IMP
Process View
The network for 'eosinophil activation involved in immune response' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.
Multiple Organisms
eosinophil activation involved in immune response
The change in morphology and behavior of a eosinophil resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor, leading to the initiation or perpetuation of an immune response.
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| CCR5 | chemokine (C-C motif) receptor 5 | 1.000 | |
| CCL4 | chemokine (C-C motif) ligand 4 | 1.000 | |
| CXCL9 | chemokine (C-X-C motif) ligand 9 | 0.999 | |
| CCL5 | chemokine (C-C motif) ligand 5 | 0.997 | |
| CCL8 | chemokine (C-C motif) ligand 8 | 0.996 | |
| IL1B | interleukin 1, beta | 0.990 | |
| IL8 | interleukin 8 | 0.989 | |
| CCR7 | chemokine (C-C motif) receptor 7 | 0.977 | |
| CCL18 | chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated) | 0.975 | |
| CXCL10 | chemokine (C-X-C motif) ligand 10 | 0.965 | |
| CCL22 | chemokine (C-C motif) ligand 22 | 0.930 | |
| CXCL11 | chemokine (C-X-C motif) ligand 11 | 0.928 | |
| CXCL2 | chemokine (C-X-C motif) ligand 2 | 0.907 | |
| IFNG | interferon, gamma | 0.898 | |
| CCL2 | chemokine (C-C motif) ligand 2 | 0.892 | |
| IL6 | interleukin 6 (interferon, beta 2) | 0.887 | |
| CCR1 | chemokine (C-C motif) receptor 1 | 0.886 | |
| CXCL1 | chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) | 0.871 | |
| CCL13 | chemokine (C-C motif) ligand 13 | 0.855 | |
| IL2RB | interleukin 2 receptor, beta | 0.855 | |
| CXCL3 | chemokine (C-X-C motif) ligand 3 | 0.840 | |
| CCL19 | chemokine (C-C motif) ligand 19 | 0.736 | |
| CCL3 | chemokine (C-C motif) ligand 3 | 0.733 | |
| CCL7 | chemokine (C-C motif) ligand 7 | 0.729 | |
| ANKRD27 | ankyrin repeat domain 27 (VPS9 domain) | 0.719 | |
| IL10 | interleukin 10 | 0.692 | |
| TNFRSF9 | tumor necrosis factor receptor superfamily, member 9 | 0.684 | |
| CXCL13 | chemokine (C-X-C motif) ligand 13 | 0.684 | |
| IDE | insulin-degrading enzyme | 0.662 | |
| TNF | tumor necrosis factor | 0.638 | |
| IL7R | interleukin 7 receptor | 0.628 | |
| CCR4 | chemokine (C-C motif) receptor 4 | 0.612 | |
| CD83 | CD83 molecule | 0.595 | |
| CXCR6 | chemokine (C-X-C motif) receptor 6 | 0.548 | |
| ICAM1 | intercellular adhesion molecule 1 | 0.483 | |
| RGS1 | regulator of G-protein signaling 1 | 0.475 | |
| SLAMF7 | SLAM family member 7 | 0.459 | |
| CCL20 | chemokine (C-C motif) ligand 20 | 0.427 | |
| DPP4 | dipeptidyl-peptidase 4 | 0.407 | |
| CXCL6 | chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2) | 0.402 | |
| FPR3 | formyl peptide receptor 3 | 0.386 | |
| IL1RN | interleukin 1 receptor antagonist | 0.325 | |
| SELE | selectin E | 0.312 | |
| IL10RA | interleukin 10 receptor, alpha | 0.310 | |
| MMP12 | matrix metallopeptidase 12 (macrophage elastase) | 0.299 | |
| IL2RG | interleukin 2 receptor, gamma | 0.289 | |
| SIGLEC1 | sialic acid binding Ig-like lectin 1, sialoadhesin | 0.286 | |
