IMP

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Homo sapiens

24 genes annotated in human

neutrophil chemotaxis

The directed movement of a neutrophil cell, the most numerous polymorphonuclear leukocyte found in the blood, in response to an external stimulus, usually an infection or wounding.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "neutrophil chemotaxis"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "neutrophil chemotaxis" (in gray)

Name	Description	Probability	Func Analog Organism
CCR5	chemokine (C-C motif) receptor 5	0.989	Human
RAC1	ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)	0.977
IL8	interleukin 8	0.975
S100A6	S100 calcium binding protein A6	0.967	Human
S100A11	S100 calcium binding protein A11	0.948	Human
CXCL1	chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)	0.932	Human Mouse Rat
CCL5	chemokine (C-C motif) ligand 5	0.918	Human
CXCL2	chemokine (C-X-C motif) ligand 2	0.911	Human Mouse Rat
S100A9	S100 calcium binding protein A9	0.864
CCL2	chemokine (C-C motif) ligand 2	0.835	Human
CCL4	chemokine (C-C motif) ligand 4	0.829	Human
ARHGDIB	Rho GDP dissociation inhibitor (GDI) beta	0.806
S100B	S100 calcium binding protein B	0.793	Human
ITGB1	integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)	0.764	Human
S100A4	S100 calcium binding protein A4	0.760	Human
CDC42	cell division cycle 42 (GTP binding protein, 25kDa)	0.758	Human
DPP4	dipeptidyl-peptidase 4	0.712
MDM2	Mdm2 p53 binding protein homolog (mouse)	0.664
CXCL10	chemokine (C-X-C motif) ligand 10	0.639	Human
IL1B	interleukin 1, beta	0.631	Mouse Rat
NCF2	neutrophil cytosolic factor 2	0.613
ANXA2	annexin A2	0.576
CXCL3	chemokine (C-X-C motif) ligand 3	0.552	Human Mouse Rat
FLNA	filamin A, alpha	0.537
MPZL2	myelin protein zero-like 2	0.514	Human
S100A8	S100 calcium binding protein A8	0.513
CXCL9	chemokine (C-X-C motif) ligand 9	0.489	Human
TIMP1	TIMP metallopeptidase inhibitor 1	0.466
MPZL3	myelin protein zero-like 3	0.460	Human
CCR1	chemokine (C-C motif) receptor 1	0.448	Human
S100A1	S100 calcium binding protein A1	0.429	Human
GRB2	growth factor receptor-bound protein 2	0.388
IL6	interleukin 6 (interferon, beta 2)	0.367
CXCR4	chemokine (C-X-C motif) receptor 4	0.365	Human Zebrafish
PTGS2	prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)	0.356
SYK	spleen tyrosine kinase	0.353
ICAM1	intercellular adhesion molecule 1	0.345
LGALS1	lectin, galactoside-binding, soluble, 1	0.344	Human
ERBB2	v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)	0.330
PLEK	pleckstrin	0.326
CCL22	chemokine (C-C motif) ligand 22	0.324	Human
FN1	fibronectin 1	0.323
FCER1G	Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide	0.314	Mouse
PIK3R1	phosphoinositide-3-kinase, regulatory subunit 1 (alpha)	0.300
CD63	CD63 molecule	0.278
SLA	Src-like-adaptor	0.276
CCL19	chemokine (C-C motif) ligand 19	0.274
IL2RB	interleukin 2 receptor, beta	0.274
PLAUR	plasminogen activator, urokinase receptor	0.251
CCL20	chemokine (C-C motif) ligand 20	0.246	Human
MTOR	mechanistic target of rapamycin (serine/threonine kinase)	0.245
NCF1	neutrophil cytosolic factor 1	0.236
VCAM1	vascular cell adhesion molecule 1	0.227
EMP3	epithelial membrane protein 3	0.218
NCF4	neutrophil cytosolic factor 4, 40kDa	0.212
GNAI2	guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2	0.209
