|
|
regulation of b cell mediated immunity
|
GO:0002712 |
37 |
1.000
|
|
|
|
positive regulation of isotype switching to igg isotypes
|
GO:0048304 |
7 |
0.996
|
|
|
|
regulation of lymphocyte proliferation
|
GO:0050670 |
117 |
0.995
|
|
|
|
positive regulation of adaptive immune response
|
GO:0002821 |
61 |
0.992
|
|
|
|
regulation of inflammatory response to antigenic stimulus
|
GO:0002861 |
21 |
0.990
|
|
|
|
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002822 |
87 |
0.989
|
|
|
|
positive regulation of b cell mediated immunity
|
GO:0002714 |
26 |
0.987
|
|
|
|
histamine production involved in inflammatory response
|
GO:0002349 |
1 |
0.987
|
|
|
|
somatic diversification of immune receptors
|
GO:0002200 |
53 |
0.986
|
|
|
|
adaptive immune response
|
GO:0002250 |
155 |
0.986
|
|
|
|
somatic recombination of immunoglobulin genes involved in immune response
|
GO:0002204 |
36 |
0.985
|
|
|
|
regulation of leukocyte mediated immunity
|
GO:0002703 |
104 |
0.985
|
|
|
|
cytokine biosynthetic process
|
GO:0042089 |
68 |
0.985
|
|
|
|
positive regulation of leukocyte mediated immunity
|
GO:0002705 |
70 |
0.978
|
|
|
|
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002460 |
145 |
0.975
|
|
|
|
regulation of immunoglobulin production
|
GO:0002637 |
42 |
0.974
|
|
|
|
regulation of mast cell degranulation
|
GO:0043304 |
16 |
0.974
|
|
|
|
somatic diversification of immunoglobulins involved in immune response
|
GO:0002208 |
36 |
0.973
|
|
|
|
immunoglobulin mediated immune response
|
GO:0016064 |
69 |
0.972
|
|
|
|
somatic recombination of immunoglobulin gene segments
|
GO:0016447 |
42 |
0.972
|
|
|
|
regulation of cytokine biosynthetic process
|
GO:0042035 |
59 |
0.972
|
|
|
|
lymphocyte mediated immunity
|
GO:0002449 |
139 |
0.971
|
|
|
|
b cell activation involved in immune response
|
GO:0002312 |
50 |
0.971
|
|
|
|
positive regulation of cytokine production
|
GO:0001819 |
174 |
0.970
|
|
|
|
regulation of b cell activation
|
GO:0050864 |
81 |
0.969
|
|
|
|
regulation of interleukin 6 production
|
GO:0032675 |
55 |
0.966
|
|
|
|
positive regulation of cell activation
|
GO:0050867 |
158 |
0.963
|
|
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
189 |
0.959
|
Mouse |
|
|
cytokine metabolic process
|
GO:0042107 |
71 |
0.957
|
|
|
|
regulation of immunoglobulin mediated immune response
|
GO:0002889 |
37 |
0.956
|
|
|
|
leukocyte mediated immunity
|
GO:0002443 |
174 |
0.955
|
|
|
|
positive regulation of inflammatory response to antigenic stimulus
|
GO:0002863 |
11 |
0.947
|
|
|
|
t cell proliferation
|
GO:0042098 |
120 |
0.944
|
|
|
|
regulation of cell activation
|
GO:0050865 |
289 |
0.942
|
|
|
|
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002824 |
61 |
0.941
|
|
|
|
b cell mediated immunity
|
GO:0019724 |
71 |
0.940
|
|
|
|
somatic diversification of immunoglobulins
|
GO:0016445 |
43 |
0.935
|
|
|
|
regulation of inflammatory response
|
GO:0050727 |
147 |
0.934
|
|
|
|
immunoglobulin production
|
GO:0002377 |
73 |
0.930
|
|
|
|
positive regulation of intracellular transport
|
GO:0032388 |
70 |
0.927
|
|
|
|
mast cell activation
|
GO:0045576 |
27 |
0.927
|
|
|
|
positive regulation of leukocyte degranulation
|
GO:0043302 |
10 |
0.924
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
266 |
0.915
|
|
|
|
interleukin 10 secretion
|
GO:0072608 |
4 |
0.913
|
|
|
|
regulation of lymphocyte mediated immunity
|
GO:0002706 |
84 |
0.908
|
|
|
|
positive regulation of interleukin 6 production
|
GO:0032755 |
37 |
0.904
|
|
|
|
regulation of b cell proliferation
|
GO:0030888 |
39 |
0.904
|
|
|
|
leukocyte activation involved in immune response
|
GO:0002366 |
126 |
0.897
|
|
|
|
somatic diversification of immune receptors via germline recombination within a single locus
|
GO:0002562 |
51 |
0.895
|
|
|
|
positive regulation of lymphocyte mediated immunity
|
GO:0002708 |
62 |
0.879
|
|
|
|
regulation of response to wounding
|
GO:1903034 |
189 |
0.878
|
|
|
|
inflammatory response to antigenic stimulus
|
GO:0002437 |
30 |
0.876
|
|
|
|
myeloid leukocyte activation
|
GO:0002274 |
83 |
0.876
|
|
|
|
myeloid leukocyte mediated immunity
|
GO:0002444 |
42 |
0.873
|
|
|
|
immunoglobulin secretion
|
GO:0048305 |
17 |
0.873
|
|
|
|
positive regulation of leukocyte proliferation
|
GO:0070665 |
73 |
0.870
|
|
|
|
positive regulation of lymphocyte proliferation
|
GO:0050671 |
70 |
0.867
|
|
|
|
negative regulation of inflammatory response to antigenic stimulus
|
GO:0002862 |
10 |
0.863
|
|
|
|
positive regulation of t cell proliferation
|
GO:0042102 |
