Process View
The network for 'regulation of testosterone biosynthetic process' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.
Any process that modulates the frequency, rate or extent of testosterone biosynthetic process.
Name | Description | Probability | Func Analog Organism |
---|---|---|---|
AKR1C1 | aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase) | 1.000 | |
AKR1C2 | aldo-keto reductase family 1, member C2 (dihydrodiol dehydrogenase 2; bile acid binding protein; 3-alpha hydroxysteroid dehydrogenase, type III) | 1.000 | |
AKR1C3 | aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II) | 1.000 | |
ZHX1 | zinc fingers and homeoboxes 1 | 0.996 | |
FGF18 | fibroblast growth factor 18 | 0.981 | |
WNT1 | wingless-type MMTV integration site family, member 1 | 0.563 | |
FGF3 | fibroblast growth factor 3 | 0.389 | |
SFRP1 | secreted frizzled-related protein 1 | 0.382 | |
WIF1 | WNT inhibitory factor 1 | 0.369 | |
WNT10A | wingless-type MMTV integration site family, member 10A | 0.322 | |
IHH | Indian hedgehog | 0.296 | |
WNT3 | wingless-type MMTV integration site family, member 3 | 0.268 | |
NQO1 | NAD(P)H dehydrogenase, quinone 1 | 0.268 | |
CYP26A1 | cytochrome P450, family 26, subfamily A, polypeptide 1 | 0.258 | |
PIR | pirin (iron-binding nuclear protein) | 0.211 | |
AQP5 | aquaporin 5 | 0.189 | |
MMP11 | matrix metallopeptidase 11 (stromelysin 3) | 0.186 | |
PAX8 | paired box 8 | 0.171 | |
AKR1B10 | aldo-keto reductase family 1, member B10 (aldose reductase) | 0.145 | |
FGF8 | fibroblast growth factor 8 (androgen-induced) | 0.129 | |
HOXC8 | homeobox C8 | 0.128 | |
FOXC2 | forkhead box C2 (MFH-1, mesenchyme forkhead 1) | 0.123 | |
SHH | sonic hedgehog | 0.118 | |
TLX3 | T-cell leukemia homeobox 3 | 0.101 | |
HES2 | hairy and enhancer of split 2 (Drosophila) | 0.094 | |
HMX1 | H6 family homeobox 1 | 0.087 | |
SLC18A3 | solute carrier family 18 (vesicular acetylcholine), member 3 | 0.084 | |
AADAC | arylacetamide deacetylase (esterase) | 0.081 | |
FGF4 | fibroblast growth factor 4 | 0.072 | |
GPX2 | glutathione peroxidase 2 (gastrointestinal) | 0.071 | |
FOXD3 | forkhead box D3 | 0.071 | |
CRLF1 | cytokine receptor-like factor 1 | 0.068 | |
HS3ST6 | heparan sulfate (glucosamine) 3-O-sulfotransferase 6 | 0.066 | |
ACAN | aggrecan | 0.059 | |
ACACA | acetyl-CoA carboxylase alpha | 0.057 | |
ENTPD2 | ectonucleoside triphosphate diphosphohydrolase 2 | 0.057 | |
AKR1C4 | aldo-keto reductase family 1, member C4 (chlordecone reductase; 3-alpha hydroxysteroid dehydrogenase, type I; dihydrodiol dehydrogenase 4) | 0.055 | |
BMP8A | bone morphogenetic protein 8a | 0.055 | |
ST8SIA2 | ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2 | 0.053 | |
NPAS1 | neuronal PAS domain protein 1 | 0.049 | |
