|
|
membrane raft assembly
|
GO:0001765 |
7 |
0.995
|
|
|
|
neutrophil aggregation
|
GO:0070488 |
2 |
0.958
|
|
|
|
ameboidal type cell migration
|
GO:0001667 |
135 |
0.945
|
|
|
|
regulation of cell adhesion
|
GO:0030155 |
166 |
0.928
|
|
|
|
cell adhesion
|
GO:0007155 |
325 |
0.900
|
|
|
|
cell matrix adhesion
|
GO:0007160 |
85 |
0.864
|
|
|
|
positive regulation of cellular component organization
|
GO:0051130 |
376 |
0.858
|
|
|
|
membrane budding
|
GO:0006900 |
28 |
0.849
|
|
|
|
bleb assembly
|
GO:0032060 |
6 |
0.848
|
|
|
|
single organism cell adhesion
|
GO:0098602 |
179 |
0.823
|
|
|
|
epithelium migration
|
GO:0090132 |
119 |
0.788
|
|
|
|
protein heterotetramerization
|
GO:0051290 |
3 |
0.781
|
|
|
|
regulation of cell morphogenesis
|
GO:0022604 |
153 |
0.767
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
175 |
0.755
|
Human |
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
286 |
0.744
|
|
|
|
positive regulation of developmental process
|
GO:0051094 |
314 |
0.744
|
Zebrafish |
|
|
cell substrate adhesion
|
GO:0031589 |
132 |
0.743
|
|
|
|
actin filament based process
|
GO:0030029 |
224 |
0.737
|
|
|
|
regulation of actin cytoskeleton organization
|
GO:0032956 |
116 |
0.732
|
|
|
|
biological adhesion
|
GO:0022610 |
331 |
0.716
|
|
|
|
integrin mediated signaling pathway
|
GO:0007229 |
32 |
0.709
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
412 |
0.688
|
|
|
|
vesicle organization
|
GO:0016050 |
62 |
0.678
|
|
|
|
chemotaxis
|
GO:0006935 |
157 |
0.654
|
Human |
|
|
regulation of body fluid levels
|
GO:0050878 |
99 |
0.631
|
|
|
|
cellular component morphogenesis
|
GO:0032989 |
314 |
0.631
|
|
|
|
substrate adhesion dependent cell spreading
|
GO:0034446 |
41 |
0.612
|
|
|
|
cell development
|
GO:0048468 |
328 |
0.592
|
Zebrafish |
|
|
single organismal cell cell adhesion
|
GO:0016337 |
148 |
0.589
|
|
|
|
epithelium development
|
GO:0060429 |
227 |
0.585
|
Human |
|
|
membrane assembly
|
GO:0071709 |
10 |
0.584
|
|
|
|
positive regulation of cellular component movement
|
GO:0051272 |
181 |
0.579
|
Human |
|
|
actin filament organization
|
GO:0007015 |
128 |
0.576
|
|
|
|
gtp metabolic process
|
GO:0046039 |
239 |
0.574
|
|
|
|
cardiovascular system development
|
GO:0072358 |
262 |
0.564
|
Zebrafish |
|
|
actin filament based movement
|
GO:0030048 |
17 |
0.553
|
|
|
|
taxis
|
GO:0042330 |
157 |
0.544
|
Human |
|
|
positive regulation of cell differentiation
|
GO:0045597 |
211 |
0.529
|
Zebrafish |
|
|
guanosine containing compound metabolic process
|
GO:1901068 |
244 |
0.509
|
|
|
|
regulation of locomotion
|
GO:0040012 |
329 |
0.509
|
Human |
|
|
regulation of extrinsic apoptotic signaling pathway
|
GO:2001236 |
85 |
0.506
|
Human |
|
|
rho protein signal transduction
|
GO:0007266 |
26 |
0.492
|
|
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
177 |
0.480
|
|
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.480
|
Zebrafish |
|
|
gtp catabolic process
|
GO:0006184 |
237 |
0.479
|
|
|
|
single organism membrane organization
|
GO:0044802 |
268 |
0.459
|
|
|
|
regulation of focal adhesion assembly
|
GO:0051893 |
20 |
0.457
|
|
|
|
regulation of cell migration
|
GO:0030334 |
289 |
0.453
|
Human |
|
|
cation transport
|
GO:0006812 |
331 |
0.449
|
Human |
|
|
regulation of peptidase activity
|
GO:0052547 |
180 |
0.444
|
|
|
|
response to wounding
|
GO:0009611 |
168 |
0.439
|
Zebrafish |
|
|
skeletal system development
|
GO:0001501 |
79 |
0.433
|
|
|
|
positive regulation of cell morphogenesis involved in differentiation
|
GO:0010770 |
50 |
0.432
|
|
|
|
transmembrane transport
|
GO:0055085 |
399 |
0.432
|
Human |
|
|
regulation of cell motility
|
GO:2000145 |
299 |
0.429
|
Human |
|
|
protein heterooligomerization
|
GO:0051291 |
16 |
0.428
|
|
|
|
positive regulation of rho gtpase activity
|
GO:0032321 |
56 |
0.428
|
|
|
|
regulation of rho protein signal transduction
|
GO:0035023 |
79 |
0.414
|
|
|
|
vesicle mediated transport
|
GO:0016192 |
371 |
0.409
|
Human |
|
|
regulation of integrin mediated signaling pathway
|
GO:2001044 |
3 |
0.408
|
|
|
|
wound healing
|
GO:0042060 |
115 |
0.403
|
Zebrafish |
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
391 |
0.398
|
|
|
|
