IMP

Process View

Homo sapiens

1 genes annotated in human

pulmonary valve formation

The developmental process pertaining to the initial formation of the pulmonary valve from unspecified parts. This process begins with the specific processes that contribute to the appearance of the discrete structure and ends when the structural rudiment is recognizable.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "pulmonary valve formation"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "pulmonary valve formation" (in gray)

Name	Description	Probability	Func Analog Organism
TRIM29	tripartite motif containing 29	0.772
LAD1	ladinin 1	0.472
FGFBP1	fibroblast growth factor binding protein 1	0.401
GJB5	gap junction protein, beta 5, 31.1kDa	0.358	Human
KLK10	kallikrein-related peptidase 10	0.222
COL17A1	collagen, type XVII, alpha 1	0.199
PKP3	plakophilin 3	0.181
SFN	stratifin	0.168
FXYD3	FXYD domain containing ion transport regulator 3	0.120
SERPINB5	serpin peptidase inhibitor, clade B (ovalbumin), member 5	0.116
VWF	von Willebrand factor	0.115
KRT6B	keratin 6B	0.109
KRT16	keratin 16	0.077
GJB3	gap junction protein, beta 3, 31kDa	0.077	Human
LAMC2	laminin, gamma 2	0.076
TNS4	tensin 4	0.076
KRT17	keratin 17	0.070
CRHR2	corticotropin releasing hormone receptor 2	0.069
RIMS3	regulating synaptic membrane exocytosis 3	0.063
PKP1	plakophilin 1 (ectodermal dysplasia/skin fragility syndrome)	0.062
C20orf4	chromosome 20 open reading frame 4	0.061
S100A14	S100 calcium binding protein A14	0.055
KRT6A	keratin 6A	0.055
KRT14	keratin 14	0.054
SPRR1B	small proline-rich protein 1B	0.054
KRT75	keratin 75	0.053
VGLL1	vestigial like 1 (Drosophila)	0.053
AQP5	aquaporin 5	0.050
SCEL	sciellin	0.047
IVL	involucrin	0.047
MST1R	macrophage stimulating 1 receptor (c-met-related tyrosine kinase)	0.046
DSG3	desmoglein 3	0.045
FOXN1	forkhead box N1	0.040
MYL2	myosin, light chain 2, regulatory, cardiac, slow	0.039
LY6D	lymphocyte antigen 6 complex, locus D	0.038
KRT5	keratin 5	0.038
KLK5	kallikrein-related peptidase 5	0.037
SPRR1A	small proline-rich protein 1A	0.037
PLEKHG3	pleckstrin homology domain containing, family G (with RhoGef domain) member 3	0.035
ALS2CL	ALS2 C-terminal like	0.033
NPR1	natriuretic peptide receptor A/guanylate cyclase A (atrionatriuretic peptide receptor A)	0.031
CDH3	cadherin 3, type 1, P-cadherin (placental)	0.031
NKX6-1	NK6 homeobox 1	0.028
SOX15	SRY (sex determining region Y)-box 15	0.028
IFNA17	interferon, alpha 17	0.027
TNK1	tyrosine kinase, non-receptor, 1	0.027
CACNA1F	calcium channel, voltage-dependent, L type, alpha 1F subunit	0.026
ARTN	artemin	0.026
SLC6A7	solute carrier family 6 (neurotransmitter transporter, L-proline), member 7	0.026
KRT6C	keratin 6C	0.025
POU4F3	POU class 4 homeobox 3	0.025
TMEM40	transmembrane protein 40	0.024
ALPP	alkaline phosphatase, placental	0.024
GPX2	glutathione peroxidase 2 (gastrointestinal)	0.024
ERN2	endoplasmic reticulum to nucleus signaling 2	0.023
PLEK2	pleckstrin 2	0.023
KCNK7	potassium channel, subfamily K, member 7	0.023
KLK6	kallikrein-related peptidase 6	0.022
LBX1	ladybird homeobox 1	0.022
KRT9	keratin 9	0.022
CD14	CD14 molecule	0.022
ALB	albumin	0.022
LHX3	LIM homeobox 3	0.022
PADI3	peptidyl arginine deiminase, type III	0.021
FERMT1	fermitin family member 1	0.021
IRF6	interferon regulatory factor 6	0.021
MYBPC2	myosin binding protein C, fast type	0.020
