Mus musculus

25 known processes

Aph1a

anterior pharynx defective 1a homolog (C. elegans)

(Aliases: MGC7221,MGC36389,6530402N02Rik)

Aph1a biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
notch receptor processing GO:0007220 4 0.865
regulation of resting membrane potential GO:0060075 3 0.849
beta amyloid metabolic process GO:0050435 14 0.826
copper ion transport GO:0006825 10 0.739
macromolecule glycosylation GO:0043413 55 0.691
lateral inhibition GO:0046331 1 0.622
choline transport GO:0015871 3 0.615
cell fate commitment GO:0045165 210 0.592
photoreceptor cell morphogenesis GO:0008594 3 0.491
membrane protein ectodomain proteolysis GO:0006509 7 0.454
pharynx development GO:0060465 1 0.435
autophagic vacuole assembly GO:0000045 13 0.418
vacuole organization GO:0007033 38 0.374
cellular amide metabolic process GO:0043603 58 0.368
membrane protein proteolysis GO:0033619 10 0.361
peptide metabolic process GO:0006518 46 0.337
epithelial cell proliferation GO:0050673 174 0.314
transition metal ion transport GO:0000041 38 0.308
negative regulation of protein tyrosine kinase activity GO:0061099 3 0.287
photoreceptor cell development GO:0042461 40 0.266
dicarboxylic acid transport GO:0006835 29 0.259
synaptic vesicle localization GO:0097479 59 0.240
myeloid cell homeostasis GO:0002262 114 0.232
neurotransmitter transport GO:0006836 76 0.216
activation of mapkk activity GO:0000186 15 0.214
modification dependent macromolecule catabolic process GO:0043632 133 0.193
swimming behavior GO:0036269 1 0.192
protein maturation GO:0051604 176 0.190
Mouse
photoreceptor cell differentiation GO:0046530 52 0.188
digestive tract development GO:0048565 190 0.188
cation transmembrane transport GO:0098655 266 0.187
negative regulation of epidermal growth factor activated receptor activity GO:0007175 3 0.184
ubiquitin dependent protein catabolic process GO:0006511 129 0.184
carbohydrate metabolic process GO:0005975 230 0.182
cardiac muscle contraction GO:0060048 32 0.181
glycoprotein biosynthetic process GO:0009101 89 0.180
transmembrane transport GO:0055085 412 0.179
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.175
amino acid transport GO:0006865 61 0.171
beta amyloid formation GO:0034205 9 0.166
regulation of epidermal growth factor activated receptor activity GO:0007176 7 0.161
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.158
t cell proliferation GO:0042098 120 0.158
organic acid transport GO:0015849 101 0.156
forebrain development GO:0030900 302 0.153
t cell activation GO:0042110 289 0.151
negative regulation of ubiquitin protein transferase activity GO:0051444 3 0.149
notch signaling pathway GO:0007219 71 0.149
protein modification by small protein conjugation GO:0032446 187 0.146
multi multicellular organism process GO:0044706 109 0.146
cell cell signaling involved in cell fate commitment GO:0045168 35 0.144
cellular ketone metabolic process GO:0042180 84 0.142
telencephalon development GO:0021537 186 0.139
modification dependent protein catabolic process GO:0019941 133 0.139
regulation of neuron differentiation GO:0045664 281 0.136
cellular amino acid metabolic process GO:0006520 103 0.135
regulation of cell projection organization GO:0031344 206 0.135
striated muscle contraction GO:0006941 45 0.135
carbohydrate derivative biosynthetic process GO:1901137 183 0.134
protein processing GO:0016485 163 0.133
Mouse
acidic amino acid transport GO:0015800 16 0.128
protein glycosylation GO:0006486 55 0.127
glycoprotein metabolic process GO:0009100 116 0.126
establishment of organelle localization GO:0051656 122 0.113
leukocyte proliferation GO:0070661 172 0.109
inorganic ion transmembrane transport GO:0098660 234 0.109
endoplasmic reticulum calcium ion homeostasis GO:0032469 11 0.106
nitrogen compound transport GO:0071705 271 0.103
negative regulation of receptor activity GO:2000272 5 0.103
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.102
