IMP

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Homo sapiens

11 genes annotated in human

renal tubular transport disease

DOID:447

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "renal tubular transport disease"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "renal tubular transport disease" (in gray)

Name	Description	Probability	Func Analog Organism
NEDD4L	neural precursor cell expressed, developmentally down-regulated 4-like	1.000
SCNN1A	sodium channel, nonvoltage-gated 1 alpha	0.996	Human
SLC17A1	solute carrier family 17 (sodium phosphate), member 1	0.931
SLC22A6	solute carrier family 22 (organic anion transporter), member 6	0.841
AQP2	aquaporin 2 (collecting duct)	0.750
CLCNKB	chloride channel Kb	0.703
PRODH2	proline dehydrogenase (oxidase) 2	0.648
SLC6A13	solute carrier family 6 (neurotransmitter transporter, GABA), member 13	0.584
SLC28A1	solute carrier family 28 (sodium-coupled nucleoside transporter), member 1	0.344
KCNJ1	potassium inwardly-rectifying channel, subfamily J, member 1	0.300
SLC34A1	solute carrier family 34 (sodium phosphate), member 1	0.289
HNF1B	HNF1 homeobox B	0.226
SLC22A2	solute carrier family 22 (organic cation transporter), member 2	0.205
SLC13A2	solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2	0.154
SLC22A7	solute carrier family 22 (organic anion transporter), member 7	0.150
AQP6	aquaporin 6, kidney specific	0.141
PAX8	paired box 8	0.122
CHRNA4	cholinergic receptor, nicotinic, alpha 4	0.114
HES2	hairy and enhancer of split 2 (Drosophila)	0.110
GH1	growth hormone 1	0.101
GCM1	glial cells missing homolog 1 (Drosophila)	0.096
SLC10A2	solute carrier family 10 (sodium/bile acid cotransporter family), member 2	0.090
TREH	trehalase (brush-border membrane glycoprotein)	0.076
SLC13A3	solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 3	0.067
ATP6V1B1	ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B1	0.063
TBX6	T-box 6	0.062
FOXN1	forkhead box N1	0.061
SLC13A1	solute carrier family 13 (sodium/sulfate symporters), member 1	0.060
ARRDC3	arrestin domain containing 3	0.059
XPNPEP2	X-prolyl aminopeptidase (aminopeptidase P) 2, membrane-bound	0.058
PIGR	polymeric immunoglobulin receptor	0.058
VTCN1	V-set domain containing T cell activation inhibitor 1	0.055
AQP7	aquaporin 7	0.052
CA6	carbonic anhydrase VI	0.052
FUT1	fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group)	0.048
CRYBB3	crystallin, beta B3	0.047
DEFB1	defensin, beta 1	0.042
TTC22	tetratricopeptide repeat domain 22	0.040
UMOD	uromodulin	0.040
GRM5	glutamate receptor, metabotropic 5	0.040
CALCA	calcitonin-related polypeptide alpha	0.039
CYP17A1	cytochrome P450, family 17, subfamily A, polypeptide 1	0.038
STX1A	syntaxin 1A (brain)	0.038
DRD3	dopamine receptor D3	0.037
ADRA1D	adrenergic, alpha-1D-, receptor	0.037
KCNE1	potassium voltage-gated channel, Isk-related family, member 1	0.036
RNF11	ring finger protein 11	0.035
AGXT	alanine-glyoxylate aminotransferase	0.034
PYY	peptide YY	0.034
KL	klotho	0.033
CDH16	cadherin 16, KSP-cadherin	0.032
SLC6A2	solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2	0.031
FGB	fibrinogen beta chain	0.031
NKX2-1	NK2 homeobox 1	0.030
GUCA2B	guanylate cyclase activator 2B (uroguanylin)	0.030
DPYS	dihydropyrimidinase	0.030
NYX	nyctalopin	0.030
PRKCG	protein kinase C, gamma	0.029
CRYBA1	crystallin, beta A1	0.029
CYP4A11	cytochrome P450, family 4, subfamily A, polypeptide 11	0.028
HPD	4-hydroxyphenylpyruvate dioxygenase	0.028
SFTPB	surfactant protein B	0.028
KNG1	kininogen 1	0.027
PAX2	paired box 2	0.027