EVPL	envoplakin	0.020
TINAGL1	tubulointerstitial nephritis antigen-like 1	0.020
PADI1	peptidyl arginine deiminase, type I	0.020
PRSS50	protease, serine, 50	0.020
CRCT1	cysteine-rich C-terminal 1	0.020
TP63	tumor protein p63	0.019
MALL	mal, T-cell differentiation protein-like	0.019
FUT1	fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group)	0.019
PSG9	pregnancy specific beta-1-glycoprotein 9	0.019
FGF22	fibroblast growth factor 22	0.018
HR	hairless homolog (mouse)	0.018
C1orf116	chromosome 1 open reading frame 116	0.018
HIGD1B	HIG1 hypoxia inducible domain family, member 1B	0.018
EPHX3	epoxide hydrolase 3	0.018
KLC3	kinesin light chain 3	0.018
ACTN3	actinin, alpha 3	0.018
GABRP	gamma-aminobutyric acid (GABA) A receptor, pi	0.017
TIE1	tyrosine kinase with immunoglobulin-like and EGF-like domains 1	0.017
PHOX2A	paired-like homeobox 2a	0.017
IL1RL2	interleukin 1 receptor-like 2	0.017
PVRL1	poliovirus receptor-related 1 (herpesvirus entry mediator C)	0.017
HNF4A	hepatocyte nuclear factor 4, alpha	0.017
HSF2BP	heat shock transcription factor 2 binding protein	0.016
B3GNT3	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3	0.016
S100A2	S100 calcium binding protein A2	0.016
GPR87	G protein-coupled receptor 87	0.016
PI3	peptidase inhibitor 3, skin-derived	0.016
TCL1B	T-cell leukemia/lymphoma 1B	0.016
MARK1	MAP/microtubule affinity-regulating kinase 1	0.016
ENTPD2	ectonucleoside triphosphate diphosphohydrolase 2	0.016
RHOD	ras homolog gene family, member D	0.016
TGFA	transforming growth factor, alpha	0.015
IHH	Indian hedgehog	0.015
IL22RA1	interleukin 22 receptor, alpha 1	0.015
FAT2	FAT tumor suppressor homolog 2 (Drosophila)	0.015
CRYBB3	crystallin, beta B3	0.015
KLK11	kallikrein-related peptidase 11	0.015
PVRL4	poliovirus receptor-related 4	0.015
CARD10	caspase recruitment domain family, member 10	0.015
DSC3	desmocollin 3	0.015
TGM5	transglutaminase 5	0.015
C19orf57	chromosome 19 open reading frame 57	0.015
SOX17	SRY (sex determining region Y)-box 17	0.014
KRT23	keratin 23 (histone deacetylase inducible)	0.014
ECE2	endothelin converting enzyme 2	0.014
CD34	CD34 molecule	0.014
NNAT	neuronatin	0.014
S1PR5	sphingosine-1-phosphate receptor 5	0.014
ALLC	allantoicase	0.014
MMP7	matrix metallopeptidase 7 (matrilysin, uterine)	0.014
DKK4	dickkopf homolog 4 (Xenopus laevis)	0.014
ALDH3A1	aldehyde dehydrogenase 3 family, member A1	0.014
MAT1A	methionine adenosyltransferase I, alpha	0.014
WNT10B	wingless-type MMTV integration site family, member 10B	0.014
PLVAP	plasmalemma vesicle associated protein	0.014
TLX1	T-cell leukemia homeobox 1	0.013
MYLPF	myosin light chain, phosphorylatable, fast skeletal muscle	0.013
PPY	pancreatic polypeptide	0.013
ZBED2	zinc finger, BED-type containing 2	0.013
CHRNG	cholinergic receptor, nicotinic, gamma	0.013
FHL3	four and a half LIM domains 3	0.013
KRT19	keratin 19	0.013
CHIA	chitinase, acidic	0.013
SRPK3	SRSF protein kinase 3	0.013
GCM1	glial cells missing homolog 1 (Drosophila)	0.013
SPRR2B	small proline-rich protein 2B	0.013
CPN1	carboxypeptidase N, polypeptide 1	0.013
PCDH12	protocadherin 12	0.013
DUSP13	dual specificity phosphatase 13	0.013
PAX4	paired box 4	0.013
RAB3IL1	RAB3A interacting protein (rabin3)-like 1	0.013
HOXD12	homeobox D12	0.013
EPHA2	EPH receptor A2	0.013
CST2	cystatin SA	0.013
CLDN4	claudin 4	0.013
