IMP
Process View
positive regulation of isotype switching to igg isotypes
Any process that activates or increases the frequency, rate or extent of isotype switching to IgG isotypes.
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Click on a gene's description to view its network relationships with genes known to be involved in "positive regulation of isotype switching to igg isotypes"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| Ifng | interferon gamma | 1.000 | ||
| Tnf | tumor necrosis factor | 1.000 | ||
| Rag1 | recombination activating gene 1 | 0.999 | ||
| Tcra | T-cell receptor alpha chain | 0.996 | ||
| Il4 | interleukin 4 | 0.996 | ||
| Map3k14 | mitogen-activated protein kinase kinase kinase 14 | 0.995 | ||
| Foxp3 | forkhead box P3 | 0.991 | ||
| Nfkb2 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100 | 0.986 | ||
| Il10 | interleukin 10 | 0.986 | ||
| Cd19 | CD19 antigen | 0.983 | ||
| Fyn | Fyn proto-oncogene | 0.975 | ||
| Rag2 | recombination activating gene 2 | 0.971 | ||
| Ikzf1 | IKAROS family zinc finger 1 | 0.964 | ||
| Fas | Fas (TNF receptor superfamily member 6) | 0.963 | ||
| Tnfrsf1a | tumor necrosis factor receptor superfamily, member 1a | 0.959 | ||
| Cd28 | CD28 antigen | 0.942 | ||
| Lta | lymphotoxin A | 0.899 | ||
| Il2rg | interleukin 2 receptor, gamma chain | 0.879 | ||
| Igh | immunoglobulin heavy chain complex | 0.869 | ||
| Prf1 | perforin 1 (pore forming protein) | 0.770 | ||
| Il6 | interleukin 6 | 0.682 | ||
| Pitx1 | paired-like homeodomain transcription factor 1 | 0.614 | ||
| Foxn1 | forkhead box N1 | 0.598 | ||
| Lat | linker for activation of T cells | 0.564 | ||
| Il2 | interleukin 2 | 0.540 | ||
| Tnfsf11 | tumor necrosis factor (ligand) superfamily, member 11 | 0.450 | ||
| Tbx3 | T-box 3 | 0.440 | Mouse | |
| Cd247 | CD247 antigen | 0.297 | ||
| Socs1 | suppressor of cytokine signaling 1 | 0.266 | ||
| Mmp9 | matrix metallopeptidase 9 | 0.218 | ||
| Hoxa1 | homeobox A1 | 0.203 | ||
| Icos | inducible T-cell co-stimulator | 0.195 | Mouse | |
| Inpp5d | inositol polyphosphate-5-phosphatase D | 0.191 | ||
| Nkx2-5 | NK2 transcription factor related, locus 5 (Drosophila) | 0.179 | ||
| Tnfrsf9 | tumor necrosis factor receptor superfamily, member 9 | 0.177 | ||
| Card11 | caspase recruitment domain family, member 11 | 0.163 | ||
| Nos2 | nitric oxide synthase 2, inducible | 0.152 | ||
| Tbx5 | T-box 5 | 0.132 | Mouse | |
| Cd40 | CD40 antigen | 0.125 | ||
| Lyn | Yamaguchi sarcoma viral (v-yes-1) oncogene homolog | 0.112 | ||
| Sh2d1a | SH2 domain protein 1A | 0.098 | ||
| Zap70 | zeta-chain (TCR) associated protein kinase | 0.098 | ||
| Cd40lg | CD40 ligand | 0.094 | ||
| Lyz2 | lysozyme 2 | 0.091 | ||
| Hcn4 | hyperpolarization-activated, cyclic nucleotide-gated K+ 4 | 0.083 | ||
| Fasl | Fas ligand (TNF superfamily, member 6) | 0.083 | ||
| Foxg1 | forkhead box G1 | 0.081 | ||
| Aire | autoimmune regulator (autoimmune polyendocrinopathy candidiasis ectodermal dystrophy) | 0.080 | ||
| Scn5a | sodium channel, voltage-gated, type V, alpha | 0.077 | ||
| Chd7 | chromodomain helicase DNA binding protein 7 | 0.069 | ||
