The network for 'regulation of sodium ion transmembrane transport' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

regulation of sodium ion transmembrane transport

Any process that modulates the frequency, rate or extent of sodium ion transmembrane transport.

Danio rerio
Name Description Probability Func Analog Organism
atp1b3b ATPase, Na+/K+ transporting, beta 3b polypeptide 0.456
gad1b glutamate decarboxylase 1b 0.238
gapdhs glyceraldehyde-3-phosphate dehydrogenase, spermatogenic 0.153
eno1 enolase 1, (alpha) 0.135
pkm2a pyruvate kinase, muscle, a 0.132
hk1 hexokinase 1 0.126
atp1b2a ATPase, Na+/K+ transporting, beta 2a polypeptide 0.113
sh3gl2 SH3-domain GRB2-like 2 0.092
apc adenomatosis polyposis coli 0.087
plcxd3 phosphatidylinositol-specific phospholipase C, X domain containing 3 0.061
actn2 actinin, alpha 2 0.057
nadl1.2 neural adhesion molecule L1.2 0.047
olfm2 olfactomedin 2 0.046
ptprk protein tyrosine phosphatase, receptor type, K 0.044
zgc:73142 zgc:73142 0.040
ppdpfa pancreatic progenitor cell differentiation and proliferation factor a 0.039
cx39.9 connexin 39.9 0.036
myo7aa myosin VIIAa 0.035
tpi1b triosephosphate isomerase 1b 0.035
actr1 ARP1 actin-related protein 1, centractin (yeast) 0.034
efna5a ephrin A5a 0.034
stra6 stimulated by retinoic acid gene 6 homolog (mouse) 0.032
ache acetylcholinesterase 0.031
zgc:152984 zgc:152984 0.030
ap2a1 adaptor-related protein complex 2, alpha 1 subunit 0.030
copeb core promoter element binding protein 0.030
rtn1a reticulon 1a 0.029
gpia glucose phosphate isomerase a 0.029
oprm1 opioid receptor, mu 1 0.028
zbtb10 zinc finger and BTB domain containing 10 0.026
pdcd4a programmed cell death 4a 0.026
nr2f6b nuclear receptor subfamily 2, group F, member 6b 0.026
scn12aa sodium channel, voltage gated, type XII, alpha a 0.026
atp2b1a ATPase, Ca++ transporting, plasma membrane 1a 0.026
xirp1 xin actin-binding repeat containing 1 0.025
zgc:136894 zgc:136894 0.024
wu:fc57f07 wu:fc57f07 0.024
vldlr very low density lipoprotein receptor 0.024
ndrg1 N-myc downstream regulated gene 1 0.024
hpca hippocalcin 0.024
cdipt CDP-diacylglycerol--inositol 3-phosphatidyltransferase (phosphatidylinositol synthase) 0.024
gipc2 GIPC PDZ domain containing family, member 2 0.023
ccbl1 cysteine conjugate-beta lyase; cytoplasmic (glutamine transaminase K, kyneurenine aminotransferase) 0.023
pcdh15a protocadherin 15a 0.023
mafl v-maf musculoaponeurotic fibrosarcoma (avian) oncogene family, protein L 0.023
igfbp3 insulin-like growth factor binding protein 3 0.023
ldha lactate dehydrogenase A4 0.023
wu:fb99e06 wu:fb99e06 0.023
ncs1a neuronal calcium sensor 1a 0.023
tspan7b tetraspanin 7b 0.023
pbxip1a pre-B-cell leukemia homeobox interacting protein 1a 0.022
rhoua ras homolog gene family, member Ua 0.022
calm2a calmodulin 2a (phosphorylase kinase, delta) 0.022
aldocb aldolase C, fructose-bisphosphate, b 0.022
pdcd6ip programmed cell death 6 interacting protein 0.022
gclc glutamate-cysteine ligase, catalytic subunit 0.022
got2b glutamic-oxaloacetic transaminase 2b, mitochondrial (aspartate aminotransferase 2) 0.021
clstn1 calsyntenin 1 0.021
ywhah tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide 0.021
atp1a1a.2 ATPase, Na+/K+ transporting, alpha 1a.2 polypeptide 0.020
ndrg3b N-myc downstream regulated family member 3b 0.020
hmgcs1 3-hydroxy-3-methylglutaryl-Coenzyme A synthase 1 (soluble) 0.020
msxa muscle segment homeobox A 0.020
mpp2b membrane protein, palmitoylated 2b (MAGUK p55 subfamily member 2b) 0.020
mybpc3 myosin binding protein C, cardiac 0.020
eml2 echinoderm microtubule associated protein like 2 0.020
zgc:85889 zgc:85889 0.020
zgc:92027 zgc:92027 0.020
oprd1a opioid receptor, delta 1a 0.020
nlgn4a neuroligin 4a 0.019
has3 hyaluronan synthase 3 0.019
ccbe1 collagen and calcium binding EGF domains 1 0.019
sept7a septin 7a 0.019
si:ch73-56f16.1 si:ch73-56f16.1 0.019
ndufa4 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4 0.018
drd3 dopamine receptor D3 0.018
wtip Wilms tumor 1 interacting protein 0.018
uchl1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) 0.018
atp1a1a.4 ATPase, Na+/K+ transporting, alpha 1a.4 polypeptide 0.018
cdh17 cadherin 17, LI cadherin (liver-intestine) 0.018
srpr signal recognition particle receptor (docking protein) 0.017
atp1a1 ATPase, Na+/K+ transporting, alpha 1 polypeptide 0.017
stmn2a stathmin-like 2a 0.017
atp6v1b2 ATPase, H+ transporting, lysosomal V1 subunit B2 0.017
wu:fb17b11 wu:fb17b11 0.017
ckbb creatine kinase, brain b 0.017
slc25a25a solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 25a 0.017
mpp5b membrane protein, palmitoylated 5b (MAGUK p55 subfamily member 5b) 0.017
plagl2 pleiomorphic adenoma gene-like 2 0.016
zgc:56429 zgc:56429 0.016
prkcd protein kinase C, delta 0.016
zgc:56005 zgc:56005 0.016
acsbg2 acyl-CoA synthetase bubblegum family member 2 0.016
gnrh2 gonadotropin-releasing hormone 2 0.015
phlda1 pleckstrin homology-like domain, family A, member 1 0.015
zgc:91860 zgc:91860 0.015
upb1 ureidopropionase, beta 0.015
zgc:112992 zgc:112992 0.015
slc17a6a solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 6a 0.015
tkt transketolase 0.015
Loading network...
Caenorhabditis elegans
Name Description Probability Func Analog Organism
Loading network...
Drosophila melanogaster
Name Description Probability Func Analog Organism
Loading network...