cerebral cortex cell migration GO:0021795 44 0.102
establishment of synaptic vesicle localization GO:0097480 57 0.101
cellular macromolecule catabolic process GO:0044265 206 0.100
regulation of neuron projection development GO:0010975 169 0.097
organic hydroxy compound transport GO:0015850 93 0.096
cellular protein catabolic process GO:0044257 155 0.096
cellular amine metabolic process GO:0044106 44 0.093
organic cyclic compound catabolic process GO:1901361 295 0.091
exocytosis GO:0006887 121 0.090
l glutamate transport GO:0015813 16 0.089
embryonic organ morphogenesis GO:0048562 276 0.088
positive regulation of protein kinase activity GO:0045860 144 0.086
protein modification by small protein conjugation or removal GO:0070647 207 0.085
negative regulation of kinase activity GO:0033673 81 0.082
cerebral cortex development GO:0021987 86 0.082
neuron death GO:0070997 154 0.081
regulation of apoptotic signaling pathway GO:2001233 197 0.080
cellular divalent inorganic cation homeostasis GO:0072503 127 0.079
negative regulation of extrinsic apoptotic signaling pathway via death domain receptors GO:1902042 11 0.079
amine metabolic process GO:0009308 45 0.078
regulation of receptor recycling GO:0001919 8 0.078
heart contraction GO:0060047 93 0.075
homeostasis of number of cells GO:0048872 210 0.074
leukocyte differentiation GO:0002521 342 0.074
regulation of cellular amino acid metabolic process GO:0006521 5 0.074
carboxylic acid transport GO:0046942 100 0.072
limb development GO:0060173 166 0.072
muscle contraction GO:0006936 101 0.072
inorganic cation transmembrane transport GO:0098662 207 0.071
negative regulation of protein ubiquitination involved in ubiquitin dependent protein catabolic process GO:2000059 6 0.071
establishment of vesicle localization GO:0051650 81 0.070
forebrain cell migration GO:0021885 58 0.069
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.069
meiotic nuclear division GO:0007126 115 0.068
proteasomal protein catabolic process GO:0010498 98 0.067
negative regulation of cellular protein metabolic process GO:0032269 247 0.067
regulation of mapk cascade GO:0043408 248 0.067
cation homeostasis GO:0055080 212 0.064
skeletal system development GO:0001501 356 0.064
hair cycle phase GO:0044851 16 0.064
regulation of cellular amine metabolic process GO:0033238 20 0.063
regulation of protein kinase activity GO:0045859 232 0.063
regulation of kinase activity GO:0043549 249 0.063
regulation of protein serine threonine kinase activity GO:0071900 157 0.062
regulation of neurotransmitter levels GO:0001505 87 0.062
negative regulation of cellular protein catabolic process GO:1903363 22 0.060
regulation of membrane potential GO:0042391 192 0.060
synaptic vesicle transport GO:0048489 57 0.059
cellular ion homeostasis GO:0006873 165 0.058
negative regulation of cellular amine metabolic process GO:0033239 1 0.058
regulation of ion transport GO:0043269 215 0.058
embryonic heart tube development GO:0035050 65 0.057
cellular homeostasis GO:0019725 240 0.057
divalent metal ion transport GO:0070838 172 0.056
regulation of cellular catabolic process GO:0031329 242 0.055
multi organism reproductive behavior GO:0044705 29 0.055
cellular response to extracellular stimulus GO:0031668 81 0.055
positive regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032436 23 0.055
organelle fission GO:0048285 170 0.055
cellular chemical homeostasis GO:0055082 215 0.054
biological phase GO:0044848 20 0.054
peptidyl amino acid modification GO:0018193 336 0.054
calcium ion transport GO:0006816 159 0.054
negative regulation of molecular function GO:0044092 258 0.054
regulation of cellular ketone metabolic process GO:0010565 66 0.054
anagen GO:0042640 13 0.054
nuclear division GO:0000280 158 0.053
circulatory system process GO:0003013 197 0.053
peptidyl tyrosine modification GO:0018212 145 0.052
coagulation GO:0050817 78 0.052