leukocyte migration involved in inflammatory response
|
GO:0002523 |
2 |
0.397
|
|
|
|
endothelial cell migration
|
GO:0043542 |
86 |
0.391
|
|
|
|
protein localization to plasma membrane
|
GO:0072659 |
93 |
0.381
|
|
|
|
positive regulation of organelle organization
|
GO:0010638 |
195 |
0.379
|
|
|
|
positive regulation of actin filament bundle assembly
|
GO:0032233 |
25 |
0.374
|
|
|
|
positive regulation of cell matrix adhesion
|
GO:0001954 |
23 |
0.369
|
|
|
|
regulation of phospholipase a2 activity
|
GO:0032429 |
4 |
0.364
|
|
|
|
granulocyte chemotaxis
|
GO:0071621 |
37 |
0.362
|
Human |
|
|
establishment or maintenance of epithelial cell apical basal polarity
|
GO:0045197 |
1 |
0.360
|
|
|
|
renal system process involved in regulation of blood volume
|
GO:0001977 |
4 |
0.357
|
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
392 |
0.354
|
|
|
|
regulation of serine type endopeptidase activity
|
GO:1900003 |
2 |
0.349
|
|
|
|
neutrophil chemotaxis
|
GO:0030593 |
24 |
0.344
|
Human |
|
|
negative regulation of interleukin 8 secretion
|
GO:2000483 |
2 |
0.342
|
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
412 |
0.341
|
|
|
|
protein tetramerization
|
GO:0051262 |
47 |
0.337
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
0.333
|
|
|
|
granulocyte migration
|
GO:0097530 |
40 |
0.331
|
Human |
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
190 |
0.330
|
|
|
|
regulation of actin filament based process
|
GO:0032970 |
141 |
0.327
|
|
|
|
positive regulation of rac gtpase activity
|
GO:0032855 |
31 |
0.319
|
|
|
|
membrane raft organization
|
GO:0031579 |
10 |
0.319
|
|
|
|
circulatory system development
|
GO:0072359 |
262 |
0.317
|
Zebrafish |
|
|
defense response to other organism
|
GO:0098542 |
129 |
0.317
|
|
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
398 |
0.313
|
|
|
|
positive regulation of substrate adhesion dependent cell spreading
|
GO:1900026 |
15 |
0.309
|
|
|
|
negative regulation of serine type peptidase activity
|
GO:1902572 |
2 |
0.309
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
281 |
0.307
|
|
|
|
actin cytoskeleton organization
|
GO:0030036 |
207 |
0.299
|
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
269 |
0.299
|
|
|
|
i kappab kinase nf kappab signaling
|
GO:0007249 |
166 |
0.296
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
249 |
0.295
|
|
|
|
regulation of cellular component movement
|
GO:0051270 |
334 |
0.294
|
Human |
|
|
cellular response to glucocorticoid stimulus
|
GO:0071385 |
4 |
0.292
|
|
|
|
response to external biotic stimulus
|
GO:0043207 |
261 |
0.292
|
|
|
|
regulation of vasculogenesis
|
GO:2001212 |
3 |
0.290
|
|
|
|
epithelial cell migration
|
GO:0010631 |
119 |
0.286
|
|
|
|
positive regulation of cell proliferation
|
GO:0008284 |
301 |
0.286
|
|
|
|
epithelial cell differentiation
|
GO:0030855 |
141 |
0.281
|
Human |
|
|
positive regulation of i kappab kinase nf kappab signaling
|
GO:0043123 |
132 |
0.280
|
|
|
|
regulation of interleukin 8 secretion
|
GO:2000482 |
13 |
0.270
|
|
|
|
positive regulation of cell adhesion
|
GO:0045785 |
84 |
0.264
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
422 |
0.259
|
|
|
|
negative regulation of phospholipase activity
|
GO:0010519 |
3 |
0.259
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.256
|
|
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
336 |
0.255
|
|
|
|
regulation of serine type peptidase activity
|
GO:1902571 |
2 |
0.254
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
331 |
0.250
|
|
|
|
cell morphogenesis involved in differentiation
|
GO:0000904 |
144 |
0.247
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
405 |
0.243
|
|
|
|
skin development
|
GO:0043588 |
76 |
0.242
|
|
|
|
secretion
|
GO:0046903 |
254 |
0.239
|
|
|
|
regulation of cell substrate adhesion
|
GO:0010810 |
68 |
0.235
|
|
|
|
protein localization to membrane
|
GO:0072657 |
160 |
0.232
|
|
|
|
regulation of stress fiber assembly
|
GO:0051492 |
32 |
0.229
|
|
|
|
actomyosin structure organization
|
GO:0031032 |
59 |
0.221
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
78 |
0.218
|
|
|
|
positive regulation of cell junction assembly
|
GO:1901890 |
11 |
0.216
|
|
|
|
cell morphogenesis
|
