IMP

Process View

Homo sapiens

3 genes annotated in human

alkaloid catabolic process

The chemical reactions and pathways resulting in the breakdown of alkaloids, nitrogen containing natural products not otherwise classified as peptides, nonprotein amino acids, amines, cyanogenic glycosides, glucosinolates, cofactors, phytohormones or primary metabolites (such as purine or pyrimidine bases).

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "alkaloid catabolic process"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "alkaloid catabolic process" (in gray)

Name	Description	Probability	Func Analog Organism
CYP2C9	cytochrome P450, family 2, subfamily C, polypeptide 9	1.000	Human
CYP2A6	cytochrome P450, family 2, subfamily A, polypeptide 6	0.998
CYP3A43	cytochrome P450, family 3, subfamily A, polypeptide 43	0.997	Human
CYP4A11	cytochrome P450, family 4, subfamily A, polypeptide 11	0.991
CYP3A4	cytochrome P450, family 3, subfamily A, polypeptide 4	0.967
CYP2C18	cytochrome P450, family 2, subfamily C, polypeptide 18	0.874	Human
CYP2C19	cytochrome P450, family 2, subfamily C, polypeptide 19	0.767	Human
CYP3A7	cytochrome P450, family 3, subfamily A, polypeptide 7	0.669	Human
CYP2B6	cytochrome P450, family 2, subfamily B, polypeptide 6	0.367	Human
CYP3A5	cytochrome P450, family 3, subfamily A, polypeptide 5	0.324
C8B	complement component 8, beta polypeptide	0.306
CYP4F12	cytochrome P450, family 4, subfamily F, polypeptide 12	0.198
ADH6	alcohol dehydrogenase 6 (class V)	0.188
C6	complement component 6	0.173
MAST1	microtubule associated serine/threonine kinase 1	0.141
DAO	D-amino-acid oxidase	0.120
ALDOB	aldolase B, fructose-bisphosphate	0.115
CFHR4	complement factor H-related 4	0.102
MAT1A	methionine adenosyltransferase I, alpha	0.100
FMO4	flavin containing monooxygenase 4	0.095
F9	coagulation factor IX	0.092
AADAC	arylacetamide deacetylase (esterase)	0.087
PFKFB1	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1	0.079
LAMC3	laminin, gamma 3	0.069
NAT2	N-acetyltransferase 2 (arylamine N-acetyltransferase)	0.068
SULT1B1	sulfotransferase family, cytosolic, 1B, member 1	0.066
CYP1A2	cytochrome P450, family 1, subfamily A, polypeptide 2	0.063
C8A	complement component 8, alpha polypeptide	0.060
A2M	alpha-2-macroglobulin	0.050
CYP2C8	cytochrome P450, family 2, subfamily C, polypeptide 8	0.050	Human
CYP2D6	cytochrome P450, family 2, subfamily D, polypeptide 6	0.048
SULT2A1	sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1	0.046
OTC	ornithine carbamoyltransferase	0.042
CYP4F2	cytochrome P450, family 4, subfamily F, polypeptide 2	0.040
GPLD1	glycosylphosphatidylinositol specific phospholipase D1	0.039
MTTP	microsomal triglyceride transfer protein	0.036
ABCC2	ATP-binding cassette, sub-family C (CFTR/MRP), member 2	0.035
PGRMC1	progesterone receptor membrane component 1	0.035
LGALS4	lectin, galactoside-binding, soluble, 4	0.034
AGXT2	alanine--glyoxylate aminotransferase 2	0.033
CYP2A7	cytochrome P450, family 2, subfamily A, polypeptide 7	0.033	Human
F13B	coagulation factor XIII, B polypeptide	0.032
GBA3	glucosidase, beta, acid 3 (cytosolic)	0.031
NR1I2	nuclear receptor subfamily 1, group I, member 2	0.031
ANXA10	annexin A10	0.030
CYP4F3	cytochrome P450, family 4, subfamily F, polypeptide 3	0.029
SERPINC1	serpin peptidase inhibitor, clade C (antithrombin), member 1	0.029
UGT2B15	UDP glucuronosyltransferase 2 family, polypeptide B15	0.029
APOC4	apolipoprotein C-IV	0.027
