IMP
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adenylate cyclase inhibiting g protein coupled glutamate receptor signaling pathway
The series of molecular signals generated as a consequence of a G-protein coupled glutamate receptor binding to its physiological ligand, where the pathway proceeds with inhibition of adenylyl cyclase and a subsequent decrease in the concentration of cyclic AMP (cAMP).
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Click on a gene's description to view its network relationships with genes known to be involved in "adenylate cyclase inhibiting g protein coupled glutamate receptor signaling pathway"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| Grin2b | glutamate receptor, ionotropic, NMDA2B (epsilon 2) | 0.627 | ||
| Grin1 | glutamate receptor, ionotropic, NMDA1 (zeta 1) | 0.615 | ||
| Shank2 | SH3/ankyrin domain gene 2 | 0.259 | ||
| Dlgap1 | discs, large (Drosophila) homolog-associated protein 1 | 0.235 | ||
| Homer1 | homer homolog 1 (Drosophila) | 0.217 | ||
| Drd1a | dopamine receptor D1A | 0.070 | ||
| Fbxo41 | F-box protein 41 | 0.058 | ||
| Dlg2 | discs, large homolog 2 (Drosophila) | 0.058 | ||
| Mpped1 | metallophosphoesterase domain containing 1 | 0.044 | ||
| AI593442 | expressed sequence AI593442 | 0.041 | ||
| Shisa9 | shisa homolog 9 (Xenopus laevis) | 0.040 | ||
| Hs3st2 | heparan sulfate (glucosamine) 3-O-sulfotransferase 2 | 0.038 | ||
| Dsg1a | desmoglein 1 alpha | 0.036 | ||
| Prkce | protein kinase C, epsilon | 0.032 | ||
| Xkr4 | X Kell blood group precursor related family member 4 | 0.030 | ||
| Grik2 | glutamate receptor, ionotropic, kainate 2 (beta 2) | 0.030 | ||
| Adcy1 | adenylate cyclase 1 | 0.030 | ||
| Tmem198 | transmembrane protein 198 | 0.029 | ||
| 3110047P20Rik | RIKEN cDNA 3110047P20 gene | 0.029 | ||
| Emx1 | empty spiracles homolog 1 (Drosophila) | 0.028 | ||
| Gpr26 | G protein-coupled receptor 26 | 0.027 | ||
| Htr2a | 5-hydroxytryptamine (serotonin) receptor 2A | 0.025 | ||
| Arc | activity regulated cytoskeletal-associated protein | 0.025 | ||
| Cit | citron | 0.025 | ||
| Ankrd34b | ankyrin repeat domain 34B | 0.024 | ||
| 6430704M03Rik | RIKEN cDNA 6430704M03 gene | 0.024 | ||
| Accn4 | amiloride-sensitive cation channel 4, pituitary | 0.023 | ||
| Kctd8 | potassium channel tetramerisation domain containing 8 | 0.020 | ||
| Hecw1 | HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1 | 0.020 | ||
| Pou4f2 | POU domain, class 4, transcription factor 2 | 0.020 | ||
| Prrt1 | proline-rich transmembrane protein 1 | 0.019 | ||
| Csmd1 | CUB and Sushi multiple domains 1 | 0.019 | ||
| E130309F12Rik | RIKEN cDNA E130309F12 gene | 0.018 | ||
| Gpr123 | G protein-coupled receptor 123 | 0.017 | ||
| Clec2l | C-type lectin domain family, member L | 0.017 | ||
| Il1rapl1 | interleukin 1 receptor accessory protein-like 1 | 0.016 | ||
| Col19a1 | collagen, type XIX, alpha 1 | 0.016 | ||
| Iqsec3 | IQ motif and Sec7 domain 3 | 0.016 | ||
| Nxph1 | neurexophilin 1 | 0.016 | ||
| Krt84 | keratin 84 | 0.015 | ||
| Prrt3 | proline-rich transmembrane protein 3 | 0.014 | ||
| Camk2b | calcium/calmodulin-dependent protein kinase II, beta | 0.014 | ||
| Grik4 | glutamate receptor, ionotropic, kainate 4 | 0.014 | ||
| Grm5 | glutamate receptor, metabotropic 5 | 0.014 | Mouse | |
| Ina | internexin neuronal intermediate filament protein, alpha | 0.014 | ||
| Egfem1 | EGF-like and EMI domain containing 1 | 0.014 | ||
| Prkcb | protein kinase C, beta | 0.014 | ||
| Frmpd3 | FERM and PDZ domain containing 3 | 0.013 | ||
| Tmem132d | transmembrane protein 132D | 0.013 | ||
| Nsf | N-ethylmaleimide sensitive fusion protein | 0.013 | ||
| Camk2a | calcium/calmodulin-dependent protein kinase II alpha | 0.013 | ||
| Dmrtc1a | DMRT-like family C1a | 0.012 | ||
| Ankrd34a | ankyrin repeat domain 34A | 0.012 | ||
| Lingo3 | leucine rich repeat and Ig domain containing 3 | 0.012 | ||
| Olfm3 | olfactomedin 3 | 0.011 | ||
| Cpne4 | copine IV | 0.011 | ||
| Vwc2l | von Willebrand factor C domain-containing protein 2-like | 0.011 | ||
| Ptk2b | PTK2 protein tyrosine kinase 2 beta | 0.011 | ||
| Neurod6 | neurogenic differentiation 6 | 0.011 | ||
| Grm4 | glutamate receptor, metabotropic 4 | 0.011 | Human Mouse | |
| Tuba4a | tubulin, alpha 4A | 0.011 | ||
| Rims4 | regulating synaptic membrane exocytosis 4 | 0.010 | ||
| Slc6a3 | solute carrier family 6 (neurotransmitter transporter, dopamine), member 3 | 0.010 | ||
| Prkcc | protein kinase C, gamma | 0.010 | ||
| Kcnv1 | potassium channel, subfamily V, member 1 | 0.010 |