IMP
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phospholipase c activating dopamine receptor signaling pathway
The series of molecular signals generated as a consequence of a dopamine receptor binding to its physiological ligand, where the pathway proceeds with activation of phospholipase C (PLC) and a subsequent release of inositol trisphosphate (IP3) and diacylglycerol (DAG).
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Click on a gene's description to view its network relationships with genes known to be involved in "phospholipase c activating dopamine receptor signaling pathway"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| EZR | ezrin | 0.907 | ||
| MPDZ | multiple PDZ domain protein | 0.903 | ||
| TBC1D10A | TBC1 domain family, member 10A | 0.901 | ||
| CFTR | cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) | 0.722 | ||
| PAG1 | phosphoprotein associated with glycosphingolipid microdomains 1 | 0.621 | ||
| MAGI3 | membrane associated guanylate kinase, WW and PDZ domain containing 3 | 0.615 | ||
| PTEN | phosphatase and tensin homolog | 0.529 | ||
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.479 | ||
| ADRB2 | adrenergic, beta-2-, receptor, surface | 0.421 | Human | |
| ADORA2A | adenosine A2a receptor | 0.349 | ||
| SLC9A3R1 | solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1 | 0.312 | Mouse | |
| PPP1R9B | protein phosphatase 1, regulatory (inhibitor) subunit 9B | 0.310 | ||
| ARRB1 | arrestin, beta 1 | 0.195 | ||
| SLC6A3 | solute carrier family 6 (neurotransmitter transporter, dopamine), member 3 | 0.151 | ||
| SLC9A3R2 | solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 2 | 0.114 | ||
| P2RY1 | purinergic receptor P2Y, G-protein coupled, 1 | 0.050 | ||
| OR2AG1 | olfactory receptor, family 2, subfamily AG, member 1 | 0.030 | ||
| PLEKHA1 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1 | 0.021 | ||
| NF2 | neurofibromin 2 (merlin) | 0.021 | ||
| PDGFRB | platelet-derived growth factor receptor, beta polypeptide | 0.021 | ||
| MAPK10 | mitogen-activated protein kinase 10 | 0.020 | ||
| PDZK1 | PDZ domain containing 1 | 0.019 | ||
| SSTR3 | somatostatin receptor 3 | 0.018 | ||
| CYP2A6 | cytochrome P450, family 2, subfamily A, polypeptide 6 | 0.015 | ||
| HTR1B | 5-hydroxytryptamine (serotonin) receptor 1B | 0.015 | Human | |
| OPRK1 | opioid receptor, kappa 1 | 0.015 | ||
| GNMT | glycine N-methyltransferase | 0.014 | ||
| GPR6 | G protein-coupled receptor 6 | 0.013 | ||
| DSCAML1 | Down syndrome cell adhesion molecule like 1 | 0.013 | ||
| PPT1 | palmitoyl-protein thioesterase 1 | 0.013 | ||
| GHRHR | growth hormone releasing hormone receptor | 0.012 | ||
| SLC5A5 | solute carrier family 5 (sodium iodide symporter), member 5 | 0.012 | ||
| GRIN1 | glutamate receptor, ionotropic, N-methyl D-aspartate 1 | 0.011 | ||
| TSHR | thyroid stimulating hormone receptor | 0.011 | ||
| P2RY2 | purinergic receptor P2Y, G-protein coupled, 2 | 0.011 | ||
| HTR1D | 5-hydroxytryptamine (serotonin) receptor 1D | 0.010 | Human | |
| SLC9A3 | solute carrier family 9 (sodium/hydrogen exchanger), member 3 | 0.010 | ||
| GRIN2B | glutamate receptor, ionotropic, N-methyl D-aspartate 2B | 0.010 | ||
| GABRA1 | gamma-aminobutyric acid (GABA) A receptor, alpha 1 | 0.010 | ||
| CLCN3 | chloride channel 3 | 0.010 |