| CD86 | CD86 molecule | 0.283 | |
| CXCL5 | chemokine (C-X-C motif) ligand 5 | 0.275 | |
| AGFG1 | ArfGAP with FG repeats 1 | 0.274 | |
| KLRD1 | killer cell lectin-like receptor subfamily D, member 1 | 0.261 | |
| IL18RAP | interleukin 18 receptor accessory protein | 0.258 | |
| AKT2 | v-akt murine thymoma viral oncogene homolog 2 | 0.248 | |
| CH25H | cholesterol 25-hydroxylase | 0.239 | |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | 0.230 | |
| VCAM1 | vascular cell adhesion molecule 1 | 0.219 | |
| STAT4 | signal transducer and activator of transcription 4 | 0.217 | |
| LAMP3 | lysosomal-associated membrane protein 3 | 0.198 | |
| UBD | ubiquitin D | 0.185 | |
| GZMB | granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) | 0.185 | |
| ADAMDEC1 | ADAM-like, decysin 1 | 0.184 | |
| IRF4 | interferon regulatory factor 4 | 0.178 | |
| IDO1 | indoleamine 2,3-dioxygenase 1 | 0.173 | |
| LTA | lymphotoxin alpha (TNF superfamily, member 1) | 0.171 | |
| IL1R2 | interleukin 1 receptor, type II | 0.170 | |
| TFEC | transcription factor EC | 0.143 | |
| SLAMF1 | signaling lymphocytic activation molecule family member 1 | 0.143 | |
| CD80 | CD80 molecule | 0.142 | |
| CD69 | CD69 molecule | 0.138 | |
| IL2RA | interleukin 2 receptor, alpha | 0.137 | |
| IL12B | interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40) | 0.133 | |
| CCL11 | chemokine (C-C motif) ligand 11 | 0.132 | |
| BCL2A1 | BCL2-related protein A1 | 0.131 | |
| OLR1 | oxidized low density lipoprotein (lectin-like) receptor 1 | 0.127 | |
| PLEK | pleckstrin | 0.125 | |
| GZMK | granzyme K (granzyme 3; tryptase II) | 0.119 | |
| CXCR3 | chemokine (C-X-C motif) receptor 3 | 0.115 | |
| KLRB1 | killer cell lectin-like receptor subfamily B, member 1 | 0.111 | |
| XCL1 | chemokine (C motif) ligand 1 | 0.110 | |
| MMP9 | matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase) | 0.110 | |
| IL1A | interleukin 1, alpha | 0.104 | |
| SLAMF8 | SLAM family member 8 | 0.098 | |
| TNFAIP6 | tumor necrosis factor, alpha-induced protein 6 | 0.098 | |
| CD48 | CD48 molecule | 0.095 | |
| CD84 | CD84 molecule | 0.085 | |
| PLA2G7 | phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma) | 0.085 | |
| CCR3 | chemokine (C-C motif) receptor 3 | 0.085 | |
| CD2 | CD2 molecule | 0.078 | |
| CD40 | CD40 molecule, TNF receptor superfamily member 5 | 0.075 | |
| EBI3 | Epstein-Barr virus induced 3 | 0.074 | |
| CCL3L3 | chemokine (C-C motif) ligand 3-like 3 | 0.072 | |
| IL21R | interleukin 21 receptor | 0.070 | |
| CCL17 | chemokine (C-C motif) ligand 17 | 0.070 | |
| MSC | musculin | 0.069 | |
| CCL1 | chemokine (C-C motif) ligand 1 | 0.063 | |
| INHBA | inhibin, beta A | 0.063 | |
| CHMP2B | chromatin modifying protein 2B | 0.061 | |
| IL18R1 | interleukin 18 receptor 1 | 0.060 | |
| IRF8 | interferon regulatory factor 8 | 0.060 | |
| RELB | v-rel reticuloendotheliosis viral oncogene homolog B | 0.059 |
Loading network...
