IMP

Process View

Rattus norvegicus

10 genes annotated in rat

Multi-species View

positive regulation of leukocyte chemotaxis

GO:0002690

Any process that activates or increases the frequency, rate, or extent of leukocyte chemotaxis.

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Known genes in the process in rat Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "positive regulation of leukocyte chemotaxis"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "positive regulation of leukocyte chemotaxis" (in gray)

Name	Description	Probability	Func Analog Organism
Ccl2	chemokine (C-C motif) ligand 2	0.996
Cxcl10	chemokine (C-X-C motif) ligand 10	0.924
Il6	interleukin 6	0.695
Ccl4	chemokine (C-C motif) ligand 4	0.658	Human Rat
Il1b	interleukin 1 beta	0.628
Cxcl2	chemokine (C-X-C motif) ligand 2	0.541	Rat
Cd14	CD14 molecule	0.524
Cxcl1	chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)	0.437	Rat
RT1-Ba	RT1 class II, locus Ba	0.387
Il1a	interleukin 1 alpha	0.379
Ccl7	chemokine (C-C motif) ligand 7	0.359	Rat
Ccl3	chemokine (C-C motif) ligand 3	0.350	Human Rat
Il2rg	interleukin 2 receptor, gamma	0.338
Tcrb	T-cell receptor beta chain	0.137
Cd53	Cd53 molecule	0.127
Hck	hemopoietic cell kinase	0.109
Il8rb	interleukin 8 receptor, beta	0.098
Ccr5	chemokine (C-C motif) receptor 5	0.097
RT1-Da	RT1 class II, locus Da	0.092
Icam1	intercellular adhesion molecule 1	0.089
Serpine1	serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1	0.088	Human
Nkg7	natural killer cell group 7 sequence	0.080
RT1-Bb	RT1 class II, locus Bb	0.080
Elk3	ELK3, ETS-domain protein	0.073
Ccl20	chemokine (C-C motif) ligand 20	0.073	Rat
Fosl1	fos-like antigen 1	0.072
Ptger4	prostaglandin E receptor 4 (subtype EP4)	0.069
Plek	pleckstrin	0.069
Plau	plasminogen activator, urokinase	0.068
Mrgprf	MAS-related GPR, member F	0.067
Pla2g2a	phospholipase A2, group IIA (platelets, synovial fluid)	0.065
Il2rb	interleukin 2 receptor, beta	0.064
Thbd	thrombomodulin	0.063
Reg3g	regenerating islet-derived 3 gamma	0.059
Casp1	caspase 1	0.055
Cd68	Cd68 molecule	0.053
Ccr2	chemokine (C-C motif) receptor 2	0.053	Human Mouse Rat
Cd37	CD37 molecule	0.051
Igsf6	immunoglobulin superfamily, member 6	0.051
Laptm5	lysosomal protein transmembrane 5	0.048
Ptprc	protein tyrosine phosphatase, receptor type, C	0.047
Socs3	suppressor of cytokine signaling 3	0.046
St8sia4	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4	0.045
Olr1	oxidized low density lipoprotein (lectin-like) receptor 1	0.039
Cd83	CD83 molecule	0.039
Calcrl	calcitonin receptor-like	0.039
Ubd	ubiquitin D	0.039
Reg3b	regenerating islet-derived 3 beta	0.035
Rhoj	ras homolog gene family, member J	0.033
Col12a1	collagen, type XII, alpha 1	0.033
Edn1	endothelin 1	0.032
Tyrobp	Tyro protein tyrosine kinase binding protein	0.032
P2ry6	pyrimidinergic receptor P2Y, G-protein coupled, 6	0.030
Klrd1	killer cell lectin-like receptor, subfamily D, member 1	0.030