GO:0000902 |
296 |
0.214
|
|
|
|
establishment of protein localization to plasma membrane
|
GO:0090002 |
68 |
0.213
|
|
|
|
positive regulation of cell motility
|
GO:2000147 |
177 |
0.211
|
Human |
|
|
neutrophil migration
|
GO:1990266 |
25 |
0.211
|
Human |
|
|
leukocyte migration
|
GO:0050900 |
107 |
0.207
|
Human |
|
|
interleukin 1 alpha secretion
|
GO:0050703 |
1 |
0.206
|
|
|
|
positive regulation of phosphorylation
|
GO:0042327 |
394 |
0.206
|
|
|
|
nervous system development
|
GO:0007399 |
293 |
0.204
|
Zebrafish |
|
|
hemostasis
|
GO:0007599 |
76 |
0.204
|
|
|
|
response to other organism
|
GO:0051707 |
261 |
0.202
|
|
|
|
regulation of cell morphogenesis involved in differentiation
|
GO:0010769 |
83 |
0.201
|
|
|
|
negative regulation of serine type endopeptidase activity
|
GO:1900004 |
2 |
0.200
|
|
|
|
actin filament bundle organization
|
GO:0061572 |
54 |
0.197
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
264 |
0.195
|
|
|
|
striated muscle contraction
|
GO:0006941 |
52 |
0.194
|
|
|
|
negative regulation of catalytic activity
|
GO:0043086 |
335 |
0.190
|
|
|
|
cell chemotaxis
|
GO:0060326 |
112 |
0.190
|
Human |
|
|
negative regulation of cellular component movement
|
GO:0051271 |
106 |
0.186
|
|
|
|
metal ion transport
|
GO:0030001 |
272 |
0.185
|
Human |
|
|
regulation of actin filament bundle assembly
|
GO:0032231 |
36 |
0.184
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
227 |
0.183
|
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
411 |
0.180
|
|
|
|
post embryonic development
|
GO:0009791 |
2 |
0.173
|
|
|
|
cell projection organization
|
GO:0030030 |
252 |
0.171
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
284 |
0.169
|
|
|
|
protein oligomerization
|
GO:0051259 |
173 |
0.168
|
|
|
|
response to xenobiotic stimulus
|
GO:0009410 |
30 |
0.168
|
|
|
|
positive regulation of integrin mediated signaling pathway
|
GO:2001046 |
2 |
0.167
|
|
|
|
positive regulation of cell substrate adhesion
|
GO:0010811 |
37 |
0.164
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
204 |
0.163
|
|
|
|
coagulation
|
GO:0050817 |
78 |
0.161
|
|
|
|
tissue migration
|
GO:0090130 |
119 |
0.159
|
|
|
|
myeloid leukocyte migration
|
GO:0097529 |
62 |
0.155
|
Human |
|
|
blood vessel morphogenesis
|
GO:0048514 |
162 |
0.154
|
Zebrafish |
|
|
ossification
|
GO:0001503 |
121 |
0.153
|
|
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
230 |
0.152
|
|
|
|
endomembrane system organization
|
GO:0010256 |
196 |
0.149
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
246 |
0.147
|
|
|
|
stress fiber assembly
|
GO:0043149 |
40 |
0.147
|
|
|
|
positive regulation of map kinase activity
|
GO:0043406 |
80 |
0.144
|
|
|
|
regulation of blood coagulation
|
GO:0030193 |
42 |
0.143
|
|
|
|
ion transmembrane transport
|
GO:0034220 |
338 |
0.142
|
Human |
|
|
calcium ion transport
|
GO:0006816 |
147 |
0.141
|
Human |
|
|
regulation of actin filament polymerization
|
GO:0030833 |
50 |
0.139
|
|
|
|
membrane organization
|
GO:0061024 |
292 |
0.138
|
|
|
|
anatomical structure formation involved in morphogenesis
|
GO:0048646 |
284 |
0.133
|
Zebrafish |
|
|
divalent metal ion transport
|
GO:0070838 |
152 |
0.133
|
Human |
|
|
negative regulation of proteolysis
|
GO:0045861 |
132 |
0.131
|
|
|
|
leukocyte cell cell adhesion
|
GO:0007159 |
37 |
0.131
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
412 |
0.131
|
|
|
|
muscle contraction
|
GO:0006936 |
73 |
0.129
|
|
|
|
regulation of response to wounding
|
GO:1903034 |
101 |
0.129
|
Zebrafish |
|
|
positive regulation of purine nucleotide metabolic process
|
GO:1900544 |
227 |
0.128
|
|
|
|
positive regulation of peptidase activity
|
GO:0010952 |
88 |
0.127
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
313 |
0.127
|
|
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
119 |
0.127
|
|
|
|
regulation of wound healing
|
GO:0061041 |
56 |
0.126
|
Zebrafish |
|
|
peptidyl tyrosine modification
|
GO:0018212 |
170 |
0.126
|
|
|
|
cell matrix adhesion involved in ameboidal cell migration
|
GO:0003366 |
2 |
0.125
|
|
|
|
protein processing
|
GO:0016485 |
226 |
0.123
|
|
|
|
determination of adult lifespan
|
GO:0008340 |
2 |
0.121
|
|
|
|
