IMP

Process View

Mus musculus

10 genes annotated in mouse

Multi-species View

regulation of isotype switching to igg isotypes

GO:0048302

Any process that modulates the frequency, rate or extent of isotype switching to IgG isotypes.

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Known genes in the process in mouse Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "regulation of isotype switching to igg isotypes"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "regulation of isotype switching to igg isotypes" (in gray)

Name	Description	Probability	Func Analog Organism
Ifng	interferon gamma	0.957
Tcra	T-cell receptor alpha chain	0.865
Rag2	recombination activating gene 2	0.841
Tnf	tumor necrosis factor	0.813
Il4	interleukin 4	0.696
Map3k14	mitogen-activated protein kinase kinase kinase 14	0.556
Cd28	CD28 antigen	0.518
Cd19	CD19 antigen	0.452
Nfkb2	nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100	0.424
Fyn	Fyn proto-oncogene	0.385
Foxp3	forkhead box P3	0.376
Il10	interleukin 10	0.240
Ikzf1	IKAROS family zinc finger 1	0.230
Igh	immunoglobulin heavy chain complex	0.208
Lta	lymphotoxin A	0.196
Fas	Fas (TNF receptor superfamily member 6)	0.191
Tnfrsf1a	tumor necrosis factor receptor superfamily, member 1a	0.188
Socs1	suppressor of cytokine signaling 1	0.157
Il6	interleukin 6	0.130
Pitx1	paired-like homeodomain transcription factor 1	0.111
Tbx3	T-box 3	0.101	Mouse
Tnfrsf9	tumor necrosis factor receptor superfamily, member 9	0.084
Ccr7	chemokine (C-C motif) receptor 7	0.068
Cd40	CD40 antigen	0.064
Tnfsf11	tumor necrosis factor (ligand) superfamily, member 11	0.062
Il27ra	interleukin 27 receptor, alpha	0.060
Rag1	recombination activating gene 1	0.057
Inpp5d	inositol polyphosphate-5-phosphatase D	0.052
Stat3	signal transducer and activator of transcription 3	0.048
Il2rg	interleukin 2 receptor, gamma chain	0.044
Scn5a	sodium channel, voltage-gated, type V, alpha	0.042
Pdcd1	programmed cell death 1	0.041
Cd44	CD44 antigen	0.039
Il4ra	interleukin 4 receptor, alpha	0.039
Cd4	CD4 antigen	0.039
Lat	linker for activation of T cells	0.039
Icos	inducible T-cell co-stimulator	0.038	Mouse
Prf1	perforin 1 (pore forming protein)	0.035
Sall4	sal-like 4 (Drosophila)	0.033
Il12rb1	interleukin 12 receptor, beta 1	0.032
Pik3cd	phosphatidylinositol 3-kinase catalytic delta polypeptide	0.031
Fasl	Fas ligand (TNF superfamily, member 6)	0.029
Btk	Bruton agammaglobulinemia tyrosine kinase	0.028
Cd79a	CD79A antigen (immunoglobulin-associated alpha)	0.027
Sh2d2a	SH2 domain protein 2A	0.027
Cebpb	CCAAT/enhancer binding protein (C/EBP), beta	0.026
Lyn	Yamaguchi sarcoma viral (v-yes-1) oncogene homolog	0.026
Ltb	lymphotoxin B	0.024
Tcrb	T-cell receptor beta chain	0.023
Tbx5	T-box 5	0.023	Mouse
Ccr6	chemokine (C-C motif) receptor 6	0.022
Sh2d1a	SH2 domain protein 1A	0.022
Pitx2	paired-like homeodomain transcription factor 2	0.021
Relb	avian reticuloendotheliosis viral (v-rel) oncogene related B	0.021
Pou5f1	POU domain, class 5, transcription factor 1	0.020
Tnfrsf4	tumor necrosis factor receptor superfamily, member 4	0.020
Zap70	zeta-chain (TCR) associated protein kinase	0.018
Mmp9	matrix metallopeptidase 9	0.018
Foxp2	forkhead box P2	0.018	Mouse
Zeb1	zinc finger E-box binding homeobox 1	0.017
Prrx1	paired related homeobox 1	0.017
Card11	caspase recruitment domain family, member 11	0.016
Batf	basic leucine zipper transcription factor, ATF-like	0.016
Nlrp3	NLR family, pyrin domain containing 3	0.016
Il21r	interleukin 21 receptor	0.016
Il2rb	interleukin 2 receptor, beta chain	0.015
Hcn4	hyperpolarization-activated, cyclic nucleotide-gated K+ 4	0.015
Bcl3	B-cell leukemia/lymphoma 3	0.015
Runx2	runt related transcription factor 2	0.015
Nkx2-5	NK2 transcription factor related, locus 5 (Drosophila)	0.015
Cd40lg	CD40 ligand	0.015
Fgf10	fibroblast growth factor 10	0.015
Itgb2	integrin beta 2	0.014
Chd7	chromodomain helicase DNA binding protein 7	0.014
Hoxa1	homeobox A1	0.014
Cd5	CD5 antigen	0.013
Ccl2	chemokine (C-C motif) ligand 2	0.013
Il18rap	interleukin 18 receptor accessory protein	0.013
Lck	lymphocyte protein tyrosine kinase	0.013
Six1	sine oculis-related homeobox 1 homolog (Drosophila)	0.013
Gpr132	G protein-coupled receptor 132	0.012
Tnfrsf1b	tumor necrosis factor receptor superfamily, member 1b	0.012	Mouse
Hand1	heart and neural crest derivatives expressed transcript 1	0.012
Nos2	nitric oxide synthase 2, inducible	0.012
Gli2	GLI-Kruppel family member GLI2	0.012
Il17a	interleukin 17A	0.011
Ciita	class II transactivator	0.011
Stat6	signal transducer and activator of transcription 6	0.011
Il2	interleukin 2	0.011
Apoe	apolipoprotein E	0.011
Pag1	phosphoprotein associated with glycosphingolipid microdomains 1	0.010
Foxp1	forkhead box P1	0.010	Mouse
Alx1	ALX homeobox 1	0.010
Nfkb1	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1, p105	0.010
Bcl6	B-cell leukemia/lymphoma 6	0.010