IMP
Process View
cortisol biosynthetic process
The chemical reactions and pathways resulting in the formation of cortisol, the steroid hormone 11-beta-17,21-trihydroxypregn-4-ene-3,20-dione. Cortisol is synthesized from cholesterol in the adrenal gland and controls carbohydrate, fat and protein metabolism and has anti-inflammatory properties.
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In addition to gene-name show these genes:
Click on a gene's description to view its network relationships with genes known to be involved in "cortisol biosynthetic process"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| BMPR1A | bone morphogenetic protein receptor, type IA | 0.999 | ||
| WFIKKN2 | WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2 | 0.976 | ||
| NOG | noggin | 0.574 | ||
| FSTL1 | follistatin-like 1 | 0.534 | ||
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | 0.493 | ||
| WFIKKN1 | WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 1 | 0.425 | ||
| ZFYVE9 | zinc finger, FYVE domain containing 9 | 0.238 | ||
| FGF18 | fibroblast growth factor 18 | 0.146 | ||
| MAPK15 | mitogen-activated protein kinase 15 | 0.115 | ||
| FGF4 | fibroblast growth factor 4 | 0.084 | ||
| WNT4 | wingless-type MMTV integration site family, member 4 | 0.075 | ||
| COL2A1 | collagen, type II, alpha 1 | 0.057 | ||
| WNT6 | wingless-type MMTV integration site family, member 6 | 0.056 | Human | |
| SFRP1 | secreted frizzled-related protein 1 | 0.033 | ||
| ST8SIA2 | ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2 | 0.029 | ||
| WNT11 | wingless-type MMTV integration site family, member 11 | 0.029 | Human | |
| SOX21 | SRY (sex determining region Y)-box 21 | 0.028 | ||
| MMP11 | matrix metallopeptidase 11 (stromelysin 3) | 0.027 | ||
| RAX | retina and anterior neural fold homeobox | 0.026 | ||
| HRH3 | histamine receptor H3 | 0.026 | ||
| BMP4 | bone morphogenetic protein 4 | 0.026 | Human | |
| BMPR1B | bone morphogenetic protein receptor, type IB | 0.025 | ||
| WIF1 | WNT inhibitory factor 1 | 0.025 | ||
| IHH | Indian hedgehog | 0.023 | ||
| PTGIS | prostaglandin I2 (prostacyclin) synthase | 0.021 | ||
| DLX4 | distal-less homeobox 4 | 0.018 | ||
| TG | thyroglobulin | 0.018 | ||
| SOX1 | SRY (sex determining region Y)-box 1 | 0.018 | ||
| FOXF2 | forkhead box F2 | 0.018 | ||
| WNT3 | wingless-type MMTV integration site family, member 3 | 0.017 | Human | |
| HMX1 | H6 family homeobox 1 | 0.017 | ||
| BMP8A | bone morphogenetic protein 8a | 0.016 | Human | |
| NXPH3 | neurexophilin 3 | 0.016 | ||
| FZD10 | frizzled homolog 10 (Drosophila) | 0.016 | ||
| PITX3 | paired-like homeodomain 3 | 0.016 | ||
| FOXC2 | forkhead box C2 (MFH-1, mesenchyme forkhead 1) | 0.016 | ||
| KREMEN2 | kringle containing transmembrane protein 2 | 0.015 | ||
| ALX4 | ALX homeobox 4 | 0.015 | ||
| HS3ST6 | heparan sulfate (glucosamine) 3-O-sulfotransferase 6 | 0.015 | ||
| EFNB3 | ephrin-B3 | 0.014 | ||
| AQP5 | aquaporin 5 | 0.014 | ||
| ACAN | aggrecan | 0.013 | ||
| PTH1R | parathyroid hormone 1 receptor | 0.012 | ||
| CHRNA4 | cholinergic receptor, nicotinic, alpha 4 | 0.012 | ||
| TGFB1 | transforming growth factor, beta 1 | 0.012 | ||
| AVPR1B | arginine vasopressin receptor 1B | 0.012 | ||
| KCNK9 | potassium channel, subfamily K, member 9 | 0.011 | ||
| BMP3 | bone morphogenetic protein 3 | 0.011 | Human | |
| EPHB3 | EPH receptor B3 | 0.011 | ||
| ALB | albumin | 0.011 | ||
| WNT1 | wingless-type MMTV integration site family, member 1 | 0.011 | Human | |
| SOD3 | superoxide dismutase 3, extracellular | 0.011 | ||
| LBX1 | ladybird homeobox 1 | 0.010 | ||
| SCRT1 | scratch homolog 1, zinc finger protein (Drosophila) | 0.010 | ||
| BMP7 | bone morphogenetic protein 7 | 0.010 | Human | |
| PKP1 | plakophilin 1 (ectodermal dysplasia/skin fragility syndrome) | 0.010 | ||
| FOXD3 | forkhead box D3 | 0.010 | ||
| ROR2 | receptor tyrosine kinase-like orphan receptor 2 | 0.010 | ||
| JPH3 | junctophilin 3 | 0.010 |