macromolecule catabolic process GO:0009057 281 0.052
neural tube patterning GO:0021532 43 0.052
glycosylation GO:0070085 62 0.052
l amino acid transport GO:0015807 32 0.052
heterocycle catabolic process GO:0046700 280 0.051
positive regulation of apoptotic signaling pathway GO:2001235 95 0.051
response to organic cyclic compound GO:0014070 198 0.050
metal ion homeostasis GO:0055065 189 0.049
positive regulation of proteolysis involved in cellular protein catabolic process GO:1903052 31 0.049
positive regulation of cell death GO:0010942 224 0.049
learning or memory GO:0007611 148 0.048
ion transmembrane transport GO:0034220 361 0.048
heart process GO:0003015 94 0.047
negative regulation of cell development GO:0010721 169 0.047
embryonic appendage morphogenesis GO:0035113 126 0.047
regulation of cell migration GO:0030334 219 0.045
growth involved in heart morphogenesis GO:0003241 4 0.045
cellular response to lipid GO:0071396 145 0.045
divalent inorganic cation homeostasis GO:0072507 138 0.045
cation transport GO:0006812 399 0.044
protein catabolic process GO:0030163 221 0.044
immune response regulating signaling pathway GO:0002764 125 0.044
t cell activation involved in immune response GO:0002286 43 0.044
negative regulation of neuron projection development GO:0010977 50 0.043
multicellular organismal reproductive behavior GO:0033057 23 0.043
purine containing compound metabolic process GO:0072521 311 0.043
negative regulation of apoptotic signaling pathway GO:2001234 104 0.043
receptor recycling GO:0001881 11 0.042
regulation of cellular protein catabolic process GO:1903362 61 0.042
response to organonitrogen compound GO:0010243 246 0.042
somitogenesis GO:0001756 69 0.042
neuron apoptotic process GO:0051402 142 0.042
cell migration involved in endocardial cushion formation GO:0003273 3 0.042
neural tube development GO:0021915 160 0.041
memory GO:0007613 58 0.041
epithelial tube morphogenesis GO:0060562 303 0.040
positive regulation of mapk cascade GO:0043410 170 0.040
organelle assembly GO:0070925 177 0.040
meiotic cell cycle GO:0051321 122 0.039
calcium ion homeostasis GO:0055074 127 0.039
immune effector process GO:0002252 321 0.039
t cell receptor signaling pathway GO:0050852 46 0.039
regulation of phospholipase a2 activity GO:0032429 3 0.039
blood circulation GO:0008015 195 0.038
regulation of mitotic cell cycle GO:0007346 126 0.038
regulation of protein processing GO:0070613 96 0.037
kidney development GO:0001822 213 0.037
myeloid cell differentiation GO:0030099 233 0.037
potassium ion homeostasis GO:0055075 4 0.037
embryonic limb morphogenesis GO:0030326 126 0.036
cellular metal ion homeostasis GO:0006875 151 0.036
negative regulation of phosphorylation GO:0042326 166 0.036
peptidyl tyrosine phosphorylation GO:0018108 143 0.036
cellular response to external stimulus GO:0071496 88 0.036
regulation of secretion GO:0051046 274 0.035
synaptic transmission GO:0007268 329 0.035
response to extracellular stimulus GO:0009991 127 0.035
negative regulation of protein modification by small protein conjugation or removal GO:1903321 20 0.035
respiratory system development GO:0060541 190 0.035
digestive system development GO:0055123 200 0.035
cell activation involved in immune response GO:0002263 126 0.035
respiratory tube development GO:0030323 167 0.035
amyloid precursor protein catabolic process GO:0042987 10 0.035
cellular response to hormone stimulus GO:0032870 150 0.035
gland development GO:0048732 330 0.034
regulation of epithelial cell proliferation GO:0050678 141 0.034
immune response regulating cell surface receptor signaling pathway GO:0002768 80 0.034
sensory perception GO:0007600 245 0.034
nucleotide catabolic process GO:0009166 217 0.034
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 56 0.034
negative regulation of protein processing GO:0010955 79 0.034
somite development GO:0061053 81 0.034
cell type specific apoptotic process GO:0097285 268 0.034
