1	0.120
NCOA1	nuclear receptor coactivator 1	0.116
SUPT5H	suppressor of Ty 5 homolog (S. cerevisiae)	0.109	Yeast Zebrafish
CDK9	cyclin-dependent kinase 9	0.105
YWHAH	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide	0.095
CHD8	chromodomain helicase DNA binding protein 8	0.095
NCOA6	nuclear receptor coactivator 6	0.078
MLLT1	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 1	0.076
EAF1	ELL associated factor 1	0.075
YWHAG	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide	0.068
TP53	tumor protein p53	0.068
KDM2A	lysine (K)-specific demethylase 2A	0.066
WDR5	WD repeat domain 5	0.066
PSMC2	proteasome (prosome, macropain) 26S subunit, ATPase, 2	0.066
CREB1	cAMP responsive element binding protein 1	0.064
DYRK1A	dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A	0.062
ARID1A	AT rich interactive domain 1A (SWI-like)	0.060
TAF4	TAF4 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 135kDa	0.059
YWHAZ	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide	0.059
HNRNPF	heterogeneous nuclear ribonucleoprotein F	0.057
MYST3	MYST histone acetyltransferase (monocytic leukemia) 3	0.052
CNOT7	CCR4-NOT transcription complex, subunit 7	0.046
MED15	mediator complex subunit 15	0.046
XRCC5	X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)	0.045
MEF2A	myocyte enhancer factor 2A	0.044	Fly
CABIN1	calcineurin binding protein 1	0.042
CDAN1	congenital dyserythropoietic anemia, type I	0.042
MED12	mediator complex subunit 12	0.041
AFF1	AF4/FMR2 family, member 1	0.039
HABP4	hyaluronan binding protein 4	0.037
BTG2	BTG family, member 2	0.036
AR	androgen receptor	0.034
MEF2C	myocyte enhancer factor 2C	0.033	Fly
RUNX1	runt-related transcription factor 1	0.032
PSMD7	proteasome (prosome, macropain) 26S subunit, non-ATPase, 7	0.032
SIRT1	sirtuin 1	0.032
ATG14	ATG14 autophagy related 14 homolog (S. cerevisiae)	0.032
MMS22L	MMS22-like, DNA repair protein	0.031
PSMD6	proteasome (prosome, macropain) 26S subunit, non-ATPase, 6	0.029
CTNNB1	catenin (cadherin-associated protein), beta 1, 88kDa	0.029
PSMD9	proteasome (prosome, macropain) 26S subunit, non-ATPase, 9	0.029
NCOR1	nuclear receptor corepressor 1	0.028
PSMC3	proteasome (prosome, macropain) 26S subunit, ATPase, 3	0.027
XRCC6	X-ray repair complementing defective repair in Chinese hamster cells 6	0.026
ATXN7	ataxin 7	0.025
PPP2R5C	protein phosphatase 2, regulatory subunit B', gamma	0.024
TLK1	tousled-like kinase 1	0.024
PDPK1	3-phosphoinositide dependent protein kinase-1	0.023
TRAF4	TNF receptor-associated factor 4	0.023
NCOA2	nuclear receptor coactivator 2	0.022
ZNF512B	zinc finger protein 512B	0.021
SIN3A	SIN3 homolog A, transcription regulator (yeast)	0.020
KAT2B	K(lysine) acetyltransferase 2B	0.019	Yeast
TADA2A	transcriptional adaptor 2A	0.019
HDAC9	histone deacetylase 9	0.019
USP22	ubiquitin specific peptidase 22	0.018
STAM2	signal transducing adaptor molecule (SH3 domain and ITAM motif) 2	0.016
CDK2	cyclin-dependent kinase 2	0.016
MARK3	MAP/microtubule affinity-regulating kinase 3	0.016
SUPT6H	suppressor of Ty 6 homolog (S. cerevisiae)	0.016
HCFC1	host cell factor C1 (VP16-accessory protein)	0.016
CHD4	chromodomain helicase DNA binding protein 4	0.015
YY1	YY1 transcription factor	0.015
TNRC6B	trinucleotide repeat containing 6B	0.015
SP1	Sp1 transcription factor	0.015
USP14	ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase)	0.015
SMAD1	SMAD family member 1	0.015
NR3C1	nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)	0.014
STRN4	striatin, calmodulin binding protein 4	0.014
CPEB4	cytoplasmic polyadenylation element binding protein 4	0.013
UVRAG	UV radiation resistance associated gene	0.012
TGFBR2	transforming growth factor, beta receptor II (70/80kDa)	0.012
PSMC4	proteasome (prosome, macropain) 26S subunit, ATPase, 4	0.011
TCF4	transcription factor 4	0.010