IMP
Process View
negative regulation of heart contraction
Any process that stops, prevents, or reduces the frequency, rate or extent of heart contraction.
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In addition to gene-name show these genes:
Click on a gene's description to view its network relationships with genes known to be involved in "negative regulation of heart contraction"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.637 | ||
| PTPN1 | protein tyrosine phosphatase, non-receptor type 1 | 0.360 | ||
| PLCG1 | phospholipase C, gamma 1 | 0.178 | ||
| GRB2 | growth factor receptor-bound protein 2 | 0.163 | ||
| HDAC6 | histone deacetylase 6 | 0.077 | ||
| CBL | Cas-Br-M (murine) ecotropic retroviral transforming sequence | 0.059 | ||
| PTPRN | protein tyrosine phosphatase, receptor type, N | 0.049 | ||
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.045 | ||
| GIT1 | G protein-coupled receptor kinase interacting ArfGAP 1 | 0.042 | ||
| EGFR | epidermal growth factor receptor | 0.042 | ||
| CAPN2 | calpain 2, (m/II) large subunit | 0.037 | ||
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.032 | ||
| PSEN2 | presenilin 2 (Alzheimer disease 4) | 0.029 | ||
| GNB2 | guanine nucleotide binding protein (G protein), beta polypeptide 2 | 0.027 | ||
| IFNGR1 | interferon gamma receptor 1 | 0.027 | ||
| PDCD6 | programmed cell death 6 | 0.025 | ||
| SH2B1 | SH2B adaptor protein 1 | 0.025 | ||
| IRS1 | insulin receptor substrate 1 | 0.023 | ||
| RPS6KA6 | ribosomal protein S6 kinase, 90kDa, polypeptide 6 | 0.023 | ||
| CALCOCO2 | calcium binding and coiled-coil domain 2 | 0.021 | ||
| IL6ST | interleukin 6 signal transducer (gp130, oncostatin M receptor) | 0.020 | ||
| JAK1 | Janus kinase 1 | 0.020 | ||
| ZFYVE9 | zinc finger, FYVE domain containing 9 | 0.019 | ||
| INSR | insulin receptor | 0.019 | ||
| GNB5 | guanine nucleotide binding protein (G protein), beta 5 | 0.019 | ||
| PTPN11 | protein tyrosine phosphatase, non-receptor type 11 | 0.018 | ||
| SNX17 | sorting nexin 17 | 0.018 | ||
| CAPN1 | calpain 1, (mu/I) large subunit | 0.018 | ||
| SH3BP2 | SH3-domain binding protein 2 | 0.017 | ||
| CMIP | c-Maf-inducing protein | 0.017 | ||
| GHR | growth hormone receptor | 0.016 | ||
| ERBB2 | v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) | 0.016 | ||
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.016 | ||
| SOCS1 | suppressor of cytokine signaling 1 | 0.016 | ||
| KIT | v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog | 0.015 | ||
| DAZAP2 | DAZ associated protein 2 | 0.015 | ||
| NOS1AP | nitric oxide synthase 1 (neuronal) adaptor protein | 0.014 | ||
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.014 | ||
| ACTR1A | ARP1 actin-related protein 1 homolog A, centractin alpha (yeast) | 0.013 | ||
| SOCS3 | suppressor of cytokine signaling 3 | 0.013 | ||
| LAT | linker for activation of T cells | 0.013 | ||
| PIK3CA | phosphoinositide-3-kinase, catalytic, alpha polypeptide | 0.012 | ||
| PDCD6IP | programmed cell death 6 interacting protein | 0.012 | ||
| TIRAP | toll-interleukin 1 receptor (TIR) domain containing adaptor protein | 0.012 | ||
| CCNG2 | cyclin G2 | 0.011 | ||
| KCNIP3 | Kv channel interacting protein 3, calsenilin | 0.011 | ||
| TACR1 | tachykinin receptor 1 | 0.011 | ||
| SHC1 | SHC (Src homology 2 domain containing) transforming protein 1 | 0.011 | ||
| DAPK1 | death-associated protein kinase 1 | 0.010 | ||
| TBCB | tubulin folding cofactor B | 0.010 | ||
| ARAF | v-raf murine sarcoma 3611 viral oncogene homolog | 0.010 |