Jak1	Janus kinase 1	0.030
Sele	selectin E	0.030	Rat
Fcn1	ficolin (collagen/fibrinogen domain containing) 1	0.029
Gzmb	granzyme B	0.029
F2rl2	coagulation factor II (thrombin) receptor-like 2	0.029
Prkacb	protein kinase, cAMP dependent, catalytic, beta	0.028
Il1rn	interleukin 1 receptor antagonist	0.028
Slco2b1	solute carrier organic anion transporter family, member 2b1	0.028
Ly86	lymphocyte antigen 86	0.028
Rab20	RAB20, member RAS oncogene family	0.027
Xcl1	chemokine (C motif) ligand 1	0.027	Human Rat
Gzmk	granzyme K	0.026
Pla2g4a	phospholipase A2, group IVA (cytosolic, calcium-dependent)	0.026
Cd86	CD86 molecule	0.025
F2rl1	coagulation factor II (thrombin) receptor-like 1	0.025	Human
Pld4	phospholipase D family, member 4	0.024
Neurl3	neuralized homolog 3 (Drosophila)	0.024
Cd8a	CD8a molecule	0.023
Ptgs2	prostaglandin-endoperoxide synthase 2	0.023
Lilrb4	leukocyte immunoglobulin-like receptor, subfamily B, member 4	0.023
Csf2rb	colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)	0.023
F13a1	coagulation factor XIII, A1 polypeptide	0.022
Cd69	Cd69 molecule	0.022
Timp3	TIMP metallopeptidase inhibitor 3	0.022
Mmp3	matrix metallopeptidase 3	0.020
Iapp	islet amyloid polypeptide	0.019
Cxcl11	chemokine (C-X-C motif) ligand 11	0.019
S1pr2	sphingosine-1-phosphate receptor 2	0.019
Cd4	Cd4 molecule	0.019
Cd44	Cd44 molecule	0.018
Timp1	TIMP metallopeptidase inhibitor 1	0.017
Tfpi2	tissue factor pathway inhibitor 2	0.017
Met	met proto-oncogene	0.016
Arl5c	ADP-ribosylation factor-like 5C	0.016
Itgad	integrin, alpha D	0.016
Arhgdib	Rho, GDP dissociation inhibitor (GDI) beta	0.016
Tmem88	transmembrane protein 88	0.016
Sell	selectin L	0.015
Lyn	v-yes-1 Yamaguchi sarcoma viral related oncogene homolog	0.015
Ngf	nerve growth factor (beta polypeptide)	0.015
Ly6c	Ly6-C antigen	0.014
Cfd	complement factor D (adipsin)	0.014
Fgfr2	fibroblast growth factor receptor 2	0.014
Mmp12	matrix metallopeptidase 12	0.013
Slpi	secretory leukocyte peptidase inhibitor	0.013
Ch25h	cholesterol 25-hydroxylase	0.013
Il1r2	interleukin 1 receptor, type II	0.013
Cd38	CD38 molecule	0.013
Bcl2a1d	B-cell leukemia/lymphoma 2 related protein A1d	0.013
Ccl11	chemokine (C-C motif) ligand 11	0.013	Rat
Csf1	colony stimulating factor 1 (macrophage)	0.012
Irf1	interferon regulatory factor 1	0.012
Tnf	tumor necrosis factor (TNF superfamily, member 2)	0.012
Zcwpw1	zinc finger, CW-type with PWWP domain 1	0.012
Utrn	utrophin	0.012
Areg	amphiregulin	0.012
Nek9	NIMA (never in mitosis gene a)- related kinase 9	0.011
Ifit3	interferon-induced protein with tetratricopeptide repeats 3	0.011
Clec2d	C-type lectin domain family 2, member d	0.011
Col8a1	collagen, type VIII, alpha 1	0.011
Hpgds	hematopoietic prostaglandin D synthase	0.011
Asgr2	asialoglycoprotein receptor 2	0.011
Has2	hyaluronan synthase 2	0.011
Mmp2	matrix metallopeptidase 2	0.010
Gimap5	GTPase, IMAP family member 5	0.010