IMP

Process View

Homo sapiens

5 genes annotated in human

negative regulation of interleukin 17 production

Any process that stops, prevents, or reduces the frequency, rate, or extent of production of any member of the interleukin-17 family of cytokines.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "negative regulation of interleukin 17 production"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "negative regulation of interleukin 17 production" (in gray)

Name	Description	Probability
IL1R1	interleukin 1 receptor, type I	0.962
TICAM2	toll-like receptor adaptor molecule 2	0.884
TIRAP	toll-interleukin 1 receptor (TIR) domain containing adaptor protein	0.811
MYD88	myeloid differentiation primary response gene (88)	0.802
IL23A	interleukin 23, alpha subunit p19	0.777
LY96	lymphocyte antigen 96	0.279
IL1B	interleukin 1, beta	0.219
IL1R2	interleukin 1 receptor, type II	0.197
IL12A	interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35)	0.193
PLK3	polo-like kinase 3	0.153
IL12B	interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40)	0.080
IL1RAP	interleukin 1 receptor accessory protein	0.049
FHL1	four and a half LIM domains 1	0.045
APP	amyloid beta (A4) precursor protein	0.028
TLR2	toll-like receptor 2	0.022
CCL4	chemokine (C-C motif) ligand 4	0.021
CCL22	chemokine (C-C motif) ligand 22	0.018
HOXA1	homeobox A1	0.018
KIAA1191	KIAA1191	0.015
CCL8	chemokine (C-C motif) ligand 8	0.014
IRAK2	interleukin-1 receptor-associated kinase 2	0.012
SERPINB2	serpin peptidase inhibitor, clade B (ovalbumin), member 2	0.012
SKIL	SKI-like oncogene	0.012
TLR1	toll-like receptor 1	0.012
CCDC149	coiled-coil domain containing 149	0.010
CXCR3	chemokine (C-X-C motif) receptor 3	0.010
IVL	involucrin	0.010