IMP

Process View

Mus musculus

6 genes annotated in mouse

barbed end actin filament capping

The binding of a protein or protein complex to the barbed (or plus) end of an actin filament, thus preventing the addition, exchange or removal of further actin subunits.

Loading network...

In addition to gene-name show these genes:

Known genes in the process in mouse Include functional analogs

Network Filters

Minimum relationship confidence:

Maximum number of genes:

Highlight known relationships in gold.

Graphical Options

Adjust edge length:

Adjust node size:

Fixed layout

Black background

Low confidence color:

Med confidence color:

High confidence color:

Hide the legend in the network

Save Options

Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "barbed end actin filament capping"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "barbed end actin filament capping" (in gray)

Name	Description	Probability	Func Analog Organism
Ywhaz	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide	0.999
Actr3	ARP3 actin-related protein 3 homolog (yeast)	0.999
Wdr1	WD repeat domain 1	0.996	Yeast
Rac1	RAS-related C3 botulinum substrate 1	0.968
Cdc42	cell division cycle 42 homolog (S. cerevisiae)	0.964
Arpc4	actin related protein 2/3 complex, subunit 4	0.850
Rap1b	RAS related protein 1b	0.813
Capzb	capping protein (actin filament) muscle Z-line, beta	0.761
Msn	moesin	0.619
Ywhah	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide	0.572
Mobkl1b	MOB1, Mps One Binder kinase activator-like 1B (yeast)	0.537
Cltc	clathrin, heavy polypeptide (Hc)	0.525
Bzw1	basic leucine zipper and W2 domains 1	0.366
Rhoa	ras homolog gene family, member A	0.359
Gnb1	guanine nucleotide binding protein (G protein), beta 1	0.302
Bcl10	B-cell leukemia/lymphoma 10	0.259
Capza2	capping protein (actin filament) muscle Z-line, alpha 2	0.256	Mouse
Actr2	ARP2 actin-related protein 2 homolog (yeast)	0.212
Vasp	vasodilator-stimulated phosphoprotein	0.194
Psap	prosaposin	0.177
Rod1	ROD1 regulator of differentiation 1 (S. pombe)	0.168
Sdcbp	syndecan binding protein	0.162
Arf1	ADP-ribosylation factor 1	0.151
Fam49b	family with sequence similarity 49, member B	0.151
Calm1	calmodulin 1	0.142
Akt1	thymoma viral proto-oncogene 1	0.132
Dbnl	drebrin-like	0.129
Atp6v1a	ATPase, H+ transporting, lysosomal V1 subunit A	0.128
Sept7	septin 7	0.118
Tmod3	tropomodulin 3	0.110
Stx7	syntaxin 7	0.106
Gnb2	guanine nucleotide binding protein (G protein), beta 2	0.094
Arpc2	actin related protein 2/3 complex, subunit 2	0.092
Cfl1	cofilin 1, non-muscle	0.088
Arhgap1	Rho GTPase activating protein 1	0.084
Mtpn	myotrophin	0.075	Human
Pfn1	profilin 1	0.072
Prkar1a	protein kinase, cAMP dependent regulatory, type I, alpha	0.062
Capza1	capping protein (actin filament) muscle Z-line, alpha 1	0.061
Csrp1	cysteine and glycine-rich protein 1	0.059
Ugdh	UDP-glucose dehydrogenase	0.059
Actg1	actin, gamma, cytoplasmic 1	0.056
Azin1	antizyme inhibitor 1	0.055
Acbd3	acyl-Coenzyme A binding domain containing 3	0.046
Acot9	acyl-CoA thioesterase 9	0.044
Lgmn	legumain	0.041
Wsb2	WD repeat and SOCS box-containing 2	0.040
Nipa2	non imprinted in Prader-Willi/Angelman syndrome 2 homolog (human)	0.038
Sri	sorcin	0.038
Slc25a24	solute carrier family 25 (mitochondrial carrier, phosphate carrier), member 24	0.038