regulation of purine nucleotide catabolic process
|
GO:0033121 |
205 |
0.121
|
|
|
|
cytokine secretion
|
GO:0050663 |
64 |
0.120
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
437 |
0.118
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
7 |
0.117
|
|
|
|
regulation of gtpase activity
|
GO:0043087 |
180 |
0.117
|
|
|
|
epidermal cell differentiation
|
GO:0009913 |
45 |
0.115
|
|
|
|
positive regulation of cell migration
|
GO:0030335 |
172 |
0.115
|
Human |
|
|
glycosyl compound catabolic process
|
GO:1901658 |
413 |
0.114
|
|
|
|
system process
|
GO:0003008 |
349 |
0.114
|
|
|
|
positive regulation of cellular component biogenesis
|
GO:0044089 |
158 |
0.112
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
268 |
0.110
|
Human |
|
|
cellular response to organic cyclic compound
|
GO:0071407 |
127 |
0.109
|
|
|
|
regulation of protein localization
|
GO:0032880 |
296 |
0.109
|
|
|
|
regulation of cell matrix adhesion
|
GO:0001952 |
42 |
0.108
|
|
|
|
interleukin 1 alpha production
|
GO:0032610 |
2 |
0.107
|
|
|
|
actin mediated cell contraction
|
GO:0070252 |
12 |
0.104
|
|
|
|
hematopoietic or lymphoid organ development
|
GO:0048534 |
186 |
0.104
|
Mouse |
|
|
signal transduction by phosphorylation
|
GO:0023014 |
297 |
0.101
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
391 |
0.099
|
|
|
|
regulation of substrate adhesion dependent cell spreading
|
GO:1900024 |
19 |
0.098
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
391 |
0.097
|
|
|
|
establishment of protein localization to membrane
|
GO:0090150 |
121 |
0.096
|
|
|
|
positive regulation of gtpase activity
|
GO:0043547 |
166 |
0.095
|
|
|
|
cellular homeostasis
|
GO:0019725 |
196 |
0.095
|
|
|
|
autophagy
|
GO:0006914 |
88 |
0.094
|
|
|
|
positive regulation of gtp catabolic process
|
GO:0033126 |
166 |
0.093
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
398 |
0.092
|
|
|
|
epidermis development
|
GO:0008544 |
59 |
0.092
|
|
|
|
positive regulation of apoptotic signaling pathway
|
GO:2001235 |
70 |
0.091
|
|
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
209 |
0.091
|
|
|
|
striated muscle tissue development
|
GO:0014706 |
59 |
0.091
|
Zebrafish |
|
|
cytokine production
|
GO:0001816 |
247 |
0.091
|
|
|
|
positive regulation of cytoskeleton organization
|
GO:0051495 |
83 |
0.090
|
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
406 |
0.089
|
|
|
|
regulation of wnt signaling pathway
|
GO:0030111 |
123 |
0.088
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
353 |
0.088
|
|
|
|
xenobiotic metabolic process
|
GO:0006805 |
28 |
0.087
|
|
|
|
response to biotic stimulus
|
GO:0009607 |
276 |
0.086
|
|
|
|
positive regulation of purine nucleotide catabolic process
|
GO:0033123 |
185 |
0.086
|
|
|
|
vasculature development
|
GO:0001944 |
181 |
0.085
|
Zebrafish |
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
0.085
|
|
|
|
regulation of ion transport
|
GO:0043269 |
189 |
0.085
|
Human |
|
|
motor neuron axon guidance
|
GO:0008045 |
2 |
0.084
|
|
|
|
regulation of rubidium ion transport
|
GO:2000680 |
3 |
0.083
|
|
|
|
plasma membrane organization
|
GO:0007009 |
115 |
0.080
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
263 |
0.079
|
|
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
0.079
|
Human |
|
|
interleukin 1 production
|
GO:0032612 |
26 |
0.079
|
|
|
|
endosomal transport
|
GO:0016197 |
129 |
0.079
|
|
|
|
negative regulation of locomotion
|
GO:0040013 |
118 |
0.078
|
|
|
|
neuron projection development
|
GO:0031175 |
106 |
0.078
|
|
|
|
blood coagulation
|
GO:0007596 |
76 |
0.077
|
|
|
|
regulation of vesicle mediated transport
|
GO:0060627 |
130 |
0.076
|
Human |
|
|
regulation of stress activated protein kinase signaling cascade
|
GO:0070302 |
85 |
0.075
|
|
|
|
positive regulation of nucleotide catabolic process
|
GO:0030813 |
185 |
0.075
|
|
|
|
blood vessel endothelial cell migration
|
GO:0043534 |
42 |
0.075
|
|
|
|
negative regulation of sequence specific dna binding transcription factor activity
|
GO:0043433 |
89 |
0.075
|
|
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
155 |
0.074
|
|
|
|
negative regulation of programmed cell death
|
GO:0043069 |
321 |
0.073
|
Human |
|
|
negative regulation of endopeptidase activity