NAT8B	N-acetyltransferase 8B (GCN5-related, putative, gene/pseudogene)	0.026
USP2	ubiquitin specific peptidase 2	0.026
PIP	prolactin-induced protein	0.026
ARL3	ADP-ribosylation factor-like 3	0.025
SSTR5	somatostatin receptor 5	0.025
FAM3D	family with sequence similarity 3, member D	0.024
FOXI1	forkhead box I1	0.024
ABCA4	ATP-binding cassette, sub-family A (ABC1), member 4	0.024
SLC12A1	solute carrier family 12 (sodium/potassium/chloride transporters), member 1	0.024
NAT8	N-acetyltransferase 8 (GCN5-related, putative)	0.024
CRISP2	cysteine-rich secretory protein 2	0.022
SERPINC1	serpin peptidase inhibitor, clade C (antithrombin), member 1	0.022
GLP1R	glucagon-like peptide 1 receptor	0.022
ELF5	E74-like factor 5 (ets domain transcription factor)	0.021
GP2	glycoprotein 2 (zymogen granule membrane)	0.021
UPK1B	uroplakin 1B	0.021
PLG	plasminogen	0.021
ABCC2	ATP-binding cassette, sub-family C (CFTR/MRP), member 2	0.021
AMBP	alpha-1-microglobulin/bikunin precursor	0.021
ALPI	alkaline phosphatase, intestinal	0.021
GLRA1	glycine receptor, alpha 1	0.021
TH	tyrosine hydroxylase	0.021
SCGB1D2	secretoglobin, family 1D, member 2	0.021
CHRM1	cholinergic receptor, muscarinic 1	0.020
MT3	metallothionein 3	0.020
SEMG2	semenogelin II	0.020
HSD11B2	hydroxysteroid (11-beta) dehydrogenase 2	0.019
FUT3	fucosyltransferase 3 (galactoside 3(4)-L-fucosyltransferase, Lewis blood group)	0.019
SCGB2A1	secretoglobin, family 2A, member 1	0.019
SLC6A12	solute carrier family 6 (neurotransmitter transporter, betaine/GABA), member 12	0.019
SLC5A11	solute carrier family 5 (sodium/glucose cotransporter), member 11	0.018	Human
ARSE	arylsulfatase E (chondrodysplasia punctata 1)	0.018
WNK1	WNK lysine deficient protein kinase 1	0.018
HOXD3	homeobox D3	0.018
MMP20	matrix metallopeptidase 20	0.018
SMR3A	submaxillary gland androgen regulated protein 3A	0.017
KRT37	keratin 37	0.017
NEU2	sialidase 2 (cytosolic sialidase)	0.017
ESRRB	estrogen-related receptor beta	0.017
ALDOB	aldolase B, fructose-bisphosphate	0.017
LRP2	low density lipoprotein receptor-related protein 2	0.017
BHMT	betaine--homocysteine S-methyltransferase	0.017
GHSR	growth hormone secretagogue receptor	0.017
GCGR	glucagon receptor	0.016
IFNA8	interferon, alpha 8	0.016
BFSP1	beaded filament structural protein 1, filensin	0.016
ATP2A1	ATPase, Ca++ transporting, cardiac muscle, fast twitch 1	0.016
CRP	C-reactive protein, pentraxin-related	0.016
KRT33A	keratin 33A	0.015
MYH8	myosin, heavy chain 8, skeletal muscle, perinatal	0.015
SPINK2	serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor)	0.015
FCGBP	Fc fragment of IgG binding protein	0.015
C2orf83	chromosome 2 open reading frame 83	0.015
CNGB1	cyclic nucleotide gated channel beta 1	0.015
PNLIPRP1	pancreatic lipase-related protein 1	0.015
ENTPD2	ectonucleoside triphosphate diphosphohydrolase 2	0.015
ADAM2	ADAM metallopeptidase domain 2	0.015
NR5A1	nuclear receptor subfamily 5, group A, member 1	0.015
GJB5	gap junction protein, beta 5, 31.1kDa	0.015
OPRK1	opioid receptor, kappa 1	0.015
RHO	rhodopsin	0.015
RORC	RAR-related orphan receptor C	0.014
PMFBP1	polyamine modulated factor 1 binding protein 1	0.014
EDN2	endothelin 2	0.014
FMO1	flavin containing monooxygenase 1	0.014
ADH6	alcohol dehydrogenase 6 (class V)	0.014
EGR4	early growth response 4	0.014
C21orf62	chromosome 21 open reading frame 62	0.014
SLC5A1	solute carrier family 5 (sodium/glucose cotransporter), member 1	0.014	Human
HIST1H1T	histone cluster 1, H1t	0.014
PPY	pancreatic polypeptide	0.014
ARTN	artemin	0.014
KCNJ5	potassium inwardly-rectifying channel, subfamily J, member 5	0.014	Human
