IMP
Process View
interleukin 1 secretion
The regulated release of interleukin-1 from a cell. Interleukin 1 is produced mainly by activated macrophages; it stimulates thymocyte proliferation by inducing interleukin 2 release and it is involved in the inflammatory response.
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Click on a gene's description to view its network relationships with genes known to be involved in "interleukin 1 secretion"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| CASP1 | caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase) | 0.988 | Mouse Rat | |
| NLRC4 | NLR family, CARD domain containing 4 | 0.978 | ||
| S100A16 | S100 calcium binding protein A16 | 0.646 | ||
| PYCARD | PYD and CARD domain containing | 0.645 | ||
| RIPK2 | receptor-interacting serine-threonine kinase 2 | 0.614 | ||
| ANXA2 | annexin A2 | 0.594 | ||
| SNTB2 | syntrophin, beta 2 (dystrophin-associated protein A1, 59kDa, basic component 2) | 0.552 | ||
| S100A11 | S100 calcium binding protein A11 | 0.508 | Human | |
| S100A6 | S100 calcium binding protein A6 | 0.436 | Human | |
| HP | haptoglobin | 0.325 | ||
| APOC1 | apolipoprotein C-I | 0.275 | ||
| IKBKB | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta | 0.259 | ||
| S100A10 | S100 calcium binding protein A10 | 0.238 | Human | |
| AXL | AXL receptor tyrosine kinase | 0.192 | ||
| TMSB10 | thymosin beta 10 | 0.172 | ||
| AREG | amphiregulin | 0.161 | ||
| PLP2 | proteolipid protein 2 (colonic epithelium-enriched) | 0.151 | ||
| FZD1 | frizzled homolog 1 (Drosophila) | 0.132 | ||
| ANXA1 | annexin A1 | 0.124 | ||
| CASP4 | caspase 4, apoptosis-related cysteine peptidase | 0.124 | Mouse | |
| APOC3 | apolipoprotein C-III | 0.105 | ||
| FKBP4 | FK506 binding protein 4, 59kDa | 0.102 | ||
| A2M | alpha-2-macroglobulin | 0.098 | ||
| MDM2 | Mdm2 p53 binding protein homolog (mouse) | 0.096 | ||
| S100B | S100 calcium binding protein B | 0.094 | ||
| MVP | major vault protein | 0.090 | ||
| CAPG | capping protein (actin filament), gelsolin-like | 0.085 | ||
| CAV2 | caveolin 2 | 0.080 | ||
| IDE | insulin-degrading enzyme | 0.077 | ||
| LGALS3 | lectin, galactoside-binding, soluble, 3 | 0.073 | ||
| LGALS1 | lectin, galactoside-binding, soluble, 1 | 0.063 | ||
| MEFV | Mediterranean fever | 0.063 | ||
| LCAT | lecithin-cholesterol acyltransferase | 0.048 | ||
| PYDC2 | pyrin domain containing 2 | 0.047 | ||
| S100A1 | S100 calcium binding protein A1 | 0.037 | ||
| LRP6 | low density lipoprotein receptor-related protein 6 | 0.036 | ||
| APOA2 | apolipoprotein A-II | 0.033 | ||
| IFI16 | interferon, gamma-inducible protein 16 | 0.029 | Human | |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | 0.028 | ||
| TRIM22 | tripartite motif containing 22 | 0.027 | ||
| LMNA | lamin A/C | 0.027 | ||
| CLEC2B | C-type lectin domain family 2, member B | 0.027 | ||
| S100A4 | S100 calcium binding protein A4 | 0.027 | Human | |
| ALB | albumin | 0.024 | ||
| INADL | InaD-like (Drosophila) | 0.024 | ||
| MS4A1 | membrane-spanning 4-domains, subfamily A, member 1 | 0.024 | ||
| MDM4 | Mdm4 p53 binding protein homolog (mouse) | 0.023 | ||
| ELF4 | E74-like factor 4 (ets domain transcription factor) | 0.023 | ||
| GBP5 | guanylate binding protein 5 | 0.021 | ||
| TIMP1 | TIMP metallopeptidase inhibitor 1 | 0.021 | ||
| IL18 | interleukin 18 (interferon-gamma-inducing factor) | 0.020 | ||
| CLIC1 | chloride intracellular channel 1 | 0.020 | ||
| CARD16 | caspase recruitment domain family, member 16 | 0.020 | ||
| PRKCDBP | protein kinase C, delta binding protein | 0.019 | ||
| EMP3 | epithelial membrane protein 3 | 0.019 | ||
| TSPO | translocator protein (18kDa) | 0.019 | ||
| HCP5 | HLA complex P5 | 0.019 | ||
| TNFRSF10C | tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain | 0.017 | ||
| PPM1D | protein phosphatase, Mg2+/Mn2+ dependent, 1D | 0.017 | ||
| STX12 | syntaxin 12 | 0.017 | ||
| BTN3A2 | butyrophilin, subfamily 3, member A2 | 0.016 | ||
| CSTB | cystatin B (stefin B) | 0.016 | ||
| CCL19 | chemokine (C-C motif) ligand 19 | 0.016 | Mouse | |
| TXNDC2 | thioredoxin domain containing 2 (spermatozoa) | 0.016 | ||
| EMP1 | epithelial membrane protein 1 | 0.016 | ||
| CCR7 | chemokine (C-C motif) receptor 7 | 0.015 | Mouse | |
| GORAB | golgin, RAB6-interacting | 0.015 | ||
| ANXA5 | annexin A5 | 0.014 | ||
| RRAS | related RAS viral (r-ras) oncogene homolog | 0.014 | ||
| APOC2 | apolipoprotein C-II | 0.014 | ||
| IRF8 | interferon regulatory factor 8 | 0.013 | ||
| FLOT1 | flotillin 1 | 0.013 | ||
| TNFSF13B | tumor necrosis factor (ligand) superfamily, member 13b | 0.013 | ||
| TAGLN2 | transgelin 2 | 0.013 | ||
| AHNAK | AHNAK nucleoprotein | 0.013 | ||
| FGA | fibrinogen alpha chain | 0.012 | ||
| CXCL9 | chemokine (C-X-C motif) ligand 9 | 0.012 | ||
| CARD6 | caspase recruitment domain family, member 6 | 0.012 | ||
| FAM83C | family with sequence similarity 83, member C | 0.012 | ||
| PROCR | protein C receptor, endothelial | 0.011 | ||
| BTN3A1 | butyrophilin, subfamily 3, member A1 | 0.011 | ||
| CDC37 | cell division cycle 37 homolog (S. cerevisiae) | 0.011 | ||
| WHSC1L1 | Wolf-Hirschhorn syndrome candidate 1-like 1 | 0.011 | ||
| SELL | selectin L | 0.011 | ||
| PTPN5 | protein tyrosine phosphatase, non-receptor type 5 (striatum-enriched) | 0.011 | ||
| ANG | angiogenin, ribonuclease, RNase A family, 5 | 0.010 | ||
| LY96 | lymphocyte antigen 96 | 0.010 | ||
| HIPK2 | homeodomain interacting protein kinase 2 | 0.010 |