IMP

Process View

Homo sapiens

13 genes annotated in human

Multi-species View

regulation of cardiac muscle tissue development

GO:0055024

Any process that modulates the frequency, rate or extent of cardiac muscle tissue development.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "regulation of cardiac muscle tissue development"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "regulation of cardiac muscle tissue development" (in gray)

Name	Description	Probability	Func Analog Organism
FGFR2	fibroblast growth factor receptor 2	1.000	Mouse
SRF	serum response factor (c-fos serum response element-binding transcription factor)	1.000
FGF1	fibroblast growth factor 1 (acidic)	1.000	Human
TBX5	T-box 5	0.999
FGF10	fibroblast growth factor 10	0.991	Human
NKX2-5	NK2 transcription factor related, locus 5 (Drosophila)	0.991	Mouse
MAGI2	membrane associated guanylate kinase, WW and PDZ domain containing 2	0.988
FGFR1	fibroblast growth factor receptor 1	0.937	Mouse
JAG1	jagged 1	0.895
UCHL1	ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)	0.888
BMPR1A	bone morphogenetic protein receptor, type IA	0.864
LRP6	low density lipoprotein receptor-related protein 6	0.839	Mouse
ERBB3	v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)	0.797
FGF2	fibroblast growth factor 2 (basic)	0.741
EP300	E1A binding protein p300	0.709
NOTCH1	notch 1	0.553	Mouse
HDAC4	histone deacetylase 4	0.416
FSTL1	follistatin-like 1	0.402
MAML1	mastermind-like 1 (Drosophila)	0.301
PDGFRA	platelet-derived growth factor receptor, alpha polypeptide	0.266
TGFB1	transforming growth factor, beta 1	0.250
FGF7	fibroblast growth factor 7	0.242	Human
FZD1	frizzled homolog 1 (Drosophila)	0.235
MEF2A	myocyte enhancer factor 2A	0.221	Human
KAT2B	K(lysine) acetyltransferase 2B	0.215
BMP2	bone morphogenetic protein 2	0.197
HDAC1	histone deacetylase 1	0.176
GATA4	GATA binding protein 4	0.169	Mouse
FRS2	fibroblast growth factor receptor substrate 2	0.161
WWOX	WW domain containing oxidoreductase	0.152
NCK2	NCK adaptor protein 2	0.141
DKK1	dickkopf homolog 1 (Xenopus laevis)	0.140
LRRK2	leucine-rich repeat kinase 2	0.133
PLCG1	phospholipase C, gamma 1	0.128
RUNX1	runt-related transcription factor 1	0.124
TGFB3	transforming growth factor, beta 3	0.120
KRT5	keratin 5	0.114
ANKS1B	ankyrin repeat and sterile alpha motif domain containing 1B	0.112
NOTCH3	notch 3	0.109
CABLES1	Cdk5 and Abl enzyme substrate 1	0.096
FGF8	fibroblast growth factor 8 (androgen-induced)	0.095
HDAC9	histone deacetylase 9	0.091
RBPJ	recombination signal binding protein for immunoglobulin kappa J region	0.086	Mouse
ESR1	estrogen receptor 1	0.085
TP73	tumor protein p73	0.082
SATB2	SATB homeobox 2	0.082
DEAF1	deformed epidermal autoregulatory factor 1 (Drosophila)	0.079
TTR	transthyretin	0.076
SMAD7	SMAD family member 7	0.072
DLG2	discs, large homolog 2 (Drosophila)	0.072
BMP7	bone morphogenetic protein 7	0.068
FGF4	fibroblast growth factor 4	0.063	Human
FOXC2	forkhead box C2 (MFH-1, mesenchyme forkhead 1)	0.063
AXIN1	axin 1	0.060
KLF13	Kruppel-like factor 13	0.059
MYOD1	myogenic differentiation 1	0.058
NR3C1	nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)	0.058	Rat
HIF1A	hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	0.057
NRP1	neuropilin 1	0.053
FZD8	frizzled homolog 8 (Drosophila)	0.049
ATXN1L	ataxin 1-like	0.045
KRT6C	keratin 6C	0.044
TGFB2	transforming growth factor, beta 2	0.044
WNT3A	wingless-type MMTV integration site family, member 3A	0.040
SIRT1	sirtuin 1	0.039
NCOA1	nuclear receptor coactivator 1	0.038
