IMP
Process View
ciliary neurotrophic factor mediated signaling pathway
A series of molecular signals initiated by the binding of a ciliary neurotrophic factor (CNTF) to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.
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In addition to gene-name show these genes:
Click on a gene's description to view its network relationships with genes known to be involved in "ciliary neurotrophic factor mediated signaling pathway"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| IL6ST | interleukin 6 signal transducer (gp130, oncostatin M receptor) | 1.000 | ||
| JAK1 | Janus kinase 1 | 1.000 | ||
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.999 | ||
| SOCS3 | suppressor of cytokine signaling 3 | 0.994 | ||
| IL6R | interleukin 6 receptor | 0.985 | ||
| IL6 | interleukin 6 (interferon, beta 2) | 0.895 | ||
| JAK2 | Janus kinase 2 | 0.894 | ||
| LIF | leukemia inhibitory factor (cholinergic differentiation factor) | 0.856 | ||
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.850 | ||
| ERBB2 | v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) | 0.570 | ||
| CNTF | ciliary neurotrophic factor | 0.427 | ||
| STAT4 | signal transducer and activator of transcription 4 | 0.336 | ||
| LIFR | leukemia inhibitory factor receptor alpha | 0.214 | ||
| EXT1 | exostosin 1 | 0.139 | ||
| PTPN11 | protein tyrosine phosphatase, non-receptor type 11 | 0.114 | ||
| ICA1 | islet cell autoantigen 1, 69kDa | 0.106 | ||
| STAT2 | signal transducer and activator of transcription 2, 113kDa | 0.082 | ||
| VHL | von Hippel-Lindau tumor suppressor | 0.077 | ||
| EGFR | epidermal growth factor receptor | 0.050 | ||
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | 0.047 | ||
| OSM | oncostatin M | 0.037 | ||
| IL1R1 | interleukin 1 receptor, type I | 0.024 | ||
| GAB1 | GRB2-associated binding protein 1 | 0.024 | ||
| IFNAR2 | interferon (alpha, beta and omega) receptor 2 | 0.021 | ||
| SLA | Src-like-adaptor | 0.019 | ||
| STK16 | serine/threonine kinase 16 | 0.013 | ||
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | 0.013 | ||
| FRS2 | fibroblast growth factor receptor substrate 2 | 0.011 | ||
| IRS1 | insulin receptor substrate 1 | 0.010 |