IMP
Process View
negative regulation of nuclease activity
Any process that stops or reduces the rate of nuclease activity, the hydrolysis of ester linkages within nucleic acids.
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Click on a gene's description to view its network relationships with genes known to be involved in "negative regulation of nuclease activity"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| GNLY | granulysin | 0.998 | ||
| PRF1 | perforin 1 (pore forming protein) | 0.990 | ||
| NKG7 | natural killer cell group 7 sequence | 0.773 | ||
| GZMK | granzyme K (granzyme 3; tryptase II) | 0.718 | Human | |
| GZMB | granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) | 0.490 | Human | |
| CD8A | CD8a molecule | 0.478 | ||
| GZMA | granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3) | 0.367 | ||
| CTSW | cathepsin W | 0.363 | ||
| KLRD1 | killer cell lectin-like receptor subfamily D, member 1 | 0.358 | ||
| CST7 | cystatin F (leukocystatin) | 0.329 | ||
| GZMH | granzyme H (cathepsin G-like 2, protein h-CCPX) | 0.199 | Human | |
| KLRK1 | killer cell lectin-like receptor subfamily K, member 1 | 0.195 | ||
| IL18RAP | interleukin 18 receptor accessory protein | 0.139 | ||
| CXCR6 | chemokine (C-X-C motif) receptor 6 | 0.111 | ||
| KLRB1 | killer cell lectin-like receptor subfamily B, member 1 | 0.105 | ||
| CD3D | CD3d molecule, delta (CD3-TCR complex) | 0.102 | ||
| IL2RB | interleukin 2 receptor, beta | 0.090 | ||
| CCL5 | chemokine (C-C motif) ligand 5 | 0.085 | ||
| CCL4 | chemokine (C-C motif) ligand 4 | 0.068 | ||
| GPR171 | G protein-coupled receptor 171 | 0.063 | ||
| ITK | IL2-inducible T-cell kinase | 0.036 | ||
| GZMM | granzyme M (lymphocyte met-ase 1) | 0.035 | ||
| IFNG | interferon, gamma | 0.035 | ||
| SRGN | serglycin | 0.034 | ||
| CD160 | CD160 molecule | 0.034 | ||
| TRAT1 | T cell receptor associated transmembrane adaptor 1 | 0.031 | ||
| PVRIG | poliovirus receptor related immunoglobulin domain containing | 0.030 | ||
| CD2 | CD2 molecule | 0.028 | ||
| C1QA | complement component 1, q subcomponent, A chain | 0.026 | ||
| KLRF1 | killer cell lectin-like receptor subfamily F, member 1 | 0.025 | ||
| F13A1 | coagulation factor XIII, A1 polypeptide | 0.024 | ||
| ELANE | elastase, neutrophil expressed | 0.023 | ||
| XCL2 | chemokine (C motif) ligand 2 | 0.021 | ||
| IGJ | immunoglobulin J polypeptide, linker protein for immunoglobulin alpha and mu polypeptides | 0.020 | ||
| SLAMF7 | SLAM family member 7 | 0.020 | ||
| IGL@ | immunoglobulin lambda locus | 0.020 | ||
| CLEC10A | C-type lectin domain family 10, member A | 0.020 | ||
| FASLG | Fas ligand (TNF superfamily, member 6) | 0.019 | ||
| TBX21 | T-box 21 | 0.017 | ||
| FCN1 | ficolin (collagen/fibrinogen domain containing) 1 | 0.016 | ||
| IL18R1 | interleukin 18 receptor 1 | 0.014 | ||
| CD96 | CD96 molecule | 0.013 | ||
| KLRG1 | killer cell lectin-like receptor subfamily G, member 1 | 0.013 | ||
| GFI1 | growth factor independent 1 transcription repressor | 0.013 | ||
| CD3G | CD3g molecule, gamma (CD3-TCR complex) | 0.013 | ||
| AOAH | acyloxyacyl hydrolase (neutrophil) | 0.013 | ||
| CXCR3 | chemokine (C-X-C motif) receptor 3 | 0.012 | ||
| ITGB7 | integrin, beta 7 | 0.012 | ||
| CTSG | cathepsin G | 0.011 | Human | |
| CPA3 | carboxypeptidase A3 (mast cell) | 0.011 | ||
| LAIR2 | leukocyte-associated immunoglobulin-like receptor 2 | 0.011 | ||
| IL10RA | interleukin 10 receptor, alpha | 0.011 |