ZNF33B | zinc finger protein 33B | 0.049 | |
SOX1 | SRY (sex determining region Y)-box 1 | 0.048 | |
PEX14 | peroxisomal biogenesis factor 14 | 0.048 | |
SOX21 | SRY (sex determining region Y)-box 21 | 0.047 | |
FOXE1 | forkhead box E1 (thyroid transcription factor 2) | 0.046 | |
HOXD13 | homeobox D13 | 0.046 | |
CDX1 | caudal type homeobox 1 | 0.046 | |
GUCA2A | guanylate cyclase activator 2A (guanylin) | 0.046 | |
HYAL1 | hyaluronoglucosaminidase 1 | 0.045 | |
NKD2 | naked cuticle homolog 2 (Drosophila) | 0.045 | |
FIBCD1 | fibrinogen C domain containing 1 | 0.045 | |
HES5 | hairy and enhancer of split 5 (Drosophila) | 0.044 | |
SLC6A2 | solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2 | 0.042 | |
DLX4 | distal-less homeobox 4 | 0.042 | |
FOXL1 | forkhead box L1 | 0.041 | |
FOXF2 | forkhead box F2 | 0.039 | |
PKP1 | plakophilin 1 (ectodermal dysplasia/skin fragility syndrome) | 0.039 | |
LMX1A | LIM homeobox transcription factor 1, alpha | 0.039 | |
KCNJ5 | potassium inwardly-rectifying channel, subfamily J, member 5 | 0.038 | |
RARG | retinoic acid receptor, gamma | 0.037 | |
CYP4F12 | cytochrome P450, family 4, subfamily F, polypeptide 12 | 0.036 | |
SIX2 | SIX homeobox 2 | 0.036 | |
BHLHE23 | basic helix-loop-helix family, member e23 | 0.036 | |
P2RX2 | purinergic receptor P2X, ligand-gated ion channel, 2 | 0.035 | |
FGF19 | fibroblast growth factor 19 | 0.035 | |
HOXD10 | homeobox D10 | 0.034 | |
GDNF | glial cell derived neurotrophic factor | 0.034 | |
BMP4 | bone morphogenetic protein 4 | 0.033 | |
PIGC | phosphatidylinositol glycan anchor biosynthesis, class C | 0.030 | |
CYP7B1 | cytochrome P450, family 7, subfamily B, polypeptide 1 | 0.030 | |
WNT10B | wingless-type MMTV integration site family, member 10B | 0.030 | |
EXOC3L2 | exocyst complex component 3-like 2 | 0.030 | |
CXCL14 | chemokine (C-X-C motif) ligand 14 | 0.029 | |
APOF | apolipoprotein F | 0.029 | |
CSF2 | colony stimulating factor 2 (granulocyte-macrophage) | 0.029 | |
ABCC2 | ATP-binding cassette, sub-family C (CFTR/MRP), member 2 | 0.029 | |
CADM3 | cell adhesion molecule 3 | 0.029 | |
NKD1 | naked cuticle homolog 1 (Drosophila) | 0.029 | |
HOXA11 | homeobox A11 | 0.028 | |
PITX1 | paired-like homeodomain 1 | 0.028 | |
FOXB1 | forkhead box B1 | 0.028 | |
NEUROG2 | neurogenin 2 | 0.028 | |
ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | 0.027 | |
DSG1 | desmoglein 1 | 0.027 | |
ANXA10 | annexin A10 | 0.027 | |
RAX | retina and anterior neural fold homeobox | 0.027 | |
KCNK9 | potassium channel, subfamily K, member 9 | 0.026 | |
POU3F1 | POU class 3 homeobox 1 | 0.026 | |
GBX2 | gastrulation brain homeobox 2 | 0.026 | |
LBP | lipopolysaccharide binding protein | 0.026 | |
DAPK2 | death-associated protein kinase 2 | 0.026 | |
