IMP
Process View
sequestering of bmp in extracellular matrix
Confining a bone morphogenetic protein (BMP) to the extracellular matrix (ECM), such that it is separated from other components of the signaling pathway, including its cell surface receptor. Bone morphogenetic proteins (BMPs) are secreted as homodimers, non-covalently associated with N-terminal pro-peptides, and are targeted to the extracellular matrix through interaction with matrix proteins.
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In addition to gene-name show these genes:
Click on a gene's description to view its network relationships with genes known to be involved in "sequestering of bmp in extracellular matrix"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| Lox | lysyl oxidase | 0.391 | ||
| Col1a1 | collagen, type I, alpha 1 | 0.235 | ||
| Eln | elastin | 0.153 | ||
| Tgfb2 | transforming growth factor, beta 2 | 0.132 | ||
| Mmp2 | matrix metallopeptidase 2 | 0.104 | ||
| Mmp14 | matrix metallopeptidase 14 (membrane-inserted) | 0.078 | ||
| Gli3 | GLI-Kruppel family member GLI3 | 0.046 | ||
| Col1a2 | collagen, type I, alpha 2 | 0.042 | ||
| Prrx2 | paired related homeobox 2 | 0.036 | ||
| Fgfr2 | fibroblast growth factor receptor 2 | 0.029 | ||
| Col6a1 | collagen, type VI, alpha 1 | 0.028 | ||
| Loxl1 | lysyl oxidase-like 1 | 0.026 | ||
| Tgfbr2 | transforming growth factor, beta receptor II | 0.024 | ||
| Fgfr1 | fibroblast growth factor receptor 1 | 0.023 | ||
| Col6a2 | collagen, type VI, alpha 2 | 0.022 | ||
| Pax3 | paired box gene 3 | 0.022 | ||
| Shh | sonic hedgehog | 0.021 | ||
| Col3a1 | collagen, type III, alpha 1 | 0.020 | ||
| Dbn1 | drebrin 1 | 0.020 | ||
| Sox9 | SRY-box containing gene 9 | 0.020 | ||
| Col5a1 | collagen, type V, alpha 1 | 0.019 | ||
| Ror2 | receptor tyrosine kinase-like orphan receptor 2 | 0.019 | ||
| Slc2a10 | solute carrier family 2 (facilitated glucose transporter), member 10 | 0.018 | ||
| Mfap4 | microfibrillar-associated protein 4 | 0.018 | ||
| Col11a1 | collagen, type XI, alpha 1 | 0.017 | ||
| Cd248 | CD248 antigen, endosialin | 0.016 | ||
| Col5a2 | collagen, type V, alpha 2 | 0.016 | ||
| Twist2 | twist homolog 2 (Drosophila) | 0.015 | ||
| Hoxd11 | homeobox D11 | 0.014 | ||
| Aebp1 | AE binding protein 1 | 0.013 | ||
| Lmna | lamin A | 0.013 | ||
| Gli2 | GLI-Kruppel family member GLI2 | 0.012 | ||
| Agtr2 | angiotensin II receptor, type 2 | 0.012 | ||
| Mfap5 | microfibrillar associated protein 5 | 0.012 | ||
| Col12a1 | collagen, type XII, alpha 1 | 0.011 | ||
| Col6a3 | collagen, type VI, alpha 3 | 0.011 | ||
| Agtr1a | angiotensin II receptor, type 1a | 0.011 | ||
| Tgfb3 | transforming growth factor, beta 3 | 0.011 | ||
| Creb3l1 | cAMP responsive element binding protein 3-like 1 | 0.011 | ||
| Atp7a | ATPase, Cu++ transporting, alpha polypeptide | 0.011 | ||
| Fbln1 | fibulin 1 | 0.010 | ||
| Pdgfra | platelet derived growth factor receptor, alpha polypeptide | 0.010 | ||
| Twist1 | twist homolog 1 (Drosophila) | 0.010 |