|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
181 |
1.000
|
Human Rat |
|
|
nerve development
|
GO:0021675 |
4 |
1.000
|
Zebrafish Mouse |
|
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
303 |
1.000
|
Human Rat |
|
|
cranial nerve development
|
GO:0021545 |
4 |
1.000
|
Zebrafish Mouse |
|
|
positive regulation of phosphatidylinositol 3 kinase activity
|
GO:0043552 |
12 |
1.000
|
Human |
|
|
tyrosine phosphorylation of stat protein
|
GO:0007260 |
33 |
1.000
|
Human |
|
|
regulation of lipid kinase activity
|
GO:0043550 |
19 |
1.000
|
Human |
|
|
positive regulation of lipid kinase activity
|
GO:0090218 |
13 |
1.000
|
Human |
|
|
cellular lipid metabolic process
|
GO:0044255 |
303 |
1.000
|
Human |
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
336 |
1.000
|
Human Rat |
|
|
protein autophosphorylation
|
GO:0046777 |
123 |
1.000
|
Human |
|
|
peptidyl tyrosine modification
|
GO:0018212 |
170 |
1.000
|
|
|
|
positive regulation of cell proliferation
|
GO:0008284 |
301 |
1.000
|
Human Fly |
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
1.000
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
314 |
1.000
|
|
|
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
170 |
1.000
|
|
|
|
positive regulation of protein tyrosine kinase activity
|
GO:0061098 |
24 |
1.000
|
|
|
|
regulation of cell migration
|
GO:0030334 |
289 |
1.000
|
Human |
|
|
positive regulation of transferase activity
|
GO:0051347 |
227 |
1.000
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
73 |
1.000
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
204 |
1.000
|
|
|
|
regulation of lipid metabolic process
|
GO:0019216 |
96 |
1.000
|
Human |
|
|
biological adhesion
|
GO:0022610 |
331 |
1.000
|
|
|
|
tyrosine phosphorylation of stat5 protein
|
GO:0042506 |
13 |
1.000
|
Human |
|
|
organ morphogenesis
|
GO:0009887 |
147 |
1.000
|
Rat Fly |
|
|
positive regulation of lipid metabolic process
|
GO:0045834 |
50 |
1.000
|
Human |
|
|
peripheral nervous system development
|
GO:0007422 |
2 |
1.000
|
Zebrafish Mouse Fly |
|
|
phospholipid metabolic process
|
GO:0006644 |
99 |
1.000
|
Human |
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
1.000
|
|
|
|
neural crest cell migration
|
GO:0001755 |
2 |
1.000
|
Zebrafish |
|
|
regulation of locomotion
|
GO:0040012 |
329 |
1.000
|
Human |
|
|
stem cell differentiation
|
GO:0048863 |
93 |
1.000
|
Zebrafish Fly |
|
|
epithelium development
|
GO:0060429 |
227 |
1.000
|
Fly |
|
|
phosphatidylinositol mediated signaling
|
GO:0048015 |
55 |
0.999
|
|
|
|
positive regulation of phosphorylation
|
GO:0042327 |
394 |
0.999
|
|
|
|
positive regulation of map kinase activity
|
GO:0043406 |
80 |
0.999
|
Human |
|
|
tissue morphogenesis
|
GO:0048729 |
96 |
0.999
|
Fly |
|
|
regulation of phosphatidylinositol 3 kinase activity
|
GO:0043551 |
14 |
0.999
|
Human |
|
|
positive regulation of cardiac muscle cell proliferation
|
GO:0060045 |
2 |
0.999
|
|
|
|
regulation of body fluid levels
|
GO:0050878 |
99 |
0.999
|
Human |
|
|
amine metabolic process
|
GO:0009308 |
44 |
0.999
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
78 |
0.999
|
|
|
|
regulation of cell adhesion
|
GO:0030155 |
166 |
0.999
|
|
|
|
regulation of peptidyl tyrosine phosphorylation
|
GO:0050730 |
108 |
0.999
|
|
|
|
cell development
|
GO:0048468 |
328 |
0.998
|
Zebrafish Rat Fly |
|
|
regulation of neuron differentiation
|
GO:0045664 |
70 |
0.998
|
|
|
|
leukocyte activation
|
GO:0045321 |
164 |
0.998
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
190 |
0.998
|
|
|
|
epithelial cell migration
|
GO:0010631 |
119 |
0.998
|
Fly |
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
0.998
|
|
|
|
regulation of epithelial cell migration
|
GO:0010632 |
93 |
0.998
|
|
|
|
activation of protein kinase activity
|
GO:0032147 |
90 |
0.998
|
|
|
|
muscle cell proliferation
|
GO:0033002 |
35 |
0.998
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
41 |
0.998
|
|
|
|
neuron differentiation
|
GO:0030182 |
138 |
0.998
|
Zebrafish Rat Fly |
|
|
positive regulation of leukocyte activation
|
GO:0002696 |
80 |
0.997
|
|
|
|
cell adhesion
|
GO:0007155 |
325 |
0.997
|
|
|
|
regulation of cell activation
|
GO:0050865 |
125 |
0.997
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.997
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.997
|
|
|
|
cell activation
|
GO:0001775 |
213 |
0.996
|
|
|
|
regulation of cellular component movement
|
GO:0051270 |
334 |
0.996
|
Human |
