IMP

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Rattus norvegicus

2 genes annotated in rat

regulation of platelet activation

Any process that modulates the rate or frequency of platelet activation. Platelet activation is a series of progressive, overlapping events triggered by exposure of the platelets to subendothelial tissue.

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Known genes in the process in rat Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "regulation of platelet activation"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "regulation of platelet activation" (in gray)

Name	Description	Probability	Func Analog Organism
Cd44	Cd44 molecule	0.110
Gja1	gap junction protein, alpha 1	0.079
Icam1	intercellular adhesion molecule 1	0.070
Ddr2	discoidin domain receptor tyrosine kinase 2	0.061
Olr1500	olfactory receptor 1500	0.054
Fgr	Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog	0.052
Bst1	bone marrow stromal cell antigen 1	0.051
Ncan	neurocan	0.049
Ccl4	chemokine (C-C motif) ligand 4	0.048
Axl	Axl receptor tyrosine kinase	0.044
Itgb7	integrin, beta 7	0.042
Casp1	caspase 1	0.040
Rorb	RAR-related orphan receptor B	0.040
Edn1	endothelin 1	0.039
Inpp5d	inositol polyphosphate-5-phosphatase D	0.038
Ptafr	platelet-activating factor receptor	0.038
Ms4a2	membrane-spanning 4-domains, subfamily A, member 2 (Fc fragment of IgE, high affinity I, receptor for; beta polypeptide)	0.038
Arl11	ADP-ribosylation factor-like 11	0.037
Slc6a3	solute carrier family 6 (neurotransmitter transporter, dopamine), member 3	0.037
Phkg1	phosphorylase kinase, gamma 1	0.034
Pmp22	peripheral myelin protein 22	0.034
Pla1a	phospholipase A1 member A	0.034
Fgf14	fibroblast growth factor 14	0.033
Plau	plasminogen activator, urokinase	0.033
Ccl3	chemokine (C-C motif) ligand 3	0.032
Gabrg3	gamma-aminobutyric acid (GABA) A receptor, gamma 3	0.032
Colec12	collectin sub-family member 12	0.030
Cma1	chymase 1, mast cell	0.030
Gpc3	glypican 3	0.030
Cyp11a1	cytochrome P450, family 11, subfamily a, polypeptide 1	0.029
Gna15	guanine nucleotide binding protein, alpha 15	0.029
Fn1	fibronectin 1	0.029
Hck	hemopoietic cell kinase	0.028
Rassf5	Ras association (RalGDS/AF-6) domain family member 5	0.027
Gucy2f	guanylate cyclase 2F	0.027
Atp2b4	ATPase, Ca++ transporting, plasma membrane 4	0.026
Cd37	CD37 molecule	0.026
Bgn	biglycan	0.026
Wipf1	WAS/WASL interacting protein family, member 1	0.026
Kcnq2	potassium voltage-gated channel, KQT-like subfamily, member 2	0.026
Fshb	follicle stimulating hormone, beta polypeptide	0.026
Pecam1	platelet/endothelial cell adhesion molecule 1	0.025
Aebp1	AE binding protein 1	0.025
Gja4	gap junction protein, alpha 4	0.025
Arhgdib	Rho, GDP dissociation inhibitor (GDI) beta	0.024
Pth	parathyroid hormone	0.024
Cd83	CD83 molecule	0.024
Ltbp3	latent transforming growth factor beta binding protein 3	0.023
Agtr1a	angiotensin II receptor, type 1a	0.023
Vcan	versican	0.023
Runx1	runt-related transcription factor 1	0.023
Mmp12	matrix metallopeptidase 12	0.023
Ednrb	endothelin receptor type B	0.023
Gpr88	G-protein coupled receptor 88	0.023
Homer3	homer homolog 3 (Drosophila)	0.023
RGD1564664	similar to LOC387763 protein	0.022
Slc2a3	solute carrier family 2 (facilitated glucose transporter), member 3	0.022
