IMP
Process View
negative regulation of isotype switching
Any process that stops, prevents, or reduces the frequency, rate or extent of isotype switching.
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In addition to gene-name show these genes:
Click on a gene's description to view its network relationships with genes known to be involved in "negative regulation of isotype switching"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| Cd19 | CD19 antigen | 0.127 | ||
| Il2 | interleukin 2 | 0.103 | ||
| Nfkb2 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100 | 0.082 | ||
| Tnf | tumor necrosis factor | 0.068 | ||
| Ikzf1 | IKAROS family zinc finger 1 | 0.064 | ||
| Igh | immunoglobulin heavy chain complex | 0.063 | ||
| Cd79a | CD79A antigen (immunoglobulin-associated alpha) | 0.054 | ||
| Trp53 | transformation related protein 53 | 0.048 | ||
| Fas | Fas (TNF receptor superfamily member 6) | 0.033 | ||
| Rc3h1 | RING CCCH (C3H) domains 1 | 0.029 | ||
| Pik3cd | phosphatidylinositol 3-kinase catalytic delta polypeptide | 0.028 | ||
| Ttc7 | tetratricopeptide repeat domain 7 | 0.027 | ||
| Rag1 | recombination activating gene 1 | 0.027 | ||
| Ifng | interferon gamma | 0.026 | ||
| Card11 | caspase recruitment domain family, member 11 | 0.025 | ||
| Map3k14 | mitogen-activated protein kinase kinase kinase 14 | 0.021 | ||
| Nfkbia | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.017 | ||
| Tcra | T-cell receptor alpha chain | 0.015 | ||
| Il4 | interleukin 4 | 0.015 | ||
| Gli2 | GLI-Kruppel family member GLI2 | 0.014 | ||
| Cd40 | CD40 antigen | 0.013 | ||
| Pten | phosphatase and tensin homolog | 0.013 | ||
| Il27ra | interleukin 27 receptor, alpha | 0.013 | ||
| Il10 | interleukin 10 | 0.013 | ||
| Smad4 | MAD homolog 4 (Drosophila) | 0.012 | ||
| Pou2af1 | POU domain, class 2, associating factor 1 | 0.012 | ||
| Cd28 | CD28 antigen | 0.011 |