52 |
0.863
|
|
|
|
production of molecular mediator of immune response
|
GO:0002440 |
103 |
0.860
|
|
|
|
cell activation involved in immune response
|
GO:0002263 |
126 |
0.855
|
|
|
|
lymphocyte costimulation
|
GO:0031294 |
15 |
0.854
|
|
|
|
myeloid cell differentiation
|
GO:0030099 |
233 |
0.846
|
|
|
|
regulation of adaptive immune response
|
GO:0002819 |
90 |
0.830
|
|
|
|
lymphocyte activation involved in immune response
|
GO:0002285 |
93 |
0.828
|
|
|
|
b cell proliferation
|
GO:0042100 |
53 |
0.821
|
|
|
|
exocytosis
|
GO:0006887 |
121 |
0.821
|
|
|
|
t cell costimulation
|
GO:0031295 |
14 |
0.817
|
|
|
|
positive regulation of immunoglobulin mediated immune response
|
GO:0002891 |
26 |
0.811
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
44 |
0.811
|
|
|
|
positive regulation of cytokine biosynthetic process
|
GO:0042108 |
40 |
0.801
|
|
|
|
regulation of chronic inflammatory response to antigenic stimulus
|
GO:0002874 |
3 |
0.798
|
|
|
|
positive regulation of exocytosis
|
GO:0045921 |
20 |
0.796
|
|
|
|
immune effector process
|
GO:0002252 |
321 |
0.786
|
|
|
|
isotype switching to ige isotypes
|
GO:0048289 |
7 |
0.785
|
|
|
|
regulation of t cell proliferation
|
GO:0042129 |
92 |
0.782
|
|
|
|
positive regulation of mast cell activation involved in immune response
|
GO:0033008 |
10 |
0.778
|
|
|
|
defense response to other organism
|
GO:0098542 |
197 |
0.777
|
|
|
|
t cell selection
|
GO:0045058 |
34 |
0.773
|
|
|
|
positive regulation of acute inflammatory response
|
GO:0002675 |
16 |
0.772
|
|
|
|
humoral immune response mediated by circulating immunoglobulin
|
GO:0002455 |
14 |
0.770
|
|
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
126 |
0.770
|
|
|
|
regulation of mast cell activation involved in immune response
|
GO:0033006 |
17 |
0.770
|
|
|
|
mast cell degranulation
|
GO:0043303 |
19 |
0.759
|
|
|
|
lymphocyte proliferation
|
GO:0046651 |
164 |
0.758
|
|
|
|
regulation of mast cell activation
|
GO:0033003 |
21 |
0.756
|
|
|
|
positive regulation of b cell proliferation
|
GO:0030890 |
24 |
0.739
|
|
|
|
regulation of antigen receptor mediated signaling pathway
|
GO:0050854 |
29 |
0.736
|
|
|
|
amine metabolic process
|
GO:0009308 |
45 |
0.732
|
|
|
|
cytokine mediated signaling pathway
|
GO:0019221 |
115 |
0.729
|
|
|
|
mast cell activation involved in immune response
|
GO:0002279 |
20 |
0.723
|
|
|
|
positive regulation of inflammatory response
|
GO:0050729 |
47 |
0.718
|
|
|
|
regulation of interleukin 2 production
|
GO:0032663 |
28 |
0.708
|
|
|
|
inflammatory response
|
GO:0006954 |
244 |
0.704
|
Mouse |
|
|
lymph node development
|
GO:0048535 |
18 |
0.700
|
|
|
|
chronic inflammatory response
|
GO:0002544 |
9 |
0.699
|
|
|
|
positive regulation of t cell activation
|
GO:0050870 |
101 |
0.696
|
|
|
|
regulation of isotype switching to igg isotypes
|
GO:0048302 |
10 |
0.696
|
|
|
|
positive regulation of defense response
|
GO:0031349 |
124 |
0.695
|
|
|
|
organelle localization
|
GO:0051640 |
179 |
0.683
|
|
|
|
leukocyte degranulation
|
GO:0043299 |
27 |
0.677
|
|
|
|
negative regulation of adaptive immune response
|
GO:0002820 |
25 |
0.672
|
|
|
|
positive regulation of translational initiation
|
GO:0045948 |
4 |
0.671
|
|
|
|
immunoglobulin production involved in immunoglobulin mediated immune response
|
GO:0002381 |
43 |
0.660
|
|
|
|
leukocyte proliferation
|
GO:0070661 |
172 |
0.655
|
|
|
|
myeloid cell activation involved in immune response
|
GO:0002275 |
34 |
0.653
|
|
|
|
positive regulation of lymphocyte activation
|
GO:0051251 |
140 |
0.651
|
|
|
|
positive regulation of jun kinase activity
|
GO:0043507 |
30 |
0.650
|
|
|
|
peptidyl tyrosine modification
|
GO:0018212 |
145 |
0.643
|
|
|
|
positive regulation of chronic inflammatory response
|
GO:0002678 |
4 |
0.642
|
|
|
|
cytokine production
|
GO:0001816 |
319 |
0.635
|
|
|
|
lysosome localization
|
GO:0032418 |
20 |
0.627
|
|
|
|
regulation of acute inflammatory response
|
GO:0002673 |
27 |
0.621
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
159 |
0.619
|
|
|
|
positive regulation of response to wounding
|
GO:1903036 |
66 |
0.616
|
|
|
|
tyrosine phosphorylation of stat5 protein
|
GO:0042506 |
9 |
0.609
|
|
|
|
regulation of lymphocyte activation
|
GO:0051249 |
240 |
0.598
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
170 |
0.581
|
|
|
|
somatic cell dna recombination
|
GO:0016444 |
51 |
0.579
|
|
|
|
alpha beta t cell activation involved in immune response
|
GO:0002287 |
31 |
0.573
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