NCOA3	nuclear receptor coactivator 3	0.037
MKL1	megakaryoblastic leukemia (translocation) 1	0.034	Human
HIPK2	homeodomain interacting protein kinase 2	0.032
TRO	trophinin	0.030
WFIKKN2	WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2	0.029
LBX1	ladybird homeobox 1	0.028
KDR	kinase insert domain receptor (a type III receptor tyrosine kinase)	0.025
CDKN2A	cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4)	0.025
FGFR3	fibroblast growth factor receptor 3	0.024
PTGIS	prostaglandin I2 (prostacyclin) synthase	0.024
PDGFB	platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog)	0.023
WNT3	wingless-type MMTV integration site family, member 3	0.022
AR	androgen receptor	0.022
NCOR2	nuclear receptor corepressor 2	0.021
SNAI1	snail homolog 1 (Drosophila)	0.021
AMMECR1	Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1	0.020
DAB2	disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)	0.019
NOG	noggin	0.019	Mouse
FOXF1	forkhead box F1	0.018
AHR	aryl hydrocarbon receptor	0.018
MDM2	Mdm2 p53 binding protein homolog (mouse)	0.018
RPS6KA5	ribosomal protein S6 kinase, 90kDa, polypeptide 5	0.017
SPEN	spen homolog, transcriptional regulator (Drosophila)	0.017
FST	follistatin	0.017
FOXA2	forkhead box A2	0.017
GAB2	GRB2-associated binding protein 2	0.017
GATAD2B	GATA zinc finger domain containing 2B	0.016
NOSTRIN	nitric oxide synthase trafficker	0.016
PPP1R13B	protein phosphatase 1, regulatory (inhibitor) subunit 13B	0.016
VEGFA	vascular endothelial growth factor A	0.016
RAX	retina and anterior neural fold homeobox	0.016
TBX1	T-box 1	0.014	Human
NEDD4	neural precursor cell expressed, developmentally down-regulated 4	0.014
CIR1	corepressor interacting with RBPJ, 1	0.014
TEAD1	TEA domain family member 1 (SV40 transcriptional enhancer factor)	0.014
FGF3	fibroblast growth factor 3	0.014
SEC16A	SEC16 homolog A (S. cerevisiae)	0.014
DLG3	discs, large homolog 3 (Drosophila)	0.014
SMAD1	SMAD family member 1	0.013
NTRK1	neurotrophic tyrosine kinase, receptor, type 1	0.013
DCN	decorin	0.013
CDK2	cyclin-dependent kinase 2	0.013
ARID1B	AT rich interactive domain 1B (SWI1-like)	0.013
S1PR5	sphingosine-1-phosphate receptor 5	0.013
SHC1	SHC (Src homology 2 domain containing) transforming protein 1	0.013
TFAP2A	transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)	0.013
COL2A1	collagen, type II, alpha 1	0.012
POU4F3	POU class 4 homeobox 3	0.012
NR2F2	nuclear receptor subfamily 2, group F, member 2	0.012
PTPN14	protein tyrosine phosphatase, non-receptor type 14	0.012
HAND2	heart and neural crest derivatives expressed 2	0.012
FOXL1	forkhead box L1	0.012
LATS2	LATS, large tumor suppressor, homolog 2 (Drosophila)	0.012
CTGF	connective tissue growth factor	0.012
UTF1	undifferentiated embryonic cell transcription factor 1	0.012
GBX1	gastrulation brain homeobox 1	0.012
DDR2	discoidin domain receptor tyrosine kinase 2	0.012
BDNF	brain-derived neurotrophic factor	0.012
SGCD	sarcoglycan, delta (35kDa dystrophin-associated glycoprotein)	0.012
MYOCD	myocardin	0.012
EPAS1	endothelial PAS domain protein 1	0.011
PIK3R1	phosphoinositide-3-kinase, regulatory subunit 1 (alpha)	0.011
TACC1	transforming, acidic coiled-coil containing protein 1	0.011
PDGFC	platelet derived growth factor C	0.011
ALX4	ALX homeobox 4	0.011
GATA5	GATA binding protein 5	0.011
SFRP5	secreted frizzled-related protein 5	0.011
MYOG	myogenin (myogenic factor 4)	0.010
ENG	endoglin	0.010
JUB	jub, ajuba homolog (Xenopus laevis)	0.010
SIM2	single-minded homolog 2 (Drosophila)	0.010
THBS1	thrombospondin 1	0.010