IMP

Process View

Homo sapiens

12 genes annotated in human

systemic lupus erythematosus

DOID:9074

A lupus erythematosus that is an inflammation of connective tissue marked by skin rashes, joint pain and swelling, inflammation of the kidneys and inflammation of the tissue surrounding the heart.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "systemic lupus erythematosus"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "systemic lupus erythematosus" (in gray)

Name	Description	Probability
CD80	CD80 molecule	0.250
ZAP70	zeta-chain (TCR) associated protein kinase 70kDa	0.182
LAT	linker for activation of T cells	0.165
CD86	CD86 molecule	0.109
LCK	lymphocyte-specific protein tyrosine kinase	0.060
VAV1	vav 1 guanine nucleotide exchange factor	0.034
CD247	CD247 molecule	0.028
CD3E	CD3e molecule, epsilon (CD3-TCR complex)	0.025
INPP5D	inositol polyphosphate-5-phosphatase, 145kDa	0.023
SYK	spleen tyrosine kinase	0.020
PTPN6	protein tyrosine phosphatase, non-receptor type 6	0.019
CD2	CD2 molecule	0.019
EPOR	erythropoietin receptor	0.017
PTPRC	protein tyrosine phosphatase, receptor type, C	0.017
SHC1	SHC (Src homology 2 domain containing) transforming protein 1	0.010
IRF5	interferon regulatory factor 5	0.003
TLR5	toll-like receptor 5	0.003
CTLA4	cytotoxic T-lymphocyte-associated protein 4	0.002
DNASE1L3	deoxyribonuclease I-like 3	0.002
BANK1	B-cell scaffold protein with ankyrin repeats 1	0.002
CR2	complement component (3d/Epstein Barr virus) receptor 2	0.002
DNASE1	deoxyribonuclease I	0.002
ITGAM	integrin, alpha M (complement component 3 receptor 3 subunit)	0.002
FCGR2B	Fc fragment of IgG, low affinity IIb, receptor (CD32)	0.002
PTPN22	protein tyrosine phosphatase, non-receptor type 22 (lymphoid)	0.002
TREX1	three prime repair exonuclease 1	0.001
PDCD1	programmed cell death 1	0.000