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Multiple Organisms

9 cis retinoic acid biosynthetic process

The chemical reactions and pathways resulting in the formation of 9-cis-retinoic acid, a metabolically active vitamin A derivative.

Mus musculus
Name Description Probability Func Analog Organism
Ece1 endothelin converting enzyme 1 0.353
Ednra endothelin receptor type A 0.218
Rarg retinoic acid receptor, gamma 0.213
Hoxa1 homeobox A1 0.180
Foxc2 forkhead box C2 0.179
Otc ornithine transcarbamylase 0.145
Pck1 phosphoenolpyruvate carboxykinase 1, cytosolic 0.136
Cyp2d26 cytochrome P450, family 2, subfamily d, polypeptide 26 0.133
Rarb retinoic acid receptor, beta 0.118
Isl1 ISL1 transcription factor, LIM/homeodomain 0.116
Aldh1a1 aldehyde dehydrogenase family 1, subfamily A1 0.109
Vegfa vascular endothelial growth factor A 0.101
F12 coagulation factor XII (Hageman factor) 0.089
Fgf8 fibroblast growth factor 8 0.086
Ulk4 unc-51-like kinase 4 (C. elegans) 0.085
Nr1i2 nuclear receptor subfamily 1, group I, member 2 0.075
Apoa1 apolipoprotein A-I 0.067
BC089597 cDNA sequence BC089597 0.060
Acox2 acyl-Coenzyme A oxidase 2, branched chain 0.056
Aadac arylacetamide deacetylase (esterase) 0.054
Sgk2 serum/glucocorticoid regulated kinase 2 0.050
Iyd iodotyrosine deiodinase 0.050
Ces1c carboxylesterase 1C 0.048
Ahsg alpha-2-HS-glycoprotein 0.046
Hoxa3 homeobox A3 0.043
Bmp4 bone morphogenetic protein 4 0.043
Aldob aldolase B, fructose-bisphosphate 0.042
Gsta3 glutathione S-transferase, alpha 3 0.039
Cdx2 caudal type homeobox 2 0.039
Ces2a carboxylesterase 2A 0.038
Foxc1 forkhead box C1 0.038
Hgd homogentisate 1, 2-dioxygenase 0.036
Glyat glycine-N-acyltransferase 0.035
Pitx2 paired-like homeodomain transcription factor 2 0.035
Ces2e carboxylesterase 2E 0.030
Rdh7 retinol dehydrogenase 7 0.030
Nrp1 neuropilin 1 0.030
Serpinc1 serine (or cysteine) peptidase inhibitor, clade C (antithrombin), member 1 0.029
Wnk4 WNK lysine deficient protein kinase 4 0.028
Ambp alpha 1 microglobulin/bikunin 0.028
Pax2 paired box gene 2 0.028
Fbln1 fibulin 1 0.027
Cyp3a25 cytochrome P450, family 3, subfamily a, polypeptide 25 0.025
Sult1b1 sulfotransferase family 1B, member 1 0.025
Tbx22 T-box 22 0.022
Prodh2 proline dehydrogenase (oxidase) 2 0.022
Plg plasminogen 0.022
F13b coagulation factor XIII, beta subunit 0.022
Cyp2d9 cytochrome P450, family 2, subfamily d, polypeptide 9 0.021
Smo smoothened homolog (Drosophila) 0.021
Fabp1 fatty acid binding protein 1, liver 0.021
Cyp2j5 cytochrome P450, family 2, subfamily j, polypeptide 5 0.021
Six1 sine oculis-related homeobox 1 homolog (Drosophila) 0.020
Hsd3b6 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 6 0.019
Proc protein C 0.018
Ttr transthyretin 0.017
Gsta2 glutathione S-transferase, alpha 2 (Yc2) 0.017
Mettl7b methyltransferase like 7B 0.017
Sox4 SRY-box containing gene 4 0.017
Clec2h C-type lectin domain family 2, member h 0.016
Pzp pregnancy zone protein 0.016
Fgb fibrinogen beta chain 0.016
Ugt2b34 UDP glucuronosyltransferase 2 family, polypeptide B34 0.015
Pah phenylalanine hydroxylase 0.015
Baat bile acid-Coenzyme A: amino acid N-acyltransferase 0.015
Rdh9 retinol dehydrogenase 9 0.015
Ces1d carboxylesterase 1D 0.015
Abcc6 ATP-binding cassette, sub-family C (CFTR/MRP), member 6 0.015
Slc27a2 solute carrier family 27 (fatty acid transporter), member 2 0.014
Kif27 kinesin family member 27 0.014
Gbx2 gastrulation brain homeobox 2 0.014
Sirt3 sirtuin 3 (silent mating type information regulation 2, homolog) 3 (S. cerevisiae) 0.014
Acot12 acyl-CoA thioesterase 12 0.013
Slc22a1 solute carrier family 22 (organic cation transporter), member 1 0.013
Defb1 defensin beta 1 0.013
Hnf4a hepatic nuclear factor 4, alpha 0.013
Abcc2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2 0.013
Pkhd1 polycystic kidney and hepatic disease 1 0.013
Slc2a2 solute carrier family 2 (facilitated glucose transporter), member 2 0.013
Wnt5a wingless-related MMTV integration site 5A 0.012
Rara retinoic acid receptor, alpha 0.012
Apoc3 apolipoprotein C-III 0.011
Acot4 acyl-CoA thioesterase 4 0.011
Upp2 uridine phosphorylase 2 0.011
Dpys dihydropyrimidinase 0.011
AI317395 expressed sequence AI317395 0.011
Hal histidine ammonia lyase 0.011
Rdh10 retinol dehydrogenase 10 (all-trans) 0.011
Sec14l2 SEC14-like 2 (S. cerevisiae) 0.011
Ces1g carboxylesterase 1G 0.011
Slc17a2 solute carrier family 17 (sodium phosphate), member 2 0.011
Slc26a1 solute carrier family 26 (sulfate transporter), member 1 0.011
Aldh1a7 aldehyde dehydrogenase family 1, subfamily A7 0.011