Mus musculus
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| Ccr2 | chemokine (C-C motif) receptor 2 | 0.999 | |
| Ccl2 | chemokine (C-C motif) ligand 2 | 0.998 | |
| Cd44 | CD44 antigen | 0.973 | |
| Ifng | interferon gamma | 0.935 | |
| Selp | selectin, platelet | 0.853 | |
| Tlr4 | toll-like receptor 4 | 0.817 | |
| Prdm1 | PR domain containing 1, with ZNF domain | 0.813 | |
| Ccl3 | chemokine (C-C motif) ligand 3 | 0.774 | |
| Ccl4 | chemokine (C-C motif) ligand 4 | 0.750 | |
| Klrk1 | killer cell lectin-like receptor subfamily K, member 1 | 0.728 | |
| Tlr2 | toll-like receptor 2 | 0.699 | |
| Mmp9 | matrix metallopeptidase 9 | 0.634 | |
| Xcr1 | chemokine (C motif) receptor 1 | 0.620 | |
| Tnf | tumor necrosis factor | 0.583 | |
| Klrd1 | killer cell lectin-like receptor, subfamily D, member 1 | 0.575 | |
| Ccr1 | chemokine (C-C motif) receptor 1 | 0.533 | |
| Ccr5 | chemokine (C-C motif) receptor 5 | 0.453 | |
| Fcrla | Fc receptor-like A | 0.451 | |
| Cxcr2 | chemokine (C-X-C motif) receptor 2 | 0.418 | |
| Ccr6 | chemokine (C-C motif) receptor 6 | 0.414 | |
| Cd7 | CD7 antigen | 0.401 | |
| Map3k14 | mitogen-activated protein kinase kinase kinase 14 | 0.377 | |
| Tnfsf14 | tumor necrosis factor (ligand) superfamily, member 14 | 0.370 | |
| Gzmb | granzyme B | 0.356 | |
| H2-Ob | histocompatibility 2, O region beta locus | 0.345 | |
| Il10 | interleukin 10 | 0.333 | |
| Ncr1 | natural cytotoxicity triggering receptor 1 | 0.313 | |
| Cd180 | CD180 antigen | 0.312 | |
| Klrg1 | killer cell lectin-like receptor subfamily G, member 1 | 0.303 | |
| Blk | B lymphoid kinase | 0.287 | |
| Fasl | Fas ligand (TNF superfamily, member 6) | 0.282 | |
| Itgax | integrin alpha X | 0.269 | |
| Il18rap | interleukin 18 receptor accessory protein | 0.268 | |
| Klrc1 | killer cell lectin-like receptor subfamily C, member 1 | 0.237 | |
| Cd40 | CD40 antigen | 0.233 | |
| Ifngr1 | interferon gamma receptor 1 | 0.226 | |
| Cxcl13 | chemokine (C-X-C motif) ligand 13 | 0.222 | |
| Itk | IL2-inducible T-cell kinase | 0.217 | |
| Icos | inducible T-cell co-stimulator | 0.216 | |
| Lepr | leptin receptor | 0.201 | |
| Il12rb2 | interleukin 12 receptor, beta 2 | 0.200 | |
| Klra5 | killer cell lectin-like receptor, subfamily A, member 5 | 0.196 | |
| Lta | lymphotoxin A | 0.188 | |
| Gzmk | granzyme K | 0.184 | |
| Klra9 | killer cell lectin-like receptor subfamily A, member 9 | 0.182 | |
| Gzma | granzyme A | 0.181 | |
| Klrb1b | killer cell lectin-like receptor subfamily B member 1B | 0.180 | |
| Il18r1 | interleukin 18 receptor 1 | 0.177 | |
| Runx1 | runt related transcription factor 1 | 0.173 | |
| Cd96 | CD96 antigen | 0.171 | |
| P2rx7 | purinergic receptor P2X, ligand-gated ion channel, 7 | 0.170 | |
| Spp1 | secreted phosphoprotein 1 | 0.168 | |