GATM	glycine amidinotransferase (L-arginine:glycine amidinotransferase)	0.027
C4BPB	complement component 4 binding protein, beta	0.026
C4BPA	complement component 4 binding protein, alpha	0.026
FGL1	fibrinogen-like 1	0.026
GLYAT	glycine-N-acyltransferase	0.025
LPA	lipoprotein, Lp(a)	0.024
APOC3	apolipoprotein C-III	0.023
MASP2	mannan-binding lectin serine peptidase 2	0.023
MEP1B	meprin A, beta	0.023
ENTPD5	ectonucleoside triphosphate diphosphohydrolase 5	0.022
HRG	histidine-rich glycoprotein	0.022
LRRC31	leucine rich repeat containing 31	0.021
SLC10A1	solute carrier family 10 (sodium/bile acid cotransporter family), member 1	0.021
G6PC	glucose-6-phosphatase, catalytic subunit	0.020
HNF4G	hepatocyte nuclear factor 4, gamma	0.020
PON1	paraoxonase 1	0.020
ACE2	angiotensin I converting enzyme (peptidyl-dipeptidase A) 2	0.020
REG3A	regenerating islet-derived 3 alpha	0.019
CYP2E1	cytochrome P450, family 2, subfamily E, polypeptide 1	0.019	Human
A1CF	APOBEC1 complementation factor	0.019
SLC22A1	solute carrier family 22 (organic cation transporter), member 1	0.019
NR1H4	nuclear receptor subfamily 1, group H, member 4	0.018
SLC2A2	solute carrier family 2 (facilitated glucose transporter), member 2	0.017
XDH	xanthine dehydrogenase	0.017
CPB2	carboxypeptidase B2 (plasma)	0.017
GYS2	glycogen synthase 2 (liver)	0.017
TTPA	tocopherol (alpha) transfer protein	0.017
HGD	homogentisate 1,2-dioxygenase	0.017
CCL16	chemokine (C-C motif) ligand 16	0.016
ABCB11	ATP-binding cassette, sub-family B (MDR/TAP), member 11	0.016
ATP10B	ATPase, class V, type 10B	0.016
UGT2B17	UDP glucuronosyltransferase 2 family, polypeptide B17	0.015
GSTA3	glutathione S-transferase alpha 3	0.015
FETUB	fetuin B	0.015
TEC	tec protein tyrosine kinase	0.014
UGT2B28	UDP glucuronosyltransferase 2 family, polypeptide B28	0.014
GK	glycerol kinase	0.014
RDH13	retinol dehydrogenase 13 (all-trans/9-cis)	0.014
F11	coagulation factor XI	0.014
ABCA5	ATP-binding cassette, sub-family A (ABC1), member 5	0.014
ATOH8	atonal homolog 8 (Drosophila)	0.014
DNASE1L3	deoxyribonuclease I-like 3	0.014
MADCAM1	mucosal vascular addressin cell adhesion molecule 1	0.014
CRP	C-reactive protein, pentraxin-related	0.014
LRRC19	leucine rich repeat containing 19	0.013
MUC3A	mucin 3A, cell surface associated	0.013
C9orf68	chromosome 9 open reading frame 68	0.013
FUT5	fucosyltransferase 5 (alpha (1,3) fucosyltransferase)	0.013
HMGCS2	3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial)	0.013
MIA2	melanoma inhibitory activity 2	0.012
AKR1C4	aldo-keto reductase family 1, member C4 (chlordecone reductase; 3-alpha hydroxysteroid dehydrogenase, type I; dihydrodiol dehydrogenase 4)	0.012
HAL	histidine ammonia-lyase	0.012
CDH17	cadherin 17, LI cadherin (liver-intestine)	0.012
PIK3C2G	phosphoinositide-3-kinase, class 2, gamma polypeptide	0.012
CYP1A1	cytochrome P450, family 1, subfamily A, polypeptide 1	0.012
HHLA2	HERV-H LTR-associating 2	0.012
RAB3D	RAB3D, member RAS oncogene family	0.012
APOE	apolipoprotein E	0.011
KLKB1	kallikrein B, plasma (Fletcher factor) 1	0.011
ZNF717	zinc finger protein 717	0.011
ARG1	arginase, liver	0.011
HIST1H3J	histone cluster 1, H3j	0.011
EPHX2	epoxide hydrolase 2, cytoplasmic	0.011
RNASE6	ribonuclease, RNase A family, k6	0.010
PAH	phenylalanine hydroxylase	0.010
SULT2B1	sulfotransferase family, cytosolic, 2B, member 1	0.010
SULT1E1	sulfotransferase family 1E, estrogen-preferring, member 1	0.010