IMP

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Homo sapiens

1 genes annotated in human

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9 cis retinoic acid metabolic process

GO:0042905

The chemical reactions and pathways involving 9-cis-retinoic acid, a metabolically active vitamin A derivative.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "9 cis retinoic acid metabolic process"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "9 cis retinoic acid metabolic process" (in gray)

Name	Description	Probability	Func Analog Organism
ALDH2	aldehyde dehydrogenase 2 family (mitochondrial)	1.000
NUPR1	nuclear protein, transcriptional regulator, 1	0.272
SLC22A1	solute carrier family 22 (organic cation transporter), member 1	0.128
HABP2	hyaluronan binding protein 2	0.117
LIPC	lipase, hepatic	0.089
UGT1A3	UDP glucuronosyltransferase 1 family, polypeptide A3	0.086
CYP4F11	cytochrome P450, family 4, subfamily F, polypeptide 11	0.081
CYP4F12	cytochrome P450, family 4, subfamily F, polypeptide 12	0.075
HAAO	3-hydroxyanthranilate 3,4-dioxygenase	0.071
SPP2	secreted phosphoprotein 2, 24kDa	0.069
CYP4F2	cytochrome P450, family 4, subfamily F, polypeptide 2	0.059
HPX	hemopexin	0.055
AADAC	arylacetamide deacetylase (esterase)	0.051
SAA4	serum amyloid A4, constitutive	0.050
SULT1B1	sulfotransferase family, cytosolic, 1B, member 1	0.050
AKR1C4	aldo-keto reductase family 1, member C4 (chlordecone reductase; 3-alpha hydroxysteroid dehydrogenase, type I; dihydrodiol dehydrogenase 4)	0.050
SLPI	secretory leukocyte peptidase inhibitor	0.049
ITIH4	inter-alpha (globulin) inhibitor H4 (plasma Kallikrein-sensitive glycoprotein)	0.048
ACPP	acid phosphatase, prostate	0.046
ABCC6	ATP-binding cassette, sub-family C (CFTR/MRP), member 6	0.045
ABP1	amiloride binding protein 1 (amine oxidase (copper-containing))	0.044
IL22RA1	interleukin 22 receptor, alpha 1	0.043
CYP2C18	cytochrome P450, family 2, subfamily C, polypeptide 18	0.042
XDH	xanthine dehydrogenase	0.041
ABCC2	ATP-binding cassette, sub-family C (CFTR/MRP), member 2	0.038
HSD17B2	hydroxysteroid (17-beta) dehydrogenase 2	0.037	Human
KLKB1	kallikrein B, plasma (Fletcher factor) 1	0.036
PRSS2	protease, serine, 2 (trypsin 2)	0.034
AKR1B10	aldo-keto reductase family 1, member B10 (aldose reductase)	0.032
ABCG2	ATP-binding cassette, sub-family G (WHITE), member 2	0.032
PON3	paraoxonase 3	0.031
CYP3A5	cytochrome P450, family 3, subfamily A, polypeptide 5	0.031
ANXA13	annexin A13	0.031
HMGCS2	3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial)	0.031
SLC6A12	solute carrier family 6 (neurotransmitter transporter, betaine/GABA), member 12	0.029
SLC5A1	solute carrier family 5 (sodium/glucose cotransporter), member 1	0.029
OTC	ornithine carbamoyltransferase	0.029
ADH6	alcohol dehydrogenase 6 (class V)	0.027
SEC14L2	SEC14-like 2 (S. cerevisiae)	0.027
GJB1	gap junction protein, beta 1, 32kDa	0.027
SERPIND1	serpin peptidase inhibitor, clade D (heparin cofactor), member 1	0.027
APOC3	apolipoprotein C-III	0.027
SGK2	serum/glucocorticoid regulated kinase 2	0.027
GNMT	glycine N-methyltransferase	0.027
HPD	4-hydroxyphenylpyruvate dioxygenase	0.027
ADH1C	alcohol dehydrogenase 1C (class I), gamma polypeptide	0.026
MOSC1	MOCO sulphurase C-terminal domain containing 1	0.025
CRP	C-reactive protein, pentraxin-related	0.025
NR1I2	nuclear receptor subfamily 1, group I, member 2	0.025
CYP2J2	cytochrome P450, family 2, subfamily J, polypeptide 2	0.025
ALDOB	aldolase B, fructose-bisphosphate	0.024
TTR	transthyretin	0.024