MAGEA11 | melanoma antigen family A, 11 | 0.025 | |
EVPL | envoplakin | 0.025 | |
HOXB1 | homeobox B1 | 0.025 | |
COL4A6 | collagen, type IV, alpha 6 | 0.025 | |
TH | tyrosine hydroxylase | 0.025 | |
CHRD | chordin | 0.025 | |
HSD17B2 | hydroxysteroid (17-beta) dehydrogenase 2 | 0.025 | |
ADAMTS2 | ADAM metallopeptidase with thrombospondin type 1 motif, 2 | 0.024 | |
ROR2 | receptor tyrosine kinase-like orphan receptor 2 | 0.024 |
Name | Description | Probability | Func Analog Organism |
---|---|---|---|
Wnt3a | wingless-related MMTV integration site 3A | 0.994 | |
Pax2 | paired box gene 2 | 0.989 | |
Wnt4 | wingless-related MMTV integration site 4 | 0.968 | |
T | brachyury | 0.942 | |
Dkk1 | dickkopf homolog 1 (Xenopus laevis) | 0.939 | |
Pax8 | paired box gene 8 | 0.834 | |
Gdnf | glial cell line derived neurotrophic factor | 0.799 | |
Lhx1 | LIM homeobox protein 1 | 0.763 | |
Kl | klotho | 0.707 | |
Ror2 | receptor tyrosine kinase-like orphan receptor 2 | 0.545 | |
Wnt10b | wingless related MMTV integration site 10b | 0.540 | |
Fgf8 | fibroblast growth factor 8 | 0.528 | |
Hoxa2 | homeobox A2 | 0.466 | |
Dact1 | dapper homolog 1, antagonist of beta-catenin (xenopus) | 0.443 | |
Fgf18 | fibroblast growth factor 18 | 0.430 | |
Col13a1 | collagen, type XIII, alpha 1 | 0.410 | |
Amhr2 | anti-Mullerian hormone type 2 receptor | 0.382 | |
Pcsk5 | proprotein convertase subtilisin/kexin type 5 | 0.377 | |
Bmp7 | bone morphogenetic protein 7 | 0.370 | |
Cyp26a1 | cytochrome P450, family 26, subfamily a, polypeptide 1 | 0.325 | |
Wnt9a | wingless-type MMTV integration site 9A | 0.318 | |
Fzd10 | frizzled homolog 10 (Drosophila) | 0.292 | |
Fzd8 | frizzled homolog 8 (Drosophila) | 0.283 | |
Porcn | porcupine homolog (Drosophila) | 0.277 | |
Ihh | Indian hedgehog | 0.252 | |
Wnt2b | wingless related MMTV integration site 2b | 0.245 | |
Krt15 | keratin 15 | 0.238 | |
Tbx2 | T-box 2 | 0.201 | |
Emid2 | EMI domain containing 2 | 0.199 | |
Hsd11b2 | hydroxysteroid 11-beta dehydrogenase 2 | 0.196 | |
Clic3 | chloride intracellular channel 3 | 0.195 | |
Twist2 | twist homolog 2 (Drosophila) | 0.179 | |
Wnt7a | wingless-related MMTV integration site 7A | 0.169 | |
Slc34a2 | solute carrier family 34 (sodium phosphate), member 2 | 0.169 | |
Vax1 | ventral anterior homeobox containing gene 1 | 0.165 | |
Gli1 | GLI-Kruppel family member GLI1 | 0.164 | |
Trp73 | transformation related protein 73 | 0.156 | |
Hoxd11 | homeobox D11 | 0.153 | |
Efna4 | ephrin A4 | 0.147 | |
Cdx1 | caudal type homeobox 1 | 0.140 | |
Sim2 | single-minded homolog 2 (Drosophila) | 0.132 | |
Wnt6 | wingless-related MMTV integration site 6 | 0.132 | |
Cldn3 | claudin 3 | 0.132 | |
Sox7 | SRY-box containing gene 7 | 0.127 | |
Barx1 | BarH-like homeobox 1 | 0.127 | |
Zfp503 | zinc finger protein 503 | 0.125 | |
