The network for 'regulation of testosterone biosynthetic process' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

regulation of testosterone biosynthetic process

Any process that modulates the frequency, rate or extent of testosterone biosynthetic process.

Name Description Probability Func Analog Organism
AKR1C1 aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase) 1.000
AKR1C2 aldo-keto reductase family 1, member C2 (dihydrodiol dehydrogenase 2; bile acid binding protein; 3-alpha hydroxysteroid dehydrogenase, type III) 1.000
AKR1C3 aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II) 1.000
ZHX1 zinc fingers and homeoboxes 1 0.996
FGF18 fibroblast growth factor 18 0.981
WNT1 wingless-type MMTV integration site family, member 1 0.563
FGF3 fibroblast growth factor 3 0.389
SFRP1 secreted frizzled-related protein 1 0.382
WIF1 WNT inhibitory factor 1 0.369
WNT10A wingless-type MMTV integration site family, member 10A 0.322
IHH Indian hedgehog 0.296
WNT3 wingless-type MMTV integration site family, member 3 0.268
NQO1 NAD(P)H dehydrogenase, quinone 1 0.268
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1 0.258
PIR pirin (iron-binding nuclear protein) 0.211
AQP5 aquaporin 5 0.189
MMP11 matrix metallopeptidase 11 (stromelysin 3) 0.186
PAX8 paired box 8 0.171
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase) 0.145
FGF8 fibroblast growth factor 8 (androgen-induced) 0.129
HOXC8 homeobox C8 0.128
FOXC2 forkhead box C2 (MFH-1, mesenchyme forkhead 1) 0.123
SHH sonic hedgehog 0.118
TLX3 T-cell leukemia homeobox 3 0.101
HES2 hairy and enhancer of split 2 (Drosophila) 0.094
HMX1 H6 family homeobox 1 0.087
SLC18A3 solute carrier family 18 (vesicular acetylcholine), member 3 0.084
AADAC arylacetamide deacetylase (esterase) 0.081
FGF4 fibroblast growth factor 4 0.072
GPX2 glutathione peroxidase 2 (gastrointestinal) 0.071
FOXD3 forkhead box D3 0.071
CRLF1 cytokine receptor-like factor 1 0.068
HS3ST6 heparan sulfate (glucosamine) 3-O-sulfotransferase 6 0.066
ACAN aggrecan 0.059
ACACA acetyl-CoA carboxylase alpha 0.057
ENTPD2 ectonucleoside triphosphate diphosphohydrolase 2 0.057
AKR1C4 aldo-keto reductase family 1, member C4 (chlordecone reductase; 3-alpha hydroxysteroid dehydrogenase, type I; dihydrodiol dehydrogenase 4) 0.055
BMP8A bone morphogenetic protein 8a 0.055
ST8SIA2 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2 0.053
NPAS1 neuronal PAS domain protein 1 0.049
ZNF33B zinc finger protein 33B 0.049
SOX1 SRY (sex determining region Y)-box 1 0.048
PEX14 peroxisomal biogenesis factor 14 0.048
SOX21 SRY (sex determining region Y)-box 21 0.047
FOXE1 forkhead box E1 (thyroid transcription factor 2) 0.046
HOXD13 homeobox D13 0.046
CDX1 caudal type homeobox 1 0.046
GUCA2A guanylate cyclase activator 2A (guanylin) 0.046
HYAL1 hyaluronoglucosaminidase 1 0.045
NKD2 naked cuticle homolog 2 (Drosophila) 0.045
FIBCD1 fibrinogen C domain containing 1 0.045
HES5 hairy and enhancer of split 5 (Drosophila) 0.044
SLC6A2 solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2 0.042
DLX4 distal-less homeobox 4 0.042
FOXL1 forkhead box L1 0.041
FOXF2 forkhead box F2 0.039
PKP1 plakophilin 1 (ectodermal dysplasia/skin fragility syndrome) 0.039
LMX1A LIM homeobox transcription factor 1, alpha 0.039
KCNJ5 potassium inwardly-rectifying channel, subfamily J, member 5 0.038