pallium development GO:0021543 120 0.033
cellular lipid metabolic process GO:0044255 323 0.032
positive regulation of kinase activity GO:0033674 155 0.032
negative regulation of protein maturation GO:1903318 79 0.032
vesicle targeting GO:0006903 6 0.032
secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development GO:0060528 4 0.032
hematopoietic progenitor cell differentiation GO:0002244 143 0.032
multi organism behavior GO:0051705 62 0.032
positive regulation of apoptotic process GO:0043065 217 0.032
regulation of transferase activity GO:0051338 263 0.031
glomerular mesangial cell differentiation GO:0072008 3 0.031
purine nucleoside metabolic process GO:0042278 241 0.031
cellular nitrogen compound catabolic process GO:0044270 280 0.031
nucleoside phosphate metabolic process GO:0006753 338 0.031
protein ubiquitination involved in ubiquitin dependent protein catabolic process GO:0042787 25 0.031
posttranscriptional regulation of gene expression GO:0010608 155 0.031
negative regulation of proteolysis involved in cellular protein catabolic process GO:1903051 22 0.031
purine ribonucleotide catabolic process GO:0009154 208 0.030
carbohydrate derivative catabolic process GO:1901136 231 0.030
cellular calcium ion homeostasis GO:0006874 119 0.030
cardiac right atrium morphogenesis GO:0003213 3 0.030
reproductive behavior GO:0019098 32 0.030
cell adhesion GO:0007155 329 0.030
autophagy GO:0006914 45 0.029
negative regulation of phosphorus metabolic process GO:0010563 184 0.029
negative regulation of calcium ion dependent exocytosis GO:0045955 3 0.029
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.029
locomotory behavior GO:0007626 195 0.029
aromatic compound catabolic process GO:0019439 286 0.029
muscle system process GO:0003012 141 0.029
regulation of extrinsic apoptotic signaling pathway via death domain receptors GO:1902041 22 0.029
negative regulation of protein metabolic process GO:0051248 282 0.029
developmental maturation GO:0021700 193 0.029
developmental growth involved in morphogenesis GO:0060560 138 0.028
positive regulation of programmed cell death GO:0043068 218 0.028
positive regulation of protein modification process GO:0031401 299 0.028
positive regulation of map kinase activity GO:0043406 84 0.028
embryonic heart tube morphogenesis GO:0003143 51 0.028
response to starvation GO:0042594 65 0.028
regionalization GO:0003002 337 0.027
camera type eye development GO:0043010 266 0.027
purine nucleotide metabolic process GO:0006163 302 0.027
nucleoside phosphate catabolic process GO:1901292 222 0.027
mapk cascade GO:0000165 281 0.027
glycosyl compound catabolic process GO:1901658 206 0.027
thymus development GO:0048538 41 0.027
nucleoside triphosphate catabolic process GO:0009143 205 0.026
divalent inorganic cation transport GO:0072511 178 0.026
placenta development GO:0001890 140 0.026
nucleoside triphosphate metabolic process GO:0009141 230 0.026
determination of left right symmetry GO:0007368 80 0.026
cellular response to starvation GO:0009267 57 0.026
single organism cell adhesion GO:0098602 156 0.026
ribose phosphate metabolic process GO:0019693 291 0.025
purine nucleoside triphosphate metabolic process GO:0009144 226 0.025
epidermis development GO:0008544 187 0.025
heart morphogenesis GO:0003007 178 0.025
negative regulation of ligase activity GO:0051352 3 0.025
nucleoside metabolic process GO:0009116 246 0.025
ribonucleoside triphosphate metabolic process GO:0009199 220 0.025
synaptic vesicle exocytosis GO:0016079 26 0.025
leukocyte activation involved in immune response GO:0002366 126 0.024
extrinsic apoptotic signaling pathway via death domain receptors GO:0008625 34 0.024
response to oxidative stress GO:0006979 123 0.024
regulation of extrinsic apoptotic signaling pathway GO:2001236 77 0.024
regulation of protein complex assembly GO:0043254 83 0.024
negative regulation of cellular catabolic process GO:0031330 47 0.024
