IMP

Process View

Mus musculus

6 genes annotated in mouse

plasma lipoprotein particle remodeling

The acquisition, loss or modification of a protein or lipid within a plasma lipoprotein particle, including the hydrolysis of triglyceride by hepatic lipase, with the subsequent loss of free fatty acid, and the esterification of cholesterol by phosphatidylcholine-sterol O-acyltransferase (lecithin cholesterol acyltransferase; LCAT).

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Known genes in the process in mouse Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "plasma lipoprotein particle remodeling"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "plasma lipoprotein particle remodeling" (in gray)

Name	Description	Probability	Func Analog Organism
Apoa1	apolipoprotein A-I	1.000	Human Mouse
Abca1	ATP-binding cassette, sub-family A (ABC1), member 1	0.994
Apoe	apolipoprotein E	0.985
Apob	apolipoprotein B	0.830	Human
Ahsg	alpha-2-HS-glycoprotein	0.494
Apoa2	apolipoprotein A-II	0.481
Npc1	Niemann Pick type C1	0.452
F2	coagulation factor II	0.412
Ldlr	low density lipoprotein receptor	0.389
Apom	apolipoprotein M	0.347
Aldob	aldolase B, fructose-bisphosphate	0.332
Gcgr	glucagon receptor	0.315
Dmgdh	dimethylglycine dehydrogenase precursor	0.242
Ambp	alpha 1 microglobulin/bikunin	0.215
Serpinf2	serine (or cysteine) peptidase inhibitor, clade F, member 2	0.212
Plg	plasminogen	0.208
Nos3	nitric oxide synthase 3, endothelial cell	0.208
Prodh2	proline dehydrogenase (oxidase) 2	0.172
Fgb	fibrinogen beta chain	0.169
Cyp2d26	cytochrome P450, family 2, subfamily d, polypeptide 26	0.157
Apoa4	apolipoprotein A-IV	0.157	Mouse
Apoc3	apolipoprotein C-III	0.150
Prnp	prion protein	0.125
Hnf4a	hepatic nuclear factor 4, alpha	0.113
Agt	angiotensinogen (serpin peptidase inhibitor, clade A, member 8)	0.097
Cyp2c70	cytochrome P450, family 2, subfamily c, polypeptide 70	0.094
Asgr2	asialoglycoprotein receptor 2	0.094
Slc27a5	solute carrier family 27 (fatty acid transporter), member 5	0.091
Azgp1	alpha-2-glycoprotein 1, zinc	0.090
F12	coagulation factor XII (Hageman factor)	0.089
Lyz2	lysozyme 2	0.088
Cyp2d10	cytochrome P450, family 2, subfamily d, polypeptide 10	0.087
Lrp1	low density lipoprotein receptor-related protein 1	0.087
Scarb1	scavenger receptor class B, member 1	0.073
Serpinc1	serine (or cysteine) peptidase inhibitor, clade C (antithrombin), member 1	0.071
Lpl	lipoprotein lipase	0.065
Mt1	metallothionein 1	0.057
C3	complement component 3	0.057
Abcg1	ATP-binding cassette, sub-family G (WHITE), member 1	0.054
Fgg	fibrinogen gamma chain	0.052
Cdhr5	cadherin-related family member 5	0.041
Mbl2	mannose-binding lectin (protein C) 2	0.039
1300017J02Rik	RIKEN cDNA 1300017J02 gene	0.038
Apoa5	apolipoprotein A-V	0.038
Scd1	stearoyl-Coenzyme A desaturase 1	0.036
Pklr	pyruvate kinase liver and red blood cell	0.036
Mt2	metallothionein 2	0.035
Hgfac	hepatocyte growth factor activator	0.034
Hgd	homogentisate 1, 2-dioxygenase	0.032
Abhd5	abhydrolase domain containing 5	0.032
Spp2	secreted phosphoprotein 2	0.030
Gc	group specific component	0.030
Gulo	gulonolactone (L-) oxidase	0.030
Serpind1	serine (or cysteine) peptidase inhibitor, clade D, member 1	0.030
Apoc4	apolipoprotein C-IV	0.029
Ghr	growth hormone receptor	0.029
Cfi	complement component factor i	0.029
Trfr2	transferrin receptor 2	0.028
Pten	phosphatase and tensin homolog	0.026
Serpina10	serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10	0.025
Efemp2	epidermal growth factor-containing fibulin-like extracellular matrix protein 2	0.025
Pdzk1	PDZ domain containing 1	0.024
Pltp	phospholipid transfer protein	0.024
Gjb2	gap junction protein, beta 2	0.024
Cfh	complement component factor h	0.023
Hsd11b1	hydroxysteroid 11-beta dehydrogenase 1	0.022
Angptl4	angiopoietin-like 4	0.022
Hpn	hepsin	0.021
Foxa3	forkhead box A3	0.021
Proc	protein C	0.021
Apof	apolipoprotein F	0.020
Lcat	lecithin cholesterol acyltransferase	0.020	Human
Lpin1	lipin 1	0.020
Timp3	tissue inhibitor of metalloproteinase 3	0.020
Hsd17b2	hydroxysteroid (17-beta) dehydrogenase 2	0.020
Lgmn	legumain	0.019
Sdsl	serine dehydratase-like	0.018
Slc12a6	solute carrier family 12, member 6	0.018
Pparg	peroxisome proliferator activated receptor gamma	0.017
Klf15	Kruppel-like factor 15	0.017
Slc6a13	solute carrier family 6 (neurotransmitter transporter, GABA), member 13	0.017
Pla2g12b	phospholipase A2, group XIIB	0.016
Nfe2l2	nuclear factor, erythroid derived 2, like 2	0.015
Pzp	pregnancy zone protein	0.014
Nr1h3	nuclear receptor subfamily 1, group H, member 3	0.013
Apoh	apolipoprotein H	0.013
Mst1	macrophage stimulating 1 (hepatocyte growth factor-like)	0.013
Fabp1	fatty acid binding protein 1, liver	0.012
Qprt	quinolinate phosphoribosyltransferase	0.012
Ces1c	carboxylesterase 1C	0.012
Timd2	T-cell immunoglobulin and mucin domain containing 2	0.012
Agtr1a	angiotensin II receptor, type 1a	0.012
Cav1	caveolin 1, caveolae protein	0.012
Fga	fibrinogen alpha chain	0.012
Hpx	hemopexin	0.012
Golt1a	golgi transport 1 homolog A (S. cerevisiae)	0.012
Slc10a1	solute carrier family 10 (sodium/bile acid cotransporter family), member 1	0.012
Abcb4	ATP-binding cassette, sub-family B (MDR/TAP), member 4	0.012
Cd302	CD302 antigen	0.011
Agxt	alanine-glyoxylate aminotransferase	0.011
Aadat	aminoadipate aminotransferase	0.011
Itih3	inter-alpha trypsin inhibitor, heavy chain 3	0.011
Rab17	RAB17, member RAS oncogene family	0.011
Abcg5	ATP-binding cassette, sub-family G (WHITE), member 5	0.011
Soat2	sterol O-acyltransferase 2	0.011
Dusp1	dual specificity phosphatase 1	0.011
Slc2a4	solute carrier family 2 (facilitated glucose transporter), member 4	0.011
Mylip	myosin regulatory light chain interacting protein	0.010
Angptl3	angiopoietin-like 3	0.010
Cebpb	CCAAT/enhancer binding protein (C/EBP), beta	0.010
Itih1	inter-alpha trypsin inhibitor, heavy chain 1	0.010
Apoc2	apolipoprotein C-II	0.010