Slc1a3	solute carrier family 1 (glial high affinity glutamate transporter), member 3	0.022
Il7	interleukin 7	0.022
Il1rap	interleukin 1 receptor accessory protein	0.022
Cd247	Cd247 molecule	0.021
Slc2a13	solute carrier family 2 (facilitated glucose transporter), member 13	0.021
Gria4	glutamate receptor, ionotrophic, AMPA 4	0.021
Ly86	lymphocyte antigen 86	0.021
Tpsb2	tryptase beta 2	0.021
Crhbp	corticotropin releasing hormone binding protein	0.021
Csrnp2	cysteine-serine-rich nuclear protein 2	0.020
Fat3	FAT tumor suppressor homolog 3 (Drosophila)	0.020
Npy5r	neuropeptide Y receptor Y5	0.020
Mmp14	matrix metallopeptidase 14 (membrane-inserted)	0.020
Ctrc	chymotrypsin C (caldecrin)	0.020
Kcnk13	potassium channel, subfamily K, member 13	0.020
Cd5	Cd5 molecule	0.020
C5ar1	complement component 5a receptor 1	0.020
Ripk3	receptor-interacting serine-threonine kinase 3	0.020
LOC60591	calcium-activated potassium channel beta subunit	0.020
Olr287	olfactory receptor 287	0.020
Pla2g4a	phospholipase A2, group IVA (cytosolic, calcium-dependent)	0.020
Adcyap1r1	adenylate cyclase activating polypeptide 1 receptor 1	0.020
Dock8	dedicator of cytokinesis 8	0.020
Fgf7	fibroblast growth factor 7	0.019
Lst1	leukocyte specific transcript 1	0.019
Kalrn	kalirin, RhoGEF kinase	0.019
Lamc1	laminin, gamma 1	0.019
Prrx1	paired related homeobox 1	0.019
Il6	interleukin 6	0.019
Olr1523	olfactory receptor 1523	0.019
Gad2	glutamate decarboxylase 2	0.019
Adam17	ADAM metallopeptidase domain 17	0.019
Mmp9	matrix metallopeptidase 9	0.019
Rhoj	ras homolog gene family, member J	0.019
Athl1	ATH1, acid trehalase-like 1 (yeast)	0.019
Tal1	T-cell acute lymphocytic leukemia 1	0.018
Cxcl2	chemokine (C-X-C motif) ligand 2	0.018
Cryge	crystallin, gamma E	0.018
Il1b	interleukin 1 beta	0.018
Arnt2	aryl hydrocarbon receptor nuclear translocator 2	0.018
S1pr2	sphingosine-1-phosphate receptor 2	0.018
Sla	src-like adaptor	0.018
A3galt2	alpha 1,3-galactosyltransferase 2	0.018
Prl3d1	Prolactin family 3, subfamily d, member 1	0.018
Il8rb	interleukin 8 receptor, beta	0.018
Tacr2	tachykinin receptor 2	0.018
Aldh1a2	aldehyde dehydrogenase 1 family, member A2	0.018
Svs1	seminal vesicle secretory protein 1	0.018
Arhgap25	Rho GTPase activating protein 25	0.018
Uhmk1	U2AF homology motif (UHM) kinase 1	0.018
Fstl1	follistatin-like 1	0.018
Rup2	urinary protein 2	0.018
Olr1	oxidized low density lipoprotein (lectin-like) receptor 1	0.018
Synpo	synaptopodin	0.018
Engase	endo-beta-N-acetylglucosaminidase	0.017
Tnfsf4	tumor necrosis factor (ligand) superfamily, member 4	0.017
Ptpn7	protein tyrosine phosphatase, non-receptor type 7	0.017
Il1r1	interleukin 1 receptor, type I	0.017
Folh1	folate hydrolase 1	0.017
Acp5	acid phosphatase 5, tartrate resistant	0.017
Gfap	glial fibrillary acidic protein	0.017
Cmtm2a	CKLF-like MARVEL transmembrane domain containing 2A	0.017
Chia	chitinase, acidic	0.017
C1qtnf6	C1q and tumor necrosis factor related protein 6	0.017
Slc7a2	solute carrier family 7 (cationic amino acid transporter, y+ system), member 2	0.017
Bok	BCL2-related ovarian killer	0.017
Hes2	hairy and enhancer of split 2 (Drosophila)	0.017
Grifin	galectin-related inter-fiber protein	0.017
Sirpa	signal-regulatory protein alpha	0.017
Alb	albumin	0.016
Vcsa1	variable coding sequence A1	0.016
LOC686432	hypothetical protein LOC686432	0.016
Klk1c10	T-kininogenase	0.016
