The network for 'cellular catabolic process' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

cellular catabolic process

The chemical reactions and pathways resulting in the breakdown of substances, carried out by individual cells.

Name Description Probability Func Analog Organism
rpn-12 Protein RPN-12 0.833
egl-18 Protein EGL-18 0.815
rpt-2 Protein RPT-2 0.690
rpn-7 Protein RPN-7 0.684
rsp-8 Protein RSP-8 0.568
par-5 Protein PAR-5 0.547
rpt-5 Protein RPT-5 0.508
CELE_Y57G11C.3 Protein Y57G11C.3 0.508
rnr-1 Protein RNR-1 0.481
rpn-6.1 Protein RPN-6.1 0.458
rpt-3 Protein RPT-3 0.440
atp-2 Protein ATP-2 0.435
pbs-1 Protein PBS-1 0.426
zen-4 Protein ZEN-4 0.414
pcm-1 Protein PCM-1 0.405
rpn-5 Protein RPN-5 0.391
Y97E10AR.6 Protein Y97E10AR.6 0.388
rpn-10 Protein RPN-10 0.386
mei-1 Protein MEI-1 0.373
F56D2.6 Protein F56D2.6 0.368
pas-4 Protein PAS-4 0.336
acs-4 Protein ACS-4 0.331
sma-6 Protein SMA-6 0.331
pas-2 Protein PAS-2 0.316
csr-1 Protein CSR-1 0.313
cki-2 Protein CKI-2 0.310
csn-3 Protein CSN-3 0.307
CELE_C39E9.11 Protein C39E9.11 0.306
pbs-5 Protein PBS-5 0.297
unc-51 Protein UNC-51 0.296
Y47D3A.29 Protein Y47D3A.29 0.278
rod-1 Protein ROD-1 0.278
cyk-4 Protein CYK-4 0.275
dpy-31 Protein DPY-31 0.274
K10C9.3 Protein K10C9.3 0.273
pkc-3 Protein PKC-3 0.273
pkg-1 Protein PKG-1 0.272
app-1 Protein APP-1 0.270
pptr-2 Protein PPTR-2 0.266
chc-1 Protein CHC-1 0.265
rpn-11 Protein RPN-11 0.263
C56G2.7 Protein C56G2.7 0.261
rpn-9 Protein RPN-9 0.260
CELE_Y48B6A.1 Protein Y48B6A.1 0.257
cin-4 Protein CIN-4 0.253
atx-3 Protein ATX-3 0.252
ire-1 Protein IRE-1 0.251
cul-1 Protein CUL-1 0.245
npl-4.2 Protein NPL-4.2 0.244
D1081.8 Protein D1081.8 0.243
mvb-12 Protein MVB-12 0.243
tpxl-1 Protein TPXL-1 0.242
smc-3 Protein SMC-3 0.241
cdl-1 Protein CDL-1 0.238
F53F10.2 Protein F53F10.2 0.238
wdfy-2 Protein WDFY-2 0.238
nck-1 Protein NCK-1 0.237
rpa-1 Protein RPA-1 0.236
rpa-2 Protein RPA-2 0.235
F55G1.5 Protein F55G1.5 0.234
npp-19 Protein NPP-19 0.233
pri-2 Protein PRI-2 0.233
CELE_C10C6.6 Protein C10C6.6 0.232
vab-1 Protein VAB-1 0.231
stam-1 Protein STAM-1 0.228
tba-2 Protein TBA-2 0.224
tag-315 Protein TAG-315 0.224
gpb-1 Protein GPB-1 0.220
gck-2 Protein GCK-2 0.219
crt-1 Protein CRT-1 0.218
C33H5.17 Protein C33H5.17 0.218
ykt-6 Protein YKT-6 0.218
npp-1 Protein NPP-1 0.216
mbk-1 Protein MBK-1 0.215
npl-4.1 Protein NPL-4.1 0.215
lsl-1 Protein LSL-1 0.214
ncx-1 Protein NCX-1 0.213
goa-1 Protein GOA-1 0.212
ucr-2.3 Protein UCR-2.3 0.212
CELE_T10D4.6 Protein T10D4.6 0.211
miro-1 Protein MIRO-1 0.209
scc-3 Protein SCC-3 0.209
C41D11.3 Protein C41D11.3 0.207
letm-1 Protein LETM-1 0.207
sem-5 Protein SEM-5 0.207
mtm-9 Protein MTM-9 0.206
mpz-2 Protein MPZ-2 0.205
dlc-1 Protein DLC-1 0.204
lag-1 Protein LAG-1 0.203
tag-298 Protein TAG-298 0.203
hgrs-1 Protein HGRS-1 0.203
dnc-2 Protein DNC-2 0.202
ace-1 Protein ACE-1 0.202
rab-1 Protein RAB-1 0.202
mcm-7 Protein MCM-7 0.201
cct-6 Protein CCT-6 0.200
