IMP

Process View

Homo sapiens

2 genes annotated in human

vitamin k biosynthetic process

The chemical reactions and pathways resulting in the formation of any of the forms of vitamin K, quinone-derived vitamins which are involved in the synthesis of blood-clotting factors in mammals.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "vitamin k biosynthetic process"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "vitamin k biosynthetic process" (in gray)

Name	Description	Probability	Func Analog Organism
CYP4F2	cytochrome P450, family 4, subfamily F, polypeptide 2	0.998
CYP4F12	cytochrome P450, family 4, subfamily F, polypeptide 12	0.862	Human
CYP3A43	cytochrome P450, family 3, subfamily A, polypeptide 43	0.837
CYP4F3	cytochrome P450, family 4, subfamily F, polypeptide 3	0.793	Human
CYP2C9	cytochrome P450, family 2, subfamily C, polypeptide 9	0.623
CYP4F11	cytochrome P450, family 4, subfamily F, polypeptide 11	0.534	Human
CYP2B6	cytochrome P450, family 2, subfamily B, polypeptide 6	0.432
SULT1B1	sulfotransferase family, cytosolic, 1B, member 1	0.243
CYP3A4	cytochrome P450, family 3, subfamily A, polypeptide 4	0.208
CYP3A5	cytochrome P450, family 3, subfamily A, polypeptide 5	0.187
CYP2C19	cytochrome P450, family 2, subfamily C, polypeptide 19	0.145
SLC10A1	solute carrier family 10 (sodium/bile acid cotransporter family), member 1	0.136
KNG1	kininogen 1	0.106
CYP3A7	cytochrome P450, family 3, subfamily A, polypeptide 7	0.101
ABCC2	ATP-binding cassette, sub-family C (CFTR/MRP), member 2	0.083
ADH6	alcohol dehydrogenase 6 (class V)	0.082
RDH16	retinol dehydrogenase 16 (all-trans)	0.078
C8A	complement component 8, alpha polypeptide	0.067
DAO	D-amino-acid oxidase	0.067
HMGCS2	3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial)	0.066
FABP1	fatty acid binding protein 1, liver	0.061
AZGP1	alpha-2-glycoprotein 1, zinc-binding	0.060
HAL	histidine ammonia-lyase	0.060
DIO1	deiodinase, iodothyronine, type I	0.057
SULT2A1	sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1	0.054
SCNN1A	sodium channel, nonvoltage-gated 1 alpha	0.053
F9	coagulation factor IX	0.052
MAT1A	methionine adenosyltransferase I, alpha	0.051
CYP4A11	cytochrome P450, family 4, subfamily A, polypeptide 11	0.050	Human
FETUB	fetuin B	0.049
CYP2C18	cytochrome P450, family 2, subfamily C, polypeptide 18	0.046
G6PC	glucose-6-phosphatase, catalytic subunit	0.044
PLG	plasminogen	0.043
DPH2	DPH2 homolog (S. cerevisiae)	0.040
AGXT	alanine-glyoxylate aminotransferase	0.039
C4BPA	complement component 4 binding protein, alpha	0.038
SERPINA6	serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 6	0.037
CEACAM6	carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)	0.036
NOP14	NOP14 nucleolar protein homolog (yeast)	0.036
OTC	ornithine carbamoyltransferase	0.036
AKR1C4	aldo-keto reductase family 1, member C4 (chlordecone reductase; 3-alpha hydroxysteroid dehydrogenase, type I; dihydrodiol dehydrogenase 4)	0.034
HAO1	hydroxyacid oxidase (glycolate oxidase) 1	0.034
AADAC	arylacetamide deacetylase (esterase)	0.032
SULT1E1	sulfotransferase family 1E, estrogen-preferring, member 1	0.032
PAH	phenylalanine hydroxylase	0.030
ARG1	arginase, liver	0.030
MASP2	mannan-binding lectin serine peptidase 2	0.030
HNF4A	hepatocyte nuclear factor 4, alpha	0.029
PKLR	pyruvate kinase, liver and RBC	0.028
DHX37	DEAH (Asp-Glu-Ala-His) box polypeptide 37	0.028
HGD	homogentisate 1,2-dioxygenase	0.026
PCK1	phosphoenolpyruvate carboxykinase 1 (soluble)	0.026
SLC22A1	solute carrier family 22 (organic cation transporter), member 1	0.025
EPHX2	epoxide hydrolase 2, cytoplasmic	0.025
GSTA3	glutathione S-transferase alpha 3	0.025
CYP2E1	cytochrome P450, family 2, subfamily E, polypeptide 1	0.025
CYP4F8	cytochrome P450, family 4, subfamily F, polypeptide 8	0.024	Human
GLYAT	glycine-N-acyltransferase	0.024
APOC3	apolipoprotein C-III	0.024
CYP2C8	cytochrome P450, family 2, subfamily C, polypeptide 8	0.024
PIP	prolactin-induced protein	0.024
CYP1A1	cytochrome P450, family 1, subfamily A, polypeptide 1	0.024
CYP2J2	cytochrome P450, family 2, subfamily J, polypeptide 2	0.023
HPD	4-hydroxyphenylpyruvate dioxygenase	0.023
GBA3	glucosidase, beta, acid 3 (cytosolic)	0.023
SULT2B1	sulfotransferase family, cytosolic, 2B, member 1	0.023
AQP7	aquaporin 7	0.022
SERPINC1	serpin peptidase inhibitor, clade C (antithrombin), member 1	0.022