Map3k8	mitogen-activated protein kinase kinase kinase 8	0.016
Renbp	renin binding protein	0.016
LOC100364212	heterogeneous nuclear ribonucleoprotein K-like	0.016
Igfbp5	insulin-like growth factor binding protein 5	0.016
Accn2	amiloride-sensitive cation channel 2, neuronal	0.016
Itpr2	inositol 1,4,5-triphosphate receptor, type 2	0.016
Prg2	proteoglycan 2, bone marrow	0.016
Alox5	arachidonate 5-lipoxygenase	0.016
Slco6b1	solute carrier organic anion transporter family, member 6b1	0.016
Adarb2	adenosine deaminase, RNA-specific, B2	0.015
Slc22a2	solute carrier family 22 (organic cation transporter), member 2	0.015
Thbd	thrombomodulin	0.015
Adam5	a disintegrin and metallopeptidase domain 5	0.015
Cfp	complement factor properdin	0.015
P2ry6	pyrimidinergic receptor P2Y, G-protein coupled, 6	0.015
Cd8b	CD8b molecule	0.015
Hdgfl1	hepatoma derived growth factor-like 1	0.015
Gpr6	G protein-coupled receptor 6	0.015
Hmox1	heme oxygenase (decycling) 1	0.015
Sfrp4	secreted frizzled-related protein 4	0.015
Grik3	glutamate receptor, ionotropic, kainate 3	0.015
Nras	neuroblastoma ras oncogene	0.015
Lsm6	LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae)	0.015
Tlr7	toll-like receptor 7	0.015
Ace	angiotensin I converting enzyme (peptidyl-dipeptidase A) 1	0.015
Vcam1	vascular cell adhesion molecule 1	0.015
Fgf2	fibroblast growth factor 2	0.015
Olr416	olfactory receptor 416	0.015
Myo1a	myosin IA	0.015
Lama2	laminin, alpha 2	0.015
Ramp1	receptor (G protein-coupled) activity modifying protein 1	0.015
Gjb5	gap junction protein, beta 5	0.015
Chrna1	cholinergic receptor, nicotinic, alpha 1 (muscle)	0.015
Ier5	immediate early response 5	0.015
Cxcl10	chemokine (C-X-C motif) ligand 10	0.014
Gm2a	GM2 ganglioside activator	0.014
Lyn	v-yes-1 Yamaguchi sarcoma viral related oncogene homolog	0.014	Mouse
Cckar	cholecystokinin A receptor	0.014
Defb22	defensin beta 22	0.014
Plod2	procollagen lysine, 2-oxoglutarate 5-dioxygenase 2	0.014
Angpt2	angiopoietin 2	0.014
F13a1	coagulation factor XIII, A1 polypeptide	0.014
LOC24906	RoBo-1	0.014
Slc24a6	solute carrier family 24 (sodium/potassium/calcium exchanger), member 6	0.014
Elk3	ELK3, ETS-domain protein	0.014
Mca32	mast cell antigen 32	0.014
Olr825	olfactory receptor 825	0.014
Ptger1	prostaglandin E receptor 1 (subtype EP1)	0.014
Cpa3	carboxypeptidase A3, mast cell	0.014
Il1rl2	interleukin 1 receptor-like 2	0.014
Aqp4	aquaporin 4	0.014
Trpc4	transient receptor potential cation channel, subfamily C, member 4	0.014
Tnfsf13	tumor necrosis factor (ligand) superfamily, member 13	0.014
Vwf	von Willebrand factor	0.014
Evi2a	ecotropic viral integration site 2A	0.014
Svs3a	seminal vesicle secretory protein 3A	0.014
Fgfr2	fibroblast growth factor receptor 2	0.014
LOC360479	similar to hypothetical protein	0.014
Vom1r90	vomeronasal 1 receptor 90	0.014
Sema3a	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A	0.014
Ccr5	chemokine (C-C motif) receptor 5	0.013
Rgs14	regulator of G-protein signaling 14	0.013
Rin1	Ras and Rab interactor 1	0.013
Kcng3	potassium voltage-gated channel, subfamily G, member 3	0.013
Cyp21a1	cytochrome P450, family 21, subfamily a, polypeptide 1	0.013
Lrp1	low density lipoprotein-related protein 1 (alpha-2-macroglobulin receptor)	0.013
Pmfbp1	polyamine modulated factor 1 binding protein 1	0.013
Csk	c-src tyrosine kinase	0.013