ceh-58 Protein CEH-58 0.199
pap-1 Protein PAP-1 0.196
rgl-1 Protein RGL-1 0.195
hmg-1.2 Protein HMG-1.2 0.194
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Danio rerio
Name Description Probability Func Analog Organism
ncor1 nuclear receptor co-repressor 1 0.402
pafah1b1b platelet-activating factor acetylhydrolase, isoform Ib, alpha subunit b 0.370
snai1a snail homolog 1a (Drosophila) 0.354
hspa5 heat shock protein 5 0.343
prdm1a PR domain containing 1a, with ZNF domain 0.329
psmb1 proteasome (prosome, macropain) subunit, beta type, 1 0.298
pitx3 paired-like homeodomain transcription factor 3 0.249
atp1b3b ATPase, Na+/K+ transporting, beta 3b polypeptide 0.231
gdf6a growth differentiation factor 6a 0.225
atp6v0ca ATPase, H+ transporting, lysosomal, V0 subunit c, a 0.208
bmp4 bone morphogenetic protein 4 0.195
ppp1r12a protein phosphatase 1, regulatory (inhibitor) subunit 12A 0.187
rab1a RAB1A, member RAS oncogene family 0.170
tp53 tumor protein p53 0.167
ccnb1 cyclin B1 0.136
psmc6 proteasome (prosome, macropain) 26S subunit, ATPase, 6 0.128
tnnt3b troponin T3b, skeletal, fast 0.121
sox9b SRY-box containing gene 9b 0.119
hadha hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenzyme A hydratase, alpha subunit 0.115
aldh7a1 aldehyde dehydrogenase 7 family, member A1 0.114
ddx42 DEAD (Asp-Glu-Ala-Asp) box polypeptide 42 0.113
sumo3a SMT3 suppressor of mif two 3 homolog 3a 0.106
psmb2 proteasome (prosome, macropain) subunit, beta type, 2 0.103
mecp2 methyl CpG binding protein 2 0.103
arf5 ADP-ribosylation factor 5 0.100
psen1 presenilin 1 0.099
plxnb2a plexin b2a 0.099
pax8 paired box gene 8 0.099
psmd4b proteasome (prosome, macropain) 26S subunit, non-ATPase, 4b 0.098
psmd6 proteasome (prosome, macropain) 26S subunit, non-ATPase, 6 0.097
pou5f1 POU domain, class 5, transcription factor 1 0.095
gcm2 glial cells missing homolog 2 (Drosophila) 0.095
tgfb3 transforming growth factor, beta 3 0.093
sec61al1 Sec61 alpha like 1 0.087
psma5 proteasome (prosome, macropain) subunit, alpha type,5 0.086
bnip3lb BCL2/adenovirus E1B interacting protein 3-like b 0.084
gnb1a guanine nucleotide binding protein (G protein), beta polypeptide 1a 0.077
zgc:174506 zgc:174506 0.077
fcho2 FCH domain only 2 0.076
ndufs4 NADH dehydrogenase (ubiquinone) Fe-S protein 4, (NADH-coenzyme Q reductase) 0.075
atp6v1h ATPase, H+ transporting, lysosomal, V1 subunit H 0.073
smad5 MAD homolog 5 (Drosophila) 0.072
arnt2 aryl hydrocarbon receptor nuclear translocator 2 0.071
ran ras-related nuclear protein 0.071
nhp2l1 NHP2 non-histone chromosome protein 2-like 1 (S. cerevisiae) 0.070
psmd1 proteasome (prosome, macropain) 26S subunit, non-ATPase, 1 0.068
jun jun proto-oncogene 0.068
tpm4 tropomyosin 4 0.067
sec61al2 Sec61 alpha like 2 0.067
psmb3 proteasome (prosome, macropain) subunit, beta type, 3 0.067
yes1 v-yes-1 Yamaguchi sarcoma viral oncogene homolog 1 0.067
smad2 MAD homolog 2 (Drosophila) 0.067
myog myogenin 0.067
ccnb2 cyclin B2 0.066