C15orf2	chromosome 15 open reading frame 2	0.013
LPAR3	lysophosphatidic acid receptor 3	0.012
KRT81	keratin 81	0.012
SERPINB7	serpin peptidase inhibitor, clade B (ovalbumin), member 7	0.012
TTC22	tetratricopeptide repeat domain 22	0.012
OVOL1	ovo-like 1(Drosophila)	0.012
KRT4	keratin 4	0.012
EVX1	even-skipped homeobox 1	0.012
CD207	CD207 molecule, langerin	0.012
SEMA3G	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3G	0.012
C1orf106	chromosome 1 open reading frame 106	0.012
TG	thyroglobulin	0.012
FRMD1	FERM domain containing 1	0.012
ABCA12	ATP-binding cassette, sub-family A (ABC1), member 12	0.012
ACVRL1	activin A receptor type II-like 1	0.012
HYAL1	hyaluronoglucosaminidase 1	0.012
SPRR3	small proline-rich protein 3	0.012
KLK8	kallikrein-related peptidase 8	0.012
TMSB4Y	thymosin beta 4, Y-linked	0.012
ENDOU	endonuclease, polyU-specific	0.012
DSG1	desmoglein 1	0.012
CCIN	calicin	0.012
SLC17A9	solute carrier family 17, member 9	0.012
SSTR3	somatostatin receptor 3	0.011
IL1F10	interleukin 1 family, member 10 (theta)	0.011
TCF15	transcription factor 15 (basic helix-loop-helix)	0.011
ACTL8	actin-like 8	0.011
KRT33A	keratin 33A	0.011
CLCA2	chloride channel accessory 2	0.011
KRT2	keratin 2	0.011
RAMP2	receptor (G protein-coupled) activity modifying protein 2	0.011
HOXB9	homeobox B9	0.011
HIST1H3C	histone cluster 1, H3c	0.011
CLDN16	claudin 16	0.011
SLC5A1	solute carrier family 5 (sodium/glucose cotransporter), member 1	0.011
SLURP1	secreted LY6/PLAUR domain containing 1	0.011
IGFL1	IGF-like family member 1	0.011
PRODH	proline dehydrogenase (oxidase) 1	0.011
VSNL1	visinin-like 1	0.011
CXorf36	chromosome X open reading frame 36	0.011
S1PR2	sphingosine-1-phosphate receptor 2	0.011
MUC16	mucin 16, cell surface associated	0.011
JUB	jub, ajuba homolog (Xenopus laevis)	0.011
KRT12	keratin 12	0.011
FOXE1	forkhead box E1 (thyroid transcription factor 2)	0.011
TNNT3	troponin T type 3 (skeletal, fast)	0.011
TBX10	T-box 10	0.011
CIDEA	cell death-inducing DFFA-like effector a	0.011
BMP10	bone morphogenetic protein 10	0.011
HSD17B2	hydroxysteroid (17-beta) dehydrogenase 2	0.011
HIST1H3J	histone cluster 1, H3j	0.011
AZGP1	alpha-2-glycoprotein 1, zinc-binding	0.011
MSLN	mesothelin	0.011
SPERT	spermatid associated	0.011
FCN3	ficolin (collagen/fibrinogen domain containing) 3 (Hakata antigen)	0.011
P2RY2	purinergic receptor P2Y, G-protein coupled, 2	0.010
C12orf39	chromosome 12 open reading frame 39	0.010
CD1A	CD1a molecule	0.010
ITIH2	inter-alpha (globulin) inhibitor H2	0.010
CA9	carbonic anhydrase IX	0.010
GCC1	GRIP and coiled-coil domain containing 1	0.010
LOC100288413	similar to Uncharacterized protein LP9056	0.010
ITGB6	integrin, beta 6	0.010
S100A3	S100 calcium binding protein A3	0.010
CRB3	crumbs homolog 3 (Drosophila)	0.010
TMPRSS11E	transmembrane protease, serine 11E	0.010
SLC6A9	solute carrier family 6 (neurotransmitter transporter, glycine), member 9	0.010
KRT31	keratin 31	0.010
CST6	cystatin E/M	0.010
WNT3	wingless-type MMTV integration site family, member 3	0.010
WFDC5	WAP four-disulfide core domain 5	0.010
UGT1A3	UDP glucuronosyltransferase 1 family, polypeptide A3	0.010
SYNGR4	synaptogyrin 4	0.010
FOXC2	forkhead box C2 (MFH-1, mesenchyme forkhead 1)	0.010
OR2C1	olfactory receptor, family 2, subfamily C, member 1	0.010
ETV3	ets variant 3	0.010
EDN2	endothelin 2	0.010
CALML3	calmodulin-like 3	0.010