Process View
The process in which an immature T cell becomes committed to becoming a CD4-positive, alpha-beta T cell.

In addition to gene-name show these genes:
Click on a gene's description to view its network relationships with genes known to be involved in "cd4 positive alpha beta t cell lineage commitment"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| Stat3 | signal transducer and activator of transcription 3 | 0.999 | Mouse | |
| Foxp3 | forkhead box P3 | 0.992 | ||
| Stat5b | signal transducer and activator of transcription 5B | 0.972 | Mouse | |
| Stat2 | signal transducer and activator of transcription 2 | 0.971 | Mouse | |
| Stat5a | signal transducer and activator of transcription 5A | 0.960 | Mouse | |
| Irf9 | interferon regulatory factor 9 | 0.926 | Mouse | |
| Il4ra | interleukin 4 receptor, alpha | 0.810 | ||
| Ifng | interferon gamma | 0.772 | ||
| Myd88 | myeloid differentiation primary response gene 88 | 0.658 | ||
| Stat6 | signal transducer and activator of transcription 6 | 0.642 | ||
| Mmp9 | matrix metallopeptidase 9 | 0.609 | ||
| Stat1 | signal transducer and activator of transcription 1 | 0.595 | Mouse | |
| Il6st | interleukin 6 signal transducer | 0.543 | ||
| Fas | Fas (TNF receptor superfamily member 6) | 0.515 | ||
| Tnfrsf1b | tumor necrosis factor receptor superfamily, member 1b | 0.514 | ||
| Il10 | interleukin 10 | 0.488 | ||
| Tnfrsf1a | tumor necrosis factor receptor superfamily, member 1a | 0.481 | ||
| Nfkb2 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100 | 0.450 | ||
| Cebpb | CCAAT/enhancer binding protein (C/EBP), beta | 0.450 | ||
| Tnf | tumor necrosis factor | 0.422 | ||
| Tapbp | TAP binding protein | 0.377 | ||
| Irgm2 | immunity-related GTPase family M member 2 | 0.357 | ||
| Il1r1 | interleukin 1 receptor, type I | 0.343 | ||
| Socs1 | suppressor of cytokine signaling 1 | 0.301 | ||
| Il27ra | interleukin 27 receptor, alpha | 0.233 | ||
| Tap2 | transporter 2, ATP-binding cassette, sub-family B (MDR/TAP) | 0.227 | ||
| Cd28 | CD28 antigen | 0.200 | ||
| Ccl2 | chemokine (C-C motif) ligand 2 | 0.178 | ||
| Lyz2 | lysozyme 2 | 0.159 | ||
| Rela | v-rel reticuloendotheliosis viral oncogene homolog A (avian) | 0.156 | ||
| Prf1 | perforin 1 (pore forming protein) | 0.149 | ||
| Uba7 | ubiquitin-like modifier activating enzyme 7 | 0.137 | ||
| Irf5 | interferon regulatory factor 5 | 0.135 | Mouse | |
| Cd19 | CD19 antigen | 0.134 | ||
| Trim21 | tripartite motif-containing 21 | 0.122 | ||
| Psmb9 | proteasome (prosome, macropain) subunit, beta type 9 (large multifunctional peptidase 2) | 0.111 | ||
| Tnfrsf9 | tumor necrosis factor receptor superfamily, member 9 | 0.107 | ||
| Pdcd1 | programmed cell death 1 | 0.100 | ||
| Psmb8 | proteasome (prosome, macropain) subunit, beta type 8 (large multifunctional peptidase 7) | 0.100 | ||
| Igtp | interferon gamma induced GTPase | 0.099 | ||
| Trp53 | transformation related protein 53 | 0.097 | ||
| Relb | avian reticuloendotheliosis viral (v-rel) oncogene related B | 0.090 | ||
| Il4 | interleukin 4 | 0.085 | ||
| Socs3 | suppressor of cytokine signaling 3 | 0.085 | ||
| Il2 | interleukin 2 | 0.085 | ||
| Ifnar2 | interferon (alpha and beta) receptor 2 | 0.075 | ||
| Ptpn6 | protein tyrosine phosphatase, non-receptor type 6 | 0.073 | ||
| Il6 | interleukin 6 | 0.070 | ||
| Kit | kit oncogene | 0.068 | ||
| Junb | Jun-B oncogene | 0.066 | ||
| Il21r | interleukin 21 receptor | 0.066 | ||
| Batf | basic leucine zipper transcription factor, ATF-like | 0.065 | ||
| Ncoa3 | nuclear receptor coactivator 3 | 0.064 | ||
| Ptgs2 | prostaglandin-endoperoxide synthase 2 | 0.061 | ||
| Batf3 | basic leucine zipper transcription factor, ATF-like 3 | 0.061 | Mouse | |
| H2-K1 | histocompatibility 2, K1, K region | 0.060 | ||
| Zfp36 | zinc finger protein 36 | 0.056 | ||
| Nr3c1 | nuclear receptor subfamily 3, group C, member 1 | 0.055 | ||
| Znfx1 | zinc finger, NFX1-type containing 1 | 0.052 | ||
| Cd40 | CD40 antigen | 0.050 | ||
| Usp18 | ubiquitin specific peptidase 18 | 0.050 | ||
| Parp10 | poly (ADP-ribose) polymerase family, member 10 | 0.049 | ||
| Nfil3 | nuclear factor, interleukin 3, regulated | 0.045 | ||
| Traf2 | TNF receptor-associated factor 2 | 0.044 | ||