bcl2l10 BCL2-like 10 (apoptosis facilitator) 0.066
angptl3 angiopoietin-like 3 0.065
cmyb transcription factor cmyb 0.064
zgc:86903 zgc:86903 0.062
nploc4 nuclear protein localization 4 homolog (S. cerevisiae) 0.062
aldh18a1 aldehyde dehydrogenase 18 family, member A1 0.061
usp5 ubiquitin specific protease 5 0.061
mif macrophage migration inhibitory factor 0.059
ccna2 cyclin A2 0.059
cand1 cullin-associated and neddylation-dissociated 1 0.058
dnaja2 DnaJ (Hsp40) homolog, subfamily A, member 2 0.058
ppp1cb protein phosphatase 1, catalytic subunit, beta isoform 0.057
grina glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding) 0.056
furina furin (paired basic amino acid cleaving enzyme) a 0.056
zgc:73142 zgc:73142 0.056
spsb4a splA/ryanodine receptor domain and SOCS box containing 4a 0.055
gna12 guanine nucleotide binding protein (G protein) alpha 12 0.055
park7 parkinson disease (autosomal recessive, early onset) 7 0.055
zgc:55461 zgc:55461 0.055
bsdc1 BSD domain containing 1 0.054
ilf2 interleukin enhancer binding factor 2 0.054
tnni2a.4 troponin I, skeletal, fast 2a.4 0.054
sass6 spindle assembly 6 homolog (C. elegans) 0.054
mcl1b myeloid cell leukemia sequence 1b 0.053
acadl acyl-Coenzyme A dehydrogenase, long chain 0.053
dynlrb1 dynein, light chain, roadblock-type 1 0.053
got2a glutamic-oxaloacetic transaminase 2a, mitochondrial (aspartate aminotransferase 2) 0.052
adipor1b adiponectin receptor 1b 0.052
immt inner membrane protein, mitochondrial (mitofilin) 0.052
cdc42 cell division cycle 42 0.052
orc1 origin recognition complex, subunit 1 0.052
chia.2 chitinase, acidic.2 0.051
ctsd cathepsin D 0.051
eif3hb eukaryotic translation initiation factor 3, subunit H, b 0.051
zgc:158138 zgc:158138 0.051
tnc tenascin C 0.050
atp1b1a ATPase, Na+/K+ transporting, beta 1a polypeptide 0.050
ppp1cc protein phosphatase 1, catalytic subunit, gamma isoform 0.050
eif4e1c eukaryotic translation initiation factor 4E family member 1c 0.050
psma8 proteasome (prosome, macropain) subunit, alpha type, 8 0.049
ctsc cathepsin C 0.049
psmc5 proteasome (prosome, macropain) 26S subunit, ATPase, 5 0.049
acaa2 acetyl-CoA acyltransferase 2 0.049
rangap1 Ran GTPase activating protein 1 0.049
hmgb1a high-mobility group box 1a 0.049
trim33 tripartite motif-containing 33 0.049
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Drosophila melanogaster
Name Description Probability Func Analog Organism
Pi3K92E CG4141 gene product from transcript CG4141-RB 1.000
EcR Ecdysone receptor 0.993
Sir2 CG5216 gene product from transcript CG5216-RA 0.948
Atg8a Autophagy-specific gene 8a 0.946
dm diminutive 0.941
G-salpha60A G protein salpha 60A 0.930
Tor Target of rapamycin 0.925
CG11347 CG11347 gene product from transcript CG11347-RE 0.923
InR Insulin-like receptor 0.918
Akt1 CG4006 gene product from transcript CG4006-RA 0.909
Rheb CG1081 gene product from transcript CG1081-RA 0.906
sax saxophone 0.896
Prosbeta1 Proteasome beta1 subunit 0.881