| Btk | Bruton agammaglobulinemia tyrosine kinase | 0.065 | ||
| Tlr4 | toll-like receptor 4 | 0.063 | ||
| Cd4 | CD4 antigen | 0.054 | ||
| Pdcd1 | programmed cell death 1 | 0.054 | ||
| Ptgs2 | prostaglandin-endoperoxide synthase 2 | 0.051 | ||
| Relb | avian reticuloendotheliosis viral (v-rel) oncogene related B | 0.051 | ||
| Nlrp3 | NLR family, pyrin domain containing 3 | 0.044 | ||
| Nfkb1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1, p105 | 0.042 | ||
| Il2rb | interleukin 2 receptor, beta chain | 0.041 | ||
| Tnfsf14 | tumor necrosis factor (ligand) superfamily, member 14 | 0.040 | ||
| Il27ra | interleukin 27 receptor, alpha | 0.040 | ||
| Cd79a | CD79A antigen (immunoglobulin-associated alpha) | 0.038 | ||
| Pik3cd | phosphatidylinositol 3-kinase catalytic delta polypeptide | 0.035 | ||
| Il17a | interleukin 17A | 0.035 | ||
| Il21r | interleukin 21 receptor | 0.035 | ||
| Ltb | lymphotoxin B | 0.034 | ||
| Tbx21 | T-box 21 | 0.032 | ||
| Lck | lymphocyte protein tyrosine kinase | 0.030 | ||
| Gja5 | gap junction protein, alpha 5 | 0.029 | ||
| Itk | IL2-inducible T-cell kinase | 0.029 | ||
| Lif | leukemia inhibitory factor | 0.028 | ||
| Ccl2 | chemokine (C-C motif) ligand 2 | 0.026 | ||
| Slamf1 | signaling lymphocytic activation molecule family member 1 | 0.022 | ||
| Il13 | interleukin 13 | 0.021 | Mouse | |
| B2m | beta-2 microglobulin | 0.021 | ||
| Ccr6 | chemokine (C-C motif) receptor 6 | 0.021 | ||
| Cebpb | CCAAT/enhancer binding protein (C/EBP), beta | 0.021 | ||
| Tnfrsf4 | tumor necrosis factor receptor superfamily, member 4 | 0.021 | ||
| Traf6 | TNF receptor-associated factor 6 | 0.021 | ||
| Zeb1 | zinc finger E-box binding homeobox 1 | 0.019 | ||
| Six1 | sine oculis-related homeobox 1 homolog (Drosophila) | 0.019 | ||
| Sall4 | sal-like 4 (Drosophila) | 0.019 | ||
| Hmx3 | H6 homeobox 3 | 0.019 | ||
| Pax2 | paired box gene 2 | 0.018 | ||
| Tnfrsf1b | tumor necrosis factor receptor superfamily, member 1b | 0.018 | Mouse | |
| Gata3 | GATA binding protein 3 | 0.018 | ||
| Map3k7 | mitogen-activated protein kinase kinase kinase 7 | 0.018 | ||
| Traf2 | TNF receptor-associated factor 2 | 0.018 | ||
| Mefv | Mediterranean fever | 0.017 | ||
| Pou5f1 | POU domain, class 5, transcription factor 1 | 0.016 | ||
| Cxcr5 | chemokine (C-X-C motif) receptor 5 | 0.016 | ||
| Ighmbp2 | immunoglobulin mu binding protein 2 | 0.014 | ||
| Lmx1a | LIM homeobox transcription factor 1 alpha | 0.013 | ||
| Fcer1g | Fc receptor, IgE, high affinity I, gamma polypeptide | 0.012 | ||
| Csf2 | colony stimulating factor 2 (granulocyte-macrophage) | 0.012 | ||
| Smad6 | MAD homolog 6 (Drosophila) | 0.012 | ||
| H2-Ab1 | histocompatibility 2, class II antigen A, beta 1 | 0.012 | ||
| T | brachyury | 0.011 | Mouse | |
| Fgf10 | fibroblast growth factor 10 | 0.011 | ||
| Ccr1 | chemokine (C-C motif) receptor 1 | 0.011 | ||
| Bcl6 | B-cell leukemia/lymphoma 6 | 0.011 | ||
| Apoe | apolipoprotein E | 0.011 | ||
| Dll4 | delta-like 4 (Drosophila) | 0.011 | ||
| Pdcd1lg2 | programmed cell death 1 ligand 2 | 0.010 | ||
| Ccr7 | chemokine (C-C motif) receptor 7 | 0.010 | ||
| Eya1 | eyes absent 1 homolog (Drosophila) | 0.010 |