Amh | anti-Mullerian hormone | 0.125 | |
Pou3f3 | POU domain, class 3, transcription factor 3 | 0.123 | |
Lrp6 | low density lipoprotein receptor-related protein 6 | 0.122 | |
Igdcc3 | immunoglobulin superfamily, DCC subclass, member 3 | 0.121 | |
Btbd17 | BTB (POZ) domain containing 17 | 0.121 | |
Sema3b | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B | 0.117 | |
Rbpjl | recombination signal binding protein for immunoglobulin kappa J region-like | 0.114 | |
Vstm2b | V-set and transmembrane domain containing 2B | 0.113 | |
Hoxc9 | homeobox C9 | 0.105 | |
Igfals | insulin-like growth factor binding protein, acid labile subunit | 0.104 | |
Fgfr4 | fibroblast growth factor receptor 4 | 0.102 | |
Pou3f1 | POU domain, class 3, transcription factor 1 | 0.101 | |
Rspo1 | R-spondin homolog (Xenopus laevis) | 0.100 | |
Prm3 | protamine 3 | 0.099 | |
Tctex1d4 | Tctex1 domain containing 4 | 0.099 | |
Foxf1a | forkhead box F1a | 0.098 | |
Muc5ac | mucin 5, subtypes A and C, tracheobronchial/gastric | 0.098 | |
Hmx3 | H6 homeobox 3 | 0.095 | |
Lmx1a | LIM homeobox transcription factor 1 alpha | 0.094 | |
Lyzl4 | lysozyme-like 4 | 0.094 | |
Adra2b | adrenergic receptor, alpha 2b | 0.093 | |
Angpt4 | angiopoietin 4 | 0.091 | |
Tmeff2 | transmembrane protein with EGF-like and two follistatin-like domains 2 | 0.089 | |
Hoxa4 | homeobox A4 | 0.089 | |
Nkx2-4 | NK2 transcription factor related, locus 4 (Drosophila) | 0.088 | |
Oxtr | oxytocin receptor | 0.088 | |
Adamtsl5 | ADAMTS-like 5 | 0.086 | |
Fgf3 | fibroblast growth factor 3 | 0.086 | |
Epha1 | Eph receptor A1 | 0.085 | |
Pvrl1 | poliovirus receptor-related 1 | 0.085 | |
Mixl1 | Mix1 homeobox-like 1 (Xenopus laevis) | 0.083 | |
Acan | aggrecan | 0.083 | |
Chrdl2 | chordin-like 2 | 0.082 | |
Pax1 | paired box gene 1 | 0.082 | |
Wnt1 | wingless-related MMTV integration site 1 | 0.081 | |
Rarb | retinoic acid receptor, beta | 0.080 | |
Dmgdh | dimethylglycine dehydrogenase precursor | 0.080 | |
Ntn3 | netrin 3 | 0.078 | |
Wnt2 | wingless-related MMTV integration site 2 | 0.078 | |
Npas1 | neuronal PAS domain protein 1 | 0.077 | |
Foxf2 | forkhead box F2 | 0.075 | |
Rarg | retinoic acid receptor, gamma | 0.074 | |
Nkx1-2 | NK1 transcription factor related, locus 2 (Drosophila) | 0.074 | |
Slurp1 | secreted Ly6/Plaur domain containing 1 | 0.074 | |
Bnc1 | basonuclin 1 | 0.072 | |
Scube1 | signal peptide, CUB domain, EGF-like 1 | 0.072 | |
Otx1 | orthodenticle homolog 1 (Drosophila) | 0.071 | |
Hoxd9 | homeobox D9 | 0.071 | |
Crlf1 | cytokine receptor-like factor 1 | 0.071 | |
Ret | ret proto-oncogene | 0.070 | |
Stra6 | stimulated by retinoic acid gene 6 | 0.070 | |
Bik | BCL2-interacting killer | 0.069 | |
Msln | mesothelin | 0.068 | |
Ephb2 | Eph receptor B2 | 0.068 |