Trhr2	thyrotropin releasing hormone receptor 2	0.013
Jak2	Janus kinase 2	0.013
Apol3	apolipoprotein L, 3	0.013
Tlr4	toll-like receptor 4	0.013	Mouse
Dpysl2	dihydropyrimidinase-like 2	0.013
Calcb	calcitonin-related polypeptide, beta	0.013
Ar	androgen receptor	0.013
Cmklr1	chemokine-like receptor 1	0.013
Kcnj4	potassium inwardly-rectifying channel, subfamily J, member 4	0.013
Cst8	cystatin 8 (cystatin-related epididymal specific)	0.013
RGD1562717	similar to ABI gene family, member 3 (NESH) binding protein	0.013
Spon1	spondin 1, extracellular matrix protein	0.013
Mmp13	matrix metallopeptidase 13	0.013
Pla2g2a	phospholipase A2, group IIA (platelets, synovial fluid)	0.013
Ucp1	uncoupling protein 1 (mitochondrial, proton carrier)	0.013
Pdc	phosducin	0.013
Dlx5	distal-less homeobox 5	0.013
Wdr31	WD repeat domain 31	0.013
Sstr5	somatostatin receptor 5	0.013
Kcnab1	potassium voltage-gated channel, shaker-related subfamily, beta member 1	0.013
Cga	glycoprotein hormones, alpha polypeptide	0.013
Cnp	2',3'-cyclic nucleotide 3' phosphodiesterase	0.013
Vom2r27	vomeronasal 2 receptor, 27	0.013
C1qtnf5	C1q and tumor necrosis factor related protein 5	0.013
Tacr3	tachykinin receptor 3	0.012
Gabra5	gamma-aminobutyric acid (GABA) A receptor, alpha 5	0.012
Slc6a2	solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2	0.012
Prm2	protamine 2	0.012
Slc38a5	solute carrier family 38, member 5	0.012
Scn4a	sodium channel, voltage-gated, type IV, alpha subunit	0.012
Mapk4	mitogen-activated protein kinase 4	0.012
Ibsp	integrin-binding sialoprotein	0.012
Tlr2	toll-like receptor 2	0.012
Cxcl13	chemokine (C-X-C motif) ligand 13	0.012
Cacna1a	calcium channel, voltage-dependent, P/Q type, alpha 1A subunit	0.012
Csf2rb	colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)	0.012
RGD1564327	similar to integrin alpha 8	0.012
Chrnb2	cholinergic receptor, nicotinic, beta 2 (neuronal)	0.012
Gpc2	glypican 2	0.012
Dbc1	deleted in bladder cancer 1 (human)	0.012
Gpr12	G protein-coupled receptor 12	0.012
Bcl2	B-cell CLL/lymphoma 2	0.012
Cxcl1	chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)	0.012
Cxcl6	chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2)	0.012
Tirap	toll-interleukin 1 receptor (TIR) domain-containing adaptor protein	0.012
Bmpr1a	bone morphogenetic protein receptor, type IA	0.012
Prkca	protein kinase C, alpha	0.012
Adora2a	adenosine A2a receptor	0.012
Hdac7	histone deacetylase 7	0.012
Erbb4	v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)	0.012
Csf3	colony stimulating factor 3 (granulocyte)	0.012
Ttc36	tetratricopeptide repeat domain 36	0.012
Add3	adducin 3 (gamma)	0.012
Rgs8	regulator of G-protein signaling 8	0.012
Ptgs1	prostaglandin-endoperoxide synthase 1	0.012
Fbln1	fibulin 1	0.012
Reg3a	regenerating islet-derived 3 alpha	0.011
Duoxa1	dual oxidase maturation factor 1	0.011
Il2ra	interleukin 2 receptor, alpha	0.011
Slco1a5	solute carrier organic anion transporter family, member 1a5	0.011
Lep	leptin	0.011
Kcnc2	potassium voltage gated channel, Shaw-related subfamily, member 2	0.011
Vdr	vitamin D (1,25- dihydroxyvitamin D3) receptor	0.011
Junb	jun B proto-oncogene	0.011
Vav1	vav 1 guanine nucleotide exchange factor	0.011
Fam38a	family with sequence similarity 38, member A	0.011
Itgam	integrin, alpha M	0.011
Ugt8	UDP glycosyltransferase 8	0.011
Sh2b2	SH2B adaptor protein 2	0.011