organelle localization GO:0051640 179 0.024
response to radiation GO:0009314 165 0.024
pigmentation GO:0043473 71 0.024
epithelial cell development GO:0002064 159 0.023
sensory organ morphogenesis GO:0090596 242 0.023
morphogenesis of a branching epithelium GO:0061138 193 0.023
cellular response to monosaccharide stimulus GO:0071326 47 0.023
positive regulation of transferase activity GO:0051347 167 0.023
calcium ion transmembrane transport GO:0070588 85 0.022
limb morphogenesis GO:0035108 149 0.022
regulation of coagulation GO:0050818 31 0.022
purine ribonucleotide metabolic process GO:0009150 290 0.022
regulation of cellular component biogenesis GO:0044087 181 0.022
glomerular mesangial cell development GO:0072144 3 0.022
regulation of cell cycle process GO:0010564 160 0.022
axonogenesis GO:0007409 274 0.022
lung development GO:0030324 164 0.022
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 40 0.022
lipid biosynthetic process GO:0008610 179 0.022
segmentation GO:0035282 93 0.022
negative regulation of proteolysis GO:0045861 74 0.022
regulation of mitotic cell cycle phase transition GO:1901990 73 0.022
negative regulation of nervous system development GO:0051961 156 0.022
ribonucleoside triphosphate catabolic process GO:0009203 199 0.021
nucleobase containing small molecule metabolic process GO:0055086 352 0.021
endomembrane system organization GO:0010256 147 0.021
response to growth factor GO:0070848 198 0.021
endocytosis GO:0006897 168 0.021
skeletal system morphogenesis GO:0048705 203 0.021
negative regulation of mesenchymal cell proliferation involved in lung development GO:2000791 2 0.021
regulation of cell migration involved in sprouting angiogenesis GO:0090049 4 0.021
vesicle localization GO:0051648 86 0.021
ribonucleotide catabolic process GO:0009261 208 0.021
lymphocyte activation involved in immune response GO:0002285 93 0.021
neurotransmitter secretion GO:0007269 62 0.021
purine ribonucleoside metabolic process GO:0046128 241 0.020
spermatogenesis GO:0007283 284 0.020
neuroblast fate determination GO:0007400 1 0.020
lymphocyte differentiation GO:0030098 242 0.020
regulation of secretion by cell GO:1903530 249 0.020
kidney vasculature development GO:0061440 15 0.020
negative regulation of cell cycle GO:0045786 123 0.020
regulation of exocytosis GO:0017157 61 0.020
columnar cuboidal epithelial cell differentiation GO:0002065 82 0.020
compound eye development GO:0048749 1 0.020
regulation of organelle organization GO:0033043 289 0.019
negative regulation of protein phosphorylation GO:0001933 126 0.019
regulation of ligase activity GO:0051340 10 0.019
aortic valve morphogenesis GO:0003180 4 0.019
carbohydrate homeostasis GO:0033500 128 0.019
regulation of anion transport GO:0044070 27 0.019
regulation of hydrolase activity GO:0051336 246 0.019
response to symbiont GO:0009608 2 0.019
regulation of proteolysis GO:0030162 164 0.019
carbon catabolite activation of transcription GO:0045991 4 0.018
cellular response to cytokine stimulus GO:0071345 189 0.018
anion transport GO:0006820 177 0.018
cellular response to dna damage stimulus GO:0006974 207 0.018
purine containing compound catabolic process GO:0072523 213 0.018
negative regulation of protein ubiquitination GO:0031397 19 0.018
organophosphate catabolic process GO:0046434 232 0.018
regulation of ph GO:0006885 26 0.018
regulation of hormone levels GO:0010817 211 0.018
regulation of proteasomal protein catabolic process GO:0061136 46 0.018
cardiac chamber development GO:0003205 108 0.018
regulation of endothelial cell chemotaxis GO:2001026 1 0.018
monosaccharide metabolic process GO:0005996 106 0.018
organic anion transport GO:0015711 137 0.018
immune response activating signal transduction GO:0002757 116 0.017
interleukin 8 production GO:0032637 4 0.017
cellular carbohydrate metabolic process GO:0044262 119 0.017
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.017