|
GO:0010951 |
84 |
0.073
|
|
|
|
positive regulation of cell projection organization
|
GO:0031346 |
64 |
0.073
|
|
|
|
female gamete generation
|
GO:0007292 |
2 |
0.072
|
|
|
|
neutrophil clearance
|
GO:0097350 |
1 |
0.071
|
|
|
|
single organism reproductive process
|
GO:0044702 |
98 |
0.071
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
41 |
0.070
|
|
|
|
urogenital system development
|
GO:0001655 |
65 |
0.067
|
|
|
|
sequestering of calcium ion
|
GO:0051208 |
17 |
0.067
|
|
|
|
single organism membrane fusion
|
GO:0044801 |
37 |
0.066
|
|
|
|
response to metal ion
|
GO:0010038 |
84 |
0.065
|
|
|
|
positive regulation of vesicle fusion
|
GO:0031340 |
4 |
0.065
|
|
|
|
multicellular organismal aging
|
GO:0010259 |
3 |
0.065
|
|
|
|
cell part morphogenesis
|
GO:0032990 |
137 |
0.065
|
|
|
|
striated muscle cell differentiation
|
GO:0051146 |
43 |
0.063
|
Zebrafish |
|
|
interleukin 1 secretion
|
GO:0050701 |
18 |
0.063
|
|
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
239 |
0.063
|
|
|
|
positive regulation of catabolic process
|
GO:0009896 |
310 |
0.063
|
|
|
|
neurofilament bundle assembly
|
GO:0033693 |
2 |
0.062
|
|
|
|
response to growth factor
|
GO:0070848 |
205 |
0.062
|
|
|
|
positive regulation of focal adhesion assembly
|
GO:0051894 |
11 |
0.062
|
|
|
|
cellular response to xenobiotic stimulus
|
GO:0071466 |
29 |
0.061
|
|
|
|
negative regulation of cell migration
|
GO:0030336 |
102 |
0.061
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
314 |
0.061
|
|
|
|
embryonic viscerocranium morphogenesis
|
GO:0048703 |
1 |
0.060
|
|
|
|
leukocyte differentiation
|
GO:0002521 |
98 |
0.060
|
Mouse |
|
|
divalent inorganic cation transport
|
GO:0072511 |
158 |
0.060
|
Human |
|
|
cell projection assembly
|
GO:0030031 |
126 |
0.060
|
|
|
|
endocytosis
|
GO:0006897 |
159 |
0.059
|
Human |
|
|
positive regulation of cysteine type endopeptidase activity
|
GO:2001056 |
79 |
0.059
|
|
|
|
secretion by cell
|
GO:0032940 |
226 |
0.059
|
|
|
|
maintenance of cell polarity
|
GO:0030011 |
2 |
0.058
|
|
|
|
peptide cross linking
|
GO:0018149 |
12 |
0.058
|
|
|
|
purine containing compound biosynthetic process
|
GO:0072522 |
88 |
0.057
|
|
|
|
response to lipid
|
GO:0033993 |
206 |
0.057
|
|
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
119 |
0.056
|
Human |
|
|
regulation of protein polymerization
|
GO:0032271 |
63 |
0.056
|
|
|
|
regulation of response to external stimulus
|
GO:0032101 |
222 |
0.056
|
|
|
|
nucleoside catabolic process
|
GO:0009164 |
408 |
0.056
|
|
|
|
organelle fusion
|
GO:0048284 |
36 |
0.056
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
73 |
0.055
|
|
|
|
cellular cation homeostasis
|
GO:0030003 |
163 |
0.054
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.054
|
|
|
|
keratinocyte differentiation
|
GO:0030216 |
36 |
0.054
|
|
|
|
blood circulation
|
GO:0008015 |
113 |
0.054
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
393 |
0.054
|
|
|
|
zymogen activation
|
GO:0031638 |
70 |
0.054
|
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
404 |
0.054
|
|
|
|
activation of protein kinase activity
|
GO:0032147 |
90 |
0.054
|
|
|
|
interleukin 8 secretion
|
GO:0072606 |
14 |
0.054
|
|
|
|
organelle assembly
|
GO:0070925 |
176 |
0.054
|
|
|
|
cation homeostasis
|
GO:0055080 |
189 |
0.053
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.053
|
|
|
|
regulation of stress activated mapk cascade
|
GO:0032872 |
84 |
0.053
|
|
|
|
positive regulation of nucleoside metabolic process
|
GO:0045979 |
186 |
0.052
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
408 |
0.051
|
|
|
|
neurogenesis
|
GO:0022008 |
169 |
0.051
|
Zebrafish |
|
|
rubidium ion transport
|
GO:0035826 |
4 |
0.050
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
411 |
0.050
|
|
|
|
actin filament bundle assembly
|
GO:0051017 |
54 |
0.050
|
|
|
|
positive regulation of actin filament polymerization
|
GO:0030838 |
38 |
0.049
|
|
|
|
positive regulation of stress activated protein kinase signaling cascade
|
GO:0070304 |
61 |
0.048
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
430 |
0.048
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
379 |
0.048
|
|
|
|
engulfment of apoptotic cell