RARG retinoic acid receptor, gamma 0.037
CYP4F12 cytochrome P450, family 4, subfamily F, polypeptide 12 0.036
SIX2 SIX homeobox 2 0.036
BHLHE23 basic helix-loop-helix family, member e23 0.036
P2RX2 purinergic receptor P2X, ligand-gated ion channel, 2 0.035
FGF19 fibroblast growth factor 19 0.035
HOXD10 homeobox D10 0.034
GDNF glial cell derived neurotrophic factor 0.034
BMP4 bone morphogenetic protein 4 0.033
PIGC phosphatidylinositol glycan anchor biosynthesis, class C 0.030
CYP7B1 cytochrome P450, family 7, subfamily B, polypeptide 1 0.030
WNT10B wingless-type MMTV integration site family, member 10B 0.030
EXOC3L2 exocyst complex component 3-like 2 0.030
CXCL14 chemokine (C-X-C motif) ligand 14 0.029
APOF apolipoprotein F 0.029
CSF2 colony stimulating factor 2 (granulocyte-macrophage) 0.029
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2 0.029
CADM3 cell adhesion molecule 3 0.029
NKD1 naked cuticle homolog 1 (Drosophila) 0.029
HOXA11 homeobox A11 0.028
PITX1 paired-like homeodomain 1 0.028
FOXB1 forkhead box B1 0.028
NEUROG2 neurogenin 2 0.028
ALDH1A1 aldehyde dehydrogenase 1 family, member A1 0.027
DSG1 desmoglein 1 0.027
ANXA10 annexin A10 0.027
RAX retina and anterior neural fold homeobox 0.027
KCNK9 potassium channel, subfamily K, member 9 0.026
POU3F1 POU class 3 homeobox 1 0.026
GBX2 gastrulation brain homeobox 2 0.026
LBP lipopolysaccharide binding protein 0.026
DAPK2 death-associated protein kinase 2 0.026
MAGEA11 melanoma antigen family A, 11 0.025
EVPL envoplakin 0.025
HOXB1 homeobox B1 0.025
COL4A6 collagen, type IV, alpha 6 0.025
TH tyrosine hydroxylase 0.025
CHRD chordin 0.025
HSD17B2 hydroxysteroid (17-beta) dehydrogenase 2 0.025
ADAMTS2 ADAM metallopeptidase with thrombospondin type 1 motif, 2 0.024
ROR2 receptor tyrosine kinase-like orphan receptor 2 0.024
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
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Danio rerio
Name Description Probability Func Analog Organism
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Drosophila melanogaster
Name Description Probability Func Analog Organism
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Mus musculus
Name Description Probability Func Analog Organism
Wnt3a wingless-related MMTV integration site 3A 0.994
Pax2 paired box gene 2 0.989
Wnt4 wingless-related MMTV integration site 4 0.968
T brachyury 0.942
Dkk1 dickkopf homolog 1 (Xenopus laevis) 0.939
Pax8 paired box gene 8 0.834
Gdnf glial cell line derived neurotrophic factor 0.799
Lhx1 LIM homeobox protein 1 0.763
Kl klotho 0.707
Ror2 receptor tyrosine kinase-like orphan receptor 2 0.545
Wnt10b wingless related MMTV integration site 10b 0.540
Fgf8 fibroblast growth factor 8 0.528
Hoxa2 homeobox A2 0.466
Dact1 dapper homolog 1, antagonist of beta-catenin (xenopus) 0.443
Fgf18 fibroblast growth factor 18 0.430
Col13a1 collagen, type XIII, alpha 1 0.410
Amhr2 anti-Mullerian hormone type 2 receptor 0.382
Pcsk5 proprotein convertase subtilisin/kexin type 5 0.377
Bmp7 bone morphogenetic protein 7 0.370
Cyp26a1 cytochrome P450, family 26, subfamily a, polypeptide 1 0.325
Wnt9a wingless-type MMTV integration site 9A 0.318
Fzd10 frizzled homolog 10 (Drosophila) 0.292
Fzd8 frizzled homolog 8 (Drosophila) 0.283
Porcn porcupine homolog (Drosophila) 0.277
Ihh Indian hedgehog 0.252