5 |
0.567
|
|
|
|
leukocyte differentiation
|
GO:0002521 |
342 |
0.561
|
|
|
|
isotype switching to igg isotypes
|
GO:0048291 |
10 |
0.561
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
103 |
0.558
|
|
|
|
regulation of secretion by cell
|
GO:1903530 |
249 |
0.547
|
|
|
|
positive regulation of immune effector process
|
GO:0002699 |
107 |
0.547
|
|
|
|
peptidyl amino acid modification
|
GO:0018193 |
336 |
0.537
|
|
|
|
immune response activating cell surface receptor signaling pathway
|
GO:0002429 |
72 |
0.536
|
|
|
|
defense response to gram positive bacterium
|
GO:0050830 |
50 |
0.535
|
|
|
|
negative regulation of cell activation
|
GO:0050866 |
111 |
0.532
|
|
|
|
lymphocyte differentiation
|
GO:0030098 |
242 |
0.530
|
|
|
|
cellular response to molecule of bacterial origin
|
GO:0071219 |
83 |
0.528
|
|
|
|
dna recombination
|
GO:0006310 |
92 |
0.521
|
|
|
|
t helper 2 cell differentiation
|
GO:0045064 |
12 |
0.515
|
|
|
|
regulation of leukocyte proliferation
|
GO:0070663 |
121 |
0.506
|
|
|
|
regulation of t cell activation
|
GO:0050863 |
170 |
0.497
|
|
|
|
positive regulation of peptidyl tyrosine phosphorylation
|
GO:0050731 |
61 |
0.493
|
|
|
|
regulation of leukocyte differentiation
|
GO:1902105 |
159 |
0.483
|
|
|
|
positive regulation of interleukin 12 production
|
GO:0032735 |
21 |
0.479
|
|
|
|
myeloid leukocyte differentiation
|
GO:0002573 |
119 |
0.478
|
|
|
|
t cell receptor signaling pathway
|
GO:0050852 |
46 |
0.477
|
|
|
|
b cell activation
|
GO:0042113 |
161 |
0.475
|
|
|
|
negative regulation of interleukin 10 secretion
|
GO:2001180 |
2 |
0.472
|
|
|
|
immune complex clearance
|
GO:0002434 |
2 |
0.456
|
|
|
|
positive regulation of sequence specific dna binding transcription factor activity
|
GO:0051091 |
68 |
0.453
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
84 |
0.451
|
|
|
|
gland development
|
GO:0048732 |
330 |
0.449
|
|
|
|
mast cell mediated immunity
|
GO:0002448 |
20 |
0.446
|
|
|
|
immune response regulating cell surface receptor signaling pathway
|
GO:0002768 |
80 |
0.443
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
5 |
0.436
|
|
|
|
negative regulation of interleukin 5 production
|
GO:0032714 |
4 |
0.435
|
|
|
|
acute inflammatory response
|
GO:0002526 |
41 |
0.429
|
|
|
|
metal ion homeostasis
|
GO:0055065 |
189 |
0.421
|
|
|
|
alpha beta t cell activation
|
GO:0046631 |
91 |
0.418
|
|
|
|
regulation of regulated secretory pathway
|
GO:1903305 |
20 |
0.416
|
|
|
|
epithelial cell proliferation
|
GO:0050673 |
174 |
0.410
|
|
|
|
humoral immune response
|
GO:0006959 |
57 |
0.409
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
181 |
0.408
|
|
|
|
interleukin 6 production
|
GO:0032635 |
58 |
0.403
|
|
|
|
striated muscle tissue development
|
GO:0014706 |
293 |
0.402
|
|
|
|
protein secretion
|
GO:0009306 |
111 |
0.401
|
|
|
|
production of molecular mediator involved in inflammatory response
|
GO:0002532 |
21 |
0.397
|
|
|
|
defense response to bacterium
|
GO:0042742 |
119 |
0.395
|
|
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
106 |
0.387
|
|
|
|
response to molecule of bacterial origin
|
GO:0002237 |
143 |
0.387
|
|
|
|
regulation of leukocyte degranulation
|
GO:0043300 |
20 |
0.384
|
|
|
|
positive regulation of protein modification process
|
GO:0031401 |
299 |
0.383
|
|
|
|
negative regulation of interleukin 2 biosynthetic process
|
GO:0045085 |
3 |
0.383
|
|
|
|
alpha beta t cell differentiation
|
GO:0046632 |
69 |
0.377
|
|
|
|
response to peptide
|
GO:1901652 |
136 |
0.376
|
|
|
|
interleukin 4 production
|
GO:0032633 |
24 |
0.376
|
|
|
|
cation transport
|
GO:0006812 |
399 |
0.373
|
|
|
|
salivary gland development
|
GO:0007431 |
37 |
0.371
|
|
|
|
nitrogen compound transport
|
GO:0071705 |
271 |
0.369
|
|
|
|
regulation of epithelial cell proliferation
|
GO:0050678 |
141 |
0.367
|
|
|
|
regulation of exocytosis
|
GO:0017157 |
61 |
0.367
|
|
|
|
immune response activating signal transduction
|
GO:0002757 |
116 |
0.366
|
|
|
|
regulation of striated muscle cell differentiation
|
GO:0051153 |
81 |
0.363
|
|
|
|
tyrosine phosphorylation of stat protein
|
GO:0007260 |
23 |
0.362
|
|
|
|
histamine transport
|
GO:0051608 |
2 |
0.361
|
|
|
|
t helper cell differentiation
|
GO:0042093 |
28 |
0.360
|
|
|
|
positive regulation of innate immune response
|
GO:0045089 |
80 |
0.355
|
|
|
|
corticotropin releasing hormone secretion
|
GO:0043396 |
2 |
0.350
|
|
|
|
positive regulation of granulocyte macrophage colony stimulating factor biosynthetic process
|
GO:0045425 |
2 |