S100A14	S100 calcium binding protein A14	0.207
IL12B	interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40)	0.203
IFNG	interferon, gamma	0.198
CCR7	chemokine (C-C motif) receptor 7	0.188
CCL8	chemokine (C-C motif) ligand 8	0.184	Human
TLR2	toll-like receptor 2	0.183
CXCL11	chemokine (C-X-C motif) ligand 11	0.182	Human
CAPG	capping protein (actin filament), gelsolin-like	0.182
FCGR3B	Fc fragment of IgG, low affinity IIIb, receptor (CD16b)	0.169
S100A10	S100 calcium binding protein A10	0.167	Human
CXCL13	chemokine (C-X-C motif) ligand 13	0.141
CXCL5	chemokine (C-X-C motif) ligand 5	0.139	Human
MMP9	matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)	0.137
MMP2	matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)	0.134
TNFAIP6	tumor necrosis factor, alpha-induced protein 6	0.133
FCGR2A	Fc fragment of IgG, low affinity IIa, receptor (CD32)	0.128	Mouse
CCL7	chemokine (C-C motif) ligand 7	0.126	Human
ANXA5	annexin A5	0.117
ARHGDIA	Rho GDP dissociation inhibitor (GDI) alpha	0.109
CD163	CD163 molecule	0.096
ITGA5	integrin, alpha 5 (fibronectin receptor, alpha polypeptide)	0.095
PARD3	par-3 partitioning defective 3 homolog (C. elegans)	0.088
FGR	Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog	0.088
GAS7	growth arrest-specific 7	0.086
IL1R2	interleukin 1 receptor, type II	0.086
AREG	amphiregulin	0.085
CXCL6	chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2)	0.084	Human
TMSB10	thymosin beta 10	0.081
ITGB2	integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)	0.080
SOD2	superoxide dismutase 2, mitochondrial	0.080
C5AR1	complement component 5a receptor 1	0.079	Mouse
EPS8	epidermal growth factor receptor pathway substrate 8	0.079
MSN	moesin	0.077
VAV1	vav 1 guanine nucleotide exchange factor	0.072	Mouse
CD3E	CD3e molecule, epsilon (CD3-TCR complex)	0.072
UBASH3B	ubiquitin associated and SH3 domain containing B	0.070
SELE	selectin E	0.068
CALCOCO2	calcium binding and coiled-coil domain 2	0.066
CCL18	chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated)	0.066	Human Rat
IL10	interleukin 10	0.065
TYROBP	TYRO protein tyrosine kinase binding protein	0.065
SH3BP2	SH3-domain binding protein 2	0.064
S100A12	S100 calcium binding protein A12	0.063	Human
S100P	S100 calcium binding protein P	0.062	Human
LYN	v-yes-1 Yamaguchi sarcoma viral related oncogene homolog	0.061
MYO10	myosin X	0.061
MYH9	myosin, heavy chain 9, non-muscle	0.061
ZYX	zyxin	0.061
SH3BGRL3	SH3 domain binding glutamic acid-rich protein like 3	0.060
JAM2	junctional adhesion molecule 2	0.056	Human
LTA	lymphotoxin alpha (TNF superfamily, member 1)	0.056
BCL2A1	BCL2-related protein A1	0.056
LST1	leukocyte specific transcript 1	0.054
TGIF1	TGFB-induced factor homeobox 1	0.053
PPBP	pro-platelet basic protein (chemokine (C-X-C motif) ligand 7)	0.052	Human
CXCR3	chemokine (C-X-C motif) receptor 3	0.050	Human
TGFBI	transforming growth factor, beta-induced, 68kDa	0.048
CXCR2	chemokine (C-X-C motif) receptor 2	0.048
ANXA1	annexin A1	0.047
HLA-DQB1	major histocompatibility complex, class II, DQ beta 1	0.047
TREM1	triggering receptor expressed on myeloid cells 1	0.047
SELPLG	selectin P ligand	0.044
CCL3	chemokine (C-C motif) ligand 3	0.044
TLR4	toll-like receptor 4	0.044
CCR4	chemokine (C-C motif) receptor 4	0.043	Human
