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Homo sapiens

1 genes annotated in human

keratinocyte activation

A change in the morphology or behavior of a keratinocyte resulting from exposure to an activating factor such as a cellular or soluble ligand. Upon activation, keratinocytes become migratory and hyperproliferative, and produce growth factors and cytokines.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "keratinocyte activation"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "keratinocyte activation" (in gray)

Name	Description	Probability	Func Analog Organism
KRT15	keratin 15	1.000
KRT19	keratin 19	0.999
KRT17	keratin 17	0.997
KRT18	keratin 18	0.997
TP63	tumor protein p63	0.953
PKP1	plakophilin 1 (ectodermal dysplasia/skin fragility syndrome)	0.860
PPL	periplakin	0.845
KRT6B	keratin 6B	0.770	Human
KRT14	keratin 14	0.559
KRT6A	keratin 6A	0.540	Human
C19orf50	chromosome 19 open reading frame 50	0.496
PPP2R2B	protein phosphatase 2, regulatory subunit B, beta	0.391
ALOX12	arachidonate 12-lipoxygenase	0.304
KRT6C	keratin 6C	0.256	Human
SPRR1A	small proline-rich protein 1A	0.140
KRT5	keratin 5	0.140	Human
KRT1	keratin 1	0.112	Human
KRT34	keratin 34	0.107
KRT9	keratin 9	0.104
KRT2	keratin 2	0.100
KRT75	keratin 75	0.091	Human
KRT16	keratin 16	0.090
TRIM29	tripartite motif containing 29	0.084
TEKT4	tektin 4	0.083
SPRR1B	small proline-rich protein 1B	0.061
S100A2	S100 calcium binding protein A2	0.053
SPRR3	small proline-rich protein 3	0.050
KRT33B	keratin 33B	0.049
FGFR3	fibroblast growth factor receptor 3	0.046
SERPINB5	serpin peptidase inhibitor, clade B (ovalbumin), member 5	0.044
IVL	involucrin	0.042
KRT7	keratin 7	0.042	Human
KRT81	keratin 81	0.041	Human
DSG3	desmoglein 3	0.040
LY6G6C	lymphocyte antigen 6 complex, locus G6C	0.040
LY6D	lymphocyte antigen 6 complex, locus D	0.039
FGFBP1	fibroblast growth factor binding protein 1	0.037
SLURP1	secreted LY6/PLAUR domain containing 1	0.035
KRT4	keratin 4	0.028	Human
LOR	loricrin	0.028
LYPD3	LY6/PLAUR domain containing 3	0.028
CDH3	cadherin 3, type 1, P-cadherin (placental)	0.028
GPR87	G protein-coupled receptor 87	0.026
RABGEF1	RAB guanine nucleotide exchange factor (GEF) 1	0.025
KIAA1217	KIAA1217	0.025
SERPINB3	serpin peptidase inhibitor, clade B (ovalbumin), member 3	0.024
LY6G6F	lymphocyte antigen 6 complex, locus G6F	0.023
C10orf10	chromosome 10 open reading frame 10	0.022
GABRP	gamma-aminobutyric acid (GABA) A receptor, pi	0.022
COL17A1	collagen, type XVII, alpha 1	0.022
GJB3	gap junction protein, beta 3, 31kDa	0.022
RHPN1	rhophilin, Rho GTPase binding protein 1	0.021
KLK7	kallikrein-related peptidase 7	0.021
PKP2	plakophilin 2	0.021
SPRR4	small proline-rich protein 4	0.020
PI3	peptidase inhibitor 3, skin-derived	0.020
KRT23	keratin 23 (histone deacetylase inducible)	0.020
KRT33A	keratin 33A	0.020
KRT32	keratin 32	0.019
IL1F6	interleukin 1 family, member 6 (epsilon)	0.019
FAM107A	family with sequence similarity 107, member A	0.019
KRT84	keratin 84	0.018	Human
SATB2	SATB homeobox 2	0.018
S100A14	S100 calcium binding protein A14	0.018
ITGB6	integrin, beta 6	0.018
C1orf65	chromosome 1 open reading frame 65	0.017
CABLES1	Cdk5 and Abl enzyme substrate 1	0.017
ALB	albumin	0.017
KRT38	keratin 38	0.016
RHCG	Rh family, C glycoprotein	0.016
KLK10	kallikrein-related peptidase 10	0.016
DSC3	desmocollin 3	0.016
SERPINB7	serpin peptidase inhibitor, clade B (ovalbumin), member 7	0.016
ALDH3A1	aldehyde dehydrogenase 3 family, member A1	0.016
KRT82	keratin 82	0.016	Human
KRT85	keratin 85	0.015	Human
SERPINB4	serpin peptidase inhibitor, clade B (ovalbumin), member 4	0.015
GJB5	gap junction protein, beta 5, 31.1kDa	0.015
KRT77	keratin 77	0.015	Human
ZBED2	zinc finger, BED-type containing 2	0.015
KRT36	keratin 36	0.015
KRTAP5-8	keratin associated protein 5-8	0.015
PIK3AP1	phosphoinositide-3-kinase adaptor protein 1	0.015
KRT31	keratin 31	0.015
POM121L12	POM121 membrane glycoprotein-like 12	0.014
GAB2	GRB2-associated binding protein 2	0.014
BNC1	basonuclin 1	0.014
TROAP	trophinin associated protein (tastin)	0.014
TJP1	tight junction protein 1 (zona occludens 1)	0.014
RAPGEF1	Rap guanine nucleotide exchange factor (GEF) 1	0.014
EXOC8	exocyst complex component 8	0.014
PKP3	plakophilin 3	0.014
HOXB6	homeobox B6	0.014
REPS2	RALBP1 associated Eps domain containing 2	0.014
KLK6	kallikrein-related peptidase 6	0.013
CCDC85B	coiled-coil domain containing 85B	0.013
VTCN1	V-set domain containing T cell activation inhibitor 1	0.013
LAMB3	laminin, beta 3	0.013
LCE3D	late cornified envelope 3D	0.012
VAV3	vav 3 guanine nucleotide exchange factor	0.012
KRT83	keratin 83	0.012	Human
PTPN22	protein tyrosine phosphatase, non-receptor type 22 (lymphoid)	0.012
KRT74	keratin 74	0.012	Human
KLK3	kallikrein-related peptidase 3	0.012
RHOU	ras homolog gene family, member U	0.012
LCE1E	late cornified envelope 1E	0.012
SKIL	SKI-like oncogene	0.011
MT4	metallothionein 4	0.011
CLCA2	chloride channel accessory 2	0.011
SERPINB13	serpin peptidase inhibitor, clade B (ovalbumin), member 13	0.011
TCHH	trichohyalin	0.011
KRT27	keratin 27	0.011
KRT3	keratin 3	0.011	Human
PTPRA	protein tyrosine phosphatase, receptor type, A	0.011
IL1F10	interleukin 1 family, member 10 (theta)	0.011
HNF1A	HNF1 homeobox A	0.011
FXYD4	FXYD domain containing ion transport regulator 4	0.010
FZD10	frizzled homolog 10 (Drosophila)	0.010
IGFL1	IGF-like family member 1	0.010
PRAMEF12	PRAME family member 12	0.010
KRT37	keratin 37	0.010
FAT2	FAT tumor suppressor homolog 2 (Drosophila)	0.010