TCN1	transcobalamin I (vitamin B12 binding protein, R binder family)	0.024
DDC	dopa decarboxylase (aromatic L-amino acid decarboxylase)	0.023
ITGA7	integrin, alpha 7	0.023
CLCN2	chloride channel 2	0.023
MYOM1	myomesin 1, 185kDa	0.023
ACOX2	acyl-CoA oxidase 2, branched chain	0.023
C4BPB	complement component 4 binding protein, beta	0.023
PIPOX	pipecolic acid oxidase	0.022
SLC7A9	solute carrier family 7 (cationic amino acid transporter, y+ system), member 9	0.022
GSTT1	glutathione S-transferase theta 1	0.022
C8G	complement component 8, gamma polypeptide	0.022
RORC	RAR-related orphan receptor C	0.022
HYAL1	hyaluronoglucosaminidase 1	0.022
C6	complement component 6	0.022
DSG1	desmoglein 1	0.022
ARSE	arylsulfatase E (chondrodysplasia punctata 1)	0.022
ITIH2	inter-alpha (globulin) inhibitor H2	0.022
YBX2	Y box binding protein 2	0.022
CYP4F3	cytochrome P450, family 4, subfamily F, polypeptide 3	0.021
TSPAN1	tetraspanin 1	0.021
NAT2	N-acetyltransferase 2 (arylamine N-acetyltransferase)	0.021
SERPINA6	serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 6	0.021
SPINK1	serine peptidase inhibitor, Kazal type 1	0.020
UGT1A1	UDP glucuronosyltransferase 1 family, polypeptide A1	0.020
CES1	carboxylesterase 1	0.020
IL1F9	interleukin 1 family, member 9	0.020
SPINK5	serine peptidase inhibitor, Kazal type 5	0.020
MAT1A	methionine adenosyltransferase I, alpha	0.020
GPD1	glycerol-3-phosphate dehydrogenase 1 (soluble)	0.020
SLC38A3	solute carrier family 38, member 3	0.020
HSD17B3	hydroxysteroid (17-beta) dehydrogenase 3	0.020
ORM2	orosomucoid 2	0.019
C2orf18	chromosome 2 open reading frame 18	0.019
PLG	plasminogen	0.019
DEFB1	defensin, beta 1	0.019
GPT	glutamic-pyruvate transaminase (alanine aminotransferase)	0.019
CYP2E1	cytochrome P450, family 2, subfamily E, polypeptide 1	0.019
CEL	carboxyl ester lipase (bile salt-stimulated lipase)	0.019
SULT2B1	sulfotransferase family, cytosolic, 2B, member 1	0.019
GPX2	glutathione peroxidase 2 (gastrointestinal)	0.019
OVGP1	oviductal glycoprotein 1, 120kDa	0.019
FABP1	fatty acid binding protein 1, liver	0.018
CDA	cytidine deaminase	0.017
TFR2	transferrin receptor 2	0.017
PRODH2	proline dehydrogenase (oxidase) 2	0.017
FCGBP	Fc fragment of IgG binding protein	0.017
ARG1	arginase, liver	0.017
BBOX1	butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1	0.017
RDH16	retinol dehydrogenase 16 (all-trans)	0.017	Human Mouse
CEACAM1	carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)	0.017
FMO3	flavin containing monooxygenase 3	0.017
APOB	apolipoprotein B (including Ag(x) antigen)	0.016
TM4SF5	transmembrane 4 L six family member 5	0.016
CYP27A1	cytochrome P450, family 27, subfamily A, polypeptide 1	0.016
MTTP	microsomal triglyceride transfer protein	0.016
ENTPD5	ectonucleoside triphosphate diphosphohydrolase 5	0.016
GCKR	glucokinase (hexokinase 4) regulator	0.016
C4BPA	complement component 4 binding protein, alpha	0.016
XPNPEP2	X-prolyl aminopeptidase (aminopeptidase P) 2, membrane-bound	0.016
H2AFY2	H2A histone family, member Y2	0.016
ABCA12	ATP-binding cassette, sub-family A (ABC1), member 12	0.016
HNF4G	hepatocyte nuclear factor 4, gamma	0.016
KLK7	kallikrein-related peptidase 7	0.016
CPB2	carboxypeptidase B2 (plasma)	0.016
AKR1C1	aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase)	0.015
CDSN	corneodesmosin	0.015
NR1H4	nuclear receptor subfamily 1, group H, member 4	0.015
LGALS4	lectin, galactoside-binding, soluble, 4	0.015
S100A14	S100 calcium binding protein A14	0.015
SOAT2	sterol O-acyltransferase 2	0.015