Serp1	stress-associated endoplasmic reticulum protein 1	0.038
Hif1a	hypoxia inducible factor 1, alpha subunit	0.036
Cttn	cortactin	0.036
Lrrk2	leucine-rich repeat kinase 2	0.036
Ugcg	UDP-glucose ceramide glucosyltransferase	0.036
Cap1	CAP, adenylate cyclase-associated protein 1 (yeast)	0.033
Cdc42se1	CDC42 small effector 1	0.032
Gna13	guanine nucleotide binding protein, alpha 13	0.030
Snx2	sorting nexin 2	0.030
Coro1c	coronin, actin binding protein 1C	0.030
Klf6	Kruppel-like factor 6	0.028
Lims1	LIM and senescent cell antigen-like domains 1	0.026
Rab7	RAB7, member RAS oncogene family	0.026
Tpm4	tropomyosin 4	0.026
Pitpna	phosphatidylinositol transfer protein, alpha	0.026
Nras	neuroblastoma ras oncogene	0.025
Abi1	abl-interactor 1	0.025
Adam10	a disintegrin and metallopeptidase domain 10	0.023
Arf4	ADP-ribosylation factor 4	0.022
Ptp4a2	protein tyrosine phosphatase 4a2	0.022
Map2k1	mitogen-activated protein kinase kinase 1	0.022
Rap2c	RAP2C, member of RAS oncogene family	0.021
Actn1	actinin, alpha 1	0.020
Ykt6	YKT6 homolog (S. Cerevisiae)	0.020
Snx6	sorting nexin 6	0.019
Arl6ip5	ADP-ribosylation factor-like 6 interacting protein 5	0.019
Pdia3	protein disulfide isomerase associated 3	0.019
Ppp1ca	protein phosphatase 1, catalytic subunit, alpha isoform	0.019
Pafah1b2	platelet-activating factor acetylhydrolase, isoform 1b, subunit 2	0.019
Ube2d3	ubiquitin-conjugating enzyme E2D 3 (UBC4/5 homolog, yeast)	0.019
Cyb5r4	cytochrome b5 reductase 4	0.018
Agfg1	ArfGAP with FG repeats 1	0.018
Ilk	integrin linked kinase	0.017
Cab39	calcium binding protein 39	0.017
Gng10	guanine nucleotide binding protein (G protein), gamma 10	0.017
Kif5b	kinesin family member 5B	0.016
Vmp1	vacuole membrane protein 1	0.016
Pgm1	phosphoglucomutase 1	0.016
Ppp4c	protein phosphatase 4, catalytic subunit	0.015
Pdlim5	PDZ and LIM domain 5	0.015
Spg21	spastic paraplegia 21 homolog (human)	0.015
Arpc5	actin related protein 2/3 complex, subunit 5	0.015
Atp1b3	ATPase, Na+/K+ transporting, beta 3 polypeptide	0.015
Usp22	ubiquitin specific peptidase 22	0.015
Tmed7	transmembrane emp24 protein transport domain containing 7	0.015
Scamp2	secretory carrier membrane protein 2	0.015
Ap2a2	adaptor protein complex AP-2, alpha 2 subunit	0.015
Ube2n	ubiquitin-conjugating enzyme E2N	0.014
Cyfip1	cytoplasmic FMR1 interacting protein 1	0.014
Dctn5	dynactin 5	0.013
Rab11a	RAB11a, member RAS oncogene family	0.013
Gsr	glutathione reductase	0.013
M6pr	mannose-6-phosphate receptor, cation dependent	0.012
Rab1	RAB1, member RAS oncogene family	0.012
Abhd12	abhydrolase domain containing 12	0.012
Eif4a1	eukaryotic translation initiation factor 4A1	0.012
Dnajc5	DnaJ (Hsp40) homolog, subfamily C, member 5	0.012
Mapk3	mitogen-activated protein kinase 3	0.011
Spna2	spectrin alpha 2	0.011
Adss	adenylosuccinate synthetase, non muscle	0.011
3110003A17Rik	RIKEN cDNA 3110003A17 gene	0.011
Leprotl1	leptin receptor overlapping transcript-like 1	0.011
Gdi2	guanosine diphosphate (GDP) dissociation inhibitor 2	0.011
Nipsnap3b	nipsnap homolog 3B (C. elegans)	0.011
Prr13	proline rich 13	0.010
Clic1	chloride intracellular channel 1	0.010
Nptn	neuroplastin	0.010
Arpc3	actin related protein 2/3 complex, subunit 3	0.010
Atp6v1c1	ATPase, H+ transporting, lysosomal V1 subunit C1	0.010
Gorasp2	golgi reassembly stacking protein 2	0.010