| Gcet2 | germinal center expressed transcript 2 | 0.159 | |
| Ctsw | cathepsin W | 0.158 | |
| Fcer2a | Fc receptor, IgE, low affinity II, alpha polypeptide | 0.149 | |
| Ccr3 | chemokine (C-C motif) receptor 3 | 0.145 | |
| Spib | Spi-B transcription factor (Spi-1/PU.1 related) | 0.141 | |
| Ikzf1 | IKAROS family zinc finger 1 | 0.135 | |
| Il2rb | interleukin 2 receptor, beta chain | 0.134 | |
| Cx3cr1 | chemokine (C-X3-C) receptor 1 | 0.125 | |
| Il1r1 | interleukin 1 receptor, type I | 0.124 | |
| Slfn4 | schlafen 4 | 0.118 | |
| Ctla4 | cytotoxic T-lymphocyte-associated protein 4 | 0.116 | |
| Gpr33 | G protein-coupled receptor 33 | 0.116 | |
| Ms4a1 | membrane-spanning 4-domains, subfamily A, member 1 | 0.115 | |
| Cxcr3 | chemokine (C-X-C motif) receptor 3 | 0.113 | |
| Sh2d2a | SH2 domain protein 2A | 0.111 | |
| Nos2 | nitric oxide synthase 2, inducible | 0.107 | |
| Cd6 | CD6 antigen | 0.105 | |
| Cd2 | CD2 antigen | 0.103 | |
| Xcl1 | chemokine (C motif) ligand 1 | 0.097 | |
| Il1b | interleukin 1 beta | 0.096 | |
| Art2a-ps | ADP-ribosyltransferase 2a, pseudogene | 0.089 | |
| Slamf1 | signaling lymphocytic activation molecule family member 1 | 0.087 | |
| Ltb | lymphotoxin B | 0.087 | |
| Spn | sialophorin | 0.086 | |
| Tnfrsf1a | tumor necrosis factor receptor superfamily, member 1a | 0.085 | |
| Itgal | integrin alpha L | 0.085 | |
| S1pr4 | sphingosine-1-phosphate receptor 4 | 0.084 | |
| Elk4 | ELK4, member of ETS oncogene family | 0.083 | |
| Csf1 | colony stimulating factor 1 (macrophage) | 0.082 | |
| Tnfsf8 | tumor necrosis factor (ligand) superfamily, member 8 | 0.082 | |
| Fgd3 | FYVE, RhoGEF and PH domain containing 3 | 0.081 | |
| Slamf6 | SLAM family member 6 | 0.078 | |
| Icam1 | intercellular adhesion molecule 1 | 0.078 | |
| C3ar1 | complement component 3a receptor 1 | 0.077 | |
| Pik3cg | phosphoinositide-3-kinase, catalytic, gamma polypeptide | 0.072 | |
| Il27ra | interleukin 27 receptor, alpha | 0.071 | |
| F2rl2 | coagulation factor II (thrombin) receptor-like 2 | 0.069 | |
| Igk | immunoglobulin kappa chain complex | 0.066 | |
| Sell | selectin, lymphocyte | 0.065 | |
| Igj | immunoglobulin joining chain | 0.065 | |
| Pou2af1 | POU domain, class 2, associating factor 1 | 0.064 | |
| Id2 | inhibitor of DNA binding 2 | 0.063 | |
| Tlr7 | toll-like receptor 7 | 0.063 | |
| Ccr7 | chemokine (C-C motif) receptor 7 | 0.060 | |
| Tnfsf11 | tumor necrosis factor (ligand) superfamily, member 11 | 0.059 | |
| Bex6 | brain expressed gene 6 | 0.059 | |
| Tnfrsf4 | tumor necrosis factor receptor superfamily, member 4 | 0.058 | |
| Gimap7 | GTPase, IMAP family member 7 | 0.056 |
Loading network...
Rattus norvegicus
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| Ccl4 | chemokine (C-C motif) ligand 4 | 0.012 |