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.996
|
|
|
|
actin filament organization
|
GO:0007015 |
128 |
0.996
|
|
|
|
positive regulation of developmental process
|
GO:0051094 |
314 |
0.995
|
Worm |
|
|
generation of neurons
|
GO:0048699 |
152 |
0.995
|
Zebrafish Rat Fly |
|
|
ameboidal type cell migration
|
GO:0001667 |
135 |
0.995
|
Zebrafish Fly |
|
|
lipid metabolic process
|
GO:0006629 |
381 |
0.995
|
Human |
|
|
mitochondrial fragmentation involved in apoptotic process
|
GO:0043653 |
7 |
0.994
|
Human |
|
|
tyrosine phosphorylation of stat3 protein
|
GO:0042503 |
20 |
0.994
|
|
|
|
rho protein signal transduction
|
GO:0007266 |
26 |
0.994
|
|
|
|
activation of transmembrane receptor protein tyrosine kinase activity
|
GO:0007171 |
4 |
0.993
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
289 |
0.993
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
313 |
0.993
|
|
|
|
regulation of cell projection organization
|
GO:0031344 |
107 |
0.993
|
|
|
|
positive regulation of cell adhesion
|
GO:0045785 |
84 |
0.993
|
Human |
|
|
regulation of small gtpase mediated signal transduction
|
GO:0051056 |
156 |
0.993
|
|
|
|
inositol lipid mediated signaling
|
GO:0048017 |
55 |
0.993
|
|
|
|
tongue development
|
GO:0043586 |
1 |
0.993
|
Rat |
|
|
positive regulation of ras gtpase activity
|
GO:0032320 |
117 |
0.993
|
|
|
|
positive regulation of locomotion
|
GO:0040017 |
186 |
0.993
|
Human |
|
|
response to oxygen containing compound
|
GO:1901700 |
369 |
0.992
|
Human Rat Fly |
|
|
single organism cell adhesion
|
GO:0098602 |
179 |
0.992
|
Human Fly |
|
|
anatomical structure formation involved in morphogenesis
|
GO:0048646 |
284 |
0.992
|
Fly |
|
|
cell morphogenesis involved in differentiation
|
GO:0000904 |
144 |
0.992
|
Zebrafish Rat |
|
|
mammary gland involution
|
GO:0060056 |
1 |
0.991
|
Rat |
|
|
positive regulation of transport
|
GO:0051050 |
336 |
0.990
|
Human Rat |
|
|
cell morphogenesis
|
GO:0000902 |
296 |
0.990
|
Zebrafish Rat |
|
|
cellular divalent inorganic cation homeostasis
|
GO:0072503 |
128 |
0.990
|
|
|
|
positive regulation of peptidyl tyrosine phosphorylation
|
GO:0050731 |
85 |
0.989
|
|
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
239 |
0.988
|
|
|
|
cellular component morphogenesis
|
GO:0032989 |
314 |
0.987
|
Zebrafish Rat Fly |
|
|
male genitalia development
|
GO:0030539 |
1 |
0.987
|
Worm |
|
|
glycerolipid metabolic process
|
GO:0046486 |
107 |
0.987
|
Human |
|
|
actin filament based process
|
GO:0030029 |
224 |
0.987
|
|
|
|
regulation of protein tyrosine kinase activity
|
GO:0061097 |
36 |
0.986
|
|
|
|
tube development
|
GO:0035295 |
125 |
0.986
|
Fly |
|
|
extrinsic apoptotic signaling pathway in absence of ligand
|
GO:0097192 |
22 |
0.985
|
|
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.985
|
Fly |
|
|
positive regulation of phosphatidylinositol 3 kinase signaling
|
GO:0014068 |
28 |
0.985
|
|
|
|
regulation of cardiac muscle cell proliferation
|
GO:0060043 |
4 |
0.984
|
|
|
|
metal ion homeostasis
|
GO:0055065 |
169 |
0.984
|
|
|
|
neurological system process
|
GO:0050877 |
163 |
0.983
|
Zebrafish Fly |
|
|
cellular response to oxygen containing compound
|
GO:1901701 |
276 |
0.982
|
Human Rat |
|
|
erk1 and erk2 cascade
|
GO:0070371 |
104 |
0.982
|
Human |
|
|
jak stat cascade
|
GO:0007259 |
46 |
0.981
|
Human |
|
|
positive regulation of neuron differentiation
|
GO:0045666 |
40 |
0.980
|
|
|
|
innate immune response
|
GO:0045087 |
178 |
0.980
|
|
|
|
immune response regulating signaling pathway
|
GO:0002764 |
97 |
0.979
|
|
|
|
positive regulation of endothelial cell migration
|
GO:0010595 |
39 |
0.979
|
|
|
|
regulation of neuron projection development
|
GO:0010975 |
57 |
0.979
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
268 |
0.979
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
413 |
0.979
|
|
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.979
|
Human Mouse Fly |
|
|
regulation of mapk cascade
|
GO:0043408 |
262 |
0.978
|
Human |
|
|
immune response regulating cell surface receptor signaling pathway
|
GO:0002768 |
51 |
0.978
|
|
|
|
phosphatidylinositol 3 kinase signaling
|
GO:0014065 |
48 |
0.978
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
6 |
0.976
|
|
|
|
regulation of blood coagulation
|
GO:0030193 |
42 |
0.975
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
92 |
0.975
|
|
|
|
regulation of secretion
|
GO:0051046 |
194 |
0.975
|
|
|
|
activation of mapk activity
|
GO:0000187 |
45 |
0.975
|
|
|
|