0.340
|
|
|
|
regulation of tumor necrosis factor production
|
GO:0032680 |
49 |
0.338
|
|
|
|
cd4 positive alpha beta t cell differentiation
|
GO:0043367 |
41 |
0.336
|
|
|
|
b cell differentiation
|
GO:0030183 |
78 |
0.334
|
|
|
|
regulation of monocyte extravasation
|
GO:2000437 |
2 |
0.333
|
|
|
|
positive regulation of interferon gamma production
|
GO:0032729 |
39 |
0.333
|
|
|
|
antigen receptor mediated signaling pathway
|
GO:0050851 |
64 |
0.332
|
|
|
|
regulation of map kinase activity
|
GO:0043405 |
120 |
0.331
|
|
|
|
negative regulation of homeostatic process
|
GO:0032845 |
71 |
0.329
|
|
|
|
regulation of protein localization
|
GO:0032880 |
231 |
0.328
|
|
|
|
positive regulation of myeloid leukocyte mediated immunity
|
GO:0002888 |
14 |
0.321
|
|
|
|
t cell differentiation
|
GO:0030217 |
174 |
0.320
|
|
|
|
regulation of secretion
|
GO:0051046 |
274 |
0.320
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
66 |
0.318
|
|
|
|
interleukin 12 production
|
GO:0032615 |
32 |
0.317
|
|
|
|
regulation of interleukin 10 secretion
|
GO:2001179 |
4 |
0.314
|
|
|
|
negative regulation of defense response
|
GO:0031348 |
77 |
0.313
|
|
|
|
mapk cascade
|
GO:0000165 |
281 |
0.313
|
|
|
|
mast cell proliferation
|
GO:0070662 |
4 |
0.305
|
|
|
|
t helper 1 type immune response
|
GO:0042088 |
25 |
0.305
|
|
|
|
regulation of alpha beta t cell proliferation
|
GO:0046640 |
18 |
0.305
|
|
|
|
positive regulation of t cell costimulation
|
GO:2000525 |
2 |
0.303
|
|
|
|
t cell differentiation involved in immune response
|
GO:0002292 |
30 |
0.303
|
|
|
|
calcium ion transport
|
GO:0006816 |
159 |
0.300
|
|
|
|
positive regulation of glial cell proliferation
|
GO:0060252 |
4 |
0.298
|
|
|
|
regulation of stress activated mapk cascade
|
GO:0032872 |
69 |
0.296
|
|
|
|
acute inflammatory response to antigenic stimulus
|
GO:0002438 |
12 |
0.293
|
|
|
|
alpha beta t cell differentiation involved in immune response
|
GO:0002293 |
30 |
0.292
|
|
|
|
negative regulation of inflammatory response
|
GO:0050728 |
61 |
0.290
|
|
|
|
regulation of innate immune response
|
GO:0045088 |
91 |
0.289
|
|
|
|
regulation of protein secretion
|
GO:0050708 |
82 |
0.289
|
|
|
|
regulation of humoral immune response mediated by circulating immunoglobulin
|
GO:0002923 |
10 |
0.287
|
|
|
|
regulation of interleukin 12 production
|
GO:0032655 |
30 |
0.287
|
|
|
|
positive regulation of granulocyte macrophage colony stimulating factor production
|
GO:0032725 |
3 |
0.286
|
|
|
|
positive regulation of chronic inflammatory response to antigenic stimulus
|
GO:0002876 |
2 |
0.282
|
|
|
|
t cell migration
|
GO:0072678 |
19 |
0.280
|
|
|
|
positive regulation of translational initiation by iron
|
GO:0045994 |
2 |
0.280
|
|
|
|
negative regulation of multi organism process
|
GO:0043901 |
68 |
0.278
|
|
|
|
response to amino acid
|
GO:0043200 |
37 |
0.278
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
197 |
0.277
|
|
|
|
regulation of homeostatic process
|
GO:0032844 |
182 |
0.274
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
246 |
0.273
|
|
|
|
positive regulation of muscle cell differentiation
|
GO:0051149 |
39 |
0.271
|
|
|
|
positive regulation of stress activated mapk cascade
|
GO:0032874 |
48 |
0.270
|
|
|
|
sequestering of metal ion
|
GO:0051238 |
19 |
0.269
|
|
|
|
tissue remodeling
|
GO:0048771 |
102 |
0.265
|
|
|
|
regulation of chronic inflammatory response
|
GO:0002676 |
7 |
0.265
|
|
|
|
positive regulation of secretion by cell
|
GO:1903532 |
114 |
0.259
|
|
|
|
negative regulation of immune effector process
|
GO:0002698 |
55 |
0.257
|
|
|
|
morphogenesis of a branching epithelium
|
GO:0061138 |
193 |
0.257
|
|
|
|
regulation of hypersensitivity
|
GO:0002883 |
10 |
0.255
|
|
|
|
regulation of lymphocyte differentiation
|
GO:0045619 |
107 |
0.254
|
|
|
|
hormone secretion
|
GO:0046879 |
128 |
0.252
|
|
|
|
regulation of corticotropin releasing hormone secretion
|
GO:0043397 |
2 |
0.251
|
|
|
|
regulation of protein transport
|
GO:0051223 |
163 |
0.249
|
|
|
|
regulated secretory pathway
|
GO:0045055 |
32 |
0.243
|
|
|
|
positive regulation of alpha beta t cell activation
|
GO:0046635 |
39 |
0.243
|
|
|
|
regulation of type 2 immune response
|
GO:0002828 |
18 |
0.243
|
|
|
|
regulation of defense response
|
GO:0031347 |
233 |
0.240
|
|
|
|
positive regulation of acute inflammatory response to antigenic stimulus
|
GO:0002866 |
7 |
0.239
|
|
|
|
germinal center formation
|
GO:0002467 |
16 |
0.238
|
|
|
|
positive regulation of cd8 positive alpha beta t cell extravasation