KRT35	keratin 35	0.014
IL3	interleukin 3 (colony-stimulating factor, multiple)	0.013
IGLL1	immunoglobulin lambda-like polypeptide 1	0.013
ATP6V0A4	ATPase, H+ transporting, lysosomal V0 subunit a4	0.013
REN	renin	0.013
MUC7	mucin 7, secreted	0.013
GYS2	glycogen synthase 2 (liver)	0.013
CASR	calcium-sensing receptor	0.013
GPR87	G protein-coupled receptor 87	0.013
MYH6	myosin, heavy chain 6, cardiac muscle, alpha	0.013
MUC3A	mucin 3A, cell surface associated	0.013
ARR3	arrestin 3, retinal (X-arrestin)	0.013
TGM5	transglutaminase 5	0.012
GALR3	galanin receptor 3	0.012
SLC1A7	solute carrier family 1 (glutamate transporter), member 7	0.012
DLX4	distal-less homeobox 4	0.012
SLC15A1	solute carrier family 15 (oligopeptide transporter), member 1	0.012
EDAR	ectodysplasin A receptor	0.012
UNC93A	unc-93 homolog A (C. elegans)	0.012
TNP2	transition protein 2 (during histone to protamine replacement)	0.012
SCGB2A2	secretoglobin, family 2A, member 2	0.012
MAG	myelin associated glycoprotein	0.012
LDHC	lactate dehydrogenase C	0.012
ELF3	E74-like factor 3 (ets domain transcription factor, epithelial-specific )	0.012
CYP1A1	cytochrome P450, family 1, subfamily A, polypeptide 1	0.012
OPN1SW	opsin 1 (cone pigments), short-wave-sensitive	0.012
LELP1	late cornified envelope-like proline-rich 1	0.012
ABO	ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase)	0.012
CRYBB1	crystallin, beta B1	0.012
LPA	lipoprotein, Lp(a)	0.012
SEMG1	semenogelin I	0.011
WFDC2	WAP four-disulfide core domain 2	0.011
PTGER3	prostaglandin E receptor 3 (subtype EP3)	0.011
FOLH1	folate hydrolase (prostate-specific membrane antigen) 1	0.011
EVPL	envoplakin	0.011
LHB	luteinizing hormone beta polypeptide	0.011
SERPINB13	serpin peptidase inhibitor, clade B (ovalbumin), member 13	0.011
PBOV1	prostate and breast cancer overexpressed 1	0.011
CRYAA	crystallin, alpha A	0.011
MYH15	myosin, heavy chain 15	0.011
HSD17B3	hydroxysteroid (17-beta) dehydrogenase 3	0.011
GNAT2	guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2	0.011
APOH	apolipoprotein H (beta-2-glycoprotein I)	0.011
HPN	hepsin	0.011
HECW1	HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1	0.011
FUT2	fucosyltransferase 2 (secretor status included)	0.011
TACR1	tachykinin receptor 1	0.011
SLC22A1	solute carrier family 22 (organic cation transporter), member 1	0.011
HOXD10	homeobox D10	0.010
GNRHR	gonadotropin-releasing hormone receptor	0.010
KLKB1	kallikrein B, plasma (Fletcher factor) 1	0.010
MYH7	myosin, heavy chain 7, cardiac muscle, beta	0.010
CLPS	colipase, pancreatic	0.010
CYP4B1	cytochrome P450, family 4, subfamily B, polypeptide 1	0.010
SPRR3	small proline-rich protein 3	0.010
KCNK5	potassium channel, subfamily K, member 5	0.010
GP5	glycoprotein V (platelet)	0.010
GLDC	glycine dehydrogenase (decarboxylating)	0.010
LRRC6	leucine rich repeat containing 6	0.010
IL9R	interleukin 9 receptor	0.010
SLC6A18	solute carrier family 6, member 18	0.010
GBA3	glucosidase, beta, acid 3 (cytosolic)	0.010
MSMB	microseminoprotein, beta-	0.010
INHA	inhibin, alpha	0.010
KCNJ16	potassium inwardly-rectifying channel, subfamily J, member 16	0.010	Human
SLC22A13	solute carrier family 22 (organic anion transporter), member 13	0.010
SLC12A3	solute carrier family 12 (sodium/chloride transporters), member 3	0.005
BSND	Bartter syndrome, infantile, with sensorineural deafness (Barttin)	0.004
SLC5A2	solute carrier family 5 (sodium/glucose cotransporter), member 2	0.004
SCNN1G	sodium channel, nonvoltage-gated 1, gamma	0.003
SCNN1B	sodium channel, nonvoltage-gated 1, beta	0.003
CLCNKA	chloride channel Ka	0.001