OVOL1	ovo-like 1(Drosophila)	0.015
ALDH8A1	aldehyde dehydrogenase 8 family, member A1	0.015	Mouse
AKR1C3	aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II)	0.015
KCNK5	potassium channel, subfamily K, member 5	0.015
ZNF155	zinc finger protein 155	0.015
CALML5	calmodulin-like 5	0.015
CDHR5	cadherin-related family member 5	0.015
UGT2B4	UDP glucuronosyltransferase 2 family, polypeptide B4	0.015
SULT1E1	sulfotransferase family 1E, estrogen-preferring, member 1	0.015
P2RY13	purinergic receptor P2Y, G-protein coupled, 13	0.015
PDZK1	PDZ domain containing 1	0.015
STARD5	StAR-related lipid transfer (START) domain containing 5	0.015
GYS2	glycogen synthase 2 (liver)	0.015
HTR2B	5-hydroxytryptamine (serotonin) receptor 2B	0.015
FMO4	flavin containing monooxygenase 4	0.015
AOC2	amine oxidase, copper containing 2 (retina-specific)	0.014
SPRR2B	small proline-rich protein 2B	0.014
EHHADH	enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase	0.014
AFP	alpha-fetoprotein	0.014
MYO1A	myosin IA	0.014
RGN	regucalcin (senescence marker protein-30)	0.014
SPRR3	small proline-rich protein 3	0.014
CYP3A4	cytochrome P450, family 3, subfamily A, polypeptide 4	0.014
GLDC	glycine dehydrogenase (decarboxylating)	0.014
BPI	bactericidal/permeability-increasing protein	0.014
EPHX2	epoxide hydrolase 2, cytoplasmic	0.014
RDH5	retinol dehydrogenase 5 (11-cis/9-cis)	0.014	Human
PRSS8	protease, serine, 8	0.014
LILRA2	leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 2	0.014
TM4SF4	transmembrane 4 L six family member 4	0.014
LEAP2	liver expressed antimicrobial peptide 2	0.014
ABCB4	ATP-binding cassette, sub-family B (MDR/TAP), member 4	0.014
BCO2	beta-carotene oxygenase 2	0.014
ABCB11	ATP-binding cassette, sub-family B (MDR/TAP), member 11	0.013
BFSP1	beaded filament structural protein 1, filensin	0.013
HAL	histidine ammonia-lyase	0.013
SERPINF2	serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2	0.013
PIGR	polymeric immunoglobulin receptor	0.013
FHIT	fragile histidine triad gene	0.013
TSPAN8	tetraspanin 8	0.013
PROC	protein C (inactivator of coagulation factors Va and VIIIa)	0.013
LRRC6	leucine rich repeat containing 6	0.013
PRODH	proline dehydrogenase (oxidase) 1	0.013
VNN1	vanin 1	0.013
C9	complement component 9	0.013
ZNF132	zinc finger protein 132	0.013
KPTN	kaptin (actin binding protein)	0.013
FGFBP1	fibroblast growth factor binding protein 1	0.013
HPGD	hydroxyprostaglandin dehydrogenase 15-(NAD)	0.013
EDN3	endothelin 3	0.013
RNF43	ring finger protein 43	0.013
MSTN	myostatin	0.013
ACO1	aconitase 1, soluble	0.013
BHMT	betaine--homocysteine S-methyltransferase	0.013
ACRC	acidic repeat containing	0.013
CYP2B6	cytochrome P450, family 2, subfamily B, polypeptide 6	0.013
FAAH	fatty acid amide hydrolase	0.013
ABCA6	ATP-binding cassette, sub-family A (ABC1), member 6	0.012
PRRG2	proline rich Gla (G-carboxyglutamic acid) 2	0.012
DAPK2	death-associated protein kinase 2	0.012
IL17RB	interleukin 17 receptor B	0.012
TLR5	toll-like receptor 5	0.012
DDX19B	DEAD (Asp-Glu-Ala-As) box polypeptide 19B	0.012
SERPINB4	serpin peptidase inhibitor, clade B (ovalbumin), member 4	0.012
ALDH3A1	aldehyde dehydrogenase 3 family, member A1	0.012
F12	coagulation factor XII (Hageman factor)	0.012
APOM	apolipoprotein M	0.012
VIL1	villin 1	0.012
FAM118A	family with sequence similarity 118, member A	0.012
SLCO1B3	solute carrier organic anion transporter family, member 1B3	0.012
MYOM2	myomesin (M-protein) 2, 165kDa	0.012
TSPYL5	TSPY-like 5	0.012
CNNM4	cyclin M4	0.012
SGCG	sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein)	0.012
