IMP
Process View
negative regulation of integrin activation
Any process that stops, prevents, or reduces the frequency, rate, or extent of integrin activation.
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In addition to gene-name show these genes:
Click on a gene's description to view its network relationships with genes known to be involved in "negative regulation of integrin activation"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| CLASP1 | cytoplasmic linker associated protein 1 | 0.679 | ||
| PTGIR | prostaglandin I2 (prostacyclin) receptor (IP) | 0.540 | Human | |
| TBXA2R | thromboxane A2 receptor | 0.471 | Human | |
| HDAC4 | histone deacetylase 4 | 0.222 | ||
| CENPF | centromere protein F, 350/400kDa (mitosin) | 0.126 | ||
| PRDX4 | peroxiredoxin 4 | 0.060 | ||
| THRAP3 | thyroid hormone receptor associated protein 3 | 0.058 | ||
| RASAL2 | RAS protein activator like 2 | 0.046 | ||
| KIAA0930 | KIAA0930 | 0.043 | ||
| GTSE1 | G-2 and S-phase expressed 1 | 0.043 | ||
| SRGAP2 | SLIT-ROBO Rho GTPase activating protein 2 | 0.039 | ||
| SH3BP4 | SH3-domain binding protein 4 | 0.038 | ||
| KIF15 | kinesin family member 15 | 0.037 | ||
| OSBPL3 | oxysterol binding protein-like 3 | 0.033 | ||
| KLC2 | kinesin light chain 2 | 0.031 | ||
| GHRL | ghrelin/obestatin prepropeptide | 0.031 | ||
| SAMD4A | sterile alpha motif domain containing 4A | 0.031 | ||
| CDCA2 | cell division cycle associated 2 | 0.028 | ||
| SHCBP1 | SHC SH2-domain binding protein 1 | 0.028 | ||
| IRS2 | insulin receptor substrate 2 | 0.027 | ||
| ZNF295 | zinc finger protein 295 | 0.027 | ||
| FAM82A2 | family with sequence similarity 82, member A2 | 0.026 | ||
| FAM64A | family with sequence similarity 64, member A | 0.026 | ||
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide | 0.026 | ||
| PDZD3 | PDZ domain containing 3 | 0.025 | ||
| TIAM1 | T-cell lymphoma invasion and metastasis 1 | 0.025 | ||
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | 0.023 | ||
| KIF23 | kinesin family member 23 | 0.021 | ||
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | 0.020 | ||
| CCNY | cyclin Y | 0.018 | ||
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | 0.016 | ||
| DEPDC1 | DEP domain containing 1 | 0.016 | ||
| CENPE | centromere protein E, 312kDa | 0.015 | ||
| CKAP2L | cytoskeleton associated protein 2-like | 0.015 | ||
| ATF7IP | activating transcription factor 7 interacting protein | 0.014 | ||
| ARHGEF2 | Rho/Rac guanine nucleotide exchange factor (GEF) 2 | 0.013 | ||
| PIK3C3 | phosphoinositide-3-kinase, class 3 | 0.012 | ||
| TROAP | trophinin associated protein (tastin) | 0.012 | ||
| LSR | lipolysis stimulated lipoprotein receptor | 0.011 | ||
| EPB41L3 | erythrocyte membrane protein band 4.1-like 3 | 0.011 | ||
| MDM4 | Mdm4 p53 binding protein homolog (mouse) | 0.011 | ||
| EEA1 | early endosome antigen 1 | 0.011 | ||
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.011 | ||
| TJP2 | tight junction protein 2 (zona occludens 2) | 0.011 | ||
| YAP1 | Yes-associated protein 1 | 0.010 | ||
| RABEP1 | rabaptin, RAB GTPase binding effector protein 1 | 0.010 |