IMP
Process View
cholesterol catabolic process
The chemical reactions and pathways resulting in the breakdown of cholesterol, cholest-5-en-3 beta-ol, the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones.
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In addition to gene-name show these genes:
Click on a gene's description to view its network relationships with genes known to be involved in "cholesterol catabolic process"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| Apoa1 | apolipoprotein A-I | 0.428 | Mouse | |
| Prnp | prion protein | 0.331 | ||
| Abca1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.145 | ||
| Mt1 | metallothionein 1 | 0.130 | ||
| F12 | coagulation factor XII (Hageman factor) | 0.109 | ||
| Lrp1 | low density lipoprotein receptor-related protein 1 | 0.091 | ||
| Mosc1 | MOCO sulphurase C-terminal domain containing 1 | 0.088 | ||
| Ghr | growth hormone receptor | 0.070 | ||
| Hsd3b7 | hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7 | 0.063 | ||
| Ifngr1 | interferon gamma receptor 1 | 0.058 | ||
| Agt | angiotensinogen (serpin peptidase inhibitor, clade A, member 8) | 0.051 | ||
| Cav1 | caveolin 1, caveolae protein | 0.047 | ||
| Aldob | aldolase B, fructose-bisphosphate | 0.040 | ||
| Pparg | peroxisome proliferator activated receptor gamma | 0.038 | ||
| Hpd | 4-hydroxyphenylpyruvic acid dioxygenase | 0.038 | ||
| Apoc4 | apolipoprotein C-IV | 0.035 | ||
| Gcgr | glucagon receptor | 0.033 | ||
| Apob | apolipoprotein B | 0.032 | ||
| Cebpa | CCAAT/enhancer binding protein (C/EBP), alpha | 0.031 | ||
| Cfh | complement component factor h | 0.030 | ||
| Cyp8b1 | cytochrome P450, family 8, subfamily b, polypeptide 1 | 0.029 | Mouse | |
| Cyp2d10 | cytochrome P450, family 2, subfamily d, polypeptide 10 | 0.029 | ||
| Cyp4a14 | cytochrome P450, family 4, subfamily a, polypeptide 14 | 0.028 | ||
| G6pc | glucose-6-phosphatase, catalytic | 0.028 | ||
| Lpl | lipoprotein lipase | 0.027 | ||
| Abcc6 | ATP-binding cassette, sub-family C (CFTR/MRP), member 6 | 0.026 | ||
| Apoe | apolipoprotein E | 0.025 | ||
| Nr1i3 | nuclear receptor subfamily 1, group I, member 3 | 0.024 | ||
| Apoc3 | apolipoprotein C-III | 0.022 | ||
| Gc | group specific component | 0.021 | ||
| Slc10a1 | solute carrier family 10 (sodium/bile acid cotransporter family), member 1 | 0.021 | ||
| Nr1i2 | nuclear receptor subfamily 1, group I, member 2 | 0.019 | ||
| 1300017J02Rik | RIKEN cDNA 1300017J02 gene | 0.019 | ||
| Npc1 | Niemann Pick type C1 | 0.019 | ||
| Scd1 | stearoyl-Coenzyme A desaturase 1 | 0.019 | ||
| Gjb2 | gap junction protein, beta 2 | 0.019 | ||
| Cyp2a12 | cytochrome P450, family 2, subfamily a, polypeptide 12 | 0.018 | ||
| Baat | bile acid-Coenzyme A: amino acid N-acyltransferase | 0.018 | ||
| Gck | glucokinase | 0.018 | ||
| Pltp | phospholipid transfer protein | 0.017 | ||
| Pklr | pyruvate kinase liver and red blood cell | 0.017 | ||
| Cyp2c38 | cytochrome P450, family 2, subfamily c, polypeptide 38 | 0.016 | ||
| F13b | coagulation factor XIII, beta subunit | 0.016 | ||
| Ahsg | alpha-2-HS-glycoprotein | 0.015 | ||
| Slc2a4 | solute carrier family 2 (facilitated glucose transporter), member 4 | 0.015 | ||
| Gulo | gulonolactone (L-) oxidase | 0.015 | ||
| Otc | ornithine transcarbamylase | 0.014 | ||
| Slc27a5 | solute carrier family 27 (fatty acid transporter), member 5 | 0.014 | ||
| Ldlr | low density lipoprotein receptor | 0.014 | ||
| Gjb1 | gap junction protein, beta 1 | 0.014 | ||
| Tat | tyrosine aminotransferase | 0.014 | ||
| Nr0b2 | nuclear receptor subfamily 0, group B, member 2 | 0.014 | ||
| Mbl2 | mannose-binding lectin (protein C) 2 | 0.014 | ||
| Angptl4 | angiopoietin-like 4 | 0.014 | ||
| Keg1 | kidney expressed gene 1 | 0.014 | ||
| F9 | coagulation factor IX | 0.013 | ||
| C3 | complement component 3 | 0.013 | ||
| Fga | fibrinogen alpha chain | 0.013 | ||
| Cyp3a25 | cytochrome P450, family 3, subfamily a, polypeptide 25 | 0.013 | ||
| Hsd11b1 | hydroxysteroid 11-beta dehydrogenase 1 | 0.013 | ||
| Cdhr5 | cadherin-related family member 5 | 0.012 | ||
| Prodh2 | proline dehydrogenase (oxidase) 2 | 0.012 | ||
| Cps1 | carbamoyl-phosphate synthetase 1 | 0.012 | ||
| Tspan4 | tetraspanin 4 | 0.012 | ||
| Abcb11 | ATP-binding cassette, sub-family B (MDR/TAP), member 11 | 0.012 | ||
| Klf15 | Kruppel-like factor 15 | 0.012 | ||
| Rdh16 | retinol dehydrogenase 16 | 0.011 | ||
| Serpina6 | serine (or cysteine) peptidase inhibitor, clade A, member 6 | 0.011 | ||
| Cd36 | CD36 antigen | 0.011 | Mouse | |
| Agmat | agmatine ureohydrolase (agmatinase) | 0.011 | ||
| Abhd5 | abhydrolase domain containing 5 | 0.011 | ||
| Habp2 | hyaluronic acid binding protein 2 | 0.011 | ||
| Slc38a3 | solute carrier family 38, member 3 | 0.011 | ||
| Lpin1 | lipin 1 | 0.011 | ||
| Agtr1a | angiotensin II receptor, type 1a | 0.011 | ||
| Dmgdh | dimethylglycine dehydrogenase precursor | 0.011 | ||
| Pnpla2 | patatin-like phospholipase domain containing 2 | 0.011 | ||
| Slc12a6 | solute carrier family 12, member 6 | 0.010 | ||
| Lcat | lecithin cholesterol acyltransferase | 0.010 |