OR4C11	olfactory receptor, family 4, subfamily C, member 11	0.012
SNRNP35	small nuclear ribonucleoprotein 35kDa (U11/U12)	0.012
TGM5	transglutaminase 5	0.011
XK	X-linked Kx blood group (McLeod syndrome)	0.011
CRCT1	cysteine-rich C-terminal 1	0.011
CTSL2	cathepsin L2	0.011
TMEM27	transmembrane protein 27	0.011
PIP	prolactin-induced protein	0.011
GSTA3	glutathione S-transferase alpha 3	0.011
SLC16A7	solute carrier family 16, member 7 (monocarboxylic acid transporter 2)	0.011
HDAC11	histone deacetylase 11	0.011
TAF13	TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa	0.011
CDKL1	cyclin-dependent kinase-like 1 (CDC2-related kinase)	0.011
P2RY2	purinergic receptor P2Y, G-protein coupled, 2	0.011
ARL14	ADP-ribosylation factor-like 14	0.011
KCNS3	potassium voltage-gated channel, delayed-rectifier, subfamily S, member 3	0.011
LDHC	lactate dehydrogenase C	0.011
TSKU	tsukushi small leucine rich proteoglycan homolog (Xenopus laevis)	0.011
PLA2G10	phospholipase A2, group X	0.011
PLA2G12B	phospholipase A2, group XIIB	0.011
CNDP1	carnosine dipeptidase 1 (metallopeptidase M20 family)	0.011
PROX1	prospero homeobox 1	0.011
AMDHD1	amidohydrolase domain containing 1	0.011
CYP3A7	cytochrome P450, family 3, subfamily A, polypeptide 7	0.011
CLEC4E	C-type lectin domain family 4, member E	0.011
F10	coagulation factor X	0.011
PLEKHG6	pleckstrin homology domain containing, family G (with RhoGef domain) member 6	0.011
TBX19	T-box 19	0.011
ZNF165	zinc finger protein 165	0.011
DUOX2	dual oxidase 2	0.011
SLC16A10	solute carrier family 16, member 10 (aromatic amino acid transporter)	0.011
NTS	neurotensin	0.011
VIPR1	vasoactive intestinal peptide receptor 1	0.011
CCT6B	chaperonin containing TCP1, subunit 6B (zeta 2)	0.011
GRB14	growth factor receptor-bound protein 14	0.011
SLC20A2	solute carrier family 20 (phosphate transporter), member 2	0.011
CYP2C8	cytochrome P450, family 2, subfamily C, polypeptide 8	0.011
GRAMD1C	GRAM domain containing 1C	0.011
IVL	involucrin	0.011
BAAT	bile acid CoA: amino acid N-acyltransferase (glycine N-choloyltransferase)	0.011
MST1	macrophage stimulating 1 (hepatocyte growth factor-like)	0.011
ZNF643	zinc finger protein 643	0.011
TMEM159	transmembrane protein 159	0.011
C9orf91	chromosome 9 open reading frame 91	0.011
AFM	afamin	0.011
IGJ	immunoglobulin J polypeptide, linker protein for immunoglobulin alpha and mu polypeptides	0.011
FBP1	fructose-1,6-bisphosphatase 1	0.011
AQP7	aquaporin 7	0.010
PIR	pirin (iron-binding nuclear protein)	0.010
SRD5A3	steroid 5 alpha-reductase 3	0.010
CRISP3	cysteine-rich secretory protein 3	0.010
SIRT4	sirtuin 4	0.010
KHK	ketohexokinase (fructokinase)	0.010
FAR2	fatty acyl CoA reductase 2	0.010
AASS	aminoadipate-semialdehyde synthase	0.010
CCDC68	coiled-coil domain containing 68	0.010
MVK	mevalonate kinase	0.010
LECT2	leukocyte cell-derived chemotaxin 2	0.010
SEPP1	selenoprotein P, plasma, 1	0.010
DSC1	desmocollin 1	0.010
LIN7A	lin-7 homolog A (C. elegans)	0.010
SOSTDC1	sclerostin domain containing 1	0.010
CNDP2	CNDP dipeptidase 2 (metallopeptidase M20 family)	0.010
FUT1	fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group)	0.010
TESK2	testis-specific kinase 2	0.010
MPPE1	metallophosphoesterase 1	0.010
KRT23	keratin 23 (histone deacetylase inducible)	0.010
IL13RA2	interleukin 13 receptor, alpha 2	0.010
MUSTN1	musculoskeletal, embryonic nuclear protein 1	0.010
EPHX4	epoxide hydrolase 4	0.010
SLC22A5	solute carrier family 22 (organic cation/carnitine transporter), member 5	0.010