RGS1	regulator of G-protein signaling 1	0.042
TSPO	translocator protein (18kDa)	0.041
RICTOR	RPTOR independent companion of MTOR, complex 2	0.041
RHOC	ras homolog gene family, member C	0.038
VIM	vimentin	0.038
CCL13	chemokine (C-C motif) ligand 13	0.038	Human
MNDA	myeloid cell nuclear differentiation antigen	0.038
SERPINE1	serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1	0.037
CD40LG	CD40 ligand	0.036
IL16	interleukin 16 (lymphocyte chemoattractant factor)	0.036
PF4	platelet factor 4	0.035
AIF1	allograft inflammatory factor 1	0.034
FKBP4	FK506 binding protein 4, 59kDa	0.034
FCN1	ficolin (collagen/fibrinogen domain containing) 1	0.034
ENG	endoglin	0.034
FPR1	formyl peptide receptor 1	0.034
TLN1	talin 1	0.033
NR4A3	nuclear receptor subfamily 4, group A, member 3	0.032
GPR65	G protein-coupled receptor 65	0.031
ITGAM	integrin, alpha M (complement component 3 receptor 3 subunit)	0.031	Mouse
PLAU	plasminogen activator, urokinase	0.031
WIPI1	WD repeat domain, phosphoinositide interacting 1	0.031
MAP4K1	mitogen-activated protein kinase kinase kinase kinase 1	0.030
CCL11	chemokine (C-C motif) ligand 11	0.030	Human
IL10RA	interleukin 10 receptor, alpha	0.030
EZR	ezrin	0.030
FCGR2C	Fc fragment of IgG, low affinity IIc, receptor for (CD32) (gene/pseudogene)	0.030
JAM3	junctional adhesion molecule 3	0.030
ERBB3	v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)	0.030
CD44	CD44 molecule (Indian blood group)	0.029
DUSP10	dual specificity phosphatase 10	0.029
MICA	MHC class I polypeptide-related sequence A	0.029
CH25H	cholesterol 25-hydroxylase	0.028
AHNAK	AHNAK nucleoprotein	0.028
CLIC1	chloride intracellular channel 1	0.028
CCR2	chemokine (C-C motif) receptor 2	0.028	Human
CYBA	cytochrome b-245, alpha polypeptide	0.027
CD86	CD86 molecule	0.027
LAT	linker for activation of T cells	0.027
CD83	CD83 molecule	0.027
S100A2	S100 calcium binding protein A2	0.026	Human
AQP9	aquaporin 9	0.026
PI3	peptidase inhibitor 3, skin-derived	0.026
LMNA	lamin A/C	0.026
SLAMF7	SLAM family member 7	0.026
TAGLN2	transgelin 2	0.026
HLA-DPA1	major histocompatibility complex, class II, DP alpha 1	0.026
SIGLEC1	sialic acid binding Ig-like lectin 1, sialoadhesin	0.026
HCK	hemopoietic cell kinase	0.025
FGL2	fibrinogen-like 2	0.025
FHL2	four and a half LIM domains 2	0.025
IL1RN	interleukin 1 receptor antagonist	0.025
CD74	CD74 molecule, major histocompatibility complex, class II invariant chain	0.025	Mouse
SHC1	SHC (Src homology 2 domain containing) transforming protein 1	0.025
ILK	integrin-linked kinase	0.024
IRF4	interferon regulatory factor 4	0.024
AOAH	acyloxyacyl hydrolase (neutrophil)	0.024
ANGPTL4	angiopoietin-like 4	0.024
BLNK	B-cell linker	0.024
IL2RG	interleukin 2 receptor, gamma	0.024
PLCG1	phospholipase C, gamma 1	0.024
ITGAV	integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51)	0.023
MEST	mesoderm specific transcript homolog (mouse)	0.023
GOPC	golgi-associated PDZ and coiled-coil motif containing	0.023
MS4A6A	membrane-spanning 4-domains, subfamily A, member 6A	0.022
THBD	thrombomodulin	0.022
CLEC10A	C-type lectin domain family 10, member A	0.021
RNASE2	ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin)	0.021
CYBB	cytochrome b-245, beta polypeptide	0.021
SH2B3	SH2B adaptor protein 3	0.021
CA12	carbonic anhydrase XII	0.021
PLA2G7	phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)	0.021
LGALS3	lectin, galactoside-binding, soluble, 3	0.021
IDO1	indoleamine 2,3-dioxygenase 1	0.021
JUP	junction plakoglobin	0.021
LAIR1	leukocyte-associated immunoglobulin-like receptor 1	0.021
F13A1	coagulation factor XIII, A1 polypeptide	0.021
SASH3	SAM and SH3 domain containing 3	0.020
IDE	insulin-degrading enzyme	0.020
CSF2RA	colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage)	0.020
PLP2	proteolipid protein 2 (colonic epithelium-enriched)	0.019	Human
MS4A4A	membrane-spanning 4-domains, subfamily A, member 4	0.019
IL7R	interleukin 7 receptor	0.019
INHBA	inhibin, beta A	0.019
SAMHD1	SAM domain and HD domain 1	0.019
RNASE6	ribonuclease, RNase A family, k6	0.018
LILRA2	leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 2	0.018
TNFSF8	tumor necrosis factor (ligand) superfamily, member 8	0.018
FYB	FYN binding protein	0.018
RHOA	ras homolog gene family, member A	0.018
CD69	CD69 molecule	0.018
GPR109B	G protein-coupled receptor 109B	0.018
EDN1	endothelin 1	0.018	Human Rat
CCR3	chemokine (C-C motif) receptor 3	0.018	Human
VCAN	versican	0.017
UBE2R2	ubiquitin-conjugating enzyme E2R 2	0.017
CHI3L1	chitinase 3-like 1 (cartilage glycoprotein-39)	0.017
CLEC7A	C-type lectin domain family 7, member A	0.017
IGSF6	immunoglobulin superfamily, member 6	0.017
CDC42EP3	CDC42 effector protein (Rho GTPase binding) 3	0.017
FPR2	formyl peptide receptor 2	0.017
AGER	advanced glycosylation end product-specific receptor	0.017
DARC	Duffy blood group, chemokine receptor	0.017
FCER2	Fc fragment of IgE, low affinity II, receptor for (CD23)	0.017
TGFB1	transforming growth factor, beta 1	0.017
BTK	Bruton agammaglobulinemia tyrosine kinase	0.017
FXYD5	FXYD domain containing ion transport regulator 5	0.016
PDZK1	PDZ domain containing 1	0.016
LILRB3	leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3	0.016
ITGAX	integrin, alpha X (complement component 3 receptor 4 subunit)	0.016
CD28	CD28 molecule	0.016
IRAK4	interleukin-1 receptor-associated kinase 4	0.016
LTB	lymphotoxin beta (TNF superfamily, member 3)	0.016
CCR6	chemokine (C-C motif) receptor 6	0.016	Human
TNF	tumor necrosis factor	0.016
TFEC	transcription factor EC	0.016
CD93	CD93 molecule	0.016
UBD	ubiquitin D	0.015
COL6A3	collagen, type VI, alpha 3	0.015
ITGB3	integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)	0.015
NLRP3	NLR family, pyrin domain containing 3	0.015
IL18RAP	interleukin 18 receptor accessory protein	0.015
GYPC	glycophorin C (Gerbich blood group)	0.015
SRGN	serglycin	0.015
CLC	Charcot-Leyden crystal protein	0.015
LTBP2	latent transforming growth factor beta binding protein 2	0.015
EMP1	epithelial membrane protein 1	0.014
CCL21	chemokine (C-C motif) ligand 21	0.014
OLR1	oxidized low density lipoprotein (lectin-like) receptor 1	0.014
PECAM1	platelet/endothelial cell adhesion molecule	0.014
CAP1	CAP, adenylate cyclase-associated protein 1 (yeast)	0.014
GZMK	granzyme K (granzyme 3; tryptase II)	0.014
ARRB2	arrestin, beta 2	0.014
CD300A	CD300a molecule	0.014
C1QA	complement component 1, q subcomponent, A chain	0.014
NKG7	natural killer cell group 7 sequence	0.014
ENTPD1	ectonucleoside triphosphate diphosphohydrolase 1	0.014
IL21R	interleukin 21 receptor	0.013
