Mus musculus

79 known processes

Rag2

recombination activating gene 2

(Aliases: Rag-2)

Rag2 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
v d j recombination GO:0033151 14 0.996
somatic diversification of immune receptors GO:0002200 53 0.989
leukocyte differentiation GO:0002521 342 0.987
somatic cell dna recombination GO:0016444 51 0.981
positive regulation of regulatory t cell differentiation GO:0045591 4 0.974
positive regulation of isotype switching to igg isotypes GO:0048304 7 0.971
t cell differentiation in thymus GO:0033077 77 0.968
b cell differentiation GO:0030183 78 0.963
regulation of b cell differentiation GO:0045577 23 0.962
positive regulation of gamma delta t cell differentiation GO:0045588 6 0.930
b cell activation GO:0042113 161 0.920
cellular ketone metabolic process GO:0042180 84 0.891
positive regulation of b cell activation GO:0050871 49 0.873
regulation of isotype switching to igg isotypes GO:0048302 10 0.841
immunoglobulin production GO:0002377 73 0.838
lymphocyte proliferation GO:0046651 164 0.830
cd4 positive cd25 positive alpha beta regulatory t cell differentiation GO:0002361 4 0.825
somatic recombination of immunoglobulin gene segments GO:0016447 42 0.806
amine metabolic process GO:0009308 45 0.779
t cell differentiation GO:0030217 174 0.769
lymphocyte differentiation GO:0030098 242 0.766
pre b cell differentiation GO:0002329 7 0.755
lymphocyte homeostasis GO:0002260 64 0.746
regulation of cellular ketone metabolic process GO:0010565 66 0.720
production of molecular mediator of immune response GO:0002440 103 0.718
somatic recombination of immunoglobulin genes involved in immune response GO:0002204 36 0.698
lymphocyte mediated immunity GO:0002449 139 0.694
t cell proliferation GO:0042098 120 0.663
immunoglobulin secretion GO:0048305 17 0.651
positive regulation of cytokine production GO:0001819 174 0.637
dna recombination GO:0006310 92 0.636
somatic diversification of immunoglobulins GO:0016445 43 0.610
defense response to bacterium GO:0042742 119 0.608
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.593
adaptive immune response GO:0002250 155 0.587
regulation of cell activation GO:0050865 289 0.563
positive regulation of adaptive immune response GO:0002821 61 0.559
integrin mediated signaling pathway GO:0007229 27 0.556
cellular amine metabolic process GO:0044106 44 0.549
endodermal cell fate specification GO:0001714 4 0.525
leukocyte proliferation GO:0070661 172 0.509
regulation of peptidase activity GO:0052547 96 0.496
immature b cell differentiation GO:0002327 10 0.479
somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 51 0.469
t cell activation GO:0042110 289 0.458
somatic diversification of immunoglobulins involved in immune response GO:0002208 36 0.448
regulation of cellular amine metabolic process GO:0033238 20 0.430
positive regulation of granulocyte macrophage colony stimulating factor biosynthetic process GO:0045425 2 0.413
serotonin secretion involved in inflammatory response GO:0002442 4 0.412
immunoglobulin production involved in immunoglobulin mediated immune response GO:0002381 43 0.381
thymocyte apoptotic process GO:0070242 19 0.379
positive regulation of antimicrobial peptide biosynthetic process GO:0002807 1 0.378
negative regulation of interleukin 2 biosynthetic process GO:0045085 3 0.372
neutrophil activation GO:0042119 9 0.356
immune response activating signal transduction GO:0002757 116 0.343
positive regulation of mapk cascade GO:0043410 170 0.340
fc epsilon receptor signaling pathway GO:0038095 3 0.338
alpha beta t cell differentiation GO:0046632 69 0.338
regulation of t cell differentiation GO:0045580 83 0.337
regulation of alpha beta t cell differentiation GO:0046637 35 0.330
cell activation involved in immune response GO:0002263 126 0.316
regulation of lymphocyte differentiation GO:0045619 107 0.313
negative regulation of creb transcription factor activity GO:0032792 2 0.307
negative regulation of inflammatory response to antigenic stimulus GO:0002862 10 0.306
regulation of platelet activation GO:0010543 17 0.302
isotype switching to igg isotypes GO:0048291 10 0.300