| Irf1 | interferon regulatory factor 1 | 0.042 | Mouse | |
| Bcl2l11 | BCL2-like 11 (apoptosis facilitator) | 0.041 | ||
| Esr2 | estrogen receptor 2 (beta) | 0.040 | ||
| Nckap1l | NCK associated protein 1 like | 0.038 | ||
| Mx2 | myxovirus (influenza virus) resistance 2 | 0.038 | ||
| Icos | inducible T-cell co-stimulator | 0.037 | ||
| Bcl3 | B-cell leukemia/lymphoma 3 | 0.037 | ||
| Jak3 | Janus kinase 3 | 0.036 | ||
| Irf8 | interferon regulatory factor 8 | 0.035 | Mouse | |
| Il12b | interleukin 12b | 0.035 | ||
| Arid1b | AT rich interactive domain 1B (SWI-like) | 0.035 | ||
| H2-D1 | histocompatibility 2, D region locus 1 | 0.034 | ||
| Adar | adenosine deaminase, RNA-specific | 0.032 | ||
| Sfpi1 | SFFV proviral integration 1 | 0.031 | ||
| Mvp | major vault protein | 0.030 | ||
| Isg15 | ISG15 ubiquitin-like modifier | 0.029 | ||
| Gbp7 | guanylate binding protein 7 | 0.029 | ||
| Cebpa | CCAAT/enhancer binding protein (C/EBP), alpha | 0.028 | ||
| Il17ra | interleukin 17 receptor A | 0.028 | ||
| Ikzf1 | IKAROS family zinc finger 1 | 0.028 | ||
| Ifi35 | interferon-induced protein 35 | 0.027 | ||
| Irgm1 | immunity-related GTPase family M member 1 | 0.027 | ||
| Lgals9 | lectin, galactose binding, soluble 9 | 0.027 | ||
| Sfn | stratifin | 0.026 | ||
| Tor3a | torsin family 3, member A | 0.026 | ||
| Zbp1 | Z-DNA binding protein 1 | 0.026 | ||
| Lepr | leptin receptor | 0.025 | ||
| Ciita | class II transactivator | 0.025 | ||
| Card11 | caspase recruitment domain family, member 11 | 0.025 | ||
| Tmem173 | transmembrane protein 173 | 0.023 | ||
| Tlr4 | toll-like receptor 4 | 0.023 | ||
| Lyn | Yamaguchi sarcoma viral (v-yes-1) oncogene homolog | 0.023 | ||
| Inpp5d | inositol polyphosphate-5-phosphatase D | 0.021 | ||
| Eif2ak2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.020 | ||
| Prkd2 | protein kinase D2 | 0.020 | ||
| Nos2 | nitric oxide synthase 2, inducible | 0.020 | ||
| Pik3cd | phosphatidylinositol 3-kinase catalytic delta polypeptide | 0.020 | ||
| Itgal | integrin alpha L | 0.020 | ||
| Il12rb1 | interleukin 12 receptor, beta 1 | 0.019 | ||
| Tnfrsf4 | tumor necrosis factor receptor superfamily, member 4 | 0.019 | ||
| Il2rb | interleukin 2 receptor, beta chain | 0.019 | ||
| Cd4 | CD4 antigen | 0.019 | ||
| Nup62-il4i1 | Nup62-Il4i1 protein | 0.019 | ||
| Igh | immunoglobulin heavy chain complex | 0.018 | ||
| Irf7 | interferon regulatory factor 7 | 0.018 | Mouse | |
| Tnfaip3 | tumor necrosis factor, alpha-induced protein 3 | 0.017 | ||
| Rel | reticuloendotheliosis oncogene | 0.017 | ||
| Lag3 | lymphocyte-activation gene 3 | 0.016 | ||
| H2-DMb2 | histocompatibility 2, class II, locus Mb2 | 0.016 | ||
| 1810019J16Rik | RIKEN cDNA 1810019J16 gene | 0.016 | ||
| Irf4 | interferon regulatory factor 4 | 0.016 | ||
| Ccl4 | chemokine (C-C motif) ligand 4 | 0.016 | ||
| Pml | promyelocytic leukemia | 0.015 | ||
| Traf1 | TNF receptor-associated factor 1 | 0.015 | ||
| Ccr7 | chemokine (C-C motif) receptor 7 | 0.014 | ||
| Tcirg1 | T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 protein A3 | 0.014 | ||
| Mx1 | myxovirus (influenza virus) resistance 1 | 0.013 | ||
| Smad3 | MAD homolog 3 (Drosophila) | 0.013 | ||
| Sp100 | nuclear antigen Sp100 | 0.013 | ||
| Pparg | peroxisome proliferator activated receptor gamma | 0.013 | ||
| Cdkn1a | cyclin-dependent kinase inhibitor 1A (P21) | 0.013 | ||
| Tgfb1 | transforming growth factor, beta 1 | 0.013 | ||
| Lep | leptin | 0.013 | ||
| Rc3h1 | RING CCCH (C3H) domains 1 | 0.013 | ||
| Ifnar1 | interferon (alpha and beta) receptor 1 | 0.012 | ||
| Cxcl10 | chemokine (C-X-C motif) ligand 10 | 0.012 | ||
| Rag1 | recombination activating gene 1 | 0.012 | ||
| Il10ra | interleukin 10 receptor, alpha | 0.011 | ||
| Cd79b | CD79B antigen | 0.011 | ||
| Mefv | Mediterranean fever | 0.011 | ||
| Fut7 | fucosyltransferase 7 | 0.011 | ||
| Jak2 | Janus kinase 2 | 0.011 | ||
| Gbp3 | guanylate binding protein 3 | 0.011 | ||
| Esr1 | estrogen receptor 1 (alpha) | 0.011 | ||
| Parp14 | poly (ADP-ribose) polymerase family, member 14 | 0.011 | ||
| Icam1 | intercellular adhesion molecule 1 | 0.010 | ||
| Ccl1 | chemokine (C-C motif) ligand 1 | 0.010 |