Fmr1 CG6203 gene product from transcript CG6203-RC 0.881
SNF1A SNF1A/AMP-activated protein kinase 0.871
gig gigas 0.856
p53 CG33336 gene product from transcript CG33336-RB 0.852
Dcr-2 Dicer-2 0.840
yki yorkie 0.827
awd abnormal wing discs 0.826
Pros26.4 Proteasome 26S subunit subunit 4 ATPase 0.817
Rho1 CG8416 gene product from transcript CG8416-RB 0.813
Rpn9 CG10230 gene product from transcript CG10230-RB 0.807
shi shibire 0.807
cpa capping protein alpha 0.806
RecQ4 CG7487 gene product from transcript CG7487-RA 0.791
phl pole hole 0.779
Atg18 Autophagy-specific gene 18 0.768
CG1347 CG1347 gene product from transcript CG1347-RB 0.764
Sos Son of sevenless 0.756
dco discs overgrown 0.746
Ras85D Ras oncogene at 85D 0.744
Rpt1 CG1341 gene product from transcript CG1341-RA 0.742
CSN5 COP9 complex homolog subunit 5 0.741
Rpn11 CG18174 gene product from transcript CG18174-RA 0.740
brm brahma 0.733
Mad Mothers against dpp 0.732
rin rasputin 0.728
Rab1 Rab-protein 1 0.721
Atg2 Autophagy-specific gene 2 0.700
baz bazooka 0.692
N Notch 0.689
CG12321 CG12321 gene product from transcript CG12321-RA 0.684
Pi3K59F Phosphotidylinositol 3 kinase 59F 0.683
pie pineapple eye 0.682
Rpt3 CG16916 gene product from transcript CG16916-RA 0.675
Nup154 Nucleoporin 154 0.672
Top1 Topoisomerase 1 0.667
bsk basket 0.665
B52 CG10851 gene product from transcript CG10851-RB 0.657
rap retina aberrant in pattern 0.655
Cip4 CG15015 gene product from transcript CG15015-RA 0.655
dnc dunce 0.650
Cyp9f2 CG11466 gene product from transcript CG11466-RB 0.648
Stam Signal transducing adaptor molecule 0.644
sec15 CG7034 gene product from transcript CG7034-RA 0.641
rictor rapamycin-insensitive companion of Tor 0.641
ago archipelago 0.631
scny scrawny 0.630
Syx7 Syntaxin 7 0.627
Vps16A Vacuolar protein sorting 16A 0.623
Prosalpha5 Proteasome alpha5 subunit 0.621
egr eiger 0.618
S6k RPS6-p70-protein kinase 0.618
Prosbeta2 Proteasome beta2 subunit 0.618
Atg6 Autophagy-specific gene 6 0.617
Ugt35a UDP-glycosyltransferase 35a 0.615
eIF-4E Eukaryotic initiation factor 4E 0.611
Mnt CG13316 gene product from transcript CG13316-RD 0.610
Prosbeta3 Proteasome beta3 subunit 0.605
Rpn2 CG11888 gene product from transcript CG11888-RA 0.605
mop myopic 0.603
RASSF8 CG5053 gene product from transcript CG5053-RA 0.601
sktl skittles 0.600
Pros29 Proteasome 29kD subunit 0.598
Pkn Protein kinase related to protein kinase N 0.595
Ada2b CG9638 gene product from transcript CG9638-RA 0.595
cenG1A centaurin gamma 1A 0.595
wg wingless 0.593
LanA Laminin A 0.588
dap dacapo 0.586
Sox14 Sox box protein 14 0.584
rut rutabaga 0.583
Top2 Topoisomerase 2 0.583
hep hemipterous 0.579
Egfr Epidermal growth factor receptor 0.577
Jafrac1 thioredoxin peroxidase 1 0.568
pan pangolin 0.567
RagA CG11968 gene product from transcript CG11968-RA 0.565
Ca-P60A Calcium ATPase at 60A 0.561
msps mini spindles 0.560
RpS20 Ribosomal protein S20 0.557
ben bendless 0.551
drpr draper 0.549