regulation of vesicle mediated transport
|
GO:0060627 |
130 |
0.973
|
|
|
|
immune system development
|
GO:0002520 |
195 |
0.973
|
|
|
|
negative regulation of immature t cell proliferation
|
GO:0033087 |
1 |
0.971
|
|
|
|
gtp catabolic process
|
GO:0006184 |
237 |
0.971
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
228 |
0.969
|
Human |
|
|
immune response activating cell surface receptor signaling pathway
|
GO:0002429 |
45 |
0.969
|
|
|
|
regulation of protein kinase b signaling
|
GO:0051896 |
61 |
0.968
|
Human |
|
|
lymphocyte activation
|
GO:0046649 |
133 |
0.968
|
|
|
|
transcription from rna polymerase iii promoter
|
GO:0006383 |
19 |
0.968
|
Human |
|
|
regulation of nucleotide catabolic process
|
GO:0030811 |
205 |
0.967
|
|
|
|
cation homeostasis
|
GO:0055080 |
189 |
0.966
|
|
|
|
positive regulation of neuron projection development
|
GO:0010976 |
34 |
0.966
|
|
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
155 |
0.966
|
|
|
|
negative regulation of programmed cell death
|
GO:0043069 |
321 |
0.965
|
Human Mouse Fly |
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
392 |
0.964
|
|
|
|
digestive tract development
|
GO:0048565 |
75 |
0.963
|
Fly |
|
|
antigen receptor mediated signaling pathway
|
GO:0050851 |
38 |
0.962
|
|
|
|
regulation of immune response
|
GO:0050776 |
201 |
0.961
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
391 |
0.958
|
Human |
|
|
regulation of lymphocyte activation
|
GO:0051249 |
103 |
0.957
|
|
|
|
regulation of cyclin dependent protein serine threonine kinase activity involved in g1 s transition of mitotic cell cycle
|
GO:0031657 |
9 |
0.957
|
Human |
|
|
tissue migration
|
GO:0090130 |
119 |
0.956
|
Fly |
|
|
neuron projection development
|
GO:0031175 |
106 |
0.956
|
Zebrafish Rat |
|
|
hematopoietic or lymphoid organ development
|
GO:0048534 |
186 |
0.955
|
|
|
|
hindbrain development
|
GO:0030902 |
3 |
0.954
|
|
|
|
positive regulation of tyrosine phosphorylation of stat5 protein
|
GO:0042523 |
11 |
0.952
|
Human |
|
|
forebrain generation of neurons
|
GO:0021872 |
3 |
0.952
|
|
|
|
regulation of cell motility
|
GO:2000145 |
299 |
0.951
|
Human |
|
|
negative regulation of apoptotic signaling pathway
|
GO:2001234 |
97 |
0.951
|
Fly |
|
|
positive regulation of immune response
|
GO:0050778 |
159 |
0.951
|
|
|
|
positive regulation of cell activation
|
GO:0050867 |
81 |
0.950
|
|
|
|
regulation of secretion by cell
|
GO:1903530 |
177 |
0.948
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
391 |
0.945
|
|
|
|
immune effector process
|
GO:0002252 |
159 |
0.944
|
|
|
|
positive regulation of rac gtpase activity
|
GO:0032855 |
31 |
0.944
|
|
|
|
positive regulation of erk1 and erk2 cascade
|
GO:0070374 |
75 |
0.943
|
Human |
|
|
regulation of leukocyte proliferation
|
GO:0070663 |
67 |
0.943
|
|
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
119 |
0.943
|
Human |
|
|
regulation of response to wounding
|
GO:1903034 |
101 |
0.942
|
Fly |
|
|
stem cell development
|
GO:0048864 |
69 |
0.941
|
Zebrafish Fly |
|
|
gtp metabolic process
|
GO:0046039 |
239 |
0.941
|
|
|
|
behavior
|
GO:0007610 |
112 |
0.941
|
Fly |
|
|
response to peptide
|
GO:1901652 |
65 |
0.940
|
Rat |
|
|
immune response activating signal transduction
|
GO:0002757 |
90 |
0.939
|
|
|
|
cell projection assembly
|
GO:0030031 |
126 |
0.938
|
Fly |
|
|
response to organonitrogen compound
|
GO:0010243 |
156 |
0.937
|
Rat |
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
284 |
0.933
|
|
|
|
regulation of cell development
|
GO:0060284 |
161 |
0.932
|
Fly |
|
|
chemotaxis
|
GO:0006935 |
157 |
0.932
|
|
|
|
positive regulation of neurogenesis
|
GO:0050769 |
49 |
0.931
|
|
|
|
mesenchymal cell differentiation
|
GO:0048762 |
52 |
0.930
|
Zebrafish |
|
|
activation of immune response
|
GO:0002253 |
114 |
0.930
|
|
|
|
response to growth factor
|
GO:0070848 |
205 |
0.927
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
232 |
0.925
|
|
|
|
growth
|
GO:0040007 |
202 |
0.925
|
Human Zebrafish |
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
7 |
0.923
|
|
|
|
neurogenesis
|
GO:0022008 |
169 |
0.923
|
Zebrafish Mouse Rat Fly |
|
|
actin cytoskeleton organization
|
GO:0030036 |
207 |
0.923
|
|
|
|
regulation of cell morphogenesis
|
GO:0022604 |
153 |
0.922
|
|
|
|
male sex differentiation
|
GO:0046661 |
25 |
0.921
|
Worm |
|
|
regulation of map kinase activity
|
GO:0043405 |
108 |
0.921
|
Human |
|
|
b cell receptor signaling pathway
|
GO:0050853 |
18 |
0.919
|