Wnt2b wingless related MMTV integration site 2b 0.245
Krt15 keratin 15 0.238
Tbx2 T-box 2 0.201
Emid2 EMI domain containing 2 0.199
Hsd11b2 hydroxysteroid 11-beta dehydrogenase 2 0.196
Clic3 chloride intracellular channel 3 0.195
Twist2 twist homolog 2 (Drosophila) 0.179
Wnt7a wingless-related MMTV integration site 7A 0.169
Slc34a2 solute carrier family 34 (sodium phosphate), member 2 0.169
Vax1 ventral anterior homeobox containing gene 1 0.165
Gli1 GLI-Kruppel family member GLI1 0.164
Trp73 transformation related protein 73 0.156
Hoxd11 homeobox D11 0.153
Efna4 ephrin A4 0.147
Cdx1 caudal type homeobox 1 0.140
Sim2 single-minded homolog 2 (Drosophila) 0.132
Wnt6 wingless-related MMTV integration site 6 0.132
Cldn3 claudin 3 0.132
Sox7 SRY-box containing gene 7 0.127
Barx1 BarH-like homeobox 1 0.127
Zfp503 zinc finger protein 503 0.125
Amh anti-Mullerian hormone 0.125
Pou3f3 POU domain, class 3, transcription factor 3 0.123
Lrp6 low density lipoprotein receptor-related protein 6 0.122
Igdcc3 immunoglobulin superfamily, DCC subclass, member 3 0.121
Btbd17 BTB (POZ) domain containing 17 0.121
Sema3b sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B 0.117
Rbpjl recombination signal binding protein for immunoglobulin kappa J region-like 0.114
Vstm2b V-set and transmembrane domain containing 2B 0.113
Hoxc9 homeobox C9 0.105
Igfals insulin-like growth factor binding protein, acid labile subunit 0.104
Fgfr4 fibroblast growth factor receptor 4 0.102
Pou3f1 POU domain, class 3, transcription factor 1 0.101
Rspo1 R-spondin homolog (Xenopus laevis) 0.100
Prm3 protamine 3 0.099
Tctex1d4 Tctex1 domain containing 4 0.099
Foxf1a forkhead box F1a 0.098
Muc5ac mucin 5, subtypes A and C, tracheobronchial/gastric 0.098
Hmx3 H6 homeobox 3 0.095
Lmx1a LIM homeobox transcription factor 1 alpha 0.094
Lyzl4 lysozyme-like 4 0.094
Adra2b adrenergic receptor, alpha 2b 0.093
Angpt4 angiopoietin 4 0.091
Tmeff2 transmembrane protein with EGF-like and two follistatin-like domains 2 0.089
Hoxa4 homeobox A4 0.089
Nkx2-4 NK2 transcription factor related, locus 4 (Drosophila) 0.088
Oxtr oxytocin receptor 0.088
Adamtsl5 ADAMTS-like 5 0.086
Fgf3 fibroblast growth factor 3 0.086
Epha1 Eph receptor A1 0.085
Pvrl1 poliovirus receptor-related 1 0.085
Mixl1 Mix1 homeobox-like 1 (Xenopus laevis) 0.083
Acan aggrecan 0.083
Chrdl2 chordin-like 2 0.082
Pax1 paired box gene 1 0.082
Wnt1 wingless-related MMTV integration site 1 0.081
Rarb retinoic acid receptor, beta 0.080
Dmgdh dimethylglycine dehydrogenase precursor 0.080
Ntn3 netrin 3 0.078
Wnt2 wingless-related MMTV integration site 2 0.078
Npas1 neuronal PAS domain protein 1 0.077
Foxf2 forkhead box F2 0.075
Rarg retinoic acid receptor, gamma 0.074
Nkx1-2 NK1 transcription factor related, locus 2 (Drosophila) 0.074
Slurp1 secreted Ly6/Plaur domain containing 1 0.074
Bnc1 basonuclin 1 0.072
Scube1 signal peptide, CUB domain, EGF-like 1 0.072
Otx1 orthodenticle homolog 1 (Drosophila) 0.071
Hoxd9 homeobox D9 0.071
Crlf1 cytokine receptor-like factor 1 0.071
Ret ret proto-oncogene 0.070
Stra6 stimulated by retinoic acid gene 6 0.070
Bik BCL2-interacting killer 0.069
Msln mesothelin 0.068
Ephb2 Eph receptor B2 0.068
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Rattus norvegicus
Name Description Probability Func Analog Organism
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism