IMP

Process View

3 genes annotated in mouse

b cell selection

The process dependent upon B cell antigen receptor signaling in response to self or foreign antigen through which B cells are selected for survival.

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Known genes in the process in mouse Include functional analogs

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Name	Description	Probability	Func Analog Organism
Bcl2l11	BCL2-like 11 (apoptosis facilitator)	0.992
H2-Aa	histocompatibility 2, class II antigen A, alpha	0.988
Bax	BCL2-associated X protein	0.893
Cd74	CD74 antigen (invariant polypeptide of major histocompatibility complex, class II antigen-associated)	0.824
Bcl2	B-cell leukemia/lymphoma 2	0.592	Mouse
Trp53	transformation related protein 53	0.488
H2-DMa	histocompatibility 2, class II, locus DMa	0.435
Bak1	BCL2-antagonist/killer 1	0.167
Igh	immunoglobulin heavy chain complex	0.052
Kit	kit oncogene	0.047
Pmaip1	phorbol-12-myristate-13-acetate-induced protein 1	0.046
H2-Eb1	histocompatibility 2, class II antigen E beta	0.041	Mouse
Fas	Fas (TNF receptor superfamily member 6)	0.034
Rxra	retinoid X receptor alpha	0.034
Vhl	von Hippel-Lindau tumor suppressor	0.031
Itgb1	integrin beta 1 (fibronectin receptor beta)	0.029
Lyst	lysosomal trafficking regulator	0.022
H2-Ab1	histocompatibility 2, class II antigen A, beta 1	0.021
Lyz2	lysozyme 2	0.019
Crim1	cysteine rich transmembrane BMP regulator 1 (chordin like)	0.019
Irf8	interferon regulatory factor 8	0.016
Tcrb	T-cell receptor beta chain	0.016
Tgfb1	transforming growth factor, beta 1	0.015
Tcra	T-cell receptor alpha chain	0.014
Cdkn1a	cyclin-dependent kinase inhibitor 1A (P21)	0.014
Ehd3	EH-domain containing 3	0.012
Commd4	COMM domain containing 4	0.011
Bcl2l1	BCL2-like 1	0.011	Mouse