|
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
0.918
|
Human Mouse Fly |
|
|
signal transduction by phosphorylation
|
GO:0023014 |
297 |
0.917
|
Human |
|
|
regulation of rho protein signal transduction
|
GO:0035023 |
79 |
0.917
|
|
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
211 |
0.916
|
|
|
|
neural crest cell development
|
GO:0014032 |
3 |
0.915
|
Zebrafish |
|
|
positive regulation of cyclin dependent protein serine threonine kinase activity involved in g1 s transition of mitotic cell cycle
|
GO:0031659 |
8 |
0.914
|
Human |
|
|
regulation of t cell activation
|
GO:0050863 |
77 |
0.914
|
|
|
|
trabecula morphogenesis
|
GO:0061383 |
2 |
0.914
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
326 |
0.914
|
Human Fly |
|
|
cell projection organization
|
GO:0030030 |
252 |
0.911
|
Zebrafish Rat Fly |
|
|
positive regulation of epithelial cell proliferation
|
GO:0050679 |
65 |
0.911
|
Human |
|
|
tissue regeneration
|
GO:0042246 |
3 |
0.910
|
Zebrafish |
|
|
neural crest cell differentiation
|
GO:0014033 |
5 |
0.909
|
Zebrafish |
|
|
positive regulation of purine nucleotide metabolic process
|
GO:1900544 |
227 |
0.909
|
|
|
|
negative regulation of axon extension
|
GO:0030517 |
2 |
0.908
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
175 |
0.907
|
Fly |
|
|
secretion
|
GO:0046903 |
254 |
0.906
|
|
|
|
cell cell signaling
|
GO:0007267 |
155 |
0.906
|
|
|
|
cardiac muscle cell proliferation
|
GO:0060038 |
6 |
0.905
|
|
|
|
regulation of wound healing
|
GO:0061041 |
56 |
0.905
|
Fly |
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
412 |
0.903
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
331 |
0.900
|
|
|
|
neuronal action potential
|
GO:0019228 |
9 |
0.896
|
Zebrafish |
|
|
negative regulation of developmental process
|
GO:0051093 |
247 |
0.896
|
Fly |
|
|
cellular response to hormone stimulus
|
GO:0032870 |
125 |
0.895
|
Human Rat |
|
|
regulation of nervous system development
|
GO:0051960 |
88 |
0.895
|
|
|
|
mesenchyme development
|
GO:0060485 |
59 |
0.892
|
Zebrafish Mouse |
|
|
regulation of actin cytoskeleton organization
|
GO:0032956 |
116 |
0.891
|
|
|
|
positive regulation of lymphocyte proliferation
|
GO:0050671 |
46 |
0.891
|
|
|
|
positive regulation of cellular component movement
|
GO:0051272 |
181 |
0.891
|
Human |
|
|
phosphatidylinositol metabolic process
|
GO:0046488 |
53 |
0.891
|
Human |
|
|
associative learning
|
GO:0008306 |
1 |
0.891
|
Fly |
|
|
positive regulation of cyclin dependent protein serine threonine kinase activity
|
GO:0045737 |
15 |
0.888
|
Human |
|
|
regulation of neurogenesis
|
GO:0050767 |
82 |
0.887
|
|
|
|
establishment or maintenance of apical basal cell polarity
|
GO:0035088 |
2 |
0.885
|
Fly |
|
|
regulation of leukocyte activation
|
GO:0002694 |
115 |
0.883
|
|
|
|
cytokine mediated signaling pathway
|
GO:0019221 |
109 |
0.882
|
|
|
|
regulation of tyrosine phosphorylation of stat5 protein
|
GO:0042522 |
12 |
0.882
|
Human |
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
119 |
0.880
|
|
|
|
glycerophospholipid metabolic process
|
GO:0006650 |
84 |
0.878
|
Human |
|
|
regulation of ras gtpase activity
|
GO:0032318 |
128 |
0.875
|
|
|
|
single organismal cell cell adhesion
|
GO:0016337 |
148 |
0.875
|
Human Fly |
|
|
regulation of reactive oxygen species metabolic process
|
GO:2000377 |
41 |
0.875
|
|
|
|
negative regulation of cell differentiation
|
GO:0045596 |
171 |
0.874
|
Fly |
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
267 |
0.874
|
|
|
|
response to wounding
|
GO:0009611 |
168 |
0.870
|
Human Zebrafish Rat Fly |
|
|
divalent inorganic cation homeostasis
|
GO:0072507 |
136 |
0.869
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
412 |
0.867
|
|
|
|
epithelial cell differentiation
|
GO:0030855 |
141 |
0.867
|
Fly |
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
264 |
0.865
|
|
|
|
circulatory system development
|
GO:0072359 |
262 |
0.863
|
Mouse |
|
|
immature t cell proliferation
|
GO:0033079 |
1 |
0.861
|
|
|
|
peptidyl tyrosine autophosphorylation
|
GO:0038083 |
5 |
0.859
|
|
|
|
regulation of cardiac muscle tissue growth
|
GO:0055021 |
4 |
0.858
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
195 |
0.857
|
Human |
|
|
protein kinase b signaling
|
GO:0043491 |
69 |
0.856
|
Human |
|
|
response to uv a
|
GO:0070141 |
6 |
0.856
|
Human |
|
|
negative regulation of immature t cell proliferation in thymus
|
GO:0033088 |
1 |
0.855
|
|
|
|
regulation of erk1 and erk2 cascade