ADH1C	alcohol dehydrogenase 1C (class I), gamma polypeptide	0.022
TMPRSS4	transmembrane protease, serine 4	0.021
C8B	complement component 8, beta polypeptide	0.021
APOF	apolipoprotein F	0.021
CYP4B1	cytochrome P450, family 4, subfamily B, polypeptide 1	0.021	Human
SEC14L2	SEC14-like 2 (S. cerevisiae)	0.021
C6	complement component 6	0.020
FUT6	fucosyltransferase 6 (alpha (1,3) fucosyltransferase)	0.020
CPB2	carboxypeptidase B2 (plasma)	0.020
KRT13	keratin 13	0.019
SCGB2A1	secretoglobin, family 2A, member 1	0.019
F13B	coagulation factor XIII, B polypeptide	0.019
SLC2A2	solute carrier family 2 (facilitated glucose transporter), member 2	0.019
ABCB11	ATP-binding cassette, sub-family B (MDR/TAP), member 11	0.019
UGT1A3	UDP glucuronosyltransferase 1 family, polypeptide A3	0.018
NLE1	notchless homolog 1 (Drosophila)	0.018
BAAT	bile acid CoA: amino acid N-acyltransferase (glycine N-choloyltransferase)	0.018
GPT	glutamic-pyruvate transaminase (alanine aminotransferase)	0.018
GRWD1	glutamate-rich WD repeat containing 1	0.017
LIPC	lipase, hepatic	0.017
NAT2	N-acetyltransferase 2 (arylamine N-acetyltransferase)	0.017
C9	complement component 9	0.017
DEFB1	defensin, beta 1	0.017
ORM1	orosomucoid 1	0.017
SPP2	secreted phosphoprotein 2, 24kDa	0.016
GSTT1	glutathione S-transferase theta 1	0.016
NAT8	N-acetyltransferase 8 (GCN5-related, putative)	0.016
HSD17B2	hydroxysteroid (17-beta) dehydrogenase 2	0.016
LPA	lipoprotein, Lp(a)	0.015
BBOX1	butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1	0.015
PMM2	phosphomannomutase 2	0.015
HPX	hemopexin	0.015
ORM2	orosomucoid 2	0.014
METTL1	methyltransferase like 1	0.014
CEACAM8	carcinoembryonic antigen-related cell adhesion molecule 8	0.014
F5	coagulation factor V (proaccelerin, labile factor)	0.014
GPX2	glutathione peroxidase 2 (gastrointestinal)	0.013
C8G	complement component 8, gamma polypeptide	0.013
TRMT61A	tRNA methyltransferase 61 homolog A (S. cerevisiae)	0.013
CLDN8	claudin 8	0.013
PPRC1	peroxisome proliferator-activated receptor gamma, coactivator-related 1	0.013
NOP2	NOP2 nucleolar protein homolog (yeast)	0.013
CCDC86	coiled-coil domain containing 86	0.013
KHK	ketohexokinase (fructokinase)	0.013
VTCN1	V-set domain containing T cell activation inhibitor 1	0.013
ALDH1L1	aldehyde dehydrogenase 1 family, member L1	0.013
CNGA1	cyclic nucleotide gated channel alpha 1	0.013
ADH1A	alcohol dehydrogenase 1A (class I), alpha polypeptide	0.013
CRISP3	cysteine-rich secretory protein 3	0.013
CFHR4	complement factor H-related 4	0.013
AKR1D1	aldo-keto reductase family 1, member D1 (delta 4-3-ketosteroid-5-beta-reductase)	0.013
APOH	apolipoprotein H (beta-2-glycoprotein I)	0.013
LETM1	leucine zipper-EF-hand containing transmembrane protein 1	0.013
CRP	C-reactive protein, pentraxin-related	0.012
SLC22A7	solute carrier family 22 (organic anion transporter), member 7	0.012
SLC38A3	solute carrier family 38, member 3	0.012
S100A14	S100 calcium binding protein A14	0.012
HSD11B2	hydroxysteroid (11-beta) dehydrogenase 2	0.012
IL22RA1	interleukin 22 receptor, alpha 1	0.012
SLC13A2	solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2	0.012
RBP2	retinol binding protein 2, cellular	0.012
CDA	cytidine deaminase	0.012
NR1I3	nuclear receptor subfamily 1, group I, member 3	0.011
FABP2	fatty acid binding protein 2, intestinal	0.011
PIPOX	pipecolic acid oxidase	0.011
PRODH	proline dehydrogenase (oxidase) 1	0.011
AKR1B10	aldo-keto reductase family 1, member B10 (aldose reductase)	0.011
ABP1	amiloride binding protein 1 (amine oxidase (copper-containing))	0.011
SLC5A6	solute carrier family 5 (sodium-dependent vitamin transporter), member 6	0.011
SCNN1B	sodium channel, nonvoltage-gated 1, beta	0.011
F12	coagulation factor XII (Hageman factor)	0.011
TMC5	transmembrane channel-like 5	0.011
CYP8B1	cytochrome P450, family 8, subfamily B, polypeptide 1	0.011
ALDH3A1	aldehyde dehydrogenase 3 family, member A1	0.011
NR1I2	nuclear receptor subfamily 1, group I, member 2	0.011
SERPINA10	serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10	0.011
ANXA13	annexin A13	0.011
KRT4	keratin 4	0.010
MOSC1	MOCO sulphurase C-terminal domain containing 1	0.010
ACSM5	acyl-CoA synthetase medium-chain family member 5	0.010
KLKB1	kallikrein B, plasma (Fletcher factor) 1	0.010
CDHR5	cadherin-related family member 5	0.010
UGT2B4	UDP glucuronosyltransferase 2 family, polypeptide B4	0.010