homeostasis of number of cells GO:0048872 210 0.292
negative regulation of t cell mediated cytotoxicity GO:0001915 3 0.291
metanephric dct cell differentiation GO:0072240 3 0.285
regulation of cysteine type endopeptidase activity GO:2000116 65 0.281
immunoglobulin mediated immune response GO:0016064 69 0.276
regulation of epithelial cell proliferation GO:0050678 141 0.271
leukocyte apoptotic process GO:0071887 71 0.254
leukocyte homeostasis GO:0001776 79 0.248
cytokine production GO:0001816 319 0.247
regulation of ion transport GO:0043269 215 0.245
defense response to virus GO:0051607 68 0.243
modulation by virus of host process GO:0019054 2 0.241
positive regulation of leukocyte proliferation GO:0070665 73 0.240
negative regulation of interleukin 5 production GO:0032714 4 0.239
positive regulation of map kinase activity GO:0043406 84 0.234
regulation of cellular amino acid metabolic process GO:0006521 5 0.233
t cell apoptotic process GO:0070231 39 0.232
t cell receptor signaling pathway GO:0050852 46 0.228
regulation of toll like receptor 2 signaling pathway GO:0034135 3 0.218
positive regulation of stress activated mapk cascade GO:0032874 48 0.217
positive regulation of lymphocyte activation GO:0051251 140 0.215
nuclear division GO:0000280 158 0.213
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 68 0.213
regulation of endopeptidase activity GO:0052548 89 0.207
negative regulation of t cell cytokine production GO:0002725 1 0.199
regulation of b cell mediated immunity GO:0002712 37 0.199
chromatin modification GO:0016568 187 0.193
neuroblast fate determination GO:0007400 1 0.193
response to inorganic substance GO:0010035 96 0.188
skeletal muscle organ development GO:0060538 163 0.185
regulation of lymphocyte proliferation GO:0050670 117 0.179
thymus development GO:0048538 41 0.176
regulation of toll like receptor 4 signaling pathway GO:0034143 4 0.174
cell adhesion GO:0007155 329 0.172
positive regulation of type iii hypersensitivity GO:0001805 3 0.172
regulation of regulatory t cell differentiation GO:0045589 7 0.172
lymphocyte activation involved in immune response GO:0002285 93 0.164
positive regulation of activation of membrane attack complex GO:0001970 2 0.164
monocarboxylic acid transport GO:0015718 44 0.164
paramesonephric duct development GO:0061205 3 0.164
positive regulation of t cell differentiation GO:0045582 52 0.163
positive regulation of jun kinase activity GO:0043507 30 0.163
positive regulation of alpha beta t cell differentiation GO:0046638 28 0.161
negative regulation of t cell apoptotic process GO:0070233 18 0.159
regulation of blood vessel endothelial cell migration GO:0043535 12 0.159
regulation of muscle tissue development GO:1901861 97 0.156
regulation of b cell activation GO:0050864 81 0.156
protein modification by small protein conjugation GO:0032446 187 0.156
regulation of protein localization GO:0032880 231 0.156
platelet degranulation GO:0002576 6 0.154
regulation of isotype switching GO:0045191 22 0.153
serotonin production involved in inflammatory response GO:0002351 4 0.152
tissue remodeling GO:0048771 102 0.149
protein maturation GO:0051604 176 0.148
negative regulation of adaptive immune response GO:0002820 25 0.146
fertilization GO:0009566 127 0.146
b cell receptor signaling pathway GO:0050853 20 0.143
myeloid cell homeostasis GO:0002262 114 0.143
neutrophil degranulation GO:0043312 6 0.141
positive regulation of b cell mediated immunity GO:0002714 26 0.137
cellular response to organonitrogen compound GO:0071417 145 0.135
morphogenesis of a branching epithelium GO:0061138 193 0.135
positive regulation of protein kinase activity GO:0045860 144 0.135
b cell mediated immunity GO:0019724 71 0.133
regulation of cytokine biosynthetic process GO:0042035 59 0.133
defense response to other organism GO:0098542 197 0.131
branching involved in mammary gland duct morphogenesis GO:0060444 27 0.130
regulation of antimicrobial humoral response GO:0002759 3 0.130
positive regulation of production of molecular mediator of immune response GO:0002702 45 0.127
positive regulation of t cell activation GO:0050870 101 0.127
cellular response to biotic stimulus GO:0071216 92 0.127
cellular response to lipid GO:0071396 145 0.126
response to organic cyclic compound GO:0014070 198 0.126
leukocyte mediated immunity GO:0002443 174 0.126
negative regulation of b cell mediated immunity GO:0002713 7 0.123
protein processing GO:0016485 163 0.122
chromatin organization GO:0006325 206 0.119
lipid localization GO:0010876 126 0.119
positive regulation of leukocyte apoptotic process GO:2000108 21 0.119
regulation of protein processing GO:0070613 96 0.117
response to retinoic acid GO:0032526 56 0.117
immune response regulating signaling pathway GO:0002764 125 0.117
positive regulation of mitotic cell cycle GO:0045931 41 0.116
regulation of immunoglobulin mediated immune response GO:0002889 37 0.116
regulation of protein maturation GO:1903317 96 0.115
regulation of vitamin metabolic process GO:0030656 3 0.112
neutrophil mediated immunity GO:0002446 19 0.112
dna metabolic process GO:0006259 303 0.112
antibacterial peptide production GO:0002778 2 0.111
t cell receptor v d j recombination GO:0033153 5 0.108
response to acid chemical GO:0001101 111 0.108
regulation of anion transport GO:0044070 27 0.107
regulation of lymphocyte activation GO:0051249 240 0.106
carboxylic acid transport GO:0046942 100 0.106
maintenance of epithelial cell apical basal polarity GO:0045199 2 0.105
regulation of t cell activation GO:0050863 170 0.103
positive regulation of secretion by cell GO:1903532 114 0.103
regulation of cytokine production GO:0001817 266 0.102
positive regulation of angiogenesis GO:0045766 46 0.102
neutrophil apoptotic process GO:0001781 3 0.101
immune effector process GO:0002252 321 0.100
positive regulation of isotype switching GO:0045830 15 0.099
positive regulation of endothelial cell migration GO:0010595 12 0.099
positive regulation of dna recombination GO:0045911 17 0.098
innate immune response activating signal transduction GO:0002758 50 0.098
positive regulation of b cell differentiation GO:0045579 13 0.097
positive regulation of cellular amine metabolic process GO:0033240 5 0.096
negative regulation of chronic inflammatory response GO:0002677 3 0.095
regulation of hydrolase activity GO:0051336 246 0.095
fibroblast growth factor production GO:0090269 4 0.095
lymphocyte apoptotic process GO:0070227 54 0.094
negative regulation of lymphocyte apoptotic process GO:0070229 24 0.093
regulation of t cell apoptotic process GO:0070232 28 0.092
negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 23 0.092
regulation of cell migration involved in sprouting angiogenesis GO:0090049 4 0.091
regulation of osteoblast differentiation GO:0045667 67 0.090
mrna transcription from rna polymerase ii promoter GO:0042789 4 0.088
establishment or maintenance of apical basal cell polarity GO:0035088 21 0.088
interleukin 6 production GO:0032635 58 0.087
positive regulation of cell activation GO:0050867 158 0.086
immune response activating cell surface receptor signaling pathway GO:0002429 72 0.086
response to organonitrogen compound GO:0010243 246 0.086
leukocyte activation involved in immune response GO:0002366 126 0.085
positive regulation of antimicrobial humoral response GO:0002760 2 0.084
axon guidance GO:0007411 141 0.084
regulation of lipid metabolic process GO:0019216 118 0.083
positive regulation of cytokine secretion GO:0050715 41 0.083
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.082
regulation of cd4 positive alpha beta t cell differentiation GO:0043370 21 0.082
positive regulation of antibacterial peptide biosynthetic process GO:0006963 1 0.081
negative regulation of protein metabolic process GO:0051248 282 0.081
positive regulation of protein transport GO:0051222 93 0.079
positive regulation of epithelial cell proliferation involved in lung morphogenesis GO:0060501 3 0.079
regulation of body fluid levels GO:0050878 162 0.079
visceral motor neuron differentiation GO:0021524 3 0.079
positive regulation of granulocyte macrophage colony stimulating factor production GO:0032725 3 0.079
anion transport GO:0006820 177 0.078