raps rapsynoid 0.547
CG32479 CG32479 gene product from transcript CG32479-RA 0.541
CycB Cyclin B 0.540
Itp-r83A Inositol 1,4,5,-tris-phosphate receptor 0.534
Cat Catalase 0.529
plexB plexin B 0.524
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Homo sapiens
Name Description Probability Func Analog Organism
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Mus musculus
Name Description Probability Func Analog Organism
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Rattus norvegicus
Name Description Probability Func Analog Organism
Acadl acyl-Coenzyme A dehydrogenase, long-chain 0.847
Decr1 2,4-dienoyl CoA reductase 1, mitochondrial 0.842
Psma5 proteasome (prosome, macropain) subunit, alpha type 5 0.792
Psmc2 proteasome (prosome, macropain) 26S subunit, ATPase 2 0.783
Ugt2b UDP glycosyltransferase 2 family, polypeptide B 0.731
Cyp2b1 cytochrome P450, family 2, subfamily b, polypeptide 1 0.726
Ech1 enoyl coenzyme A hydratase 1, peroxisomal 0.713
Psma3 proteasome (prosome, macropain) subunit, alpha type 3 0.710
Acaa2 acetyl-Coenzyme A acyltransferase 2 0.660
Psmb3 proteasome (prosome, macropain) subunit, beta type 3 0.646
Pebp1 phosphatidylethanolamine binding protein 1 0.636
Gstm1 glutathione S-transferase mu 1 0.634
Hk1 hexokinase 1 0.633
Apob apolipoprotein B 0.625
Kmo kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) 0.608
Ctsl1 cathepsin L1 0.587
Ugt1a6 UDP glucuronosyltransferase 1 family, polypeptide A6 0.584
Cyp3a18 cytochrome P450, family 3, subfamily a, polypeptide 18 0.577
Mapre1 microtubule-associated protein, RP/EB family, member 1 0.555
Ppm1a protein phosphatase 1A, magnesium dependent, alpha isoform 0.547
Lamp2 lysosomal-associated membrane protein 2 0.542
Acadvl acyl-Coenzyme A dehydrogenase, very long chain 0.520
Cyp2d4 cytochrome P450, family 2, subfamily d, polypeptide 4 0.517
Psmc1 proteasome (prosome, macropain) 26S subunit, ATPase, 1 0.516
Dnm1l dynamin 1-like 0.506
Psmb4 proteasome (prosome, macropain) subunit, beta type 4 0.488
Suclg1 succinate-CoA ligase, alpha subunit 0.482
Rab1 RAB1, member RAS oncogene family 0.470
Papola poly (A) polymerase alpha 0.465
Ppp2ca protein phosphatase 2, catalytic subunit, alpha isoform 0.458
Casp3 caspase 3 0.447
Etfa electron-transfer-flavoprotein, alpha polypeptide 0.444
Tap2 transporter 2, ATP-binding cassette, sub-family B (MDR/TAP) 0.443
Psma7 proteasome (prosome, macropain) subunit, alpha type 7 0.442
LOC293989 cytochrome P450-like 0.442
Acox1 acyl-Coenzyme A oxidase 1, palmitoyl 0.437
Psmd4 proteasome (prosome, macropain) 26S subunit, non-ATPase, 4 0.437
Acadm acyl-Coenzyme A dehydrogenase, C-4 to C-12 straight chain 0.434
Slc2a4 solute carrier family 2 (facilitated glucose transporter), member 4 0.429
Dnajc5 DnaJ (Hsp40) homolog, subfamily C, member 5 0.429
Hsp90ab1 heat shock protein 90 alpha (cytosolic), class B member 1 0.420
Hadhb hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenzyme A hydratase (trifunctional protein), beta subunit 0.414