|
GO:2000451 |
2 |
0.237
|
|
|
|
cell cell recognition
|
GO:0009988 |
44 |
0.236
|
|
|
|
positive regulation of protein kinase b signaling
|
GO:0051897 |
32 |
0.235
|
|
|
|
positive regulation of tyrosine phosphorylation of stat5 protein
|
GO:0042523 |
6 |
0.233
|
|
|
|
divalent metal ion transport
|
GO:0070838 |
172 |
0.232
|
|
|
|
regulation of alpha beta t cell differentiation
|
GO:0046637 |
35 |
0.232
|
|
|
|
regulation of ion transport
|
GO:0043269 |
215 |
0.231
|
|
|
|
homeostasis of number of cells
|
GO:0048872 |
210 |
0.231
|
|
|
|
leukocyte migration
|
GO:0050900 |
124 |
0.230
|
|
|
|
endodermal cell fate specification
|
GO:0001714 |
4 |
0.227
|
|
|
|
cerebral cortex development
|
GO:0021987 |
86 |
0.225
|
|
|
|
positive regulation of monocyte extravasation
|
GO:2000439 |
1 |
0.224
|
|
|
|
regulation of jnk cascade
|
GO:0046328 |
62 |
0.220
|
|
|
|
regulation of monocyte chemotaxis
|
GO:0090025 |
3 |
0.220
|
|
|
|
positive regulation of humoral immune response
|
GO:0002922 |
11 |
0.219
|
|
|
|
regulation of dna recombination
|
GO:0000018 |
34 |
0.218
|
|
|
|
tumor necrosis factor mediated signaling pathway
|
GO:0033209 |
13 |
0.215
|
|
|
|
muscle cell development
|
GO:0055001 |
133 |
0.214
|
|
|
|
myotube differentiation
|
GO:0014902 |
105 |
0.212
|
|
|
|
positive regulation of tumor necrosis factor production
|
GO:0032760 |
30 |
0.212
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
20 |
0.212
|
|
|
|
regulation of translational initiation
|
GO:0006446 |
15 |
0.210
|
|
|
|
positive regulation of secretion
|
GO:0051047 |
130 |
0.208
|
|
|
|
cytosolic calcium ion transport
|
GO:0060401 |
48 |
0.207
|
|
|
|
positive regulation of map kinase activity
|
GO:0043406 |
84 |
0.206
|
|
|
|
positive regulation of immunological synapse formation
|
GO:2000522 |
1 |
0.203
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.202
|
|
|
|
detection of mechanical stimulus involved in sensory perception of pain
|
GO:0050966 |
4 |
0.201
|
|
|
|
stress activated protein kinase signaling cascade
|
GO:0031098 |
81 |
0.200
|
|
|
|
small molecule biosynthetic process
|
GO:0044283 |
132 |
0.198
|
|
|
|
negative regulation of lymphocyte activation
|
GO:0051250 |
91 |
0.197
|
|
|
|
cellular response to lipopolysaccharide
|
GO:0071222 |
77 |
0.196
|
|
|
|
regulation of jak stat cascade
|
GO:0046425 |
34 |
0.191
|
|
|
|
stress activated mapk cascade
|
GO:0051403 |
80 |
0.191
|
|
|
|
cellular response to amino acid stimulus
|
GO:0071230 |
29 |
0.184
|
|
|
|
regulation of t cell extravasation
|
GO:2000407 |
3 |
0.182
|
|
|
|
lymphocyte migration
|
GO:0072676 |
26 |
0.181
|
|
|
|
cd4 positive cd25 positive alpha beta regulatory t cell differentiation
|
GO:0002361 |
4 |
0.181
|
|
|
|
interferon gamma production
|
GO:0032609 |
67 |
0.180
|
|
|
|
negative regulation of b cell mediated immunity
|
GO:0002713 |
7 |
0.173
|
|
|
|
syncytium formation by plasma membrane fusion
|
GO:0000768 |
42 |
0.171
|
|
|
|
positive regulation of humoral immune response mediated by circulating immunoglobulin
|
GO:0002925 |
6 |
0.171
|
|
|
|
cytokine secretion
|
GO:0050663 |
72 |
0.169
|
|
|
|
activation of mapk activity
|
GO:0000187 |
59 |
0.168
|
|
|
|
regulation of jun kinase activity
|
GO:0043506 |
40 |
0.168
|
|
|
|
muscle tissue development
|
GO:0060537 |
308 |
0.167
|
|
|
|
regulation of humoral immune response
|
GO:0002920 |
22 |
0.166
|
|
|
|
positive regulation of b cell activation
|
GO:0050871 |
49 |
0.164
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
237 |
0.164
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
248 |
0.163
|
|
|
|
intrinsic apoptotic signaling pathway in response to dna damage
|
GO:0008630 |
57 |
0.163
|
|
|
|
positive regulation of regulatory t cell differentiation
|
GO:0045591 |
4 |
0.163
|
|
|
|
jnk cascade
|
GO:0007254 |
72 |
0.162
|
|
|
|
eosinophil activation
|
GO:0043307 |
1 |
0.162
|
|
|
|
thymic t cell selection
|
GO:0045061 |
22 |
0.161
|
|
|
|
bone resorption
|
GO:0045453 |
38 |
0.161
|
|
|
|
regulation of t helper cell differentiation
|
GO:0045622 |
14 |
0.160
|
|
|
|
negative regulation of cytokine production
|
GO:0001818 |
84 |
0.160
|
|
|
|
eosinophil degranulation
|
GO:0043308 |
1 |
0.159
|
|
|
|
positive regulation of isotype switching
|
GO:0045830 |
15 |
0.159
|
|
|
|
translational initiation
|
GO:0006413 |
24 |
0.159
|
|
|
|
regulation of granulocyte macrophage colony stimulating factor production
|
GO:0032645 |
3 |
0.156
|
|
|
|
positive regulation of regulated secretory pathway
|
GO:1903307 |
10 |
0.155
|
|
|
|
