IMP

Process View

Homo sapiens

9 genes annotated in human

lung disease

DOID:850

A lower respiratory tract disease in which the function of the lungs is adversely affected by narrowing or blockage of the airways resulting in poor air flow, a loss of elasticity in the lungs that produces a decrease in the total volume of air that the lungs are able to hold, and clotting, scarring, or inflammation of the blood vessels that affect the ability of the lungs to take up oxygen and to release carbon dioxide.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "lung disease"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "lung disease" (in gray)

Name	Description	Probability
PTPN6	protein tyrosine phosphatase, non-receptor type 6	0.785
DMBT1	deleted in malignant brain tumors 1	0.111
CSF2	colony stimulating factor 2 (granulocyte-macrophage)	0.074
LAIR1	leukocyte-associated immunoglobulin-like receptor 1	0.065
PECAM1	platelet/endothelial cell adhesion molecule	0.053
CD33	CD33 molecule	0.039
SFTPB	surfactant protein B	0.036
LRRC50	leucine rich repeat containing 50	0.034
SFTPA2	surfactant protein A2	0.024
FCGR2B	Fc fragment of IgG, low affinity IIb, receptor (CD32)	0.022
JAK2	Janus kinase 2	0.021
LYN	v-yes-1 Yamaguchi sarcoma viral related oncogene homolog	0.020
SCGB1A1	secretoglobin, family 1A, member 1 (uteroglobin)	0.018
PIGR	polymeric immunoglobulin receptor	0.014
EPOR	erythropoietin receptor	0.014
LCP2	lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)	0.013
IKBKB	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta	0.012
PLEK	pleckstrin	0.012
NCF4	neutrophil cytosolic factor 4, 40kDa	0.012
SFTPC	surfactant protein C	0.006
SLC34A2	solute carrier family 34 (sodium phosphate), member 2	0.004
MUC5B	mucin 5B, oligomeric mucus/gel-forming	0.002
ABCA3	ATP-binding cassette, sub-family A (ABC1), member 3	0.002
CSF2RA	colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage)	0.001
CSF2RB	colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)	0.001
SFTPA1	surfactant protein A1	0.001