Homo sapiens
Name Description Probability Func Analog Organism
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide 1.000
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide 1.000
YWHAG tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide 0.999
NEDD4L neural precursor cell expressed, developmentally down-regulated 4-like 0.982
SCN5A sodium channel, voltage-gated, type V, alpha subunit 0.942
MPZL2 myelin protein zero-like 2 0.923
MPZL3 myelin protein zero-like 3 0.909
CAMK2A calcium/calmodulin-dependent protein kinase II alpha 0.838
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1 0.774
RNF11 ring finger protein 11 0.621
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) 0.618
DAG1 dystroglycan 1 (dystrophin-associated glycoprotein 1) 0.571
SNTG2 syntrophin, gamma 2 0.566
MAPK12 mitogen-activated protein kinase 12 0.491
YAP1 Yes-associated protein 1 0.445
KLHL3 kelch-like 3 (Drosophila) 0.424
GRIN2B glutamate receptor, ionotropic, N-methyl D-aspartate 2B 0.344
YWHAH tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide 0.305
DTNA dystrobrevin, alpha 0.304
UTRN utrophin 0.299
SMURF2 SMAD specific E3 ubiquitin protein ligase 2 0.264
GHR growth hormone receptor 0.259
CAMK2B calcium/calmodulin-dependent protein kinase II beta 0.251
SNTB2 syntrophin, beta 2 (dystrophin-associated protein A1, 59kDa, basic component 2) 0.224
WWP1 WW domain containing E3 ubiquitin protein ligase 1 0.221
ADORA2A adenosine A2a receptor 0.210
CLCN3 chloride channel 3 0.163
SYNM synemin, intermediate filament protein 0.144
FBXL15 F-box and leucine-rich repeat protein 15 0.142
ZFYVE9 zinc finger, FYVE domain containing 9 0.117
SLC6A3 solute carrier family 6 (neurotransmitter transporter, dopamine), member 3 0.116
PDZK1 PDZ domain containing 1 0.114
SCNN1B sodium channel, nonvoltage-gated 1, beta 0.105
SLC9A3R1 solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1 0.104
PPP1R9B protein phosphatase 1, regulatory (inhibitor) subunit 9B 0.094
WNK1 WNK lysine deficient protein kinase 1 0.086
TSC22D4 TSC22 domain family, member 4 0.080
ANKRD13A ankyrin repeat domain 13A 0.075
MARK2 MAP/microtubule affinity-regulating kinase 2 0.074
HMG20A high mobility group 20A 0.071
SLC9A3R2 solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 2 0.061
PTPN12 protein tyrosine phosphatase, non-receptor type 12 0.061
CDC25B cell division cycle 25 homolog B (S. pombe) 0.058
RAF1 v-raf-1 murine leukemia viral oncogene homolog 1 0.055
SMAD5 SMAD family member 5 0.054
PAG1 phosphoprotein associated with glycosphingolipid microdomains 1 0.054
RAPGEF2 Rap guanine nucleotide exchange factor (GEF) 2 0.046
AP2B1 adaptor-related protein complex 2, beta 1 subunit 0.045
SMAD1 SMAD family member 1 0.040
SLC9A1 solute carrier family 9 (sodium/hydrogen exchanger), member 1 0.039
DTNB dystrobrevin, beta 0.039
GLIS2 GLIS family zinc finger 2 0.037
TBC1D10A TBC1 domain family, member 10A 0.036
SMURF1 SMAD specific E3 ubiquitin protein ligase 1 0.034
CYLD cylindromatosis (turban tumor syndrome) 0.034
DGCR14 DiGeorge syndrome critical region gene 14 0.034
FRS2 fibroblast growth factor receptor substrate 2 0.032
NEDD4 neural precursor cell expressed, developmentally down-regulated 4 0.032
OXSR1 oxidative-stress responsive 1 0.031
CXXC5 CXXC finger protein 5 0.026
MMP23B matrix metallopeptidase 23B 0.026
ING1 inhibitor of growth family, member 1 0.025
MAGI3 membrane associated guanylate kinase, WW and PDZ domain containing 3 0.025
SFN stratifin 0.024
AP2M1 adaptor-related protein complex 2, mu 1 subunit 0.024
YWHAQ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide 0.023
SNTA1 syntrophin, alpha 1 (dystrophin-associated protein A1, 59kDa, acidic component) 0.022
DMD dystrophin 0.022
ITCH itchy E3 ubiquitin protein ligase homolog (mouse) 0.021
NDRG2 NDRG family member 2 0.020
GGA1 golgi-associated, gamma adaptin ear containing, ARF binding protein 1 0.019
WWP2 WW domain containing E3 ubiquitin protein ligase 2 0.018
EZR ezrin 0.018
SMAD7 SMAD family member 7 0.018
CPSF6 cleavage and polyadenylation specific factor 6, 68kDa 0.018
CAMKK1 calcium/calmodulin-dependent protein kinase kinase 1, alpha 0.018
KCNJ4 potassium inwardly-rectifying channel, subfamily J, member 4 0.017
DLG4 discs, large homolog 4 (Drosophila) 0.017
ADRB2 adrenergic, beta-2-, receptor, surface 0.017
KAT5 K(lysine) acetyltransferase 5 0.017
SPG20 spastic paraplegia 20 (Troyer syndrome) 0.017
GRIA4 glutamate receptor, ionotrophic, AMPA 4 0.016
SLC9A3 solute carrier family 9 (sodium/hydrogen exchanger), member 3 0.016
RAI1 retinoic acid induced 1 0.016
HRC histidine rich calcium binding protein 0.016
USP19 ubiquitin specific peptidase 19 0.016
PYGM phosphorylase, glycogen, muscle 0.016
KCNC1 potassium voltage-gated channel, Shaw-related subfamily, member 1 0.015
ARRDC3 arrestin domain containing 3 0.015
JPH2 junctophilin 2 0.015
HDAC4 histone deacetylase 4 0.015
ATP2B2 ATPase, Ca++ transporting, plasma membrane 2 0.015
OPTN optineurin 0.015
PPP2R1A protein phosphatase 2, regulatory subunit A, alpha 0.015
LDB3 LIM domain binding 3 0.014
NEDD9 neural precursor cell expressed, developmentally down-regulated 9 0.014
UBQLN2 ubiquilin 2 0.014
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide 0.014
CSNK1D casein kinase 1, delta 0.014
KCNB1 potassium voltage-gated channel, Shab-related subfamily, member 1 0.014
Loading network...
Mus musculus
Name Description Probability Func Analog Organism
Slc34a1 solute carrier family 34 (sodium phosphate), member 1 0.994
Dmd dystrophin, muscular dystrophy 0.775
Snta1 syntrophin, acidic 1 0.521
Nr3c1 nuclear receptor subfamily 3, group C, member 1 0.441
Sgca sarcoglycan, alpha (dystrophin-associated glycoprotein) 0.298
Col4a3 collagen, type IV, alpha 3 0.174
Timp4 tissue inhibitor of metalloproteinase 4 0.172
Ywhab tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide 0.165
Nos3 nitric oxide synthase 3, endothelial cell 0.149
Dag1 dystroglycan 1 0.149
Ache acetylcholinesterase 0.141
Dtna dystrobrevin alpha 0.096
Slc17a1 solute carrier family 17 (sodium phosphate), member 1 0.088
Mtap2 microtubule-associated protein 2 0.065
Lep leptin 0.053
Pygm muscle glycogen phosphorylase 0.049
Mapt microtubule-associated protein tau 0.044
Myl2 myosin, light polypeptide 2, regulatory, cardiac, slow 0.043
Atp1b2 ATPase, Na+/K+ transporting, beta 2 polypeptide 0.042
Vegfa vascular endothelial growth factor A 0.041
Bspry B-box and SPRY domain containing 0.036
Ehd3 EH-domain containing 3 0.032
Nt5e 5' nucleotidase, ecto 0.031
Cav3 caveolin 3 0.031
Phkg1 phosphorylase kinase gamma 1 0.030
Hrc histidine rich calcium binding protein 0.029
Limch1 LIM and calponin homology domains 1 0.027
Cd151 CD151 antigen 0.027
Rarres2 retinoic acid receptor responder (tazarotene induced) 2 0.024
Rnf112 ring finger protein 112 0.024
Sparcl1 SPARC-like 1 0.024
Ndrg2 N-myc downstream regulated gene 2 0.024
Fktn fukutin 0.024
Plin4 perilipin 4 0.024
Pdzd3 PDZ domain containing 3 0.023
Hspb8 heat shock protein 8 0.023
Ppargc1a peroxisome proliferative activated receptor, gamma, coactivator 1 alpha 0.023
Hhatl hedgehog acyltransferase-like 0.023
Dctpp1 dCTP pyrophosphatase 1 0.022
Atp1a2 ATPase, Na+/K+ transporting, alpha 2 polypeptide 0.021
Cdh13 cadherin 13 0.021
Wbp2 WW domain binding protein 2 0.020
Atp1a1 ATPase, Na+/K+ transporting, alpha 1 polypeptide 0.020
Lmx1b LIM homeobox transcription factor 1 beta 0.020
Slc2a4 solute carrier family 2 (facilitated glucose transporter), member 4 0.019
Vdr vitamin D receptor 0.019
Eef1a2 eukaryotic translation elongation factor 1 alpha 2 0.018
Prnp prion protein 0.018
Ppp1r1a protein phosphatase 1, regulatory (inhibitor) subunit 1A 0.017
Prdx6 peroxiredoxin 6 0.017
Pomc pro-opiomelanocortin-alpha 0.017
Igfbp6 insulin-like growth factor binding protein 6 0.017
Fndc5 fibronectin type III domain containing 5 0.017
Sct secretin 0.016
Fxyd1 FXYD domain-containing ion transport regulator 1 0.016
Cox8b cytochrome c oxidase, subunit VIIIb 0.016
Sh3gl2 SH3-domain GRB2-like 2 0.016
Prkg1 protein kinase, cGMP-dependent, type I 0.016
Nptx2 neuronal pentraxin 2 0.015
Hr hairless 0.015
Tspan7 tetraspanin 7 0.015
Dlg4 discs, large homolog 4 (Drosophila) 0.015
Lama2 laminin, alpha 2 0.014
Slc9a3r1 solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1 0.014
Art5 ADP-ribosyltransferase 5 0.014
Homer1 homer homolog 1 (Drosophila) 0.014
Rab25 RAB25, member RAS oncogene family 0.014
Vamp2 vesicle-associated membrane protein 2 0.013
Kcnh7 potassium voltage-gated channel, subfamily H (eag-related), member 7 0.013
Crim1 cysteine rich transmembrane BMP regulator 1 (chordin like) 0.013
Anpep alanyl (membrane) aminopeptidase 0.013
Actn2 actinin alpha 2 0.013
Cav1 caveolin 1, caveolae protein 0.013
Plau plasminogen activator, urokinase 0.013
Clic3 chloride intracellular channel 3 0.012
Fam131a family with sequence similarity 131, member A 0.012
S100a16 S100 calcium binding protein A16 0.012
Pdzk1 PDZ domain containing 1 0.012
Gja1 gap junction protein, alpha 1 0.012
Aqp1 aquaporin 1 0.012
Pacsin1 protein kinase C and casein kinase substrate in neurons 1 0.012
Apoc3 apolipoprotein C-III 0.012
Casr calcium-sensing receptor 0.012
Frs3 fibroblast growth factor receptor substrate 3 0.012
Tph2 tryptophan hydroxylase 2 0.012
Myh6 myosin, heavy polypeptide 6, cardiac muscle, alpha 0.011
Epas1 endothelial PAS domain protein 1 0.011
Rtn2 reticulon 2 (Z-band associated protein) 0.011
Plp1 proteolipid protein (myelin) 1 0.011
Sgcg sarcoglycan, gamma (dystrophin-associated glycoprotein) 0.011
Rgs5 regulator of G-protein signaling 5 0.011
Ap2m1 adaptor protein complex AP-2, mu1 0.011
Hrh1 histamine receptor H1 0.011
Slc27a1 solute carrier family 27 (fatty acid transporter), member 1 0.011
Atp2a1 ATPase, Ca++ transporting, cardiac muscle, fast twitch 1 0.011
Rapsn receptor-associated protein of the synapse 0.011
Epn1 epsin 1 0.011
Ptprb protein tyrosine phosphatase, receptor type, B 0.011
Kcnh2 potassium voltage-gated channel, subfamily H (eag-related), member 2 0.011
Fhod3 formin homology 2 domain containing 3 0.010
Loading network...
Rattus norvegicus
Name Description Probability Func Analog Organism
Loading network...
Saccharomyces cerevisiae
Name Description Probability Func Analog Organism