regulation of interferon gamma production
|
GO:0032649 |
57 |
0.153
|
|
|
|
positive regulation of podosome assembly
|
GO:0071803 |
3 |
0.152
|
|
|
|
cellular homeostasis
|
GO:0019725 |
240 |
0.152
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
224 |
0.151
|
|
|
|
negative regulation of extrinsic apoptotic signaling pathway
|
GO:2001237 |
45 |
0.150
|
|
|
|
extrinsic apoptotic signaling pathway in absence of ligand
|
GO:0097192 |
55 |
0.150
|
|
|
|
t cell activation
|
GO:0042110 |
289 |
0.149
|
|
|
|
neutrophil apoptotic process
|
GO:0001781 |
3 |
0.148
|
|
|
|
cell chemotaxis
|
GO:0060326 |
81 |
0.148
|
|
|
|
positive regulation of jnk cascade
|
GO:0046330 |
46 |
0.145
|
|
|
|
exocrine system development
|
GO:0035272 |
45 |
0.145
|
|
|
|
response to acid chemical
|
GO:0001101 |
111 |
0.143
|
|
|
|
extracellular matrix organization
|
GO:0030198 |
147 |
0.143
|
|
|
|
necroptotic signaling pathway
|
GO:0097527 |
3 |
0.141
|
|
|
|
interleukin 2 biosynthetic process
|
GO:0042094 |
15 |
0.140
|
|
|
|
regulation of mast cell proliferation
|
GO:0070666 |
4 |
0.139
|
|
|
|
hematopoietic progenitor cell differentiation
|
GO:0002244 |
143 |
0.139
|
|
|
|
response to protozoan
|
GO:0001562 |
28 |
0.138
|
|
|
|
regulation of toll like receptor 2 signaling pathway
|
GO:0034135 |
3 |
0.138
|
|
|
|
type 2 immune response
|
GO:0042092 |
23 |
0.138
|
|
|
|
calcium ion transport into cytosol
|
GO:0060402 |
48 |
0.137
|
|
|
|
negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002823 |
23 |
0.137
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
198 |
0.137
|
|
|
|
isotype switching
|
GO:0045190 |
36 |
0.136
|
|
|
|
release of sequestered calcium ion into cytosol
|
GO:0051209 |
42 |
0.135
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
159 |
0.134
|
|
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
106 |
0.134
|
|
|
|
regulation of osteoclast differentiation
|
GO:0045670 |
36 |
0.130
|
|
|
|
positive regulation of fever generation
|
GO:0031622 |
6 |
0.130
|
|
|
|
myoblast differentiation
|
GO:0045445 |
52 |
0.129
|
|
|
|
tumor necrosis factor production
|
GO:0032640 |
50 |
0.126
|
|
|
|
positive regulation of hematopoietic stem cell migration
|
GO:2000473 |
1 |
0.125
|
|
|
|
regulation of toll like receptor 4 signaling pathway
|
GO:0034143 |
4 |
0.125
|
|
|
|
cardiac muscle cell differentiation
|
GO:0055007 |
69 |
0.124
|
|
|
|
interleukin 10 production
|
GO:0032613 |
23 |
0.123
|
|
|
|
regulation of granulocyte macrophage colony stimulating factor biosynthetic process
|
GO:0045423 |
2 |
0.123
|
|
|
|
regulation of interleukin 2 biosynthetic process
|
GO:0045076 |
13 |
0.122
|
|
|
|
negative regulation of growth of symbiont involved in interaction with host
|
GO:0044146 |
19 |
0.121
|
|
|
|
epidermis development
|
GO:0008544 |
187 |
0.121
|
|
|
|
regulation of vesicle mediated transport
|
GO:0060627 |
139 |
0.120
|
|
|
|
regulation of isotype switching
|
GO:0045191 |
22 |
0.120
|
|
|
|
leukocyte homeostasis
|
GO:0001776 |
79 |
0.119
|
|
|
|
phospholipid metabolic process
|
GO:0006644 |
87 |
0.119
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
155 |
0.118
|
|
|
|
neutrophil differentiation
|
GO:0030223 |
3 |
0.118
|
|
|
|
response to lipopolysaccharide
|
GO:0032496 |
128 |
0.117
|
|
|
|
carboxylic acid transport
|
GO:0046942 |
100 |
0.117
|
|
|
|
signal transduction in absence of ligand
|
GO:0038034 |
55 |
0.115
|
|
|
|
regulation of myeloid leukocyte differentiation
|
GO:0002761 |
58 |
0.115
|
|
|
|
regulation of alpha beta t cell activation
|
GO:0046634 |
53 |
0.114
|
|
|
|
regulation of b cell differentiation
|
GO:0045577 |
23 |
0.114
|
|
|
|
regulation of growth of symbiont in host
|
GO:0044126 |
19 |
0.114
|
|
|
|
negative regulation of myeloid cell differentiation
|
GO:0045638 |
38 |
0.113
|
|
|
|
activation of jun kinase activity
|
GO:0007257 |
15 |
0.112
|
|
|
|
negative regulation of leukocyte differentiation
|
GO:1902106 |
51 |
0.112
|
|
|
|
granulocyte activation
|
GO:0036230 |
10 |
0.112
|
|
|
|
t cell activation involved in immune response
|
GO:0002286 |
43 |
0.112
|
|
|
|
negative regulation of alpha beta t cell activation
|
GO:0046636 |
18 |
0.112
|
|
|
|
protein localization to nucleus
|
GO:0034504 |
121 |
0.111
|
|
|
|
divalent inorganic cation homeostasis
|
GO:0072507 |
138 |
0.110
|
|
|
|
positive regulation of mast cell activation
|
GO:0033005 |
12 |
0.109
|
|
|
|
alpha beta t cell proliferation
|
GO:0046633 |
21 |
0.108
|
|
|
|
defense response to protozoan
|
GO:0042832 |
25 |
0.107
|
|
|
|
