IMP

Process View

Homo sapiens

17 genes annotated in human

mitochondrial translation

The chemical reactions and pathways resulting in the formation of a protein in a mitochondrion. This is a ribosome-mediated process in which the information in messenger RNA (mRNA) is used to specify the sequence of amino acids in the protein; the mitochondrion has its own ribosomes and transfer RNAs, and uses a genetic code that differs from the nuclear code.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "mitochondrial translation"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "mitochondrial translation" (in gray)

Name	Description	Probability	Func Analog Organism
ICT1	immature colon carcinoma transcript 1	0.991
IARS	isoleucyl-tRNA synthetase	0.604
ASNS	asparagine synthetase (glutamine-hydrolyzing)	0.221
MRPS27	mitochondrial ribosomal protein S27	0.196
CARS	cysteinyl-tRNA synthetase	0.170
MRPL32	mitochondrial ribosomal protein L32	0.146
MRPL1	mitochondrial ribosomal protein L1	0.114
MRPS9	mitochondrial ribosomal protein S9	0.111
MRPL46	mitochondrial ribosomal protein L46	0.085
MRPL19	mitochondrial ribosomal protein L19	0.077
MRPS15	mitochondrial ribosomal protein S15	0.066
TRIM63	tripartite motif containing 63	0.060
TRIM55	tripartite motif containing 55	0.060
MRRF	mitochondrial ribosome recycling factor	0.057
PNPT1	polyribonucleotide nucleotidyltransferase 1	0.056
RTN4IP1	reticulon 4 interacting protein 1	0.052
TAB1	TGF-beta activated kinase 1/MAP3K7 binding protein 1	0.049
MRPL50	mitochondrial ribosomal protein L50	0.047
MRPS26	mitochondrial ribosomal protein S26	0.045
MRPL30	mitochondrial ribosomal protein L30	0.045
PPID	peptidylprolyl isomerase D	0.040
LRPPRC	leucine-rich PPR-motif containing	0.037
RNMTL1	RNA methyltransferase like 1	0.034
MRPL43	mitochondrial ribosomal protein L43	0.034
FASTKD2	FAST kinase domains 2	0.033
LIAS	lipoic acid synthetase	0.033
GEMIN5	gem (nuclear organelle) associated protein 5	0.032
METTL17	methyltransferase like 17	0.030
LARS2	leucyl-tRNA synthetase 2, mitochondrial	0.030
DDX28	DEAD (Asp-Glu-Ala-Asp) box polypeptide 28	0.028
METTL2A	methyltransferase like 2A	0.028
TSFM	Ts translation elongation factor, mitochondrial	0.025
MRPS23	mitochondrial ribosomal protein S23	0.025
SSBP1	single-stranded DNA binding protein 1	0.025
PFAS	phosphoribosylformylglycinamidine synthase	0.024
MRPL39	mitochondrial ribosomal protein L39	0.024
C17orf80	chromosome 17 open reading frame 80	0.024
MRPL24	mitochondrial ribosomal protein L24	0.023
ZNF235	zinc finger protein 235	0.023
MRPL44	mitochondrial ribosomal protein L44	0.023
MRPL55	mitochondrial ribosomal protein L55	0.022
SCO1	SCO cytochrome oxidase deficient homolog 1 (yeast)	0.021
MARS	methionyl-tRNA synthetase	0.021
CHCHD1	coiled-coil-helix-coiled-coil-helix domain containing 1	0.020
C12orf62	chromosome 12 open reading frame 62	0.020
DAP3	death associated protein 3	0.019
MRPL45	mitochondrial ribosomal protein L45	0.018
HSPD1	heat shock 60kDa protein 1 (chaperonin)	0.018
KRT8	keratin 8	0.017
ME2	malic enzyme 2, NAD(+)-dependent, mitochondrial	0.016
MRPS30	mitochondrial ribosomal protein S30	0.016
FBXO22	F-box protein 22	0.016
MRPL47	mitochondrial ribosomal protein L47	0.016
MRPS5	mitochondrial ribosomal protein S5	0.016
TARS2	threonyl-tRNA synthetase 2, mitochondrial (putative)	0.016
CCT3	chaperonin containing TCP1, subunit 3 (gamma)	0.016
NFS1	NFS1 nitrogen fixation 1 homolog (S. cerevisiae)	0.015
MRPL41	mitochondrial ribosomal protein L41	0.015
EIF2B2	eukaryotic translation initiation factor 2B, subunit 2 beta, 39kDa	0.015
COX1	cytochrome c oxidase subunit I	0.015
SURF1	surfeit 1	0.015
SLC7A5	solute carrier family 7 (cationic amino acid transporter, y+ system), member 5	0.014
MRPL21	mitochondrial ribosomal protein L21	0.014
GEMIN4	gem (nuclear organelle) associated protein 4	0.014
MIPEP	mitochondrial intermediate peptidase	0.014
RPUSD3	RNA pseudouridylate synthase domain containing 3	0.014
MTHFD2	methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase	0.013
DNAJA3	DnaJ (Hsp40) homolog, subfamily A, member 3	0.013
COX16	COX16 cytochrome c oxidase assembly homolog (S. cerevisiae)	0.013
AARS	alanyl-tRNA synthetase	0.013
FARS2	phenylalanyl-tRNA synthetase 2, mitochondrial	0.013	Yeast
YARS	tyrosyl-tRNA synthetase	0.013
GUF1	GUF1 GTPase homolog (S. cerevisiae)	0.013
SUPV3L1	suppressor of var1, 3-like 1 (S. cerevisiae)	0.013
PYCR2	pyrroline-5-carboxylate reductase family, member 2	0.013
SFXN4	sideroflexin 4	0.013
C18orf55	chromosome 18 open reading frame 55	0.012
KIAA0391	KIAA0391	0.012
MRPS17	mitochondrial ribosomal protein S17	0.012
TRMT61B	tRNA methyltransferase 61 homolog B (S. cerevisiae)	0.012
NUTF2	nuclear transport factor 2	0.011
PCCB	propionyl CoA carboxylase, beta polypeptide	0.011
HOXB7	homeobox B7	0.011
MRPL10	mitochondrial ribosomal protein L10	0.011
USP22	ubiquitin specific peptidase 22	0.011
MRPS21	mitochondrial ribosomal protein S21	0.011
TRUB2	TruB pseudouridine (psi) synthase homolog 2 (E. coli)	0.011
TRNT1	tRNA nucleotidyl transferase, CCA-adding, 1	0.011
TTC1	tetratricopeptide repeat domain 1	0.011
IDE	insulin-degrading enzyme	0.010
MARS2	methionyl-tRNA synthetase 2, mitochondrial	0.010
TFB1M	transcription factor B1, mitochondrial	0.010
TSEN2	tRNA splicing endonuclease 2 homolog (S. cerevisiae)	0.010