Mep1b meprin 1 beta 0.011
Chd7 chromodomain helicase DNA binding protein 7 0.010
G6pc glucose-6-phosphatase, catalytic 0.010
Cyp2c70 cytochrome P450, family 2, subfamily c, polypeptide 70 0.010
Aspdh aspartate dehydrogenase domain containing 0.010
Shh sonic hedgehog 0.010
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
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Danio rerio
Name Description Probability Func Analog Organism
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Drosophila melanogaster
Name Description Probability Func Analog Organism
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Homo sapiens
Name Description Probability Func Analog Organism
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial) 0.989
HMGCS2 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial) 0.135
HAAO 3-hydroxyanthranilate 3,4-dioxygenase 0.036
C8G complement component 8, gamma polypeptide 0.030
SLPI secretory leukocyte peptidase inhibitor 0.026
SAA4 serum amyloid A4, constitutive 0.025
NUPR1 nuclear protein, transcriptional regulator, 1 0.024
CYP4F2 cytochrome P450, family 4, subfamily F, polypeptide 2 0.024
CYP4F11 cytochrome P450, family 4, subfamily F, polypeptide 11 0.023
SLC22A1 solute carrier family 22 (organic cation transporter), member 1 0.023
HABP2 hyaluronan binding protein 2 0.023
SPP2 secreted phosphoprotein 2, 24kDa 0.022
SERPINC1 serpin peptidase inhibitor, clade C (antithrombin), member 1 0.020
LIPC lipase, hepatic 0.020
SLC7A9 solute carrier family 7 (cationic amino acid transporter, y+ system), member 9 0.019
HPX hemopexin 0.019
GJB1 gap junction protein, beta 1, 32kDa 0.018
SERPIND1 serpin peptidase inhibitor, clade D (heparin cofactor), member 1 0.018
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase) 0.018
PLG plasminogen 0.017
UGT1A3 UDP glucuronosyltransferase 1 family, polypeptide A3 0.017
ADH1C alcohol dehydrogenase 1C (class I), gamma polypeptide 0.016
SLC6A12 solute carrier family 6 (neurotransmitter transporter, betaine/GABA), member 12 0.015
KLK7 kallikrein-related peptidase 7 0.015
OTC ornithine carbamoyltransferase 0.015
IL22RA1 interleukin 22 receptor, alpha 1 0.015
DSG1 desmoglein 1 0.014
HNF4A hepatocyte nuclear factor 4, alpha 0.014
GCGR glucagon receptor 0.014
LGALS4 lectin, galactoside-binding, soluble, 4 0.014
PRSS8 protease, serine, 8 0.014
SERPINA6 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 6 0.013
ABP1 amiloride binding protein 1 (amine oxidase (copper-containing)) 0.013
ITIH4 inter-alpha (globulin) inhibitor H4 (plasma Kallikrein-sensitive glycoprotein) 0.013
ABCC6 ATP-binding cassette, sub-family C (CFTR/MRP), member 6 0.013
MAT1A methionine adenosyltransferase I, alpha 0.013
GPX2 glutathione peroxidase 2 (gastrointestinal) 0.013
AADAC arylacetamide deacetylase (esterase) 0.013
TM4SF5 transmembrane 4 L six family member 5 0.013
PRSS2 protease, serine, 2 (trypsin 2) 0.013
DBH dopamine beta-hydroxylase (dopamine beta-monooxygenase) 0.012
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2 0.012
SEC14L2 SEC14-like 2 (S. cerevisiae) 0.012
XDH xanthine dehydrogenase 0.012
MOSC1 MOCO sulphurase C-terminal domain containing 1 0.012
CYP2C18 cytochrome P450, family 2, subfamily C, polypeptide 18 0.012
CLCN2 chloride channel 2 0.012
CDHR5 cadherin-related family member 5 0.012
GNMT glycine N-methyltransferase 0.012
GCKR glucokinase (hexokinase 4) regulator 0.012
PRODH2 proline dehydrogenase (oxidase) 2 0.012
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 0.012
HDAC11 histone deacetylase 11 0.011
SULT1B1 sulfotransferase family, cytosolic, 1B, member 1 0.011
EPHX2 epoxide hydrolase 2, cytoplasmic 0.011
CRP C-reactive protein, pentraxin-related 0.011
TFR2 transferrin receptor 2 0.011
SULT2B1 sulfotransferase family, cytosolic, 2B, member 1 0.011
ANXA13 annexin A13 0.011
ABCB11 ATP-binding cassette, sub-family B (MDR/TAP), member 11 0.011
KNG1 kininogen 1 0.011
WFDC5 WAP four-disulfide core domain 5 0.011
NR1I2 nuclear receptor subfamily 1, group I, member 2 0.011
YBX2 Y box binding protein 2 0.011
ITIH2 inter-alpha (globulin) inhibitor H2 0.011
SPRR3 small proline-rich protein 3 0.011
SGK2 serum/glucocorticoid regulated kinase 2 0.010
SLC38A3 solute carrier family 38, member 3 0.010
SLC5A1 solute carrier family 5 (sodium/glucose cotransporter), member 1 0.010
ACPP acid phosphatase, prostate 0.010
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Rattus norvegicus
Name Description Probability Func Analog Organism
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism