IMP
Process View
negative regulation of interleukin 2 biosynthetic process
Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-2.
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In addition to gene-name show these genes:
Click on a gene's description to view its network relationships with genes known to be involved in "negative regulation of interleukin 2 biosynthetic process"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| Cd19 | CD19 antigen | 0.873 | ||
| Ifng | interferon gamma | 0.742 | ||
| Cd80 | CD80 antigen | 0.679 | ||
| Tcra | T-cell receptor alpha chain | 0.657 | ||
| Pdcd1 | programmed cell death 1 | 0.433 | ||
| Rag1 | recombination activating gene 1 | 0.427 | ||
| Il4 | interleukin 4 | 0.383 | ||
| Rag2 | recombination activating gene 2 | 0.372 | ||
| Foxn1 | forkhead box N1 | 0.312 | ||
| Ikzf1 | IKAROS family zinc finger 1 | 0.286 | ||
| Il2 | interleukin 2 | 0.262 | ||
| Gli2 | GLI-Kruppel family member GLI2 | 0.223 | ||
| Cd28 | CD28 antigen | 0.218 | ||
| Il10 | interleukin 10 | 0.172 | ||
| Tnf | tumor necrosis factor | 0.154 | ||
| Tnfrsf4 | tumor necrosis factor receptor superfamily, member 4 | 0.143 | ||
| Ctla4 | cytotoxic T-lymphocyte-associated protein 4 | 0.133 | ||
| Socs1 | suppressor of cytokine signaling 1 | 0.132 | ||
| Batf | basic leucine zipper transcription factor, ATF-like | 0.089 | ||
| Foxp2 | forkhead box P2 | 0.085 | Mouse | |
| Icos | inducible T-cell co-stimulator | 0.084 | ||
| Card11 | caspase recruitment domain family, member 11 | 0.082 | ||
| Tnfrsf9 | tumor necrosis factor receptor superfamily, member 9 | 0.079 | ||
| Map3k14 | mitogen-activated protein kinase kinase kinase 14 | 0.070 | ||
| Foxp1 | forkhead box P1 | 0.067 | Mouse | |
| Sp110 | Sp110 nuclear body protein | 0.057 | ||
| Lat | linker for activation of T cells | 0.053 | ||
| Prf1 | perforin 1 (pore forming protein) | 0.053 | ||
| Fas | Fas (TNF receptor superfamily member 6) | 0.052 | ||
| Tbx21 | T-box 21 | 0.050 | ||
| Ccr7 | chemokine (C-C motif) receptor 7 | 0.047 | ||
| Cd4 | CD4 antigen | 0.045 | ||
| Smad4 | MAD homolog 4 (Drosophila) | 0.045 | ||
| Ttc7 | tetratricopeptide repeat domain 7 | 0.038 | ||
| Naip6 | NLR family, apoptosis inhibitory protein 6 | 0.038 | ||
| Dicer1 | Dicer1, Dcr-1 homolog (Drosophila) | 0.038 | ||
| Meox2 | mesenchyme homeobox 2 | 0.037 | ||
| Cd5 | CD5 antigen | 0.036 | ||
| Slamf1 | signaling lymphocytic activation molecule family member 1 | 0.034 | ||
| Lag3 | lymphocyte-activation gene 3 | 0.033 | ||
| Batf2 | basic leucine zipper transcription factor, ATF-like 2 | 0.033 | ||
| Fyn | Fyn proto-oncogene | 0.031 | ||
| Trp53 | transformation related protein 53 | 0.031 | ||
| Cxcl9 | chemokine (C-X-C motif) ligand 9 | 0.029 | ||
| Nlrp3 | NLR family, pyrin domain containing 3 | 0.029 | ||
| Rc3h1 | RING CCCH (C3H) domains 1 | 0.027 | ||
| Il12rb1 | interleukin 12 receptor, beta 1 | 0.027 | ||
| Il2rg | interleukin 2 receptor, gamma chain | 0.027 | ||
| Inpp5d | inositol polyphosphate-5-phosphatase D | 0.026 | ||
| Abl1 | c-abl oncogene 1, non-receptor tyrosine kinase | 0.023 | ||
| Cd160 | CD160 antigen | 0.023 | ||
| Il6 | interleukin 6 | 0.022 | ||
| Aire | autoimmune regulator (autoimmune polyendocrinopathy candidiasis ectodermal dystrophy) | 0.022 | ||
| Stat3 | signal transducer and activator of transcription 3 | 0.022 | ||
| Ubd | ubiquitin D | 0.020 | ||
| Cyp11a1 | cytochrome P450, family 11, subfamily a, polypeptide 1 | 0.020 | ||
| Zfp362 | zinc finger protein 362 | 0.019 | ||
| Batf3 | basic leucine zipper transcription factor, ATF-like 3 | 0.019 | ||
| Rgs1 | regulator of G-protein signaling 1 | 0.018 | ||
| Il2rb | interleukin 2 receptor, beta chain | 0.018 | ||
| Ccl4 | chemokine (C-C motif) ligand 4 | 0.017 | ||
| Slamf8 | SLAM family member 8 | 0.017 | ||
| Il21r | interleukin 21 receptor | 0.017 | ||
| Pou5f1 | POU domain, class 5, transcription factor 1 | 0.017 | ||
| Lta | lymphotoxin A | 0.017 | ||
| Hhex | hematopoietically expressed homeobox | 0.016 | ||
| Npm3 | nucleoplasmin 3 | 0.016 | ||
| Plp1 | proteolipid protein (myelin) 1 | 0.016 | ||
| Irf1 | interferon regulatory factor 1 | 0.016 | ||
| Cd247 | CD247 antigen | 0.016 | ||
| H2-Ab1 | histocompatibility 2, class II antigen A, beta 1 | 0.015 | ||
| Cd274 | CD274 antigen | 0.014 | Mouse | |
| Rel | reticuloendotheliosis oncogene | 0.014 | ||
| Stat5a | signal transducer and activator of transcription 5A | 0.014 | ||
| Bach2 | BTB and CNC homology 2 | 0.014 | ||
| Hpgds | hematopoietic prostaglandin D synthase | 0.014 | ||
| Zap70 | zeta-chain (TCR) associated protein kinase | 0.014 | ||
| Il27ra | interleukin 27 receptor, alpha | 0.014 | ||
| Ahr | aryl-hydrocarbon receptor | 0.013 | ||
| Il2ra | interleukin 2 receptor, alpha chain | 0.013 | ||
| Map3k7 | mitogen-activated protein kinase kinase kinase 7 | 0.013 | ||
| Bcl2l11 | BCL2-like 11 (apoptosis facilitator) | 0.012 | ||
| Ctsl | cathepsin L | 0.012 | ||
| Il4ra | interleukin 4 receptor, alpha | 0.012 | ||
| Stat5b | signal transducer and activator of transcription 5B | 0.012 | ||
| Fasl | Fas ligand (TNF superfamily, member 6) | 0.012 | ||
| Slamf7 | SLAM family member 7 | 0.011 | ||
| Plek | pleckstrin | 0.011 | ||
| Jak1 | Janus kinase 1 | 0.011 | ||
| Zbp1 | Z-DNA binding protein 1 | 0.011 | ||
| Smad1 | MAD homolog 1 (Drosophila) | 0.011 | ||
| Dclre1c | DNA cross-link repair 1C, PSO2 homolog (S. cerevisiae) | 0.011 | ||
| Ptprc | protein tyrosine phosphatase, receptor type, C | 0.011 | ||
| Traf1 | TNF receptor-associated factor 1 | 0.010 | ||
| Ccl17 | chemokine (C-C motif) ligand 17 | 0.010 | ||
| Ptpn22 | protein tyrosine phosphatase, non-receptor type 22 (lymphoid) | 0.010 | ||
| Tlr7 | toll-like receptor 7 | 0.010 | ||
| Nfatc2 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 | 0.010 |