regulation of fever generation by regulation of prostaglandin secretion
|
GO:0071810 |
2 |
0.107
|
|
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
112 |
0.107
|
|
|
|
positive regulation of gamma delta t cell differentiation
|
GO:0045588 |
6 |
0.106
|
|
|
|
regulation of interleukin 10 production
|
GO:0032653 |
21 |
0.106
|
|
|
|
regulation of dendritic cell chemotaxis
|
GO:2000508 |
1 |
0.105
|
|
|
|
regulation of muscle tissue development
|
GO:1901861 |
97 |
0.105
|
|
|
|
immune response regulating signaling pathway
|
GO:0002764 |
125 |
0.104
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
159 |
0.104
|
|
|
|
regulation of mhc class ii biosynthetic process
|
GO:0045346 |
7 |
0.104
|
|
|
|
regulation of interleukin 4 biosynthetic process
|
GO:0045402 |
3 |
0.102
|
|
|
|
carboxylic acid biosynthetic process
|
GO:0046394 |
86 |
0.102
|
|
|
|
interleukin 2 production
|
GO:0032623 |
33 |
0.102
|
|
|
|
regulation of isotype switching to ige isotypes
|
GO:0048293 |
7 |
0.102
|
|
|
|
regulation of t cell anergy
|
GO:0002667 |
4 |
0.102
|
|
|
|
cellular response to lipid
|
GO:0071396 |
145 |
0.101
|
|
|
|
tumor necrosis factor superfamily cytokine production
|
GO:0071706 |
51 |
0.101
|
|
|
|
cd4 positive alpha beta t cell differentiation involved in immune response
|
GO:0002294 |
28 |
0.100
|
|
|
|
regulation of t cell costimulation
|
GO:2000523 |
2 |
0.099
|
|
|
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
143 |
0.098
|
|
|
|
positive regulation of immunoglobulin production
|
GO:0002639 |
28 |
0.098
|
|
|
|
regulation of cd4 positive alpha beta t cell activation
|
GO:2000514 |
24 |
0.098
|
|
|
|
positive regulation of myotube differentiation
|
GO:0010831 |
24 |
0.097
|
|
|
|
cellular response to external stimulus
|
GO:0071496 |
88 |
0.097
|
|
|
|
covalent chromatin modification
|
GO:0016569 |
163 |
0.096
|
|
|
|
negative regulation of chronic inflammatory response
|
GO:0002677 |
3 |
0.096
|
|
|
|
fever generation
|
GO:0001660 |
7 |
0.095
|
|
|
|
gliogenesis
|
GO:0042063 |
141 |
0.095
|
|
|
|
chronic inflammatory response to antigenic stimulus
|
GO:0002439 |
3 |
0.095
|
|
|
|
hypersensitivity
|
GO:0002524 |
10 |
0.095
|
|
|
|
regulation of tumor necrosis factor superfamily cytokine production
|
GO:1903555 |
50 |
0.094
|
|
|
|
regulation of eosinophil degranulation
|
GO:0043309 |
1 |
0.093
|
|
|
|
regulation of membrane potential
|
GO:0042391 |
192 |
0.092
|
|
|
|
regulation of myotube differentiation
|
GO:0010830 |
62 |
0.092
|
|
|
|
cytosolic calcium ion homeostasis
|
GO:0051480 |
70 |
0.091
|
|
|
|
negative regulation of response to wounding
|
GO:1903035 |
77 |
0.091
|
|
|
|
eosinophil mediated immunity
|
GO:0002447 |
1 |
0.090
|
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
215 |
0.090
|
|
|
|
salivary gland morphogenesis
|
GO:0007435 |
33 |
0.089
|
|
|
|
t helper 1 cell lineage commitment
|
GO:0002296 |
2 |
0.087
|
|
|
|
positive regulation of cytoplasmic transport
|
GO:1903651 |
40 |
0.087
|
|
|
|
b cell receptor signaling pathway
|
GO:0050853 |
20 |
0.087
|
|
|
|
regulation of tumor necrosis factor biosynthetic process
|
GO:0042534 |
10 |
0.087
|
|
|
|
fatty acid biosynthetic process
|
GO:0006633 |
41 |
0.087
|
|
|
|
negative regulation of mast cell proliferation
|
GO:0070667 |
1 |
0.087
|
|
|
|
positive regulation of myeloid cell differentiation
|
GO:0045639 |
43 |
0.086
|
|
|
|
cd4 positive alpha beta t cell lineage commitment
|
GO:0043373 |
6 |
0.085
|
|
|
|
histamine secretion
|
GO:0001821 |
1 |
0.085
|
|
|
|
regulation of t cell receptor signaling pathway
|
GO:0050856 |
21 |
0.085
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
157 |
0.085
|
|
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
145 |
0.085
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
167 |
0.084
|
|
|
|
negative regulation of molecular function
|
GO:0044092 |
258 |
0.084
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
323 |
0.084
|
|
|
|
positive regulation of activated t cell proliferation
|
GO:0042104 |
8 |
0.084
|
|
|
|
negative regulation of t cell activation
|
GO:0050868 |
65 |
0.083
|
|
|
|
cd4 positive or cd8 positive alpha beta t cell lineage commitment
|
GO:0043369 |
8 |
0.083
|
|
|
|
synaptic transmission
|
GO:0007268 |
329 |
0.083
|
|
|
|
jak stat cascade
|
GO:0007259 |
42 |
0.083
|
|
|
|
positive regulation of transcription factor import into nucleus
|
GO:0042993 |
8 |
0.083
|
|
|
|
organic acid biosynthetic process
|
GO:0016053 |
86 |
0.082
|
|
|
|
positive regulation of mast cell degranulation
|
GO:0043306 |
10 |
0.082
|
|
|
|