response to monosaccharide GO:0034284 67 0.017
defense response to other organism GO:0098542 197 0.017
negative regulation of protein catabolic process GO:0042177 36 0.017
negative regulation of wnt signaling pathway GO:0030178 73 0.017
canonical wnt signaling pathway GO:0060070 130 0.017
negative regulation of hormone metabolic process GO:0032351 4 0.017
stem cell development GO:0048864 219 0.017
sensory perception of mechanical stimulus GO:0050954 107 0.017
blood vessel morphogenesis GO:0048514 285 0.017
negative regulation of protein modification process GO:0031400 163 0.017
negative regulation of neuron death GO:1901215 98 0.016
dorsal ventral neural tube patterning GO:0021904 28 0.016
regulation of blood circulation GO:1903522 93 0.016
purine nucleotide catabolic process GO:0006195 211 0.016
fertilization GO:0009566 127 0.016
positive regulation of mammary gland involution GO:1903521 4 0.016
negative regulation of cell projection organization GO:0031345 56 0.016
actin filament based movement GO:0030048 23 0.016
positive regulation of cell migration GO:0030335 109 0.016
regulation of steroid metabolic process GO:0019218 39 0.016
positive regulation of extrinsic apoptotic signaling pathway GO:2001238 34 0.016
negative regulation of erbb signaling pathway GO:1901185 7 0.016
muscle tissue development GO:0060537 308 0.016
maintenance of location GO:0051235 89 0.016
carbon catabolite regulation of transcription from rna polymerase ii promoter GO:0000429 4 0.016
response to nutrient levels GO:0031667 109 0.016
regulation of protein ubiquitination involved in ubiquitin dependent protein catabolic process GO:2000058 14 0.016
nucleotide metabolic process GO:0009117 332 0.015
purine nucleoside triphosphate catabolic process GO:0009146 203 0.015
regulation of wnt signaling pathway GO:0030111 123 0.015
blastocyst development GO:0001824 80 0.015
hormone metabolic process GO:0042445 86 0.015
positive regulation of cellular amine metabolic process GO:0033240 5 0.015
positive regulation of coagulation GO:0050820 13 0.015
mesangial cell differentiation GO:0072007 4 0.015
regulation of organ morphogenesis GO:2000027 144 0.015
positive regulation of protein phosphorylation GO:0001934 242 0.015
plasma membrane organization GO:0007009 90 0.015
ribonucleotide metabolic process GO:0009259 291 0.015
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.015
skin development GO:0043588 220 0.015
stem cell maintenance GO:0019827 130 0.015
cellular response to nutrient levels GO:0031669 64 0.015
regulation of intrinsic apoptotic signaling pathway GO:2001242 61 0.015
protein targeting GO:0006605 143 0.015
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.015
regulation of ion transmembrane transport GO:0034765 119 0.015
carbon catabolite activation of transcription from rna polymerase ii promoter GO:0000436 4 0.015
adult locomotory behavior GO:0008344 91 0.015
urogenital system development GO:0001655 261 0.015
er nucleus signaling pathway GO:0006984 27 0.015
regulation of lipid metabolic process GO:0019216 118 0.015
negative regulation of dendritic spine morphogenesis GO:0061002 3 0.015
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.015
inner ear receptor cell differentiation GO:0060113 61 0.015
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.015
cellular response to growth factor stimulus GO:0071363 197 0.015
regulation of neuron death GO:1901214 134 0.015
regulation of ubiquitin protein transferase activity GO:0051438 7 0.015
nucleoside catabolic process GO:0009164 206 0.015
regulation of map kinase activity GO:0043405 120 0.015
g protein coupled receptor signaling pathway GO:0007186 243 0.015
translation GO:0006412 93 0.014
intracellular protein transport GO:0006886 204 0.014
ear morphogenesis GO:0042471 118 0.014
glial cell differentiation GO:0010001 131 0.014
cellular response to organonitrogen compound GO:0071417 145 0.014
er associated ubiquitin dependent protein catabolic process GO:0030433 10 0.014
anatomical structure homeostasis GO:0060249 145 0.014
negative regulation of canonical wnt signaling pathway GO:0090090 51 0.014
cellular response to organic cyclic compound GO:0071407 87 0.014
negative regulation of anoikis GO:2000811 2 0.014
amide transport GO:0042886 138 0.014
myeloid dendritic cell differentiation GO:0043011 16 0.014
antigen receptor mediated signaling pathway GO:0050851 64 0.014
membrane organization GO:0061024 245 0.014
protein secretion GO:0009306 111 0.014
positive regulation of secretion GO:0051047 130 0.014
negative regulation of mesenchymal cell proliferation GO:0072201 3 0.014
mesangial cell development GO:0072143 4 0.014
action potential GO:0001508 78 0.014
tissue homeostasis GO:0001894 115 0.014
mitochondrion organization GO:0007005 134 0.014
mechanoreceptor differentiation GO:0042490 67 0.014
morphogenesis of a branching structure GO:0001763 203 0.014
appendage development GO:0048736 166 0.014
potassium ion transmembrane transport GO:0071805 43 0.014
telencephalon cell migration GO:0022029 55 0.014
embryonic skeletal system development GO:0048706 120 0.014
striated muscle tissue development GO:0014706 293 0.014
morphogenesis of embryonic epithelium GO:0016331 159 0.014
cartilage development GO:0051216 140 0.014
positive regulation of cellular catabolic process GO:0031331 148 0.014
actin cytoskeleton organization GO:0030036 220 0.013
response to peptide GO:1901652 136 0.013
negative regulation of hormone biosynthetic process GO:0032353 4 0.013
neurotransmitter uptake GO:0001504 14 0.013
regulation of peptidyl tyrosine phosphorylation GO:0050730 93 0.013
morphogenesis of an epithelial sheet GO:0002011 27 0.013
cellular response to insulin stimulus GO:0032869 78 0.013
positive regulation of organelle organization GO:0010638 128 0.013
transcription from rna polymerase iii promoter GO:0006383 3 0.013
neuroblast differentiation GO:0014016 2 0.013
glial cell fate determination GO:0007403 3 0.013
oocyte axis specification GO:0007309 2 0.013
central nervous system neuron differentiation GO:0021953 162 0.013
oligopeptide transmembrane transport GO:0035672 4 0.013
negative regulation of protein complex assembly GO:0031333 25 0.013
response to lipopolysaccharide GO:0032496 128 0.013
ribonucleoside metabolic process GO:0009119 245 0.013
cell division GO:0051301 120 0.013
organophosphate biosynthetic process GO:0090407 122 0.013
regulation of cardioblast differentiation GO:0051890 3 0.013
regulation of cell cycle phase transition GO:1901987 77 0.013
apoptotic signaling pathway GO:0097190 306 0.013
body fluid secretion GO:0007589 53 0.013
muscle cell development GO:0055001 133 0.013
regulation of interleukin 8 production GO:0032677 3 0.013
response to insulin GO:0032868 100 0.013

Aph1a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
myopathy DOID:423 0 0.664
muscular disease DOID:0080000 0 0.664
heart disease DOID:114 0 0.664
cardiomyopathy DOID:0050700 0 0.664
disease of anatomical entity DOID:7 0 0.664
intrinsic cardiomyopathy DOID:0060036 0 0.664
cardiovascular system disease DOID:1287 0 0.664
musculoskeletal system disease DOID:17 0 0.664
muscle tissue disease DOID:66 0 0.664
integumentary system disease DOID:16 0 0.565
skin disease DOID:37 0 0.547
central nervous system disease DOID:331 0 0.287
nervous system disease DOID:863 0 0.287
dementia DOID:1307 0 0.202
alzheimer s disease DOID:10652 0 0.202
disease of mental health DOID:150 0 0.202
tauopathy DOID:680 0 0.202
neurodegenerative disease DOID:1289 0 0.202
cognitive disorder DOID:1561 0 0.202
dilated cardiomyopathy DOID:12930 0 0.042
disease of metabolism DOID:0014667 0 0.030
inherited metabolic disorder DOID:655 0 0.030
brain disease DOID:936 0 0.018
disease of cellular proliferation DOID:14566 0 0.016
cancer DOID:162 0 0.015
organ system cancer DOID:0050686 0 0.015