IMP
Process View
The network for 'keratinocyte activation' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.
Multiple Organisms
keratinocyte activation
A change in the morphology or behavior of a keratinocyte resulting from exposure to an activating factor such as a cellular or soluble ligand. Upon activation, keratinocytes become migratory and hyperproliferative, and produce growth factors and cytokines.
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| KRT15 | keratin 15 | 1.000 | |
| KRT19 | keratin 19 | 0.999 | |
| KRT17 | keratin 17 | 0.997 | |
| KRT18 | keratin 18 | 0.997 | |
| TP63 | tumor protein p63 | 0.953 | |
| PKP1 | plakophilin 1 (ectodermal dysplasia/skin fragility syndrome) | 0.860 | |
| PPL | periplakin | 0.845 | |
| KRT6B | keratin 6B | 0.770 | |
| KRT14 | keratin 14 | 0.559 | |
| KRT6A | keratin 6A | 0.540 | |
| C19orf50 | chromosome 19 open reading frame 50 | 0.496 | |
| PPP2R2B | protein phosphatase 2, regulatory subunit B, beta | 0.391 | |
| ALOX12 | arachidonate 12-lipoxygenase | 0.304 | |
| KRT6C | keratin 6C | 0.256 | |
| SPRR1A | small proline-rich protein 1A | 0.140 | |
| KRT5 | keratin 5 | 0.140 | |
| KRT1 | keratin 1 | 0.112 | |
| KRT34 | keratin 34 | 0.107 | |
| KRT9 | keratin 9 | 0.104 | |
| KRT2 | keratin 2 | 0.100 | |
| KRT75 | keratin 75 | 0.091 | |
| KRT16 | keratin 16 | 0.090 | |
| TRIM29 | tripartite motif containing 29 | 0.084 | |
| TEKT4 | tektin 4 | 0.083 | |
| SPRR1B | small proline-rich protein 1B | 0.061 | |
| S100A2 | S100 calcium binding protein A2 | 0.053 | |
| SPRR3 | small proline-rich protein 3 | 0.050 | |
| KRT33B | keratin 33B | 0.049 | |
| FGFR3 | fibroblast growth factor receptor 3 | 0.046 | |
| SERPINB5 | serpin peptidase inhibitor, clade B (ovalbumin), member 5 | 0.044 | |
| IVL | involucrin | 0.042 | |
| KRT7 | keratin 7 | 0.042 | |
| KRT81 | keratin 81 | 0.041 | |
| DSG3 | desmoglein 3 | 0.040 | |
| LY6G6C | lymphocyte antigen 6 complex, locus G6C | 0.040 | |
| LY6D | lymphocyte antigen 6 complex, locus D | 0.039 | |
| FGFBP1 | fibroblast growth factor binding protein 1 | 0.037 | |
| SLURP1 | secreted LY6/PLAUR domain containing 1 | 0.035 | |
| KRT4 | keratin 4 | 0.028 | |
| LOR | loricrin | 0.028 | |
| LYPD3 | LY6/PLAUR domain containing 3 | 0.028 | |
| CDH3 | cadherin 3, type 1, P-cadherin (placental) | 0.028 | |
| GPR87 | G protein-coupled receptor 87 | 0.026 | |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.025 | |
| KIAA1217 | KIAA1217 | 0.025 | |
| SERPINB3 | serpin peptidase inhibitor, clade B (ovalbumin), member 3 | 0.024 | |
| LY6G6F | lymphocyte antigen 6 complex, locus G6F | 0.023 | |
| C10orf10 | chromosome 10 open reading frame 10 | 0.022 | |
| GABRP | gamma-aminobutyric acid (GABA) A receptor, pi | 0.022 | |
| COL17A1 | collagen, type XVII, alpha 1 | 0.022 | |
| GJB3 | gap junction protein, beta 3, 31kDa | 0.022 | |
| RHPN1 | rhophilin, Rho GTPase binding protein 1 | 0.021 | |
| KLK7 | kallikrein-related peptidase 7 | 0.021 | |
| PKP2 | plakophilin 2 | 0.021 | |
| SPRR4 | small proline-rich protein 4 | 0.020 | |
| PI3 | peptidase inhibitor 3, skin-derived | 0.020 | |
| KRT23 | keratin 23 (histone deacetylase inducible) | 0.020 | |
| KRT33A | keratin 33A | 0.020 | |
| KRT32 | keratin 32 | 0.019 | |
| IL1F6 | interleukin 1 family, member 6 (epsilon) | 0.019 | |
| FAM107A | family with sequence similarity 107, member A | 0.019 | |
| KRT84 | keratin 84 | 0.018 | |
| SATB2 | SATB homeobox 2 | 0.018 | |
| S100A14 | S100 calcium binding protein A14 | 0.018 | |
| ITGB6 | integrin, beta 6 | 0.018 | |
| C1orf65 | chromosome 1 open reading frame 65 | 0.017 | |
| CABLES1 | Cdk5 and Abl enzyme substrate 1 | 0.017 | |
| ALB | albumin | 0.017 | |
| KRT38 | keratin 38 | 0.016 | |
| RHCG | Rh family, C glycoprotein | 0.016 | |
| KLK10 | kallikrein-related peptidase 10 | 0.016 | |
| DSC3 | desmocollin 3 | 0.016 | |
| SERPINB7 | serpin peptidase inhibitor, clade B (ovalbumin), member 7 | 0.016 | |
| ALDH3A1 | aldehyde dehydrogenase 3 family, member A1 | 0.016 | |
| KRT82 | keratin 82 | 0.016 | |
| KRT85 | keratin 85 | 0.015 | |
| SERPINB4 | serpin peptidase inhibitor, clade B (ovalbumin), member 4 | 0.015 | |
| GJB5 | gap junction protein, beta 5, 31.1kDa | 0.015 | |
| KRT77 | keratin 77 | 0.015 | |
| ZBED2 | zinc finger, BED-type containing 2 | 0.015 | |
| KRT36 | keratin 36 | 0.015 | |
| KRTAP5-8 | keratin associated protein 5-8 | 0.015 | |
| PIK3AP1 | phosphoinositide-3-kinase adaptor protein 1 | 0.015 | |
| KRT31 | keratin 31 | 0.015 | |
| POM121L12 | POM121 membrane glycoprotein-like 12 | 0.014 | |
| GAB2 | GRB2-associated binding protein 2 | 0.014 | |
| BNC1 | basonuclin 1 | 0.014 | |
| TROAP | trophinin associated protein (tastin) | 0.014 | |
| TJP1 | tight junction protein 1 (zona occludens 1) | 0.014 | |
| RAPGEF1 | Rap guanine nucleotide exchange factor (GEF) 1 | 0.014 | |
| EXOC8 | exocyst complex component 8 | 0.014 | |
| PKP3 | plakophilin 3 | 0.014 | |
| HOXB6 | homeobox B6 | 0.014 | |
| REPS2 | RALBP1 associated Eps domain containing 2 | 0.014 | |
| KLK6 | kallikrein-related peptidase 6 | 0.013 | |
| CCDC85B | coiled-coil domain containing 85B | 0.013 | |
| VTCN1 | V-set domain containing T cell activation inhibitor 1 | 0.013 | |
| LAMB3 | laminin, beta 3 | 0.013 | |
| LCE3D | late cornified envelope 3D | 0.012 | |
| VAV3 | vav 3 guanine nucleotide exchange factor | 0.012 |