inorganic ion transmembrane transport
|
GO:0098660 |
234 |
0.082
|
|
|
|
heat generation
|
GO:0031649 |
13 |
0.082
|
|
|
|
regulation of branching involved in salivary gland morphogenesis
|
GO:0060693 |
11 |
0.082
|
|
|
|
regulation of calcium mediated signaling
|
GO:0050848 |
19 |
0.081
|
|
|
|
negative regulation of secretion
|
GO:0051048 |
61 |
0.081
|
|
|
|
negative regulation of immune system process
|
GO:0002683 |
209 |
0.080
|
|
|
|
regulation of cd4 positive alpha beta t cell differentiation
|
GO:0043370 |
21 |
0.080
|
|
|
|
positive regulation of protein localization to nucleus
|
GO:1900182 |
30 |
0.079
|
|
|
|
extracellular structure organization
|
GO:0043062 |
148 |
0.079
|
|
|
|
lymphocyte homeostasis
|
GO:0002260 |
64 |
0.079
|
|
|
|
positive regulation of t cell differentiation
|
GO:0045582 |
52 |
0.077
|
Human |
|
|
regulation of transferase activity
|
GO:0051338 |
263 |
0.077
|
|
|
|
chromatin modification
|
GO:0016568 |
187 |
0.076
|
|
|
|
monocyte extravasation
|
GO:0035696 |
2 |
0.076
|
|
|
|
regulation of t cell differentiation
|
GO:0045580 |
83 |
0.075
|
|
|
|
azole transport
|
GO:0045117 |
6 |
0.075
|
|
|
|
positive regulation of ion transport
|
GO:0043270 |
65 |
0.075
|
|
|
|
t cell differentiation in thymus
|
GO:0033077 |
77 |
0.074
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
242 |
0.074
|
|
|
|
growth of symbiont involved in interaction with host
|
GO:0044116 |
23 |
0.074
|
|
|
|
cognition
|
GO:0050890 |
149 |
0.074
|
|
|
|
regulation of fever generation
|
GO:0031620 |
6 |
0.073
|
|
|
|
multicellular organismal homeostasis
|
GO:0048871 |
164 |
0.073
|
|
|
|
nuclear import
|
GO:0051170 |
95 |
0.073
|
|
|
|
positive regulation of tumor necrosis factor superfamily cytokine production
|
GO:1903557 |
31 |
0.073
|
|
|
|
organic hydroxy compound metabolic process
|
GO:1901615 |
203 |
0.072
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
77 |
0.072
|
|
|
|
cellular calcium ion homeostasis
|
GO:0006874 |
119 |
0.072
|
|
|
|
wnt signaling pathway
|
GO:0016055 |
188 |
0.072
|
|
|
|
learning or memory
|
GO:0007611 |
148 |
0.072
|
|
|
|
positive regulation of calcium mediated signaling
|
GO:0050850 |
15 |
0.071
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
144 |
0.071
|
|
|
|
regulation of extrinsic apoptotic signaling pathway
|
GO:2001236 |
77 |
0.071
|
|
|
|
sensory perception of sound
|
GO:0007605 |
97 |
0.070
|
|
|
|
chromatin organization
|
GO:0006325 |
206 |
0.070
|
|
|
|
i kappab kinase nf kappab signaling
|
GO:0007249 |
85 |
0.070
|
|
|
|
muscle cell differentiation
|
GO:0042692 |
261 |
0.069
|
|
|
|
skeletal muscle fiber development
|
GO:0048741 |
58 |
0.069
|
|
|
|
positive regulation of protein transport
|
GO:0051222 |
93 |
0.069
|
|
|
|
positive regulation of nf kappab transcription factor activity
|
GO:0051092 |
30 |
0.068
|
|
|
|
regulation of cytokine secretion
|
GO:0050707 |
61 |
0.068
|
|
|
|
negative regulation of toll like receptor 2 signaling pathway
|
GO:0034136 |
3 |
0.068
|
|
|
|
positive t cell selection
|
GO:0043368 |
23 |
0.067
|
|
|
|
regulation of translation
|
GO:0006417 |
71 |
0.067
|
|
|
|
positive regulation of interleukin 2 production
|
GO:0032743 |
19 |
0.067
|
|
|
|
ensheathment of neurons
|
GO:0007272 |
76 |
0.066
|
|
|
|
osteoclast differentiation
|
GO:0030316 |
62 |
0.066
|
|
|
|
histamine secretion by mast cell
|
GO:0002553 |
1 |
0.065
|
|
|
|
amide transport
|
GO:0042886 |
138 |
0.065
|
|
|
|
positive regulation of translation
|
GO:0045727 |
19 |
0.065
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
218 |
0.065
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
306 |
0.064
|
|
|
|
cell fate determination
|
GO:0001709 |
32 |
0.064
|
|
|
|
positive regulation of myoblast differentiation
|
GO:0045663 |
8 |
0.064
|
|
|
|
carbohydrate transport
|
GO:0008643 |
62 |
0.064
|
|
|
|
regulation of epidermis development
|
GO:0045682 |
33 |
0.064
|
|
|
|
regulation of skeletal muscle fiber development
|
GO:0048742 |
36 |
0.064
|
|
|
|
positive regulation of hypersensitivity
|
GO:0002885 |
7 |
0.064
|
|
|
|
histone modification
|
GO:0016570 |
159 |
0.064
|
|
|
|
positive regulation of production of molecular mediator of immune response
|
GO:0002702 |
45 |
0.063
|
|
|
|
positive regulation of synaptic plasticity
|
GO:0031915 |
4 |
0.063
|
|
|
|
positive regulation of homeostatic process
|
GO:0032846 |
64 |
0.063
|
|
|
|
protein kinase b signaling
|
GO:0043491 |
74 |
0.062
|
|
|
|
sensory perception
|
GO:0007600 |
245 |
0.062
|
|
|
|
liver development
|
GO:0001889 |
66 |
0.062
|
|