|
GO:0043652 |
2 |
0.048
|
|
|
|
cell projection morphogenesis
|
GO:0048858 |
129 |
0.047
|
|
|
|
regulation of rho gtpase activity
|
GO:0032319 |
66 |
0.046
|
|
|
|
purine nucleotide biosynthetic process
|
GO:0006164 |
84 |
0.046
|
|
|
|
brain development
|
GO:0007420 |
97 |
0.046
|
|
|
|
maintenance of location
|
GO:0051235 |
112 |
0.046
|
|
|
|
regulation of vasculature development
|
GO:1901342 |
97 |
0.045
|
|
|
|
cytokinesis
|
GO:0000910 |
96 |
0.045
|
|
|
|
calcium independent cell matrix adhesion
|
GO:0007161 |
1 |
0.045
|
|
|
|
negative regulation of apoptotic signaling pathway
|
GO:2001234 |
97 |
0.045
|
Human |
|
|
regulation of cysteine type endopeptidase activity
|
GO:2000116 |
127 |
0.045
|
|
|
|
negative regulation of cell motility
|
GO:2000146 |
104 |
0.045
|
|
|
|
calcium ion transmembrane transport
|
GO:0070588 |
76 |
0.045
|
|
|
|
regulation of cell cell adhesion
|
GO:0022407 |
57 |
0.044
|
|
|
|
substantia nigra development
|
GO:0021762 |
45 |
0.044
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
293 |
0.044
|
|
|
|
positive regulation of transport
|
GO:0051050 |
336 |
0.044
|
Human |
|
|
membrane biogenesis
|
GO:0044091 |
13 |
0.044
|
|
|
|
protein secretion
|
GO:0009306 |
98 |
0.044
|
|
|
|
negative regulation of catabolic process
|
GO:0009895 |
104 |
0.043
|
|
|
|
negative regulation of protein secretion
|
GO:0050709 |
29 |
0.043
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
92 |
0.043
|
Zebrafish |
|
|
response to fungus
|
GO:0009620 |
4 |
0.043
|
|
|
|
ectoderm development
|
GO:0007398 |
3 |
0.043
|
|
|
|
protein maturation
|
GO:0051604 |
233 |
0.043
|
|
|
|
intrinsic apoptotic signaling pathway
|
GO:0097193 |
127 |
0.043
|
|
|
|
metal ion homeostasis
|
GO:0055065 |
169 |
0.043
|
|
|
|
myeloid cell differentiation
|
GO:0030099 |
117 |
0.043
|
|
|
|
response to mercury ion
|
GO:0046689 |
4 |
0.042
|
|
|
|
response to inorganic substance
|
GO:0010035 |
127 |
0.042
|
|
|
|
cellular response to lipid
|
GO:0071396 |
127 |
0.042
|
|
|
|
extracellular structure organization
|
GO:0043062 |
41 |
0.042
|
|
|
|
growth
|
GO:0040007 |
202 |
0.042
|
|
|
|
oogenesis
|
GO:0048477 |
2 |
0.042
|
|
|
|
response to calcium ion
|
GO:0051592 |
46 |
0.042
|
|
|
|
positive regulation of myeloid cell apoptotic process
|
GO:0033034 |
2 |
0.041
|
|
|
|
cellular protein complex assembly
|
GO:0043623 |
188 |
0.041
|
|
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
317 |
0.041
|
|
|
|
cellular metal ion homeostasis
|
GO:0006875 |
146 |
0.041
|
|
|
|
activation of mapk activity
|
GO:0000187 |
45 |
0.041
|
|
|
|
response to oxygen containing compound
|
GO:1901700 |
369 |
0.041
|
|
|
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
170 |
0.041
|
|
|
|
neutrophil homeostasis
|
GO:0001780 |
3 |
0.041
|
|
|
|
osteoclast development
|
GO:0036035 |
2 |
0.041
|
|
|
|
monocyte chemotaxis
|
GO:0002548 |
20 |
0.041
|
Human |
|
|
tissue morphogenesis
|
GO:0048729 |
96 |
0.041
|
|
|
|
lipid localization
|
GO:0010876 |
106 |
0.040
|
|
|
|
response to radiation
|
GO:0009314 |
151 |
0.040
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
244 |
0.040
|
|
|
|
extracellular matrix organization
|
GO:0030198 |
41 |
0.040
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
286 |
0.039
|
|
|
|
negative regulation of hydrolase activity
|
GO:0051346 |
182 |
0.039
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
289 |
0.039
|
|
|
|
regulation of cellular response to growth factor stimulus
|
GO:0090287 |
76 |
0.039
|
|
|
|
regulation of mitochondrial membrane potential
|
GO:0051881 |
23 |
0.039
|
|
|
|
prostate gland stromal morphogenesis
|
GO:0060741 |
1 |
0.038
|
|
|
|
cellular ion homeostasis
|
GO:0006873 |
168 |
0.038
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
6 |
0.038
|
|
|
|
muscle cell differentiation
|
GO:0042692 |
63 |
0.038
|
Zebrafish Mouse |
|
|
osteoblast differentiation
|
GO:0001649 |
92 |
0.038
|
|
|
|
immunoglobulin biosynthetic process
|
GO:0002378 |
2 |
0.038
|
|
|
|
sulfur compound metabolic process
|
GO:0006790 |
101 |
0.038
|
|
|
|
muscle cell development
|
GO:0055001 |
29 |
0.038
|
Zebrafish |
|
|
actin polymerization or depolymerization
|
GO:0008154 |
56 |
0.038
|
|
|
|
regulation of cell projection organization
|
GO:0031344 |
107 |
0.037
|
|
|
|
single organism cellular localization
|
GO:1902580 |
332 |
0.037
|
|
|
|
sequestering of metal ion
|
GO:0051238 |
24 |
0.037
|
|
|
|
amine metabolic process
|
GO:0009308 |
44 |
0.037
|
|
|
|
regulation of dna metabolic process
|
GO:0051052 |
153 |
0.037
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.036
|
|
|
|
muscle organ development
|
GO:0007517 |
56 |
0.036
|
Zebrafish |
|
|
response to organic cyclic compound
|
GO:0014070 |
204 |
0.036
|
|
|
|
somitogenesis
|
GO:0001756 |
2 |
0.036
|
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
180 |
0.035
|
|
|
|
mapk cascade
|
GO:0000165 |
288 |
0.035
|
|
|
|
circulatory system process
|
GO:0003013 |
113 |
0.034
|
|
|
|
regulation of protein catabolic process
|
GO:0042176 |
155 |
0.034
|
|
|
|
regulation of endopeptidase activity
|
GO:0052548 |
170 |
0.034
|
|
|
|
muscle system process
|
GO:0003012 |
81 |
0.034
|
|
|
|
activation of cysteine type endopeptidase activity
|
GO:0097202 |
57 |
0.034
|
|
|
|
response to light stimulus
|
GO:0009416 |
87 |
0.033
|
|
|
|
angiogenesis
|
GO:0001525 |
147 |
0.033
|
Zebrafish |
|
|
regulation of anatomical structure size
|
GO:0090066 |
101 |
0.033
|
|
|
|
protein homooligomerization
|
GO:0051260 |
100 |
0.033
|
|
|
|
negative regulation of immune system process
|
GO:0002683 |
136 |
0.033
|
|
|
|
positive regulation of ras gtpase activity
|
GO:0032320 |
117 |
0.033
|
|
|
|
homotypic cell cell adhesion
|
GO:0034109 |
47 |
0.033
|
|
|
|
nerve development
|
GO:0021675 |
4 |
0.033
|
|
|
|
cell adhesion mediated by integrin
|
GO:0033627 |
27 |
0.032
|
|
|
|
post embryonic organ development
|
GO:0048569 |
1 |
0.032
|
|
|
|
positive regulation of neutrophil apoptotic process
|
GO:0033031 |
1 |
0.032
|
|
|
|
cell activation
|
GO:0001775 |
213 |
0.032
|
Human Mouse |
|
|
focal adhesion assembly
|
GO:0048041 |
30 |
0.032
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
179 |
0.031
|
|
|
|
heterotypic cell cell adhesion
|
GO:0034113 |
28 |
0.031
|
|
|
|
cellular component assembly involved in morphogenesis
|
GO:0010927 |
73 |
0.031
|
|
|
|
blood vessel development
|
GO:0001568 |
172 |
0.031
|
Zebrafish |
|
|
ribonucleotide catabolic process
|
GO:0009261 |
405 |
0.031
|
|
|
|
cation transmembrane transport
|
GO:0098655 |
238 |
0.031
|
|
|
|
positive regulation of antigen receptor mediated signaling pathway
|
GO:0050857 |
3 |
0.031
|
|
|
|
reproductive process
|
GO:0022414 |
106 |
0.030
|
|
|
|
platelet activation
|
GO:0030168 |
44 |
0.030
|
|
|
|
head development
|
GO:0060322 |
108 |
0.030
|
|
|
|
regulation of secretion
|
GO:0051046 |
194 |
0.030
|
|
|
|
regulation of cell development
|
GO:0060284 |
161 |
0.029
|
Zebrafish |
|
|
regulation of metalloenzyme activity
|
GO:0048552 |
3 |
0.029
|
|
|
|
axon development
|
GO:0061564 |
34 |
0.029
|
|
|
|
adenylate cyclase modulating g protein coupled receptor signaling pathway
|
GO:0007188 |
43 |
0.029
|
|
|
|
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger
|
GO:0007187 |
43 |
0.029
|
|
|
|
interleukin 8 production
|
GO:0032637 |
51 |
0.029
|
|
|
|
cellular response to nutrient
|
GO:0031670 |
12 |
0.029
|
|
|
|
regulation of small gtpase mediated signal transduction
|
GO:0051056 |
156 |
0.029
|
|
|
|
muscle structure development
|
GO:0061061 |
98 |
0.029
|
Zebrafish Mouse |
|
|
stress activated protein kinase signaling cascade
|
GO:0031098 |
94 |
0.028
|
|
|
|
regulation of t cell proliferation
|
GO:0042129 |
42 |
0.028
|
Human |
|
|
vesicle fusion
|
GO:0006906 |
17 |
0.028
|
|
|
|
activation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0006919 |
49 |
0.028
|
|
|
|
calcium ion homeostasis
|
GO:0055074 |
122 |
0.028
|
|
|
|
regulation of ras gtpase activity
|
GO:0032318 |
128 |
0.028
|
|
|
|
positive regulation of axon extension
|
GO:0045773 |
4 |
0.027
|
|
|
|
endodermal cell differentiation
|
GO:0035987 |
31 |
0.027
|
|
|
|
negative regulation of protein maturation
|
GO:1903318 |
142 |
0.027
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
190 |
0.027
|
|
|
|
regulation of nucleotide catabolic process
|
GO:0030811 |
205 |
0.027
|
|
|
|
dna recombination
|
GO:0006310 |
77 |
0.027
|
|
|
|
response to acid chemical
|
GO:0001101 |
66 |
0.027
|
|
|
|
myosin filament assembly
|
GO:0031034 |
2 |
0.027
|
|
|
|
response to hormone
|
GO:0009725 |
175 |
0.027
|
|
|
|
cell morphogenesis involved in neuron differentiation
|
GO:0048667 |
44 |
0.027
|
|
|
|
positive regulation of nervous system development
|
GO:0051962 |
54 |
0.027
|
Zebrafish |
|
|
neuron development
|
GO:0048666 |
113 |
0.026
|
|
|
|
regulation of coagulation
|
GO:0050818 |
44 |
0.026
|
|
|
|
defense response to fungus
|
GO:0050832 |
4 |
0.026
|
|
|
|
regulation of cellular component size
|
GO:0032535 |
82 |
0.026
|
|
|
|
negative regulation of developmental process
|
GO:0051093 |
247 |
0.026
|
|
|
|
drinking behavior
|
GO:0042756 |
1 |
0.026
|
|
|
|
leukocyte aggregation
|
GO:0070486 |
8 |
0.026
|
|
|
|
response to steroid hormone
|
GO:0048545 |
80 |
0.026
|
|
|
|
lipid transport
|
GO:0006869 |
90 |
0.025
|
|
|
|
regeneration
|
GO:0031099 |
4 |
0.025
|
|
|
|
positive regulation of adherens junction organization
|
GO:1903393 |
12 |
0.025
|
|
|
|
generation of neurons
|
GO:0048699 |
152 |
0.025
|
Zebrafish |
|
|
regulation of proteasomal protein catabolic process
|
GO:0061136 |
87 |
0.025
|
|
|
|
regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043281 |
116 |
0.025
|
|
|
|
endoderm formation
|
GO:0001706 |
33 |
0.025
|
|
|
|
regulation of actin polymerization or depolymerization
|
GO:0008064 |
56 |
0.024
|
|
|
|
negative regulation of phospholipase a2 activity
|
GO:1900138 |
1 |
0.024
|
|
|
|
aging
|
GO:0007568 |
66 |
0.024
|
|
|
|
negative regulation of cell adhesion
|
GO:0007162 |
64 |
0.024
|
|
|
|
vitamin transmembrane transport
|
GO:0035461 |
4 |
0.024
|
|
|
|
cell migration involved in gastrulation
|
GO:0042074 |
1 |
0.023
|
|
|
|
regulation of defense response
|
GO:0031347 |
154 |
0.023
|
|
|
|
neural nucleus development
|
GO:0048857 |
47 |
0.023
|
|
|
|
regulation of nervous system development
|
GO:0051960 |
88 |
0.023
|
Zebrafish |
|
|
positive regulation of stress activated mapk cascade
|
GO:0032874 |
60 |
0.023
|
|
|
|
regulation of map kinase activity
|
GO:0043405 |
108 |
0.023
|
|
|
|
negative regulation of cellular catabolic process
|
GO:0031330 |
83 |
0.023
|
|
|
|
regulation of cytokine secretion
|
GO:0050707 |
57 |
0.023
|
|
|
|
regulation of inflammatory response
|
GO:0050727 |
46 |
0.023
|
|
|
|
cellular response to acid chemical
|
GO:0071229 |
44 |
0.023
|
|
|
|
regulation of protein localization to plasma membrane
|
GO:1903076 |
40 |
0.023
|
|
|
|
actin filament polymerization
|
GO:0030041 |
45 |
0.023
|
|
|
|
regulation of lymphocyte proliferation
|
GO:0050670 |
64 |
0.022
|
Human |
|
|
negative regulation of homeostatic process
|
GO:0032845 |
59 |
0.022
|
|
|
|
adherens junction assembly
|
GO:0034333 |
34 |
0.022
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
262 |
0.022
|
|
|
|
cell substrate adherens junction assembly
|
GO:0007045 |
30 |
0.022
|
|
|
|
cellular calcium ion homeostasis
|
GO:0006874 |
117 |
0.021
|
|
|
|
glial cell migration
|
GO:0008347 |
4 |
0.021
|
|
|
|
negative regulation of wound healing
|
GO:0061045 |
25 |
0.021
|
|
|
|
striated muscle myosin thick filament assembly
|
GO:0071688 |
2 |
0.021
|
|
|
|
negative regulation of blood coagulation
|
GO:0030195 |
22 |
0.021
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
267 |
0.021
|
|
|
|
negative regulation of immune response
|
GO:0050777 |
40 |
0.021
|
|
|
|
negative regulation of rho gtpase activity
|
GO:0034259 |
4 |
0.021
|
|
|
|
protein catabolic process
|
GO:0030163 |
325 |
0.021
|
|
|
|
bone development
|
GO:0060348 |
26 |
0.020
|
|
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.020
|
Human |
|
|
regulation of i kappab kinase nf kappab signaling
|
GO:0043122 |
162 |
0.020
|
|
|
|
positive regulation of locomotion
|
GO:0040017 |
186 |
0.020
|
Human |
|
|
regulation of binding
|
GO:0051098 |
111 |
0.020
|
|
|
|
organic hydroxy compound transport
|
GO:0015850 |
63 |
0.020
|
|
|
|
defense response
|
GO:0006952 |
315 |
0.020
|
|
|
|
wnt signaling pathway
|
GO:0016055 |
156 |
0.020
|
|
|
|
axonogenesis
|
GO:0007409 |
31 |
0.020
|
|
|
|
regulation of protein maturation
|
GO:1903317 |
150 |
0.020
|
|
|
|
regulation of interleukin 8 production
|
GO:0032677 |
49 |
0.020
|
|