Egr3	early growth response 3	0.011
Cd28	Cd28 molecule	0.011
Sod3	superoxide dismutase 3, extracellular	0.011
Aif1	allograft inflammatory factor 1	0.011
Ltbp1	latent transforming growth factor beta binding protein 1	0.011
Shank1	SH3 and multiple ankyrin repeat domains 1	0.011
Rgs9	regulator of G-protein signaling 9	0.011
Tas2r105	taste receptor, type 2, member 105	0.011
Ccr2	chemokine (C-C motif) receptor 2	0.011
Mcpt1	mast cell protease 1	0.011
Cyp1b1	cytochrome P450, family 1, subfamily b, polypeptide 1	0.011
Reg1a	regenerating islet-derived 1 alpha	0.011
Lhx5	LIM homeobox 5	0.011
Cdh17	cadherin 17	0.011
Ccdc3	coiled-coil domain containing 3	0.011
Sult5a1	sulfotransferase family 5A, member 1	0.011
Figf	c-fos induced growth factor	0.011
Fgl2	fibrinogen-like 2	0.011
Slc34a1	solute carrier family 34 (sodium phosphate), member 1	0.011
Casp12	caspase 12	0.011
Cxcr4	chemokine (C-X-C motif) receptor 4	0.011
Dmkn	dermokine	0.011
Pdgfra	platelet derived growth factor receptor, alpha polypeptide	0.011	Human
Ifna1	interferon-alpha 1	0.011
Pcdhb9	protocadherin beta 9	0.011
Prp15	proline-rich protein 15	0.011
Cyb5r1	cytochrome b5 reductase 1	0.011
Adm	adrenomedullin	0.011
Klrb1c	killer cell lectin-like receptor subfamily B member 1C	0.011
Crygf	crystallin, gamma F	0.011
RGD1307396	similar to RIKEN cDNA 6330406I15	0.011
B3gat1	beta-1,3-glucuronyltransferase 1 (glucuronosyltransferase P)	0.011
Il12b	interleukin 12B	0.011
Kcna5	potassium voltage-gated channel, shaker-related subfamily, member 5	0.011
Slc22a13	solute carrier family 22 (organic anion transporter), member 13	0.011
Cacna1c	calcium channel, voltage-dependent, L type, alpha 1C subunit	0.011
Syt8	synaptotagmin VIII	0.011
Pik3cd	phosphoinositide-3-kinase, catalytic, delta polypeptide	0.011
Tas2r126	taste receptor, type 2, member 126	0.011
Ptk7	PTK7 protein tyrosine kinase 7	0.011
Slpi	secretory leukocyte peptidase inhibitor	0.010
Serpina3n	serine (or cysteine) peptidase inhibitor, clade A, member 3N	0.010
Cdc7	cell division cycle 7 homolog (S. cerevisiae)	0.010
Npy1r	neuropeptide Y receptor Y1	0.010
Np4	defensin NP-4 precursor	0.010
Alox5ap	arachidonate 5-lipoxygenase activating protein	0.010
Tmem106a	transmembrane protein 106A	0.010
Adam2	ADAM metallopeptidase domain 2	0.010
Tnni1	troponin I type 1 (skeletal, slow)	0.010
Hrasls5	HRAS-like suppressor family, member 5	0.010
RT1-Db1	RT1 class II, locus Db1	0.010
Slc6a17	solute carrier family 6 (neurotransmitter transporter), member 17	0.010
Mapkapk3	mitogen-activated protein kinase-activated protein kinase 3	0.010
Fmod	fibromodulin	0.010
Nrp2	neuropilin 2	0.010
Grin3a	glutamate receptor, ionotropic, N-methyl-D-aspartate 3A	0.010
Slc7a3	solute carrier family 7 (cationic amino acid transporter, y+ system), member 3	0.010
Dusp7	dual specificity phosphatase 7	0.010
Dab2	disabled homolog 2 (Drosophila)	0.010
Fam70b	family with sequence similarity 70, member B	0.010
Chrna6	cholinergic receptor, nicotinic, alpha 6	0.010
Neurod2	neurogenic differentiation 2	0.010
Pik3ap1	phosphoinositide-3-kinase adaptor protein 1	0.010
Anxa4	annexin A4	0.010
Egr2	early growth response 2	0.010
Cxcr5	chemokine (C-X-C motif) receptor 5	0.010
Grm6	glutamate receptor, metabotropic 6	0.010
Cdkn1c	cyclin-dependent kinase inhibitor 1C	0.010
Hspa1l	heat shock protein 1-like	0.010