|
GO:0070372 |
99 |
0.851
|
Human |
|
|
photoreceptor cell differentiation
|
GO:0046530 |
2 |
0.851
|
Fly |
|
|
schwann cell development
|
GO:0014044 |
1 |
0.849
|
Zebrafish |
|
|
positive regulation of jak stat cascade
|
GO:0046427 |
35 |
0.843
|
Human |
|
|
positive regulation of cellular component organization
|
GO:0051130 |
376 |
0.842
|
|
|
|
positive regulation of leukocyte proliferation
|
GO:0070665 |
48 |
0.842
|
|
|
|
regulation of extrinsic apoptotic signaling pathway in absence of ligand
|
GO:2001239 |
20 |
0.839
|
|
|
|
cellular response to nitrogen compound
|
GO:1901699 |
144 |
0.836
|
Rat |
|
|
signal transduction in absence of ligand
|
GO:0038034 |
22 |
0.829
|
|
|
|
positive regulation of rho gtpase activity
|
GO:0032321 |
56 |
0.828
|
|
|
|
positive regulation of cytokine production
|
GO:0001819 |
167 |
0.827
|
|
|
|
glial cell development
|
GO:0021782 |
7 |
0.825
|
Zebrafish |
|
|
organophosphate catabolic process
|
GO:0046434 |
430 |
0.824
|
|
|
|
positive regulation of immune system process
|
GO:0002684 |
283 |
0.821
|
|
|
|
negative regulation of peptidyl tyrosine phosphorylation
|
GO:0050732 |
20 |
0.819
|
|
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
394 |
0.811
|
|
|
|
system process
|
GO:0003008 |
349 |
0.808
|
Zebrafish Fly |
|
|
regulation of phospholipase c activity
|
GO:1900274 |
14 |
0.806
|
|
|
|
regulation of rho gtpase activity
|
GO:0032319 |
66 |
0.806
|
|
|
|
positive regulation of t cell activation
|
GO:0050870 |
54 |
0.799
|
|
|
|
regulation of cardiac muscle tissue development
|
GO:0055024 |
13 |
0.797
|
|
|
|
regulation of gtpase activity
|
GO:0043087 |
180 |
0.795
|
|
|
|
positive regulation of heart growth
|
GO:0060421 |
2 |
0.778
|
|
|
|
compound eye development
|
GO:0048749 |
1 |
0.776
|
Fly |
|
|
regulation of lymphocyte proliferation
|
GO:0050670 |
64 |
0.769
|
|
|
|
coagulation
|
GO:0050817 |
78 |
0.768
|
|
|
|
motor neuron axon guidance
|
GO:0008045 |
2 |
0.767
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
179 |
0.767
|
Human |
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
412 |
0.765
|
|
|
|
nervous system development
|
GO:0007399 |
293 |
0.764
|
Zebrafish Mouse Rat Fly |
|
|
oogenesis
|
GO:0048477 |
2 |
0.761
|
Fly |
|
|
purine nucleoside catabolic process
|
GO:0006152 |
398 |
0.760
|
|
|
|
glycerolipid biosynthetic process
|
GO:0045017 |
51 |
0.756
|
|
|
|
positive regulation of nervous system development
|
GO:0051962 |
54 |
0.755
|
|
|
|
positive regulation of mononuclear cell proliferation
|
GO:0032946 |
47 |
0.744
|
|
|
|
protein catabolic process
|
GO:0030163 |
325 |
0.741
|
Human |
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
422 |
0.738
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
183 |
0.735
|
|
|
|
behavioral response to ethanol
|
GO:0048149 |
2 |
0.735
|
Fly |
|
|
positive regulation of gtpase activity
|
GO:0043547 |
166 |
0.730
|
|
|
|
regulation of phosphatidylinositol 3 kinase signaling
|
GO:0014066 |
35 |
0.729
|
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
406 |
0.726
|
|
|
|
positive regulation of angiogenesis
|
GO:0045766 |
51 |
0.725
|
|
|
|
regulation of translation
|
GO:0006417 |
89 |
0.725
|
Human |
|
|
positive regulation of intracellular protein transport
|
GO:0090316 |
76 |
0.722
|
Human |
|
|
positive regulation of interferon gamma mediated signaling pathway
|
GO:0060335 |
2 |
0.721
|
|
|
|
taxis
|
GO:0042330 |
157 |
0.717
|
|
|
|
interferon gamma production
|
GO:0032609 |
39 |
0.717
|
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
180 |
0.717
|
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
405 |
0.712
|
|
|
|
morphogenesis of embryonic epithelium
|
GO:0016331 |
4 |
0.709
|
Fly |
|
|
cdc42 protein signal transduction
|
GO:0032488 |
4 |
0.706
|
|
|
|
integrin mediated signaling pathway
|
GO:0007229 |
32 |
0.700
|
|
|
|
lipid modification
|
GO:0030258 |
84 |
0.699
|
Human |
|
|
mononuclear cell proliferation
|
GO:0032943 |
71 |
0.690
|
|
|
|
regulation of gtp catabolic process
|
GO:0033124 |
180 |
0.688
|
|
|
|
cerebellum development
|
GO:0021549 |
2 |
0.688
|
|
|
|
positive regulation of protein transport
|
GO:0051222 |
135 |
0.688
|
Human |
|
|
cell cycle phase transition
|
GO:0044770 |
173 |
0.686
|
Human Fly |
|
|
stat protein import into nucleus
|
GO:0007262 |
2 |
0.682
|
Human |
|
|
cell projection morphogenesis
|
GO:0048858 |
129 |
0.672
|
Rat |
|
|
central nervous system development
|
GO:0007417 |
123 |
0.669
|
|
|
|
astrocyte differentiation