Eif5 eukaryotic translation initiation factor 5 0.412
Mgst2 microsomal glutathione S-transferase 2 0.407
Exoc5 exocyst complex component 5 0.400
Ube2g1 ubiquitin-conjugating enzyme E2G 1 (UBC7 homolog, yeast) 0.397
Cyp4a3 cytochrome P450, family 4, subfamily a, polypeptide 3 0.390
Acat1 acetyl-coenzyme A acetyltransferase 1 0.388
Tnfrsf1a tumor necrosis factor receptor superfamily, member 1a 0.384
Flt1 FMS-related tyrosine kinase 1 0.382
Hsd17b4 hydroxysteroid (17-beta) dehydrogenase 4 0.380
Slc25a20 solute carrier family 25 (carnitine/acylcarnitine translocase), member 20 0.380
Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 0.380
Klf6 Kruppel-like factor 6 0.371
Acads acyl-Coenzyme A dehydrogenase, C-2 to C-3 short chain 0.370
Anxa2 annexin A2 0.367
LOC494499 LOC494499 protein 0.366
Ces1c carboxylesterase 1C 0.363
Ifitm3 interferon induced transmembrane protein 3 0.358
Mgst1 microsomal glutathione S-transferase 1 0.354
Cpt2 carnitine palmitoyltransferase 2 0.353
Gabrg1 gamma-aminobutyric acid (GABA) A receptor, gamma 1 0.352
Pros1 protein S (alpha) 0.351
Etfdh electron-transferring-flavoprotein dehydrogenase 0.351
Abcc2 ATP-binding cassette, subfamily C (CFTR/MRP), member 2 0.348
Acot2 acyl-CoA thioesterase 2 0.346
Pls3 plastin 3 (T-isoform) 0.339
Ntrk1 neurotrophic tyrosine kinase, receptor, type 1 0.337
Ucp2 uncoupling protein 2 (mitochondrial, proton carrier) 0.337
Hmgcs2 3-hydroxy-3-methylglutaryl-Coenzyme A synthase 2 (mitochondrial) 0.336
Nsf N-ethylmaleimide-sensitive factor 0.334
Gria2 glutamate receptor, ionotropic, AMPA 2 0.331
Cyp4a2 cytochrome P450, family 4, subfamily a, polypeptide 2 0.329
Gsta5 glutathione S-transferase Yc2 subunit 0.327
Prdx1 peroxiredoxin 1 0.325
Myo1b myosin Ib 0.321
Ccnd3 cyclin D3 0.314
Crot carnitine O-octanoyltransferase 0.310
Tpm4 tropomyosin 4 0.307
Cmklr1 chemokine-like receptor 1 0.306
Pck1 phosphoenolpyruvate carboxykinase 1 (soluble) 0.305
Lman1 lectin, mannose-binding, 1 0.303
Psmc5 proteasome (prosome, macropain) 26S subunit, ATPase, 5 0.294
Cyp2c22 cytochrome P450, family 2, subfamily c, polypeptide 22 0.293
Cox4i1 cytochrome c oxidase subunit IV isoform 1 0.292
Dnaja1 DnaJ (Hsp40) homolog, subfamily A, member 1 0.290
Rab11a RAB11a, member RAS oncogene family 0.289
Cyp4a10 cytochrome P450, family 4, subfamily a, polypeptide 10 0.288
Ftl ferritin, light polypeptide 0.287
Adar adenosine deaminase, RNA-specific 0.286
Pik3cd phosphoinositide-3-kinase, catalytic, delta polypeptide 0.284
MGC112883 LOC500651 0.281
Gdi2 GDP dissociation inhibitor 2 0.274
Cyp2b15 cytochrome P450, family 2, subfamily b, polypeptide 15 0.273
Flnb filamin, beta 0.272
Pdia4 protein disulfide isomerase family A, member 4 0.272
Nae1 NEDD8 activating enzyme E1 subunit 1 0.271
B2m beta-2 microglobulin 0.269
Ces1e carboxylesterase 1E 0.268
Cyp2b2 cytochrome P450, family 2, subfamily b, polypeptide 2 0.267
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism