Process View
The network for 'dna catabolic process' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.
The cellular DNA metabolic process resulting in the breakdown of DNA, deoxyribonucleic acid, one of the two main types of nucleic acid, consisting of a long unbranched macromolecule formed from one or two strands of linked deoxyribonucleotides, the 3'-phosphate group of each constituent deoxyribonucleotide being joined in 3',5'-phosphodiester linkage to the 5'-hydroxyl group of the deoxyribose moiety of the next one.
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| RAD1 | Rad1p | 0.804 | |
| XRS2 | Xrs2p | 0.602 | |
| RAD10 | Rad10p | 0.486 | |
| RAD59 | Rad59p | 0.436 | |
| MSH2 | Msh2p | 0.417 | |
| RAD14 | Rad14p | 0.216 | |
| ASF1 | Asf1p | 0.191 | |
| RAD18 | Rad18p | 0.180 | |
| MLH1 | Mlh1p | 0.174 | |
| RAD52 | Rad52p | 0.167 | |
| TEL1 | Tel1p | 0.129 | |
| RFA1 | Rfa1p | 0.129 | |
| RAD53 | Rad53p | 0.109 | |
| RFA3 | Rfa3p | 0.108 | |
| MRC1 | Mrc1p | 0.107 | |
| MSH3 | Msh3p | 0.101 | |
| POL32 | Pol32p | 0.091 | |
| EXO1 | Exo1p | 0.089 | |
| RAD2 | Rad2p | 0.088 | |
| MEC1 | Mec1p | 0.082 | |
| RAD5 | Rad5p | 0.075 | |
| ULP1 | Ulp1p | 0.065 | |
| MMS1 | Mms1p | 0.064 | |
| DNA2 | Dna2p | 0.063 | |
| SAW1 | Saw1p | 0.063 | |
| HDA2 | Hda2p | 0.062 | |
| MSH6 | Msh6p | 0.062 | |
| REV3 | Rev3p | 0.059 | |
| SLX4 | Slx4p | 0.054 | |
| PMS1 | Pms1p | 0.054 | |
| SEN1 | Sen1p | 0.049 | |
| MGS1 | Mgs1p | 0.049 | |
| SAE2 | Sae2p | 0.047 | |
| TIM44 | Tim44p | 0.047 | |
| THO2 | Tho2p | 0.044 | |
| SIR3 | Sir3p | 0.042 | |
| NTG1 | Ntg1p | 0.042 | |
| RPS5 | Rps5p | 0.041 | |
| TOP1 | Top1p | 0.041 | |
| RMI1 | Rmi1p | 0.038 | |
| RAD16 | Rad16p | 0.037 | |
| PIF1 | Pif1p | 0.035 | |
| MUS81 | Mus81p | 0.035 | |
| JHD2 | Jhd2p | 0.034 | |
| RAD26 | Rad26p | 0.033 | |
| CAK1 | Cak1p | 0.032 | |
| MDJ1 | Mdj1p | 0.032 | |
| YLR264C-A | hypothetical protein | 0.032 | |
| SGS1 | Sgs1p | 0.032 | |
| APN2 | Apn2p | 0.032 | |
| RAD7 | Rad7p | 0.031 | |
| MPH1 | Mph1p | 0.031 | |
| SIS2 | Sis2p | 0.031 | |
| RLF2 | Rlf2p | 0.031 | |
| YBL044W | hypothetical protein | 0.030 | |
| ADI1 | Adi1p | 0.030 | |
| APN1 | Apn1p | 0.030 | |
| DUN1 | Dun1p | 0.030 | |
| RAD17 | Rad17p | 0.029 | |
| SRD1 | Srd1p | 0.029 | |
| NTA1 | Nta1p | 0.029 | |
| URA6 | Ura6p | 0.029 | |
| SMC6 | Smc6p | 0.028 | |
| YLR419W | hypothetical protein | 0.028 | |
| PSO2 | Pso2p | 0.028 | |
| ALT2 | Alt2p | 0.027 | |
| LEU2 | Leu2p | 0.027 | |
| YLR162W | hypothetical protein | 0.027 | |
| RPL7B | Rpl7bp | 0.026 | |
| YOL038C-A | hypothetical protein | 0.026 | |
| YPL068C | hypothetical protein | 0.026 | |
| HO | Hop | 0.025 | |
| YAR068W | hypothetical protein | 0.025 | |
| DOT1 | Dot1p | 0.025 | |
| PET309 | Pet309p | 0.025 | |
| GYL1 | Gyl1p | 0.025 | |
| YIR035C | hypothetical protein | 0.025 | |
| POM34 | Pom34p | 0.025 | |
| URA3 | Ura3p | 0.024 | |
| ARG8 | Arg8p | 0.024 | |
| LIF1 | Lif1p | 0.024 | |
| CUP1-1 | Cup1-1p | 0.024 | |
| UGO1 | Ugo1p | 0.024 | |
| MER1 | Mer1p | 0.024 | |
| RAD24 | Rad24p | 0.023 | |
| YLR363W-A | hypothetical protein | 0.023 | |
| SHU1 | Shu1p | 0.023 | |
| SUT2 | Sut2p | 0.023 | |
| MMS4 | Mms4p | 0.023 | |
| CLN2 | Cln2p | 0.023 | |
| YPL260W | hypothetical protein | 0.023 | |
| REV1 | Rev1p | 0.022 | |
| PTP3 | Ptp3p | 0.022 | |
| KTI12 | Kti12p | 0.022 | |
| SOM1 | Som1p | 0.022 | |
| THP2 | Thp2p | 0.022 | |
| POL31 | Pol31p | 0.022 | |
| HST3 | Hst3p | 0.021 | |
| ATP6 | Atp6p | 0.021 | |
| YBR013C | hypothetical protein | 0.021 |
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| mcm5 | MCM5 minichromosome maintenance deficient 5 (S. cerevisiae) | 0.863 | |
| pcna | proliferating cell nuclear antigen | 0.789 | |
| prim1 | primase polypeptide 1 | 0.393 | |
| rrm1 | ribonucleotide reductase M1 polypeptide | 0.267 | |
| setdb1a | SET domain, bifurcated 1a | 0.256 | |
| zgc:103564 | zgc:103564 | 0.219 | |
| bactin1 | bactin1 | 0.201 | |
| brip1 | BRCA1 interacting protein C-terminal helicase 1 | 0.199 | |
| ccnd1 | cyclin D1 | 0.174 | |
| tyms | thymidylate synthase | 0.168 | |
| si:ch211-1n9.7 | si:ch211-1n9.7 | 0.160 | |
| zgc:101661 | zgc:101661 | 0.159 | |
| msh2 | mutS homolog 2 (E. coli) | 0.157 | |
| npat | nuclear protein, ataxia-telangiectasia locus | 0.148 | |
| slbp | stem-loop binding protein | 0.140 | |
| mcm4 | MCM4 minichromosome maintenance deficient 4, mitotin (S. cerevisiae) | 0.140 | |
| dut | dUTP pyrophosphatase | 0.128 | |
| mybl2 | myeloblastosis oncogene-like 2 | 0.126 | |
| hnrnpa1 | heterogeneous nuclear ribonucleoprotein A1 | 0.120 | |
| palb2 | partner and localizer of BRCA2 | 0.120 | |
| myca | myelocytomatosis oncogene a | 0.118 | |
| rac1 | ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) | 0.111 | |
| srm | spermidine synthase | 0.089 | |
| zgc:77165 | zgc:77165 | 0.084 | |
| dhfr | dihydrofolate reductase | 0.084 | |
| pola2 | polymerase (DNA directed), alpha 2 | 0.079 | |
| aldh1a2 | aldehyde dehydrogenase 1 family, member A2 | 0.078 | |
| chek2 | CHK2 checkpoint homolog (S. pombe) | 0.078 | |
| rpa1 | replication protein A1 | 0.076 | |
| ncapd2 | non-SMC condensin I complex, subunit D2 | 0.075 | |
| prmt1 | protein arginine methyltransferase 1 | 0.072 | |
| hnrnpa0 | heterogeneous nuclear ribonucleoprotein A0 | 0.072 | |
| ptger4a | prostaglandin E receptor 4 (subtype EP4) a | 0.071 | |
| ppm1g | protein phosphatase 1G (formerly 2C), magnesium-dependent, gamma isoform | 0.070 | |
| lrrc42 | leucine rich repeat containing 42 | 0.069 | |
| zgc:92661 | zgc:92661 | 0.064 | |
| ncapg | non-SMC condensin I complex, subunit G | 0.062 | |
| ipo9 | importin 9 | 0.061 | |
| ywhae1 | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide 1 | 0.058 | |
| wdhd1 | WD repeat and HMG-box DNA binding protein 1 | 0.058 | |
| ccng1 | cyclin G1 | 0.057 | |
| cdc7 | cell division cycle 7 homolog (S. cerevisiae) | 0.057 | |
| zgc:110113 | zgc:110113 | 0.056 | |
| mus81 | MUS81 endonuclease homolog (yeast) | 0.056 | |
| racgap1 | Rac GTPase-activating protein 1 | 0.056 | |
| zff9 | zinc finger protein 9 | 0.055 | |
| kif14 | kinesin family member 14 | 0.054 | |
| fen1 | flap structure-specific endonuclease 1 | 0.053 | |
| efna2 | ephrin A2 | 0.052 | |
| zgc:92648 | zgc:92648 | 0.052 | |
| zgc:56197 | zgc:56197 | 0.052 | |
| LOC560606 | novel protein similar to human and mouse leishmanolysin-like (metallopeptidase M8 family) (LMLN) | 0.048 | |
| cdc45 | CDC45 cell division cycle 45 homolog (S. cerevisiae) | 0.048 | |
| hells | helicase, lymphoid-specific | 0.048 | |
| dnmt1 | DNA (cytosine-5-)-methyltransferase 1 | 0.047 | |
| chtf18 | CTF18, chromosome transmission fidelity factor 18 homolog (S. cerevisiae) | 0.047 | |
| arpc5a | actin related protein 2/3 complex, subunit 5A | 0.044 | |
| tp53 | tumor protein p53 | 0.043 | |
| setd8a | SET domain containing (lysine methyltransferase) 8a | 0.043 | |
| bcl2l1 | bcl2-like 1 | 0.043 | |
| hgfa | hepatocyte growth factor a | 0.042 | |
| arid4a | AT rich interactive domain 4A (RBP1-like) | 0.042 | |
| pomgnt1 | protein O-linked mannose beta1,2-N-acetylglucosaminyltransferase | 0.041 | |
| pole3 | polymerase (DNA directed), epsilon 3 (p17 subunit) | 0.041 | |
| gins1 | GINS complex subunit 1 (Psf1 homolog) | 0.040 | |
| eif4e | eukaryotic translation initiation factor 4e | 0.040 | |
| ncaph | non-SMC condensin I complex, subunit H | 0.040 | |
| cep70 | centrosomal protein 70 | 0.039 | |
| zgc:152930 | zgc:152930 | 0.038 | |
| anapc5 | anaphase promoting complex subunit 5 | 0.038 | |
| si:ch211-254d18.3 | si:ch211-254d18.3 | 0.038 | |
| rad51c | rad51 homolog C (S. cerevisiae) | 0.037 | |
| aldh7a1 | aldehyde dehydrogenase 7 family, member A1 | 0.037 | |
| ilf2 | interleukin enhancer binding factor 2 | 0.037 | |
| wdr76 | WD repeat domain 76 | 0.037 | |
| zgc:112425 | zgc:112425 | 0.036 | |
| arf2 | ADP-ribosylation factor 2 | 0.036 | |
| zgc:110540 | zgc:110540 | 0.036 | |
| nipblb | novel protein similar to vertebrate Nipped-B homolog and nipped-b homolog b (Drosophila) | 0.035 | |
| fcer1g | Fc receptor, IgE, high affinity I, gamma polypeptide | 0.035 | |
| ssb | Sjogren syndrome antigen B (autoantigen La) | 0.035 | |
| arntl2 | aryl hydrocarbon receptor nuclear translocator-like 2 | 0.035 | |
| hsp90b1 | heat shock protein 90, beta (grp94), member 1 | 0.035 | |
| anp32b | acidic (leucine-rich) nuclear phosphoprotein 32 family, member B | 0.034 | |
| ankrd49 | ankyrin repeat domain 49 | 0.034 | |
| setb | SET translocation (myeloid leukemia-associated) B | 0.033 | |
| rnasen | ribonuclease type III, nuclear | 0.033 | |
| zgc:154089 | zgc:154089 | 0.033 | |
| ddx20 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 20 | 0.032 | |
| esco2 | establishment of cohesion 1 homolog 2 | 0.030 | |
| apex1 | APEX nuclease (multifunctional DNA repair enzyme) 1 | 0.030 | |
| sephs1 | selenophosphate synthetase 1 | 0.030 | |
| tgfb3 | transforming growth factor, beta 3 | 0.029 | |
| cdk2 | cyclin-dependent kinase 2 | 0.029 | |
| fabp7a | fatty acid binding protein 7, brain, a | 0.029 | |
| tuba1 | tubulin, alpha 1 | 0.029 | |
| zgc:100817 | zgc:100817 | 0.029 | |
| rfc4 | replication factor C (activator 1) 4 | 0.029 | |
| ck2b | casein kinase 2 beta | 0.029 | |
| rad51l1 | RAD51-like 1 (S. cerevisiae) | 0.029 |
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| mus301 | mutagen-sensitive 301 | 0.144 | |
| spn-B | spindle B | 0.132 | |
| mei-9 | meiotic 9 | 0.101 | |
| Smc5 | CG32438 gene product from transcript CG32438-RE | 0.077 | |
| mus205 | mutagen-sensitive 205 | 0.067 | |
| Brca2 | Breast cancer 2, early onset homolog | 0.046 | |
| spn-E | spindle E | 0.044 | |
| Mcm5 | Minichromosome maintenance 5 | 0.035 | |
| mus304 | mutagen-sensitive 304 | 0.034 | |
| CG4973 | CG4973 gene product from transcript CG4973-RA | 0.033 | |
| lok | loki | 0.029 | |
| nbs | CG6754 gene product from transcript CG6754-RC | 0.029 | |
| mus101 | mutagen-sensitive 101 | 0.027 | |
| step | steppke | 0.023 | |
| spn-A | spindle A | 0.021 | |
| Eb1 | CG3265 gene product from transcript CG3265-RF | 0.021 | |
| p53 | CG33336 gene product from transcript CG33336-RB | 0.019 | |
| Patr-1 | Protein associated with topo II related - 1 | 0.019 | |
| Dcp-1 | Death caspase-1 | 0.018 | |
| CG9752 | CG9752 gene product from transcript CG9752-RA | 0.017 | |
| Cks30A | Cyclin-dependent kinase subunit 30A | 0.017 | |
| ranshi | CG9793 gene product from transcript CG9793-RA | 0.017 | |
| CG11164 | CG11164 gene product from transcript CG11164-RA | 0.016 | |
| MAGE | CG10059 gene product from transcript CG10059-RA | 0.015 | |
| Df31 | Decondensation factor 31 | 0.015 | |
| Nc | Nedd2-like caspase | 0.013 | |
| RhoGAP92B | CG4755 gene product from transcript CG4755-RA | 0.013 | |
| cav | caravaggio | 0.013 | |
| mus201 | mutagen-sensitive 201 | 0.013 | |
| CG5524 | CG5524 gene product from transcript CG5524-RA | 0.012 | |
| tefu | telomere fusion | 0.012 | |
| Mcm7 | Minichromosome maintenance 7 | 0.011 | |
| okr | okra | 0.011 | |
| CG9247 | CG9247 gene product from transcript CG9247-RA | 0.011 | |
| AGO3 | Argonaute 3 | 0.011 | |
| Klp3A | Kinesin-like protein at 3A | 0.011 | |
| orb | oo18 RNA-binding protein | 0.010 | |
| CG5602 | CG5602 gene product from transcript CG5602-RA | 0.010 | |
| CG10638 | CG10638 gene product from transcript CG10638-RA | 0.010 |
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| SLX4 | SLX4 structure-specific endonuclease subunit homolog (S. cerevisiae) | 0.998 | |
| MSH2 | mutS homolog 2, colon cancer, nonpolyposis type 1 (E. coli) | 0.998 | |
| BRCA1 | breast cancer 1, early onset | 0.991 | |
| XRCC6 | X-ray repair complementing defective repair in Chinese hamster cells 6 | 0.945 | |
| CHEK1 | CHK1 checkpoint homolog (S. pombe) | 0.931 | |
| EME1 | essential meiotic endonuclease 1 homolog 1 (S. pombe) | 0.916 | |
| TP53 | tumor protein p53 | 0.893 | |
| XRCC5 | X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) | 0.880 | |
| MUS81 | MUS81 endonuclease homolog (S. cerevisiae) | 0.878 | |
| BAK1 | BCL2-antagonist/killer 1 | 0.793 | |
| H2AFX | H2A histone family, member X | 0.780 | |
| BCL2L1 | BCL2-like 1 | 0.748 | |
| RAD51 | RAD51 homolog (RecA homolog, E. coli) (S. cerevisiae) | 0.738 | |
| DFFA | DNA fragmentation factor, 45kDa, alpha polypeptide | 0.725 | |
| CASP9 | caspase 9, apoptosis-related cysteine peptidase | 0.713 | |
| SLX1B | SLX1 structure-specific endonuclease subunit homolog B (S. cerevisiae) | 0.713 | |
| RAD50 | RAD50 homolog (S. cerevisiae) | 0.697 | |
| BCL2 | B-cell CLL/lymphoma 2 | 0.674 | |
| PMS2 | PMS2 postmeiotic segregation increased 2 (S. cerevisiae) | 0.637 | |
| MSH6 | mutS homolog 6 (E. coli) | 0.604 | |
| EXOSC3 | exosome component 3 | 0.577 | |
| E2F1 | E2F transcription factor 1 | 0.512 | |
| BLM | Bloom syndrome, RecQ helicase-like | 0.497 | |
| NBN | nibrin | 0.432 | |
| PARP1 | poly (ADP-ribose) polymerase 1 | 0.416 | |
| DFFB | DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase) | 0.414 | |
| GNLY | granulysin | 0.400 | |
| MRE11A | MRE11 meiotic recombination 11 homolog A (S. cerevisiae) | 0.354 | |
| BAX | BCL2-associated X protein | 0.353 | |
| C20orf94 | chromosome 20 open reading frame 94 | 0.339 | |
| WRN | Werner syndrome, RecQ helicase-like | 0.332 | |
| VDAC1 | voltage-dependent anion channel 1 | 0.293 | |
| MCL1 | myeloid cell leukemia sequence 1 (BCL2-related) | 0.282 | |
| CHEK2 | CHK2 checkpoint homolog (S. pombe) | 0.271 | |
| MLH1 | mutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli) | 0.242 | |
| EXOSC10 | exosome component 10 | 0.241 | |
| POU5F1 | POU class 5 homeobox 1 | 0.213 | |
| DIS3 | DIS3 mitotic control homolog (S. cerevisiae) | 0.201 | |
| XIAP | X-linked inhibitor of apoptosis | 0.198 | |
| XRCC1 | X-ray repair complementing defective repair in Chinese hamster cells 1 | 0.196 | |
| BRCA2 | breast cancer 2, early onset | 0.151 | |
| FANCD2 | Fanconi anemia, complementation group D2 | 0.149 | |
| C19orf39 | chromosome 19 open reading frame 39 | 0.149 | |
| UBE2V1 | ubiquitin-conjugating enzyme E2 variant 1 | 0.145 | |
| RAD1 | RAD1 homolog (S. pombe) | 0.144 | |
| MDM2 | Mdm2 p53 binding protein homolog (mouse) | 0.139 | |
| PCNA | proliferating cell nuclear antigen | 0.139 | |
| CCT2 | chaperonin containing TCP1, subunit 2 (beta) | 0.138 | |
| HSPA8 | heat shock 70kDa protein 8 | 0.137 | |
| EXO1 | exonuclease 1 | 0.135 | |
| XRCC4 | X-ray repair complementing defective repair in Chinese hamster cells 4 | 0.128 | |
| ATM | ataxia telangiectasia mutated | 0.126 | |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.114 | |
| XPC | xeroderma pigmentosum, complementation group C | 0.112 | |
| MDC1 | mediator of DNA-damage checkpoint 1 | 0.112 | |
| PRMT6 | protein arginine methyltransferase 6 | 0.111 | |
| RAD52 | RAD52 homolog (S. cerevisiae) | 0.104 | |
| RPA1 | replication protein A1, 70kDa | 0.101 | |
| CDK2 | cyclin-dependent kinase 2 | 0.100 | |
| BCL2L11 | BCL2-like 11 (apoptosis facilitator) | 0.095 | |
| EXOSC7 | exosome component 7 | 0.094 | |
| ERCC4 | excision repair cross-complementing rodent repair deficiency, complementation group 4 | 0.077 | |
| PRF1 | perforin 1 (pore forming protein) | 0.076 | |
| TERF2IP | telomeric repeat binding factor 2, interacting protein | 0.075 | |
| RAD18 | RAD18 homolog (S. cerevisiae) | 0.074 | |
| MCM10 | minichromosome maintenance complex component 10 | 0.074 | |
| TELO2 | TEL2, telomere maintenance 2, homolog (S. cerevisiae) | 0.073 | |
| EIF2C1 | eukaryotic translation initiation factor 2C, 1 | 0.071 | |
| PHB | prohibitin | 0.070 | |
| HUWE1 | HECT, UBA and WWE domain containing 1 | 0.069 | |
| ERCC1 | excision repair cross-complementing rodent repair deficiency, complementation group 1 (includes overlapping antisense sequence) | 0.069 | |
| C4orf14 | chromosome 4 open reading frame 14 | 0.067 | |
| RNR2 | l-rRNA | 0.065 | |
| MSH3 | mutS homolog 3 (E. coli) | 0.064 | |
| CCNE1 | cyclin E1 | 0.064 | |
| EXOSC4 | exosome component 4 | 0.056 | |
| PRKRA | protein kinase, interferon-inducible double stranded RNA dependent activator | 0.056 | |
| PARP2 | poly (ADP-ribose) polymerase 2 | 0.056 | |
| RCC1 | regulator of chromosome condensation 1 | 0.055 | |
| TARBP2 | TAR (HIV-1) RNA binding protein 2 | 0.053 | |
| NUDT1 | nudix (nucleoside diphosphate linked moiety X)-type motif 1 | 0.052 | |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | 0.050 | |
| NCL | nucleolin | 0.049 | |
| EXOSC8 | exosome component 8 | 0.049 | |
| CLSPN | claspin | 0.048 | |
| EXOSC5 | exosome component 5 | 0.048 | |
| MOCS3 | molybdenum cofactor synthesis 3 | 0.048 | |
| MYCN | v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian) | 0.048 | |
| CASP3 | caspase 3, apoptosis-related cysteine peptidase | 0.047 | |
| PNKP | polynucleotide kinase 3'-phosphatase | 0.047 | |
| EP300 | E1A binding protein p300 | 0.045 | |
| NME2 | non-metastatic cells 2, protein (NM23B) expressed in | 0.045 | |
| POLQ | polymerase (DNA directed), theta | 0.045 | |
| POLD3 | polymerase (DNA-directed), delta 3, accessory subunit | 0.044 | |
| RECQL4 | RecQ protein-like 4 | 0.043 | |
| SOX2 | SRY (sex determining region Y)-box 2 | 0.043 | |
| TOMM22 | translocase of outer mitochondrial membrane 22 homolog (yeast) | 0.043 | |
| HSPA1B | heat shock 70kDa protein 1B | 0.043 | |
| RBL1 | retinoblastoma-like 1 (p107) | 0.042 | |
| FEN1 | flap structure-specific endonuclease 1 | 0.041 |
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| Rb1 | retinoblastoma 1 | 0.773 | |
| Brca1 | breast cancer 1 | 0.763 | |
| Brca2 | breast cancer 2 | 0.534 | |
| Dffb | DNA fragmentation factor, beta subunit | 0.499 | |
| Cdk4 | cyclin-dependent kinase 4 | 0.385 | |
| Trp53 | transformation related protein 53 | 0.360 | |
| Ppp1cc | protein phosphatase 1, catalytic subunit, gamma isoform | 0.330 | |
| Prkdc | protein kinase, DNA activated, catalytic polypeptide | 0.267 | |
| Nbn | nibrin | 0.197 | |
| Casp1 | caspase 1 | 0.166 | |
| Ccne1 | cyclin E1 | 0.164 | |
| Casp4 | caspase 4, apoptosis-related cysteine peptidase | 0.150 | |
| Cdkn1b | cyclin-dependent kinase inhibitor 1B | 0.116 | |
| Hells | helicase, lymphoid specific | 0.112 | |
| Gbp5 | guanylate binding protein 5 | 0.104 | |
| Hspd1 | heat shock protein 1 (chaperonin) | 0.083 | |
| Ccnd1 | cyclin D1 | 0.076 | |
| Hdac1 | histone deacetylase 1 | 0.075 | |
| Il18 | interleukin 18 | 0.072 | |
| Wdhd1 | WD repeat and HMG-box DNA binding protein 1 | 0.071 | |
| Cdc6 | cell division cycle 6 homolog (S. cerevisiae) | 0.070 | |
| Map3k7 | mitogen-activated protein kinase kinase kinase 7 | 0.069 | |
| Atm | ataxia telangiectasia mutated homolog (human) | 0.066 | |
| Terf1 | telomeric repeat binding factor 1 | 0.064 | |
| Pycard | PYD and CARD domain containing | 0.063 | |
| Ppp1ca | protein phosphatase 1, catalytic subunit, alpha isoform | 0.063 | |
| Rfc3 | replication factor C (activator 1) 3 | 0.062 | |
| Orc1 | origin recognition complex, subunit 1 | 0.060 | |
| Rbl1 | retinoblastoma-like 1 (p107) | 0.055 | |
| Pms2 | postmeiotic segregation increased 2 (S. cerevisiae) | 0.053 | |
| Atr | ataxia telangiectasia and Rad3 related | 0.053 | |
| Igh | immunoglobulin heavy chain complex | 0.048 | |
| Mis18bp1 | MIS18 binding protein 1 | 0.046 | |
| Ezh2 | enhancer of zeste homolog 2 (Drosophila) | 0.046 | |
| Dtl | denticleless homolog (Drosophila) | 0.044 | |
| Tlr4 | toll-like receptor 4 | 0.043 | |
| Nphp4 | nephronophthisis 4 (juvenile) homolog (human) | 0.043 | |
| Mdm2 | transformed mouse 3T3 cell double minute 2 | 0.042 | |
| Casp3 | caspase 3 | 0.040 | |
| Kiss1 | KiSS-1 metastasis-suppressor | 0.039 | |
| Tgfbr2 | transforming growth factor, beta receptor II | 0.039 | |
| Dicer1 | Dicer1, Dcr-1 homolog (Drosophila) | 0.039 | |
| Nasp | nuclear autoantigenic sperm protein (histone-binding) | 0.039 | |
| Plk4 | polo-like kinase 4 (Drosophila) | 0.037 | |
| Cdk2 | cyclin-dependent kinase 2 | 0.037 | |
| Plin1 | perilipin 1 | 0.037 | |
| Pole2 | polymerase (DNA directed), epsilon 2 (p59 subunit) | 0.036 | |
| Mcm4 | minichromosome maintenance deficient 4 homolog (S. cerevisiae) | 0.036 | |
| Lrpprc | leucine-rich PPR-motif containing | 0.035 | |
| Ndufab1 | NADH dehydrogenase (ubiquinone) 1, alpha/beta subcomplex, 1 | 0.035 | |
| Bub1 | budding uninhibited by benzimidazoles 1 homolog (S. cerevisiae) | 0.035 | |
| Apc | adenomatosis polyposis coli | 0.033 | |
| Drosha | drosha, ribonuclease type III | 0.033 | |
| Mlh1 | mutL homolog 1 (E. coli) | 0.032 | |
| Chek2 | CHK2 checkpoint homolog (S. pombe) | 0.032 | |
| Cdca7l | cell division cycle associated 7 like | 0.032 | |
| Il1b | interleukin 1 beta | 0.032 | |
| Parp2 | poly (ADP-ribose) polymerase family, member 2 | 0.031 | |
| Lig4 | ligase IV, DNA, ATP-dependent | 0.030 | |
| Bak1 | BCL2-antagonist/killer 1 | 0.029 | |
| Stk11 | serine/threonine kinase 11 | 0.029 | |
| Wrn | Werner syndrome homolog (human) | 0.029 | |
| Xpa | xeroderma pigmentosum, complementation group A | 0.028 | |
| Fadd | Fas (TNFRSF6)-associated via death domain | 0.027 | |
| Pola1 | polymerase (DNA directed), alpha 1 | 0.027 | |
| Suz12 | suppressor of zeste 12 homolog (Drosophila) | 0.027 | |
| Tfam | transcription factor A, mitochondrial | 0.026 | |
| Cycs | cytochrome c, somatic | 0.026 | |
| Trip13 | thyroid hormone receptor interactor 13 | 0.026 | |
| Mcm7 | minichromosome maintenance deficient 7 (S. cerevisiae) | 0.025 | |
| Fen1 | flap structure specific endonuclease 1 | 0.025 | |
| Kif11 | kinesin family member 11 | 0.024 | |
| Cenpk | centromere protein K | 0.024 | |
| Srsf9 | serine/arginine-rich splicing factor 9 | 0.024 | |
| Ccna2 | cyclin A2 | 0.024 | |
| Prkab1 | protein kinase, AMP-activated, beta 1 non-catalytic subunit | 0.023 | |
| Ccnb1 | cyclin B1 | 0.023 | |
| Mdm4 | transformed mouse 3T3 cell double minute 4 | 0.023 | |
| Timm8a1 | translocase of inner mitochondrial membrane 8 homolog a1 (yeast) | 0.023 | |
| Dhfr | dihydrofolate reductase | 0.023 | |
| Ranbp1 | RAN binding protein 1 | 0.022 | |
| Smc2 | structural maintenance of chromosomes 2 | 0.022 | |
| Ikbkb | inhibitor of kappaB kinase beta | 0.022 | |
| E2f1 | E2F transcription factor 1 | 0.021 | |
| Hist1h1a | histone cluster 1, H1a | 0.021 | |
| Gmnn | geminin | 0.021 | |
| Ndufaf4 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, assembly factor 4 | 0.021 | |
| Ints9 | integrator complex subunit 9 | 0.020 | |
| Rttn | rotatin | 0.020 | |
| Chek1 | checkpoint kinase 1 homolog (S. pombe) | 0.020 | |
| Dsn1 | DSN1, MIND kinetochore complex component, homolog (S. cerevisiae) | 0.020 | |
| Impdh2 | inosine 5'-phosphate dehydrogenase 2 | 0.020 | |
| Cdc7 | cell division cycle 7 (S. cerevisiae) | 0.020 | |
| Mybl2 | myeloblastosis oncogene-like 2 | 0.020 | |
| Ikbkg | inhibitor of kappaB kinase gamma | 0.020 | |
| Prim1 | DNA primase, p49 subunit | 0.019 | |
| Cox5a | cytochrome c oxidase, subunit Va | 0.019 | |
| Nlrp3 | NLR family, pyrin domain containing 3 | 0.019 | |
| Mcm10 | minichromosome maintenance deficient 10 (S. cerevisiae) | 0.019 | |
| Ccdc99 | coiled-coil domain containing 99 | 0.019 |