|
GO:0048708 |
4 |
0.669
|
|
|
|
negative regulation of transport
|
GO:0051051 |
176 |
0.669
|
|
|
|
glial cell migration
|
GO:0008347 |
4 |
0.668
|
Zebrafish |
|
|
autonomic nervous system development
|
GO:0048483 |
1 |
0.666
|
|
|
|
response to abiotic stimulus
|
GO:0009628 |
336 |
0.663
|
Human |
|
|
cytoplasmic transport
|
GO:0016482 |
379 |
0.662
|
Human |
|
|
regulation of cell cell adhesion
|
GO:0022407 |
57 |
0.660
|
|
|
|
leukocyte differentiation
|
GO:0002521 |
98 |
0.660
|
|
|
|
cellular cation homeostasis
|
GO:0030003 |
163 |
0.659
|
|
|
|
striated muscle cell proliferation
|
GO:0014855 |
7 |
0.659
|
|
|
|
regulation of extrinsic apoptotic signaling pathway
|
GO:2001236 |
85 |
0.657
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
405 |
0.656
|
|
|
|
blood coagulation
|
GO:0007596 |
76 |
0.656
|
|
|
|
t cell activation
|
GO:0042110 |
99 |
0.656
|
|
|
|
regulation of actin filament based process
|
GO:0032970 |
141 |
0.654
|
|
|
|
positive regulation of lymphocyte activation
|
GO:0051251 |
73 |
0.653
|
|
|
|
schwann cell differentiation
|
GO:0014037 |
1 |
0.652
|
Zebrafish Mouse |
|
|
single organism reproductive process
|
GO:0044702 |
98 |
0.652
|
Worm Fly |
|
|
positive regulation of cytoplasmic transport
|
GO:1903651 |
82 |
0.650
|
Human |
|
|
gland development
|
GO:0048732 |
48 |
0.650
|
Human Rat Fly |
|
|
positive regulation of catabolic process
|
GO:0009896 |
310 |
0.649
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
391 |
0.646
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
140 |
0.643
|
|
|
|
reactive nitrogen species metabolic process
|
GO:2001057 |
3 |
0.642
|
|
|
|
negative regulation of extrinsic apoptotic signaling pathway
|
GO:2001237 |
52 |
0.641
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
263 |
0.635
|
|
|
|
cell morphogenesis involved in neuron differentiation
|
GO:0048667 |
44 |
0.630
|
Rat |
|
|
positive regulation of cell differentiation
|
GO:0045597 |
211 |
0.627
|
|
|
|
exocytosis
|
GO:0006887 |
71 |
0.626
|
|
|
|
positive regulation of tyrosine phosphorylation of stat protein
|
GO:0042531 |
28 |
0.626
|
Human |
|
|
positive regulation of gtp catabolic process
|
GO:0033126 |
166 |
0.623
|
|
|
|
positive regulation of nucleoside metabolic process
|
GO:0045979 |
186 |
0.619
|
|
|
|
regulation of cyclin dependent protein serine threonine kinase activity
|
GO:0000079 |
36 |
0.616
|
Human |
|
|
regeneration
|
GO:0031099 |
4 |
0.615
|
Zebrafish |
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
269 |
0.614
|
|
|
|
phosphatidylinositol phosphorylation
|
GO:0046854 |
24 |
0.613
|
Human |
|
|
early endosome to late endosome transport
|
GO:0045022 |
21 |
0.612
|
|
|
|
hemopoiesis
|
GO:0030097 |
180 |
0.612
|
|
|
|
muscle organ development
|
GO:0007517 |
56 |
0.610
|
Rat |
|
|
positive regulation of mapk cascade
|
GO:0043410 |
190 |
0.607
|
Human |
|
|
regulation of membrane potential
|
GO:0042391 |
95 |
0.605
|
Zebrafish |
|
|
positive regulation of apoptotic signaling pathway
|
GO:2001235 |
70 |
0.602
|
|
|
|
regulation of transcription from rna polymerase iii promoter
|
GO:0006359 |
13 |
0.602
|
Human |
|
|
endothelial cell migration
|
GO:0043542 |
86 |
0.601
|
|
|
|
negative regulation of cell adhesion
|
GO:0007162 |
64 |
0.594
|
|
|
|
female gamete generation
|
GO:0007292 |
2 |
0.588
|
Worm Fly |
|
|
nucleoside catabolic process
|
GO:0009164 |
408 |
0.588
|
|
|
|
regulation of defense response
|
GO:0031347 |
154 |
0.588
|
|
|
|
regulation of interferon gamma production
|
GO:0032649 |
36 |
0.586
|
|
|
|
regulation of cell growth
|
GO:0001558 |
135 |
0.585
|
Human |
|
|
axon development
|
GO:0061564 |
34 |
0.579
|
Zebrafish Rat |
|
|
cellular response to lipid
|
GO:0071396 |
127 |
0.578
|
Human |
|
|
negative regulation of axonogenesis
|
GO:0050771 |
4 |
0.576
|
|
|
|
action potential
|
GO:0001508 |
34 |
0.576
|
Zebrafish |
|
|
oocyte differentiation
|
GO:0009994 |
2 |
0.575
|
Fly |
|
|
regulation of cytokine mediated signaling pathway
|
GO:0001959 |
41 |
0.575
|
|
|
|
jnk cascade
|
GO:0007254 |
80 |
0.569
|
|
|
|
regulation of mononuclear cell proliferation
|
GO:0032944 |
65 |
0.567
|
|
|
|
regulation of protein secretion
|
GO:0050708 |
86 |
0.563
|
|
|
|
mesenchymal cell development
|
GO:0014031 |
50 |
0.563
|
Zebrafish |
|
|
positive regulation of dna repair
|
GO:0045739 |
25 |
0.560
|
Human |
|
|
positive regulation of transcription from rna polymerase iii promoter
|
GO:0045945 |
10 |
0.552
|
Human |
|
|
regulation of notch signaling pathway