regulation of multi organism process GO:0043900 111 0.078
cell type specific apoptotic process GO:0097285 268 0.078
regulation of type iii hypersensitivity GO:0001803 3 0.077
intracellular receptor signaling pathway GO:0030522 74 0.077
regulation of jun kinase activity GO:0043506 40 0.077
epidermis development GO:0008544 187 0.077
gland development GO:0048732 330 0.076
regulation of interferon gamma production GO:0032649 57 0.075
antibacterial humoral response GO:0019731 8 0.074
stem cell development GO:0048864 219 0.073
maintenance of apical basal cell polarity GO:0035090 3 0.073
negative regulation of cellular amine metabolic process GO:0033239 1 0.072
regulation of secretion by cell GO:1903530 249 0.072
covalent chromatin modification GO:0016569 163 0.072
immunoglobulin v d j recombination GO:0033152 5 0.072
developmental maturation GO:0021700 193 0.071
circadian rhythm GO:0007623 114 0.071
response to lipopolysaccharide GO:0032496 128 0.070
cellular amino acid metabolic process GO:0006520 103 0.068
stem cell maintenance GO:0019827 130 0.068
response to hydrogen peroxide GO:0042542 32 0.068
positive regulation of lymphocyte differentiation GO:0045621 61 0.068
negative regulation of protein processing GO:0010955 79 0.068
regulation of tissue remodeling GO:0034103 38 0.068
antimicrobial peptide production GO:0002775 2 0.067
positive regulation of jnk cascade GO:0046330 46 0.067
positive regulation of b cell proliferation GO:0030890 24 0.067
regulation of lymphocyte apoptotic process GO:0070228 41 0.065
activation of immune response GO:0002253 138 0.065
regulation of corticotropin releasing hormone secretion GO:0043397 2 0.065
regulation of leukocyte differentiation GO:1902105 159 0.064
regulation of proteolysis GO:0030162 164 0.064
fatty acid transport GO:0015908 28 0.064
small molecule catabolic process GO:0044282 71 0.064
regulation of t cell proliferation GO:0042129 92 0.064
regulation of antimicrobial peptide production GO:0002784 1 0.062
muscle cell development GO:0055001 133 0.062
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.061
myoblast differentiation GO:0045445 52 0.061
calcium mediated signaling GO:0019722 46 0.061
positive regulation of translational initiation GO:0045948 4 0.061
negative regulation of molecular function GO:0044092 258 0.060
anatomical structure homeostasis GO:0060249 145 0.060
inflammatory response GO:0006954 244 0.060
protein acylation GO:0043543 64 0.060
regulation of thymocyte apoptotic process GO:0070243 14 0.059
negative regulation of peptidase activity GO:0010466 46 0.058
positive regulation of cell migration involved in sprouting angiogenesis GO:0090050 3 0.057
regulation of myotube differentiation GO:0010830 62 0.057
antimicrobial peptide biosynthetic process GO:0002777 2 0.057
positive regulation of blood vessel endothelial cell migration GO:0043536 5 0.057
negative regulation of thymocyte apoptotic process GO:0070244 8 0.056
regulation of production of molecular mediator of immune response GO:0002700 65 0.055
regulation of map kinase activity GO:0043405 120 0.055
regulation of protein serine threonine kinase activity GO:0071900 157 0.055
regulation of endothelial cell migration GO:0010594 22 0.054
negative regulation of cell proliferation GO:0008285 296 0.054
regulation of immunoglobulin production GO:0002637 42 0.054
positive regulation of interleukin 1 secretion GO:0050716 14 0.053
positive regulation of complement activation GO:0045917 2 0.053
neuroblast differentiation GO:0014016 2 0.053
positive regulation of immunoglobulin mediated immune response GO:0002891 26 0.053
serotonin secretion by platelet GO:0002554 3 0.052
t cell homeostasis GO:0043029 35 0.052
positive regulation of secretion GO:0051047 130 0.052
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 62 0.052
gamma delta t cell differentiation GO:0042492 11 0.052
cell killing GO:0001906 67 0.052
t cell mediated immunity GO:0002456 50 0.051
tongue morphogenesis GO:0043587 8 0.051
negative regulation of cytokine production GO:0001818 84 0.051
positive regulation of immunoglobulin production GO:0002639 28 0.051
small molecule biosynthetic process GO:0044283 132 0.051
forebrain neuron differentiation GO:0021879 52 0.050
viral process GO:0016032 41 0.049
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.049
positive regulation of immune effector process GO:0002699 107 0.049
regulation of nuclear division GO:0051783 56 0.048
tyrosine phosphorylation of stat5 protein GO:0042506 9 0.048
positive regulation of chronic inflammatory response GO:0002678 4 0.047
engulfment of apoptotic cell GO:0043652 3 0.047
positive regulation of cytokine biosynthetic process GO:0042108 40 0.047
angiogenesis GO:0001525 201 0.047
regulation of axon diameter GO:0031133 6 0.047
negative regulation of endopeptidase activity GO:0010951 44 0.046
spinal cord development GO:0021510 81 0.045
cell cell recognition GO:0009988 44 0.045
camera type eye development GO:0043010 266 0.045
regulation of interleukin 10 production GO:0032653 21 0.045
regulation of leukocyte apoptotic process GO:2000106 56 0.045
b cell proliferation GO:0042100 53 0.044
negative regulation of hydrolase activity GO:0051346 71 0.044
positive regulation of proteolysis GO:0045862 85 0.044
striated muscle tissue development GO:0014706 293 0.044
reactive oxygen species metabolic process GO:0072593 84 0.044
positive regulation of cell cycle process GO:0090068 61 0.044
embryonic forelimb morphogenesis GO:0035115 32 0.043
limb development GO:0060173 166 0.043
righting reflex GO:0060013 9 0.043
regulation of response to wounding GO:1903034 189 0.043
epithelial cell migration GO:0010631 63 0.043
tissue migration GO:0090130 68 0.043
compound eye development GO:0048749 1 0.043
negative regulation of interferon gamma biosynthetic process GO:0045077 2 0.042
lipid biosynthetic process GO:0008610 179 0.042
platelet aggregation GO:0070527 20 0.042
organic hydroxy compound metabolic process GO:1901615 203 0.042
positive regulation of leukocyte differentiation GO:1902107 86 0.042
response to oxidative stress GO:0006979 123 0.042
t cell selection GO:0045058 34 0.042
positive regulation of hair cycle GO:0042635 7 0.041
cellular response to nutrient levels GO:0031669 64 0.041
regulation of striated muscle cell differentiation GO:0051153 81 0.041
regulation of dna recombination GO:0000018 34 0.041
cd8 positive alpha beta t cell differentiation involved in immune response GO:0002302 2 0.041
interferon gamma production GO:0032609 67 0.040
nucleic acid phosphodiester bond hydrolysis GO:0090305 49 0.040
regulation of granulocyte macrophage colony stimulating factor biosynthetic process GO:0045423 2 0.040
protein kinase b signaling GO:0043491 74 0.040
negative regulation of multi organism process GO:0043901 68 0.040
negative regulation of blood vessel endothelial cell migration GO:0043537 3 0.040
head morphogenesis GO:0060323 34 0.040
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 87 0.040
face morphogenesis GO:0060325 29 0.040
negative regulation of proteolysis GO:0045861 74 0.039
regulation of jnk cascade GO:0046328 62 0.039
isotype switching to ige isotypes GO:0048289 7 0.039
mesonephric duct development GO:0072177 5 0.039
antigen receptor mediated signaling pathway GO:0050851 64 0.039
symbiosis encompassing mutualism through parasitism GO:0044403 83 0.039
detection of external stimulus GO:0009581 61 0.039
mammary gland epithelium development GO:0061180 65 0.037
steroid metabolic process GO:0008202 119 0.037
amelogenesis GO:0097186 12 0.037
odontogenesis GO:0042476 78 0.036
positive regulation of mitosis GO:0045840 14 0.036
hormone metabolic process GO:0042445 86 0.036
regulation of kinase activity GO:0043549 249 0.036
rna polymerase ii transcriptional preinitiation complex assembly GO:0051123 3 0.036
activation of membrane attack complex GO:0001905 4 0.036
positive regulation of protein kinase b signaling GO:0051897 32 0.035
monoamine transport GO:0015844 33 0.035
positive regulation of cell death GO:0010942 224 0.035
leukocyte mediated cytotoxicity GO:0001909 62 0.035
regulation of tolerance induction dependent upon immune response GO:0002652 1 0.035
endodermal cell differentiation GO:0035987 14 0.035
myotube differentiation GO:0014902 105 0.035
regulation of odontogenesis GO:0042481 18 0.035
positive regulation of cell projection organization GO:0031346 95 0.035
positive regulation of cell cycle GO:0045787 92 0.035
organic anion transport GO:0015711 137 0.034
positive regulation of lymphocyte mediated immunity GO:0002708 62 0.034
positive regulation of exocytosis GO:0045921 20 0.034
neutrophil differentiation GO:0030223 3 0.034
regulation of cell cycle process GO:0010564 160 0.034
single fertilization GO:0007338 82 0.034
regulation of system process GO:0044057 200 0.034
positive regulation of t cell proliferation GO:0042102 52 0.034
regulation of leukocyte mediated immunity GO:0002703 104 0.033
cellular response to starvation GO:0009267 57 0.033
regulation of peptidyl tyrosine phosphorylation GO:0050730 93 0.032
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.032
positive regulation of programmed cell death GO:0043068 218 0.032
cd4 positive or cd8 positive alpha beta t cell lineage commitment GO:0043369 8 0.031
establishment or maintenance of epithelial cell apical basal polarity GO:0045197 14 0.031
t cell homeostatic proliferation GO:0001777 4 0.031
pattern recognition receptor signaling pathway GO:0002221 47 0.031
bone development GO:0060348 120 0.031
somitogenesis GO:0001756 69 0.031
neuroblast fate commitment GO:0014017 1 0.031
nitrogen compound transport GO:0071705 271 0.031
chemotaxis GO:0006935 247 0.031
negative regulation of toll like receptor 2 signaling pathway GO:0034136 3 0.030
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.030
osteoclast proliferation GO:0002158 4 0.030
bone remodeling GO:0046849 53 0.030
response to metal ion GO:0010038 47 0.030
regionalization GO:0003002 337 0.030
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.030
blood vessel morphogenesis GO:0048514 285 0.030
regulation of homeostatic process GO:0032844 182 0.030
striated muscle cell development GO:0055002 125 0.030
positive regulation of glial cell proliferation GO:0060252 4 0.030
negative regulation of histone modification GO:0031057 18 0.030
innate immune response GO:0045087 157 0.029
bone morphogenesis GO:0060349 78 0.029
regulation of interleukin 6 production GO:0032675 55 0.029
positive regulation of rna polymerase ii transcriptional preinitiation complex assembly GO:0045899 2 0.029
positive regulation of lipid metabolic process GO:0045834 40 0.029
regulation of epithelial cell migration GO:0010632 35 0.029
metencephalon development GO:0022037 89 0.029
cellular response to hormone stimulus GO:0032870 150 0.029
organic hydroxy compound transport GO:0015850 93 0.029
regulation of t cell mediated immunity GO:0002709 34 0.029
paraxial mesodermal cell fate commitment GO:0048343 2 0.029
segmentation GO:0035282 93 0.029
appendage development GO:0048736 166 0.029
positive regulation of lymphocyte apoptotic process GO:0070230 13 0.028
nuclear transport GO:0051169 139 0.028
male gamete generation GO:0048232 285 0.028
regulation of action potential GO:0098900 4 0.028
response to peptide GO:1901652 136 0.028
humoral immune response mediated by circulating immunoglobulin GO:0002455 14 0.028
skeletal muscle fiber development GO:0048741 58 0.028
trophectodermal cell differentiation GO:0001829 21 0.028
positive t cell selection GO:0043368 23 0.028
regulation of testosterone biosynthetic process GO:2000224 2 0.027
protein activation cascade GO:0072376 19 0.027
regulation of cell cycle GO:0051726 281 0.027
thymic t cell selection GO:0045061 22 0.027
regulation of jak stat cascade GO:0046425 34 0.027
posttranscriptional regulation of gene expression GO:0010608 155 0.027
activation of phospholipase c activity GO:0007202 2 0.027
positive regulation of secondary heart field cardioblast proliferation GO:0072513 4 0.027
reflex GO:0060004 22 0.027
response to radiation GO:0009314 165 0.027
positive regulation of lymphocyte proliferation GO:0050671 70 0.027
cytokine biosynthetic process GO:0042089 68 0.026
long chain fatty acid transport GO:0015909 15 0.026
proprioception GO:0019230 4 0.026
transmission of nerve impulse GO:0019226 76 0.026
cochlea morphogenesis GO:0090103 22 0.026
positive regulation of optic nerve formation GO:2000597 1 0.026
disruption of cells of other organism involved in symbiotic interaction GO:0051818 13 0.026
regulation of interleukin 6 biosynthetic process GO:0045408 11 0.026
positive regulation of protein secretion GO:0050714 52 0.026
response to molecule of bacterial origin GO:0002237 143 0.026
neuron projection regeneration GO:0031102 14 0.026
regulation of t cell differentiation in thymus GO:0033081 24 0.026
carbohydrate homeostasis GO:0033500 128 0.026
regulation of granulocyte macrophage colony stimulating factor production GO:0032645 3 0.026
regulation of heart looping GO:1901207 1 0.025
hypophysis morphogenesis GO:0048850 3 0.025
embryonic skeletal system morphogenesis GO:0048704 91 0.025
epithelium migration GO:0090132 63 0.025
regulation of cellular response to stress GO:0080135 159 0.025
fat soluble vitamin metabolic process GO:0006775 11 0.025
positive regulation of endocardial cushion to mesenchymal transition involved in heart valve formation GO:2000802 1 0.025
alpha beta t cell activation GO:0046631 91 0.025
spinal cord motor neuron differentiation GO:0021522 35 0.025
regulation of bone remodeling GO:0046850 28 0.025
sensory perception of mechanical stimulus GO:0050954 107 0.025
sprouting angiogenesis GO:0002040 26 0.024
regulation of cardiac chamber formation GO:1901210 1 0.024
regulation of mitosis GO:0007088 29 0.024
regulation of fatty acid transport GO:2000191 10 0.024
modulation of programmed cell death in other organism GO:0044531 2 0.024
blood vessel endothelial cell migration GO:0043534 23 0.024
zymogen activation GO:0031638 41 0.024
regulation of neuron differentiation GO:0045664 281 0.024
negative regulation of protein maturation GO:1903318 79 0.024
regulation of superoxide metabolic process GO:0090322 8 0.024
regulation of protein kinase b signaling GO:0051896 56 0.024
interleukin 4 production GO:0032633 24 0.024
metanephric nephron morphogenesis GO:0072273 19 0.023
dct cell differentiation GO:0072069 3 0.023
regulation of mast cell activation GO:0033003 21 0.023
cranial nerve development GO:0021545 41 0.023
cell division GO:0051301 120 0.023
negative regulation of chromatin modification GO:1903309 19 0.023
icosanoid transport GO:0071715 14 0.023
androgen biosynthetic process GO:0006702 4 0.023
cellular lipid metabolic process GO:0044255 323 0.023
natural killer cell activation GO:0030101 44 0.023
mrna transcription GO:0009299 4 0.022
detection of stimulus involved in sensory perception GO:0050906 44 0.022
myeloid leukocyte activation GO:0002274 83 0.022
regulation of mapk cascade GO:0043408 248 0.022
interleukin 3 production GO:0032632 3 0.022
development of primary female sexual characteristics GO:0046545 73 0.022
testosterone biosynthetic process GO:0061370 2 0.022
t cell differentiation involved in immune response GO:0002292 30 0.022
peptidyl serine phosphorylation GO:0018105 74 0.022
positive regulation of cd4 positive alpha beta t cell differentiation GO:0043372 14 0.021
renal system development GO:0072001 225 0.021
regulation of cell division GO:0051302 76 0.021
cellular response to retinoic acid GO:0071300 25 0.021
positive regulation of nuclear division GO:0051785 27 0.021
regulation of leukocyte proliferation GO:0070663 121 0.021

Rag2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.071
acquired metabolic disease DOID:0060158 0 0.071
carbohydrate metabolism disease DOID:0050013 0 0.033
glucose metabolism disease DOID:4194 0 0.033
primary immunodeficiency disease DOID:612 0 0.030
blood protein disease DOID:620 0 0.030
immune system disease DOID:2914 0 0.030
agammaglobulinemia DOID:2583 0 0.030
disease of anatomical entity DOID:7 0 0.030
common variable immunodeficiency DOID:12177 0 0.030
b cell deficiency DOID:2115 0 0.030
hematopoietic system disease DOID:74 0 0.030
diabetes mellitus DOID:9351 0 0.025
bone disease DOID:0080001 0 0.025
musculoskeletal system disease DOID:17 0 0.025
connective tissue disease DOID:65 0 0.025
disease of cellular proliferation DOID:14566 0 0.024