IMP
Process View
The network for 'positive regulation of platelet derived growth factor receptor signaling pathway' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.
Multiple Organisms
positive regulation of platelet derived growth factor receptor signaling pathway
Any process that increases the frequency, rate or extent of the platelet-derived growth factor receptor signaling pathway.
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| Fgr | Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog | 0.248 | |
| Sirpa | signal-regulatory protein alpha | 0.207 | |
| Inpp5d | inositol polyphosphate-5-phosphatase D | 0.096 | |
| Bak1 | BCL2-antagonist/killer 1 | 0.077 | |
| Il1b | interleukin 1 beta | 0.075 | |
| Il2rg | interleukin 2 receptor, gamma | 0.054 | |
| Cd37 | CD37 molecule | 0.047 | |
| Lyn | v-yes-1 Yamaguchi sarcoma viral related oncogene homolog | 0.041 | |
| Mobkl2a | MOB1, Mps One Binder kinase activator-like 2A (yeast) | 0.037 | |
| Cd3d | CD3 molecule, delta | 0.036 | |
| Ptpn6 | protein tyrosine phosphatase, non-receptor type 6 | 0.035 | |
| Dock8 | dedicator of cytokinesis 8 | 0.033 | |
| Syk | spleen tyrosine kinase | 0.030 | |
| Pstpip1 | proline-serine-threonine phosphatase-interacting protein 1 | 0.028 | |
| Pik3ap1 | phosphoinositide-3-kinase adaptor protein 1 | 0.028 | |
| Klhl6 | kelch-like 6 (Drosophila) | 0.027 | |
| Cfp | complement factor properdin | 0.024 | |
| Csf3r | colony stimulating factor 3 receptor (granulocyte) | 0.023 | |
| Plcg2 | phospholipase C, gamma 2 | 0.023 | |
| Csk | c-src tyrosine kinase | 0.022 | |
| Prkcd | protein kinase C, delta | 0.021 | |
| Ncf4 | neutrophil cytosolic factor 4 | 0.020 | |
| LOC684996 | similar to chromosome 7 open reading frame 11 | 0.020 | |
| Myo1g | myosin IG | 0.020 | |
| Lcp2 | lymphocyte cytosolic protein 2 | 0.019 | |
| Bid | BH3 interacting domain death agonist | 0.019 | |
| Prkch | protein kinase C, eta | 0.019 | |
| Ppp1r9b | protein phosphatase 1, regulatory subunit 9B | 0.018 | |
| RGD1311493 | similar to CG13379-PA | 0.018 | |
| Accn1 | amiloride-sensitive cation channel 1, neuronal | 0.017 | |
| Neurl3 | neuralized homolog 3 (Drosophila) | 0.016 | |
| Cbl | Cas-Br-M (murine) ecotropic retroviral transforming sequence | 0.016 | |
| Ccl5 | chemokine (C-C motif) ligand 5 | 0.016 | |
| Smad1 | SMAD family member 1 | 0.015 | |
| Ripk3 | receptor-interacting serine-threonine kinase 3 | 0.015 | |
| Parp14 | poly (ADP-ribose) polymerase family, member 14 | 0.015 | |
| Cp | ceruloplasmin | 0.014 | |
| Batf | basic leucine zipper transcription factor, ATF-like | 0.014 | |
| Fmnl1 | formin-like 1 | 0.014 | |
| Hk1 | hexokinase 1 | 0.014 | |
| Cst7 | cystatin F (leukocystatin) | 0.013 | |
| Mef2a | myocyte enhancer factor 2a | 0.013 | |
| Arhgap25 | Rho GTPase activating protein 25 | 0.013 | |
| Lbp | lipopolysaccharide binding protein | 0.013 | |
| Ptpn18 | protein tyrosine phosphatase, non-receptor type 18 | 0.012 | |
| Arhgap27 | Rho GTPase activating protein 27 | 0.012 | |
| Ptprs | protein tyrosine phosphatase, receptor type, S | 0.012 | |
| Ptafr | platelet-activating factor receptor | 0.011 | |
| RT1-DOa | RT1 class II, locus DOa | 0.011 | |
| Cd180 | CD180 molecule | 0.010 | |
| Dok2 | docking protein 2 | 0.010 | |
| Il2rb | interleukin 2 receptor, beta | 0.010 | |
| Kmo | kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) | 0.010 |
Loading network...
Homo sapiens
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| FYN | FYN oncogene related to SRC, FGR, YES | 0.946 | |
| BCAR1 | breast cancer anti-estrogen resistance 1 | 0.861 | |
| GRB2 | growth factor receptor-bound protein 2 | 0.563 | |
| MUC1 | mucin 1, cell surface associated | 0.206 | |
| SRCIN1 | SRC kinase signaling inhibitor 1 | 0.169 | |
| CRK | v-crk sarcoma virus CT10 oncogene homolog (avian) | 0.103 | |
| PTK2 | PTK2 protein tyrosine kinase 2 | 0.099 | |
| ALB | albumin | 0.083 | |
| CTTN | cortactin | 0.064 | |
| YES1 | v-yes-1 Yamaguchi sarcoma viral oncogene homolog 1 | 0.054 | |
| PTK2B | PTK2B protein tyrosine kinase 2 beta | 0.054 | |
| ABL1 | c-abl oncogene 1, non-receptor tyrosine kinase | 0.044 | |
| SPRR2A | small proline-rich protein 2A | 0.042 | |
| PTPN1 | protein tyrosine phosphatase, non-receptor type 1 | 0.034 | |
| PTPN23 | protein tyrosine phosphatase, non-receptor type 23 | 0.033 | |
| EFS | embryonal Fyn-associated substrate | 0.028 | |
| FGA | fibrinogen alpha chain | 0.021 | |
| MET | met proto-oncogene (hepatocyte growth factor receptor) | 0.021 | |
| PTPN21 | protein tyrosine phosphatase, non-receptor type 21 | 0.017 | |
| PDCD6 | programmed cell death 6 | 0.017 | |
| SNX9 | sorting nexin 9 | 0.016 | |
| SH3KBP1 | SH3-domain kinase binding protein 1 | 0.015 | |
| PTPRA | protein tyrosine phosphatase, receptor type, A | 0.014 | |
| HCK | hemopoietic cell kinase | 0.013 | |
| CHMP4B | chromatin modifying protein 4B | 0.013 | |
| F7 | coagulation factor VII (serum prothrombin conversion accelerator) | 0.012 | |
| IGFALS | insulin-like growth factor binding protein, acid labile subunit | 0.012 | |
| PACSIN3 | protein kinase C and casein kinase substrate in neurons 3 | 0.011 | |
| SERPINC1 | serpin peptidase inhibitor, clade C (antithrombin), member 1 | 0.010 | |
| CRKL | v-crk sarcoma virus CT10 oncogene homolog (avian)-like | 0.010 | |
| HPD | 4-hydroxyphenylpyruvate dioxygenase | 0.010 |