|
GO:0008593 |
18 |
0.552
|
|
|
|
response to drug
|
GO:0042493 |
81 |
0.549
|
Rat |
|
|
regulation of cell cycle
|
GO:0051726 |
393 |
0.547
|
Human Fly |
|
|
nucleotide catabolic process
|
GO:0009166 |
408 |
0.544
|
|
|
|
regulation of lipase activity
|
GO:0060191 |
37 |
0.543
|
|
|
|
cardiovascular system development
|
GO:0072358 |
262 |
0.539
|
Mouse |
|
|
intrinsic apoptotic signaling pathway
|
GO:0097193 |
127 |
0.536
|
|
|
|
positive regulation of secretion
|
GO:0051047 |
116 |
0.535
|
|
|
|
neuron development
|
GO:0048666 |
113 |
0.535
|
Zebrafish Rat |
|
|
positive regulation of nucleotide catabolic process
|
GO:0030813 |
185 |
0.530
|
|
|
|
cellular homeostasis
|
GO:0019725 |
196 |
0.530
|
|
|
|
phenol containing compound metabolic process
|
GO:0018958 |
12 |
0.528
|
|
|
|
guanosine containing compound metabolic process
|
GO:1901068 |
244 |
0.528
|
|
|
|
epithelium migration
|
GO:0090132 |
119 |
0.527
|
Fly |
|
|
cell chemotaxis
|
GO:0060326 |
112 |
0.526
|
|
|
|
positive regulation of cell motility
|
GO:2000147 |
177 |
0.524
|
Human |
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
411 |
0.521
|
|
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
181 |
0.516
|
|
|
|
regulation of purine nucleotide catabolic process
|
GO:0033121 |
205 |
0.514
|
|
|
|
cellular ion homeostasis
|
GO:0006873 |
168 |
0.512
|
|
|
|
regulation of mast cell degranulation
|
GO:0043304 |
3 |
0.512
|
|
|
|
immune response
|
GO:0006955 |
307 |
0.509
|
|
|
|
lipid biosynthetic process
|
GO:0008610 |
177 |
0.503
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
379 |
0.500
|
Human |
|
|
negative regulation of cell migration
|
GO:0030336 |
102 |
0.499
|
|
|
|
positive regulation of cell migration
|
GO:0030335 |
172 |
0.499
|
Human |
|
|
oligodendrocyte differentiation
|
GO:0048709 |
7 |
0.498
|
|
|
|
b cell activation
|
GO:0042113 |
33 |
0.498
|
|
|
|
regulation of tyrosine phosphorylation of stat protein
|
GO:0042509 |
30 |
0.497
|
Human |
|
|
positive regulation of response to interferon gamma
|
GO:0060332 |
2 |
0.495
|
|
|
|
regulation of hormone levels
|
GO:0010817 |
125 |
0.492
|
|
|
|
vasculature development
|
GO:0001944 |
181 |
0.489
|
|
|
|
regulation of heart growth
|
GO:0060420 |
4 |
0.486
|
|
|
|
metencephalon development
|
GO:0022037 |
2 |
0.485
|
|
|
|
sprouting angiogenesis
|
GO:0002040 |
29 |
0.482
|
|
|
|
cerebral cortex cell migration
|
GO:0021795 |
3 |
0.478
|
|
|
|
cellular response to acid chemical
|
GO:0071229 |
44 |
0.474
|
|
|
|
secretion by cell
|
GO:0032940 |
226 |
0.474
|
|
|
|
negative regulation of leukocyte differentiation
|
GO:1902106 |
24 |
0.470
|
|
|
|
positive regulation of muscle cell differentiation
|
GO:0051149 |
15 |
0.459
|
|
|
|
t cell differentiation
|
GO:0030217 |
29 |
0.458
|
|
|
|
positive regulation of purine nucleotide catabolic process
|
GO:0033123 |
185 |
0.456
|
|
|
|
positive regulation of jnk cascade
|
GO:0046330 |
52 |
0.455
|
|
|
|
wound healing
|
GO:0042060 |
115 |
0.455
|
Human Zebrafish Fly |
|
|
defense response
|
GO:0006952 |
315 |
0.448
|
|
|
|
regulation of cell cycle g1 s phase transition
|
GO:1902806 |
42 |
0.445
|
Fly |
|
|
lymphocyte differentiation
|
GO:0030098 |
35 |
0.441
|
|
|
|
positive regulation of protein import into nucleus
|
GO:0042307 |
46 |
0.439
|
Human |
|
|
positive regulation of epithelial cell migration
|
GO:0010634 |
55 |
0.438
|
|
|
|
regulation of hemostasis
|
GO:1900046 |
42 |
0.438
|
|
|
|
regulation of jnk cascade
|
GO:0046328 |
73 |
0.435
|
|
|
|
regulation of organ growth
|
GO:0046620 |
7 |
0.434
|
|
|
|
positive regulation of protein localization to nucleus
|
GO:1900182 |
48 |
0.434
|
Human |
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
404 |
0.429
|
|
|
|
non canonical wnt signaling pathway
|
GO:0035567 |
14 |
0.424
|
|
|
|
mitochondrion organization
|
GO:0007005 |
156 |
0.424
|
Human |
|
|
positive regulation of small gtpase mediated signal transduction
|
GO:0051057 |
12 |
0.424
|
|
|
|
regulation of response to dna damage stimulus
|
GO:2001020 |
94 |
0.421
|
Human |
|
|
negative regulation of lymphocyte differentiation
|
GO:0045620 |
7 |
0.420
|
|
|
|
mitochondrial fission
|
GO:0000266 |
14 |
0.415
|
Human |
|
|
positive regulation of apoptotic process
|
GO:0043065 |
246 |
0.414
|
|
|
|
regulation of myeloid leukocyte mediated immunity
|
GO:0002886 |
4 |
0.412
|
|
|
|
cardiac muscle tissue development
|
GO:0048738 |
39 |
0.411
|
|
|
|
striated muscle cell differentiation
|
GO:0051146 |
43 |
