IMP
Process View
negative regulation of receptor activity
Any process that stops, prevents or reduces the frequency, rate or extent of receptor activity.
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In addition to gene-name show these genes:
Click on a gene's description to view its network relationships with genes known to be involved in "negative regulation of receptor activity"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| Egfr | epidermal growth factor receptor | 0.906 | ||
| Ptpn11 | protein tyrosine phosphatase, non-receptor type 11 | 0.842 | ||
| Grb2 | growth factor receptor bound protein 2 | 0.812 | Fly | |
| Ush1c | Usher syndrome 1C homolog (human) | 0.766 | ||
| Cbl | Casitas B-lineage lymphoma | 0.735 | Fly | |
| Shc1 | src homology 2 domain-containing transforming protein C1 | 0.721 | ||
| Psen1 | presenilin 1 | 0.367 | ||
| Ncstn | nicastrin | 0.304 | ||
| Gab2 | growth factor receptor bound protein 2-associated protein 2 | 0.231 | ||
| Notch2 | Notch gene homolog 2 (Drosophila) | 0.180 | ||
| Cdh5 | cadherin 5 | 0.176 | ||
| Flt1 | FMS-like tyrosine kinase 1 | 0.165 | ||
| Aph1a | anterior pharynx defective 1a homolog (C. elegans) | 0.103 | ||
| Map4k1 | mitogen-activated protein kinase kinase kinase kinase 1 | 0.094 | ||
| 4732456N10Rik | RIKEN cDNA 4732456N10 gene | 0.086 | ||
| Sh3kbp1 | SH3-domain kinase binding protein 1 | 0.062 | ||
| Sos1 | son of sevenless homolog 1 (Drosophila) | 0.051 | ||
| Frs2 | fibroblast growth factor receptor substrate 2 | 0.051 | ||
| Psen2 | presenilin 2 | 0.049 | ||
| Zic3 | zinc finger protein of the cerebellum 3 | 0.041 | ||
| Pcdh15 | protocadherin 15 | 0.041 | ||
| Itsn1 | intersectin 1 (SH3 domain protein 1A) | 0.037 | ||
| Notch1 | Notch gene homolog 1 (Drosophila) | 0.036 | ||
| Ppargc1b | peroxisome proliferative activated receptor, gamma, coactivator 1 beta | 0.034 | ||
| Lefty1 | left right determination factor 1 | 0.025 | ||
| Gnaq | guanine nucleotide binding protein, alpha q polypeptide | 0.024 | ||
| Cav1 | caveolin 1, caveolae protein | 0.021 | ||
| Ptk2 | PTK2 protein tyrosine kinase 2 | 0.018 | ||
| Ticam1 | toll-like receptor adaptor molecule 1 | 0.016 | ||
| Blnk | B-cell linker | 0.015 | ||
| Myd88 | myeloid differentiation primary response gene 88 | 0.015 | ||
| Inpp5d | inositol polyphosphate-5-phosphatase D | 0.014 | ||
| Lrrk1 | leucine-rich repeat kinase 1 | 0.013 | ||
| Crkl | v-crk sarcoma virus CT10 oncogene homolog (avian)-like | 0.013 | ||
| Fyn | Fyn proto-oncogene | 0.013 | ||
| Dnm2 | dynamin 2 | 0.013 | ||
| Gab1 | growth factor receptor bound protein 2-associated protein 1 | 0.012 | ||
| Ptpra | protein tyrosine phosphatase, receptor type, A | 0.012 | ||
| Erlin2 | ER lipid raft associated 2 | 0.012 | ||
| Hey1 | hairy/enhancer-of-split related with YRPW motif 1 | 0.012 | ||
| Rapgef1 | Rap guanine nucleotide exchange factor (GEF) 1 | 0.011 | ||
| Grxcr1 | glutaredoxin, cysteine rich 1 | 0.011 | ||
| Nodal | nodal | 0.011 | ||
| Trp73 | transformation related protein 73 | 0.010 | ||
| Myo15 | myosin XV | 0.010 |