SLC11A1	solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1	0.013
GZMB	granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)	0.013
EMR1	egf-like module containing, mucin-like, hormone receptor-like 1	0.013
CXCR1	chemokine (C-X-C motif) receptor 1	0.013	Human Rat
JAK1	Janus kinase 1	0.013
VSIG4	V-set and immunoglobulin domain containing 4	0.013
IER3	immediate early response 3	0.013
SPARC	secreted protein, acidic, cysteine-rich (osteonectin)	0.013
FLNB	filamin B, beta	0.013
TIMP2	TIMP metallopeptidase inhibitor 2	0.013
C3AR1	complement component 3a receptor 1	0.013	Mouse
SLC2A3	solute carrier family 2 (facilitated glucose transporter), member 3	0.012
GIMAP4	GTPase, IMAP family member 4	0.012
CLEC4E	C-type lectin domain family 4, member E	0.012
CXCR5	chemokine (C-X-C motif) receptor 5	0.012	Human
TM4SF1	transmembrane 4 L six family member 1	0.012
MYLK	myosin light chain kinase	0.012
MMP12	matrix metallopeptidase 12 (macrophage elastase)	0.012
SLAMF8	SLAM family member 8	0.012
PXN	paxillin	0.012
BIN2	bridging integrator 2	0.012
CYTIP	cytohesin 1 interacting protein	0.012
GPR84	G protein-coupled receptor 84	0.012
CD9	CD9 molecule	0.012
C2	complement component 2	0.012
OSMR	oncostatin M receptor	0.012
LILRB2	leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2	0.012
NFKBIZ	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta	0.012
INPP5D	inositol polyphosphate-5-phosphatase, 145kDa	0.012
LIF	leukemia inhibitory factor (cholinergic differentiation factor)	0.012
PHLDA1	pleckstrin homology-like domain, family A, member 1	0.012
CLEC5A	C-type lectin domain family 5, member A	0.012
GAB2	GRB2-associated binding protein 2	0.012
SERPINB2	serpin peptidase inhibitor, clade B (ovalbumin), member 2	0.012
C1QC	complement component 1, q subcomponent, C chain	0.011
HIPK2	homeodomain interacting protein kinase 2	0.011
LYZ	lysozyme	0.011
TNFRSF1B	tumor necrosis factor receptor superfamily, member 1B	0.011
IQGAP1	IQ motif containing GTPase activating protein 1	0.011
CD99	CD99 molecule	0.011
CSTA	cystatin A (stefin A)	0.011
HLA-DQA1	major histocompatibility complex, class II, DQ alpha 1	0.011
ARHGAP15	Rho GTPase activating protein 15	0.011
ACTN1	actinin, alpha 1	0.011
CCL3L3	chemokine (C-C motif) ligand 3-like 3	0.011
COL1A2	collagen, type I, alpha 2	0.011
TPM4	tropomyosin 4	0.011
GNA15	guanine nucleotide binding protein (G protein), alpha 15 (Gq class)	0.011
SERPINA1	serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1	0.011
CBL	Cas-Br-M (murine) ecotropic retroviral transforming sequence	0.011
SPP1	secreted phosphoprotein 1	0.011
G0S2	G0/G1switch 2	0.011
STC1	stanniocalcin 1	0.011
TGM2	transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase)	0.011
S100A7	S100 calcium binding protein A7	0.011
PRRX1	paired related homeobox 1	0.011
ITGA4	integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)	0.010
ACTB	actin, beta	0.010
RRAS	related RAS viral (r-ras) oncogene homolog	0.010
PTGIS	prostaglandin I2 (prostacyclin) synthase	0.010
LGALS2	lectin, galactoside-binding, soluble, 2	0.010
CAMP	cathelicidin antimicrobial peptide	0.010
IL1F5	interleukin 1 family, member 5 (delta)	0.010
PTX3	pentraxin 3, long	0.010
CLEC4A	C-type lectin domain family 4, member A	0.010
EFNA1	ephrin-A1	0.010
CD53	CD53 molecule	0.010