0.410
|
|
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
149 |
0.408
|
Human |
|
|
mapk cascade
|
GO:0000165 |
288 |
0.407
|
Human |
|
|
response to retinoic acid
|
GO:0032526 |
33 |
0.403
|
|
|
|
extracellular matrix organization
|
GO:0030198 |
41 |
0.401
|
|
|
|
lipid phosphorylation
|
GO:0046834 |
31 |
0.400
|
Human |
|
|
positive regulation of cytokine mediated signaling pathway
|
GO:0001961 |
12 |
0.400
|
|
|
|
response to transforming growth factor beta
|
GO:0071559 |
94 |
0.399
|
|
|
|
regulation of microtubule based process
|
GO:0032886 |
74 |
0.396
|
Human |
|
|
establishment of protein localization to organelle
|
GO:0072594 |
172 |
0.392
|
Human |
|
|
lamellipodium organization
|
GO:0097581 |
30 |
0.392
|
|
|
|
regulation of actin cytoskeleton reorganization
|
GO:2000249 |
12 |
0.389
|
|
|
|
single organism cellular localization
|
GO:1902580 |
332 |
0.387
|
Human |
|
|
negative regulation of catabolic process
|
GO:0009895 |
104 |
0.385
|
Human |
|
|
response to nitrogen compound
|
GO:1901698 |
184 |
0.384
|
Rat |
|
|
lamellipodium assembly
|
GO:0030032 |
26 |
0.377
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
125 |
0.375
|
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
411 |
0.374
|
|
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
317 |
0.374
|
Fly |
|
|
immature t cell proliferation in thymus
|
GO:0033080 |
1 |
0.371
|
|
|
|
glycerophospholipid biosynthetic process
|
GO:0046474 |
40 |
0.369
|
|
|
|
translation
|
GO:0006412 |
132 |
0.368
|
Human |
|
|
activation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0006919 |
49 |
0.365
|
|
|
|
stress activated mapk cascade
|
GO:0051403 |
93 |
0.364
|
|
|
|
negative regulation of t cell differentiation in thymus
|
GO:0033085 |
2 |
0.363
|
|
|
|
regulation of protein localization
|
GO:0032880 |
296 |
0.363
|
Human |
|
|
positive regulation of protein kinase b signaling
|
GO:0051897 |
42 |
0.359
|
Human |
|
|
leukocyte proliferation
|
GO:0070661 |
74 |
0.359
|
|
|
|
neuron projection guidance
|
GO:0097485 |
12 |
0.355
|
|
|
|
cerebral cortex radially oriented cell migration
|
GO:0021799 |
1 |
0.355
|
|
|
|
regulation of endocytosis
|
GO:0030100 |
72 |
0.354
|
|
|
|
cellular response to growth hormone stimulus
|
GO:0071378 |
10 |
0.353
|
|
|
|
single organism behavior
|
GO:0044708 |
28 |
0.350
|
Fly |
|
|
digestive tract morphogenesis
|
GO:0048546 |
56 |
0.345
|
Fly |
|
|
chemical homeostasis
|
GO:0048878 |
306 |
0.344
|
|
|
|
regulation of epithelial cell proliferation
|
GO:0050678 |
113 |
0.343
|
Human |
|
|
morphogenesis of an epithelium
|
GO:0002009 |
60 |
0.341
|
Fly |
|
|
lactation
|
GO:0007595 |
3 |
0.341
|
Human |
|
|
positive regulation of proteolysis
|
GO:0045862 |
142 |
0.340
|
|
|
|
axonogenesis
|
GO:0007409 |
31 |
0.339
|
Rat |
|
|
positive regulation of wound healing
|
GO:0090303 |
20 |
0.336
|
Fly |
|
|
regulation of stress activated mapk cascade
|
GO:0032872 |
84 |
0.335
|
|
|
|
negative regulation of secretion
|
GO:0051048 |
58 |
0.335
|
|
|
|
blastoderm segmentation
|
GO:0007350 |
2 |
0.335
|
Fly |
|
|
establishment or maintenance of bipolar cell polarity
|
GO:0061245 |
2 |
0.334
|
Fly |
|
|
insulin like growth factor receptor signaling pathway
|
GO:0048009 |
13 |
0.333
|
|
|
|
regulation of insulin secretion
|
GO:0050796 |
33 |
0.332
|
|
|
|
negative regulation of anoikis
|
GO:2000811 |
15 |
0.330
|
|
|
|
mitotic cell cycle phase transition
|
GO:0044772 |
162 |
0.329
|
Human Fly |
|
|
response to biotic stimulus
|
GO:0009607 |
276 |
0.321
|
|
|
|
regulation of peptidase activity
|
GO:0052547 |
180 |
0.319
|
|
|
|
positive regulation of organ growth
|
GO:0046622 |
2 |
0.319
|
|
|
|
wnt signaling pathway planar cell polarity pathway
|
GO:0060071 |
5 |
0.319
|
|
|
|
regulation of endothelial cell migration
|
GO:0010594 |
67 |
0.318
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.317
|
|
|
|
notch signaling pathway
|
GO:0007219 |
31 |
0.309
|
|
|
|
reactive oxygen species biosynthetic process
|
GO:1903409 |
4 |
0.309
|
|
|
|
neuron projection morphogenesis
|
GO:0048812 |
50 |
0.309
|
Rat |
|
|
blood vessel morphogenesis
|
GO:0048514 |
162 |
0.308
|
|
|
|
spinal cord development
|
GO:0021510 |
4 |
0.305
|
|
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
209 |
0.304
|
|
|
|
stress activated protein kinase signaling cascade
|
GO:0031098 |
94 |
0.300
|
|
|
|
muscle tissue development
|
GO:0060537 |
62 |
0.295
|
Rat |
|
|
actin filament bundle organization
|
GO:0061572 |
54 |
0.293
|
|
